Most cited papers from Yakult Central Institute

Yakult Central Institute

What are the most cited papers from Yakult Central Institute?

The most cited paper from Yakult Central Institute is "Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria" (Ivaylo I. Ivanov, Koji Atarashi, Nicolas Manel et al., 2009), with 4,598 citations. Next come "Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species" (3,724) and "Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells" (1,585).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 245 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria Ivaylo I. Ivanov, Koji Atarashi, Nicolas Manel et al. · Cell Open access	Oct 2009	4,598
2	Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species Koji Atarashi, Takeshi Tanoue, Tatsuichiro Shima et al. · Science Open access	23 Dec 2010	3,724
3	Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells Hsin-Jung Joyce Wu, Ivaylo I. Ivanov, Jaime R. Darce et al. · Immunity Open access	Jun 2010	1,585
4	Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis Yun Kyung Lee, Juscilene S. Menezes, Yoshinori Umesaki et al. · Proceedings of the National Academy of Sciences Open access	26 Jul 2010	1,334
5	Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota Hachung Chung, Sünje Johanna Pamp, Jonathan A. Hill et al. · Cell Open access	Jun 2012	1,252
6	Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells Koji Atarashi et al. · Cell Open access	24 Sep 2015	1,099
7	ATP drives lamina propria TH17 cell differentiation Koji Atarashi, Junichi Nishimura, Tatsuichiro Shima et al. · Nature	20 Aug 2008	1,092
8	Gender Bias in Autoimmunity Is Influenced by Microbiota Leonid Yurkovetskiy, Michael P. Burrows, Aly Azeem Khan et al. · Immunity Open access	Aug 2013	947
9	Development of 16S rRNA-Gene-Targeted Group-Specific Primers for the Detection and Identification of Predominant Bacteria in Human Feces Takahiro Matsuki, Koichi Watanabe, Junji Fujimoto et al. · Applied and Environmental Microbiology Open access	Nov 2002	663
10	Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors Takashi Sakata · British Journal Of Nutrition Open access	Jul 1987	658
11	Use of 16S rRNA Gene-Targeted Group-Specific Primers for Real-Time PCR Analysis of Predominant Bacteria in Human Feces Takahiro Matsuki, Koichi Watanabe, Junji Fujimoto et al. · Applied and Environmental Microbiology Open access	Dec 2004	658
12	Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder Emiko Aizawa, Hirokazu Tsuji, Takashi Asahara et al. · Journal of Affective Disorders	24 May 2016	589
13	Innate lymphoid cells regulate intestinal epithelial cell glycosylation Yoshiyuki Goto et al. · Science Open access	21 Aug 2014	576
14	Blood-pressure-lowering effect of a novel fermented milk containing γ-aminobutyric acid (GABA) in mild hypertensives Kiyoshi Inoue, Tsuyoshi Shirai, Hisao Ochiai et al. · European Journal of Clinical Nutrition	Mar 2003	548
15	Intestinal Dysbiosis and Lowered Serum Lipopolysaccharide-Binding Protein in Parkinson’s Disease Satoru Hasegawa, Sae Goto, Hirokazu Tsuji et al. · PLoS ONE Open access	5 Nov 2015	539
16	Quantitative PCR with 16S rRNA-Gene-Targeted Species-Specific Primers for Analysis of Human Intestinal Bifidobacteria Takahiro Matsuki, Koichi Watanabe, Junji Fujimoto et al. · Applied and Environmental Microbiology Open access	2004	506
17	Cis3/Socs3/Ssi3 Plays a Negative Regulatory Role in Stat3 Activation and Intestinal Inflammation Asuka Suzuki, Toshikatsu Hanada, