| 1 |
Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial
Wei Tang et al. · BMJ
Open access |
14 May 2020 |
1,058 |
| 2 |
Hydroxychloroquine in patients mainly with mild to moderate COVID–19: an open–label, randomized, controlled trial
Wei Tang et al. · medRxiv
PreprintOpen access |
14 Apr 2020 |
198 |
| 3 |
Fecal microbiota transplantation plus tislelizumab and fruquintinib in refractory microsatellite stable metastatic colorectal cancer: an open-label, single-arm, phase II trial (RENMIN-215)
Wensi Zhao, Jun Lei, Shaobo Ke et al. · EClinicalMedicine
Open access |
14 Nov 2023 |
136 |
| 4 |
High Expression Levels of AGGF1 and MFAP4 Predict Primary Platinum-Based Chemoresistance and are Associated with Adverse Prognosis in Patients with Serous Ovarian Cancer
Haiyue Zhao, Qian Sun, Lisong Li et al. · Journal of Cancer
Open access |
2019 |
65 |
| 5 |
Saccharomyces boulardii Combined With Quadruple Therapy for Helicobacter pylori Eradication Decreased the Duration and Severity of Diarrhea: A Multi-Center Prospective Randomized Controlled Trial
Yuchong Zhao, Yilei Yang, Aruna et al. · Frontiers in Medicine
Open access |
18 Nov 2021 |
36 |
| 6 |
Targeted resequencing reveals genetic risks in patients with sporadic idiopathic pulmonary fibrosis
Yanhan Deng et al. · Human Mutation
Open access |
19 Jun 2018 |
36 |
| 7 |
Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China
Qixia Luo et al. · Nature Communications
Open access |
14 Apr 2025 |
35 |
| 8 |
Cholesterol inhibits entotic cell-in-cell formation and actomyosin contraction
Banzhan Ruan et al. · Biochemical and Biophysical Research Communications
|
Dec 2017 |
29 |
| 9 |
Upregulation of Phosphodiesterase type 5 in the Hyperplastic Prostate
Wenhao Zhang, Ning Zang, Yaoming Jiang et al. · Scientific Reports
Open access |
10 Dec 2015 |
25 |
| 10 |
Effect of omega 3 fatty acids on C-reactive protein and interleukin-6 in patients with advanced nonsmall cell lung cancer
Yan Lu, Ren-gang Chen, San-zou Wei et al. · Medicine
Open access |
Sep 2018 |
24 |
| 11 |
Acupuncture and moxibustion combined with cupping for the treatment of post-herpetic neuralgia
Qiujun Zhou, Shenyu Wei, Haijia Zhu et al. · Medicine
Open access |
6 Aug 2021 |
21 |
| 12 |
The effect of using simethicone with or without N-acetylcysteine before gastroscopy: A meta-analysis and systemic review
Yuanfa Li, Fangjuan Du, Dou Fu · Saudi Journal of Gastroenterology
ReviewOpen access |
2019 |
21 |
| 13 |
Heparin administration at first medical contact vs immediately before primary percutaneous coronary intervention: the HELP-PCI trial
Jing Chen et al. · European Heart Journal
Open access |
21 Jun 2025 |
19 |
| 14 |
Diagnostic classification of coronavirus disease 2019 (COVID-19) and other pneumonias using radiomics features in CT chest images
Ning Yang, Faming Liu, Chunlong Li et al. · Scientific Reports
Open access |
9 Sep 2021 |
19 |
| 15 |
Visualizing hepatitis B virus with biarsenical labelling in living cells
Shuzhen Sun, Jingjun Yan, Chao Xia et al. · Liver International
|
29 Nov 2013 |
15 |
| 16 |
Why thromboembolism occurs in some patients with thrombocytopenia and treatment strategies
Xiaorong Han, Cheng Li, Shuai Zhang et al. · Thrombosis Research
|
8 Oct 2020 |
14 |
| 17 |
β‑ecdysterone protects against apoptosis by promoting autophagy in nucleus pulposus cells and ameliorates disc degeneration
