Most cited papers from WuXi AppTec (China)

WuXi AppTec (China)

What are the most cited papers from WuXi AppTec (China)?

The most cited paper from WuXi AppTec (China) is "Deep learning enables rapid identification of potent DDR1 kinase inhibitors" (Alex A. Zhavoronkov et al., 2019), with 1,616 citations. Next come "Triazole derivatives and their anti-tubercular activity" (499) and "International Cooperation to Enable the Diagnosis of All Rare Genetic Diseases" (475).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 114 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Deep learning enables rapid identification of potent DDR1 kinase inhibitors Alex A. Zhavoronkov et al. · Nature Biotechnology	Sep 2019	1,616
2	Triazole derivatives and their anti-tubercular activity Shu Zhang, Zhi Gang Xu, Chuan Gao et al. · European Journal of Medicinal Chemistry Open access	27 Jun 2017	499
3	International Cooperation to Enable the Diagnosis of All Rare Genetic Diseases Kym M. Boycott et al. · The American Journal of Human Genetics Open access	May 2017	475
4	Robotic grinding of complex components: A step towards efficient and intelligent machining – challenges, solutions, and applications Dahu Zhu, Xiaozhi Feng, Xiaohu Xu et al. · Robotics and Computer-Integrated Manufacturing	15 May 2020	428
5	Genomic portrait of resectable hepatocellular carcinomas: Implications of RB1 and FGF19 aberrations for patient stratification Sung‐Min Ahn et al. · Hepatology Open access	3 May 2014	424
6	Novel lignin-based single atom catalysts as peroxymonosulfate activator for pollutants degradation: Role of single cobalt and electron transfer pathway Yuanfeng Qi, Jing Li, Yanqing Zhang et al. · Applied Catalysis B: Environmental	21 Jan 2021	404
7	Quinoline hybrids and their antiplasmodial and antimalarial activities Yuan‐Qiang Hu, Chuan Gao, Shu Zhang et al. · European Journal of Medicinal Chemistry Open access	27 Jul 2017	383
8	Optimized arylomycins are a new class of Gram-negative antibiotics Peter A. Smith et al. · Nature	Sep 2018	369
9	A Review on the Pd-Based Three-Way Catalyst Jihui Wang, Hong Chen, Zhicheng Hu et al. · Catalysis Reviews	25 Nov 2014	325
10	Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma Yongping Cui et al. · Cell Research Open access	12 May 2020	323
11	Accelerating the energy transition to achieve carbon neutrality Lizette De La Peña, Ru Guo, Xiaojing Cao et al. · Resources Conservation and Recycling	14 Oct 2021	317
12	Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia Benshang Li et al. · Blood Open access	24 Oct 2019	309
13	Recent advances of pyrazole-containing derivatives as anti-tubercular agents Zhi Gang Xu, Chuan Gao, Qing-Cheng Ren et al. · European Journal of Medicinal Chemistry Open access	3 Aug 2017	293
14	Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition Aaron Boudreau et al. · Nature Chemical Biology Open access	Aug 2016	283
15	Current and Future Roles of Artificial Intelligence in Medicinal Chemistry Synthesis Thomas J. Struble et al. · Journal of Medicinal Chemistry Open access	3 Apr 2020	263
16	Isatin hybrids and their anti-tuberculosis activity Zhi Gang Xu, Shu Zhang, Chuan Gao et al. · Chinese Chemical Letters	10 Aug 2016	260
17	Direct Laser Writing of Graphene Made from Chemical Vapor Deposition for Flexible, Integratable Micro‐Supercapacitors with Ultrahigh Power Output Jianglin Ye, Huabing Tan, Shuilin Wu et al. · Advanced Materials Open access	17 May 2018	242
18	Recent developments of coumarin-containing derivatives and their anti-tubercular activity Yuan‐Qiang Hu, Zhi Gang Xu, Shu Zhang et al. · European Journal of Medicinal Chemistry	2 May 2017	239
19	Isoniazid derivatives and their anti-tubercular activity Yuan‐Qiang Hu, Shu Zhang, Feng Zhao et al. · European Journal of Medicinal Chemistry	3 Apr 2017	237
20	4-Quinolone hybrids and their antibacterial activities Yuan‐Qiang Hu, Shu Zhang, Zhi Gang Xu et al. · European Journal of Medicinal Chemistry	28 Sep 2017	225
21	Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity Thomas H. Pillow et al. · ChemMedChem	31 Oct 2019	207
22	Discovery of MK‐8742: An HCV NS5A Inhibitor with Broad Genotype Activity Craig A. Coburn, Peter T. Meinke, Wei Chang et al. · ChemMedChem	14 Oct 2013	200
23	Structural basis for dual-mode inhibition of the ABC transporter MsbA Hoangdung Ho et al. · Nature	26 Apr 2018	184
24	Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy Peter S. Dragovich et al. · Journal of Medicinal Chemistry	17 Feb 2021	182
25	Preparation, characteristics and assessment of a novel gelatin–chitosan sponge scaffold as skin tissue engineering material Fei Han, Yang Dong, Zhen Su et al. · International Journal of Pharmaceutics	Oct 2014	177
26	1,2,3‐Triazole hybrids with anti‐HIV‐1 activity Lian‐Shun Feng, Man‐Jie Zheng, Feng Zhao et al. · Archiv der Pharmazie	22 Sep 2020	170
27	Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments Michalina Janiszewska et al. · Nature Cell Biology Open access	Jul 2019	169
28	Lung cancer in never-smoker Asian females is driven by oncogenic mutations, most often involving EGFR Sang Yun Ha, So‐Jung Choi, Jong Ho Cho et al. · Oncotarget Open access	28 Feb 2015	163
29	Recent advances of tetrazole derivatives as potential anti-tubercular and anti-malarial agents Chuan Gao, Le Chang, Zhi Gang Xu et al. · European Journal of Medicinal Chemistry Open access	3 Dec 2018	160
30	Recombinase-mediated cassette exchange (RMCE) — A rapidly-expanding toolbox for targeted genomic modifications Soeren Turan, Christoph Zehe, Johannes Kuehle et al. · Gene	29 Nov 2012	160
31	Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates Leanna R. Staben et al. · Nature Chemistry	17 Oct 2016	156
32	Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium (KLCC-12-02) Ji Yun Lee, XU Qing, Xiumin Wei et al. · Oncotarget Open access	9 Jan 2016	156
33	Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties Peter S. Dragovich et al. · Journal of Medicinal Chemistry	17 Feb 2021	154
34	Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models Waleed Minzel et al. · Cell Open access	23 Aug 2018	154
35	MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment Douglas D. Fang, Qiuqiong Tang, Yanhui Kong et al. · Journal for ImmunoTherapy of Cancer Open access	28 Nov 2019	152
36	Itraconazole IV nanosuspension enhances efficacy through altered pharmacokinetics in the rat Barrett E. Rabinow, James Kipp, Pavlos Papadopoulos et al. · International Journal of Pharmaceutics	4 Mar 2007	152
37	Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase Justin T. Ernst et al. · Journal of Medicinal Chemistry Open access	29 May 2020	149
38	Seasonal succession and spatial distribution of bacterial community structure in a eutrophic freshwater Lake, Lake Taihu Congmin Zhu, Junyi Zhang, Muhammad Zohaib Nawaz et al. · The Science of The Total Environment	8 Mar 2019	145
39	Physical stability of pharmaceutical formulations: solid-state characterization of amorphous dispersions Yushen Guo, Evgenyi Shalaev, Scott R. Smith · TrAC Trends in Analytical Chemistry	20 Jun 2013	145
40	GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer Jun Liang et al. · Journal of Medicinal Chemistry Open access	12 Jul 2021	142
41	A new wave of innovations within the DNA damage response Qi Li, Wenyuan Qian, Yang Zhang et al. · Signal Transduction and Targeted Therapy Open access	7 Sep 2023	140
42	Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer Shuaishuai Teng, Yang Eric Li, Ming Yang et al. · Cell Research Open access	6 Dec 2019	138
43	GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) F. Anthony Romero et al. · Journal of Medicinal Chemistry Open access	11 Sep 2017	137
44	Application of novel force control strategies to enhance robotic abrasive belt grinding quality of aero-engine blades Xiaohu Xu, Dahu Zhu, Haiyang Zhang et al. · Chinese Journal of Aeronautics Open access	14 Feb 2019	132
45	Soft transparent graphene contact lens electrodes for conformal full-cornea recording of electroretinogram Rongkang Yin, Zheng Jin Xu, Ming Mei et al. · Nature Communications Open access	7 Jun 2018	132
46	Chitin–calcium alginate composite fibers for wound care dressings spun from ionic liquid solution Julia L. Shamshina, Gabriela Gurău, Leah E. Block et al. · Journal of Materials Chemistry B	2014	132
47	Freezing of Biologicals Revisited: Scale, Stability, Excipients, and Degradation Stresses Jean‐René Authelin, Miguel Ângelo Rodrigues, Serguei Tchessalov et al. · Journal of Pharmaceutical Sciences Open access	6 Nov 2019	131
48	The study on the coarsening process and precipitation strengthening of Al3Er precipitate in Al–Er binary alloy Yi Zhang, Kunyuan Gao, Shengping Wen et al. · Journal of Alloys and Compounds	30 Apr 2014	131
49	Failure mechanisms in flexible electronics Zhehui Zhao, Haoran Fu, Ruitao Tang et al. · International Journal of Smart and Nano Materials Open access	27 Sep 2023	130
50	Lead identification of novel and selective TYK2 inhibitors Jun Liang et al. · European Journal of Medicinal Chemistry Open access	14 May 2013	127

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.