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Most cited papers from WiCell

What are the most cited papers from WiCell?

The most cited paper from WiCell is "Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells" (Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto et al., 2007), with 10,385 citations. Next come "Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling" (1,794) and "Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells" (1,416).

Showing 50 of 58 papers. Every paper with more than 176 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto et al. · Science 20 Nov 2007 10,385
2 Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling Xiaojun Lance Lian, Cheston Hsiao, Gisela F. Wilson et al. · Proceedings of the National Academy of Sciences Open access 29 May 2012 1,794
3 Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells Jianhua Zhang, Gisela F. Wilson, Andrew G. Soerens et al. · Circulation Research Open access 12 Feb 2009 1,416
4 Effect of conjugated linoleic acid on body composition in mice Yeonhwa Park, KAREN J. ALBRIGHT, Wei Liu et al. · Lipids Aug 1997 1,167
5 BMP4 initiates human embryonic stem cell differentiation to trophoblast Ren‐He Xu, Xin Chen, Dong S. Li et al. · Nature Biotechnology 11 Nov 2002 1,156
6 Derivation of human embryonic stem cells in defined conditions Tenneille E. Ludwig, Mark E. Levenstein, Jeffrey M. Jones et al. · Nature Biotechnology 2006 1,129
7 The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus) Ray Ming et al. · Nature Open access Apr 2008 1,121
8 Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells Ren‐He Xu, Ruthann M. Peck, Dong S. Li et al. · Nature Methods 17 Feb 2005 982
9 Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid Yeong Lae Ha, Nancy K. Grimm, Michael W. Pariza · Carcinogenesis 1987 930
10 Whole-Genome Analysis of Histone H3 Lysine 4 and Lysine 27 Methylation in Human Embryonic Stem Cells Guangjin Pan, Shulan Tian, Jeff Nie et al. · Cell stem cell Open access Sep 2007 748
11 Feeder-independent culture of human embryonic stem cells Tenneille E. Ludwig, Veit Bergendahl, Mark E. Levenstein et al. · Nature Methods 21 Jul 2006 696
12 Nanog and transcriptional networks in embryonic stem cell pluripotency Guangjin Pan, James Alexander Thomson · Cell Research 2007 630
13 Human embryonic stem cell–derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential Maxim A. Vodyanik, Jack A. Bork, James Alexander Thomson et al. · Blood 17 Sep 2004 620
14 Simultaneous occurrence of fumonisin B1 and other mycotoxins in moldy corn collected from the People's Republic of China in regions with high incidences of esophageal cancer F S Chu, G Y Li · Applied and Environmental Microbiology Open access Mar 1994 531
15 NANOG Is a Direct Target of TGFβ/Activin-Mediated SMAD Signaling in Human ESCs Ren‐He Xu, Tori L. Sampsell-Barron, Feng Gu et al. · Cell stem cell Open access Aug 2008 524
16 Pax6 Is a Human Neuroectoderm Cell Fate Determinant Xiaoqing Zhang, Cindy Tzu-Ling Huang, Jing Chen et al. · Cell stem cell Open access Jul 2010 507
17 Directed Differentiation of Dopaminergic Neuronal Subtypes from Human Embryonic Stem Cells Yiping Yan, Dali Yang, Ewa D. Żarnowska et al. · Stem Cells Open access 25 May 2005 493
18 Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells Kyung-Dal Choi, Junying Yu, Kim Smuga-Otto et al. · Stem Cells Open access Mar 2009 466
19 Basic Fibroblast Growth Factor Support of Human Embryonic Stem Cell Self-Renewal Mark E. Levenstein, Tenneille E. Ludwig, Ren‐He Xu et al. · Stem Cells Open access 10 Nov 2005 458
20 Extracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem Cells Jianhua Zhang, Matthew Klos, Gisela F. Wilson et al. · Circulation Research Open access 22 Aug 2012 456
21 Estimation of human dose of staphylococcal enterotoxin A from a large outbreak of staphylococcal food poisoning involving chocolate milk Mary L. Evenson, M W Hinds, Robert S. Bernstein et al. · International Journal of Food Microbiology Dec 1988 388
22 Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures Maxim A. Vodyanik, James Alexander Thomson, Igor I. Slukvin · Blood Open access 6 Jun 2006 388
23 Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions Jeanette K. Beers, Daniel R. Gulbranson, Nicole George et al. · Nature Protocols Open access 25 Oct 2012 377
24 Conjugated Linoleic Acid (CLA) Content of Milk from Cows Offered Diets Rich in Linoleic and Linolenic Acid T.R. Dhiman, Larry D. Satter, Michael W. Pariza et al. · Journal of Dairy Science Open access May 2000 353