Feng Wen, Jun Yu, Cheng‐Jian He et al. · Molecular Medicine Reports
Open access |
15 Jan 2019 |
14 |
| 18 |
Coronary artery calcification and risk of mortality and adverse outcomes in patients with COVID-19: a Chinese multicenter retrospective cohort study
Song Jiao Luo et al. · Chinese Journal of Academic Radiology
Open access |
28 Jun 2021 |
13 |
| 19 |
The interaction between PDCD4 and YB1 is critical for cervical cancer stemness and cisplatin resistance
Dan Liu, Jing Ke, Yang Liu et al. · Molecular Carcinogenesis
|
9 Sep 2021 |
12 |
| 20 |
Changes in the Clinical Characteristics of 62 Patients Who Died from Coronavirus Disease 2019
Jingli Chen, Jishi Ye, Hui Li et al. · BioMed Research International
Open access |
2020 |
12 |
| 21 |
Lower body mass index and higher height are correlated with increased varicocele risk
Yuxuan Song, Yawei Xu, Zhen Chang Liang et al. · Andrologia
Open access |
2 Sep 2019 |
10 |
| 22 |
Blebbistatin modulates prostatic cell growth and contrapctility through myosin II signaling
Ping Chen, Deqiang Xu, Shengli Xu et al. · Clinical Science
|
2 Oct 2018 |
10 |
| 23 |
The effect of miR-138 on the proliferation and apoptosis of breast cancer cells through the NF-κB/VEGF signaling pathway
Hongbing Cheng, Liangji Chen, Zhenyu Fang et al. · Cellular and Molecular Biology
Open access |
28 Feb 2022 |
9 |
| 24 |
COVID‐19 infection in patients with connective tissue disease: A multicity study in Hubei province, China
Cong Ye et al. · MedComm
Open access |
4 Feb 2021 |
8 |
| 25 |
Expression and clinical significance of OPN and COX-2 in osteosarcoma
Youqiao Liao, Feng Li, Xiaogang Hu · The Chinese-German Journal of Clinical Oncology
|
Aug 2007 |
8 |
| 26 |
Clinical features of critically ill patients infected with SARS-CoV-2 outside Wuhan with and without diabetes
Xiaojuan Peng, Yanfang Chen, Liangfei Deng et al. · International Journal of Diabetes in Developing Countries
Open access |
Oct 2020 |
7 |
| 27 |
Enhance the Antimycobacterial Activity of Streptomycin with Ebselen as an Antibiotic Adjuvant Through Disrupting Redox Homeostasis
Chuanjiang Dong, Yueqing Wang, Yi Cai et al. · Drug Design Development and Therapy
Open access |
Aug 2024 |
6 |
| 28 |
Patient-Controlled Subcutaneous Analgesia with Hydromorphone versus Oral Oxycontin for Opioid Titration of Cancer Pain: A Prospective Multicenter Randomized Trial
Xiaoguang Xiao, Jianhai Sun, Dongsheng Zhang et al. · Journal of Pain Research
Open access |
Apr 2024 |
6 |
| 29 |
Successful Treatment of SAPHO Syndrome Complicated with Ankylosing Spondylitis by Secukinumab: A Case Report
Wei Tu, Daan Nie, Yuxue Chen et al. · Journal of Personalized Medicine
Open access |
13 Mar 2023 |
6 |
| 30 |
Gastric Cancer Screening Methods: A Comparative Study of Two Scoring Methods
Weixing Zhang, Zhangzhi Li, Muhammad Safwan Akram et al. · Cancer Management and Research
Open access |
Jul 2021 |
6 |
| 31 |
Relationship between Fatty Liver and Pancreatitis
Jing Jia, Qingming Wu, Jiguang Kou et al. · International Journal of Clinical Medicine
Open access |
2018 |
6 |
| 32 |
Therapeutic experience and key techniques of tubeless percutaneous nephrolithotomy
Yuanpeng Zhang, Xinwei Li, Genhua Yang et al. · Scientific Reports
Open access |
7 Jan 2025 |
5 |
| 33 |
Effectiveness of Xiaoyao capsule on sleep disorders and mood disturbance in patients in recovery from coronavirus disease 2019: a randomized controlled trial.