25 Perspective on the safety and effectiveness of conjugated linoleic acid Michael W. Pariza · American Journal of Clinical Nutrition Open access Jun 2004 351
26 Safety assessment of polylactide (PLA) for use as a food-contact polymer Robin Eichen Conn, Jeff Kolstad, Joseph F. Borzelleca et al. · Food and Chemical Toxicology Apr 1995 343
27 Karyotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells Seth M. Taapken, Benjamin S. Nisler, Michael A. Newton et al. · Nature Biotechnology Apr 2011 338
28 A Mesoderm-Derived Precursor for Mesenchymal Stem and Endothelial Cells Maxim A. Vodyanik, Junying Yu, Xin Zhang et al. · Cell stem cell Open access Dec 2010 331
29 Directed Neural Differentiation of Human Embryonic Stem Cells via an Obligated Primitive Anterior Stage Matthew T Pankratz, Xue Jun Li, Timothy M. LaVaute et al. · Stem Cells Open access Mar 2007 321
30 Review of Studies on the Thermal Resistance of Salmonellae M. Ellin Doyle, Alejandro S. Mazzotta · Journal of Food Protection Open access Jun 2000 312
31 The trans-10,cis-12 Isomer of Conjugated Linoleic Acid Downregulates Stearoyl-CoA Desaturase 1 Gene Expression in 3T3-L1 Adipocytes Young–Jin Choi, Young‐Cheul Kim, Yong-Bong Han et al. · Journal of Nutrition Open access Aug 2000 308
32 Plasma‐enhanced deposition of silver nanoparticles onto polymer and metal surfaces for the generation of antimicrobial characteristics Hongquan Jiang, Sorin O. Manolache, Amy C. Lee Wong et al. · Journal of Applied Polymer Science 7 May 2004 298
33 Differentiation of spinal motor neurons from pluripotent human stem cells Baoyang Hu, Su‐Chun Zhang · Nature Protocols Open access 20 Aug 2009 296
34 Protection of conjugated linoleic acids against 2-amino-3-methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms Christina Liew, Herman A.J. Schut, S.F. Chin et al. · Carcinogenesis 1995 286
35 Quality Control Guidelines for Clinical-Grade Human Induced Pluripotent Stem Cell Lines Stephen K. Sullivan et al. · Regenerative Medicine Open access 12 Sep 2018 284
36 A beef-derived mutagenesis modulator inhibits initiation of mouse epidermal tumors by 7,12-dimethylbenz[a]anthracene Michael W. Pariza, Walter A. Hargraves · Carcinogenesis 1985 279
37 A defined glycosaminoglycan-binding substratum for human pluripotent stem cells Joseph R. Klim, Lingyin Li, Paul J. Wrighton et al. · Nature Methods Open access 14 Nov 2010 272
38 Heat Resistance of Listeria monocytogenes M. Ellin Doyle, Alejandro S. Mazzotta, Timothy Cragin Wang et al. · Journal of Food Protection Open access Mar 2001 267
39 Prevalence and clonal nature of Escherichia coli O157:H7 on dairy farms in Wisconsin N. G. Faith, J. A. Shere, Roland Brosch et al. · Applied and Environmental Microbiology Open access May 1996 263
40 Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells Kejin Hu, Junying Yu, Kran Suknuntha et al. · Blood Open access 4 Feb 2011 260
41 Differentiation of human oligodendrocytes from pluripotent stem cells Baoyang Hu, Zhongwei Du, Su‐Chun Zhang · Nature Protocols Open access 15 Oct 2009 256
42 Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver Michele A. Battle, Geneviève Konopka, Fereshteh Parviz et al. · Proceedings of the National Academy of Sciences 19 May 2006 246
43 Evaluating the Safety of Microbial Enzyme Preparations Used in Food Processing: Update for a New Century Michael W. Pariza, Eric A. Johnson · Regulatory Toxicology and Pharmacology Apr 2001 238
44 Random-set methods identify distinct aspects of the enrichment signal in gene-set analysis Michael A. Newton, O A. Quintana, Johan A. den Boon et al. 5 Oct 2016 237
45 Escherichia coli O157:H7: Epidemiology, Pathogenesis, and Methods for Detection in Food Nisha V. Padhye, Michael P. Doyle · Journal of Food Protection Open access Jul 1992 234
46 3-D microwell culture of human embryonic stem cells Jeffrey C. Mohr, Juan Pablo, Sean P. Palecek · Biomaterials 2 Aug 2006 232
47 Recurrent copy number variations in human induced pluripotent stem cells Kristen Martins‐Taylor, Benjamin S. Nisler, Seth M. Taapken et al. · Nature Biotechnology Jun 2011 227
48 A germ cell origin of embryonic stem cells? Thomas P. Zwaka, James Alexander Thomson · Development 28 Dec 2004 225
49 The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells Jeffrey C. Mohr, Jianhua Zhang, Samira Michelle Azarin et al. · Biomaterials Open access 29 Nov 2009 223
50 Identification and purification of a new staphylococcal enterotoxin, H Yu‐Chieh Su, Amy C. Lee Wong · Applied and Environmental Microbiology Open access Apr 1995 217

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.