Yang Cunqing, Lian Fengmei, Yang Guiping et al. · PubMed
Open access |
Apr 2023 |
5 |
| 34 |
Ruminococcus bromii alleviates constipation by pullulanase-driven resistant starch degradation and microbiota modulation
Rong Li, Qianqian Yang, Jian He et al. · npj Biofilms and Microbiomes
Open access |
14 Dec 2025 |
4 |
| 35 |
The potential mechanism of HIF-1α and CD147 in the development of triple-negative breast cancer
Menghe Chen, Zitao Liu, Kai Zheng et al. · Medicine
Open access |
7 Jun 2024 |
4 |
| 36 |
Shengmaisan combined with Liuwei Dihuang Decoction alleviates chronic intermittent hypoxia-induced cognitive impairment by activating the EPO/EPOR/JAK2 signaling pathway
Jianchao Si, Xue Chen, Kerong Qi et al. · Chinese Journal of Natural Medicines
|
May 2024 |
4 |
| 37 |
Early diagnosis and prognostic potential of RAC3 in bladder tumor
Shuo Wang, Wei Zhuo, Hui‐Kuo G. Shu et al. · International Urology and Nephrology
Open access |
20 Sep 2023 |
4 |
| 38 |
Norwegian Scabies Mimicking Seborrheic Scalp Dermatitis in a Patient with Chronic Hepatitis C
Lv-Ya Zhang, Yu Xiao, Juanjuan Zou et al. · International Journal of Dermatology and Venereology
Open access |
5 Dec 2019 |
4 |
| 39 |
Surface-enhanced Raman spectroscopy for classification of laryngeal cancer and adjacent tissues
Haichun Lai, Zhengdong Wan, Qiong Wu et al. · Laser Physics
|
5 Sep 2019 |
4 |
| 40 |
High-performance Bi2WO6 nanoparticles for an integrated chip electrochemical dopamine sensor
Zhishan Liang, Yingming Ma, Yingning He et al. · Journal of Electroanalytical Chemistry
|
21 Jul 2025 |
3 |
| 41 |
A nonsynonymous polymorphism (rs117179004, T392M) of hyaluronidase 1 (HYAL1) is associated with increased risk of idiopathic pulmonary fibrosis in Southern Han Chinese
Juan Liu et al. · Journal of Clinical Laboratory Analysis
Open access |
4 May 2021 |
3 |
| 42 |
Substitution-degree-engineered acetylated curdlan Janus dressing: Unidirectional self-pumping for efficient wound exudate management and accelerated healing
Shaojing Yang, Shixiong Yang, Yixuan Cai et al. · Carbohydrate Polymers
|
18 Jan 2026 |
2 |
| 43 |
Beyond the Cell Atlas
Yiming Li, Tingkun Ma, Hao Lu et al. · Journal of the American Society of Nephrology
Open access |
9 Jan 2026 |
2 |
| 44 |
HOPX regulates the invasion and migration abilities of hepatocellular carcinoma by targeting SNAIL
Rong Wang, Haizhou Xu, Cheng‐Hu Hu et al. · Scientific Reports
Open access |
13 Aug 2025 |
2 |
| 45 |
Efficacy of Biofeedback Therapy on Chronic Constipation and Sexual Dysfunction in Postmenopausal Women: A Randomized Controlled Trial
Rong Wang, Xia Meng, Zhixiang Gao et al. · Neurogastroenterology & Motility
Open access |
20 May 2025 |
2 |
| 46 |
Enhanced the long-term impact of immunomodulatory treatment on the quality of life in patients suffering from allergic rhinitis
Jie Cai, Ping Tao, Ding Feng · Medicine
Open access |
25 Apr 2025 |
2 |
| 47 |
Single-cell RNA sequencing reveals the heterogeneity and regulatory modules of cell-specific RNA-binding proteins in patients with systemic lupus erythematosus
Sheng‐Yan Lin, Yikai Yu, Daan Nie et al. · Biochemistry and Biophysics Reports
Open access |
25 Mar 2025 |
2 |
| 48 |
Nanopore third-generation sequencing for the diagnosis of rare hemoglobinopathies in Southern China
Fen Lin, Shi-Xiong Yang, Yi-Yuan Ge et al. · Journal of Human Genetics
|
18 May 2026 |
1 |
| 49 |
Comparing the performance of four mainstream large language models on medical literature review generation: a human expert evaluation in SMILE surgery
Mengyun Zhou, Fu Gui, Chong Ai et al. · Graefe s Archive for Clinical and Experimental Ophthalmology
Open access |
3 Jan 2026 |
1 |
| 50 |
Case Report: Treatment of chondroblastoma of the first metatarsal bone in children with the induced membrane technique
Zonghuan Li, Zheng Wang, Hong Liu et al. · Frontiers in Pediatrics
Open access |
4 Dec 2025 |
1 |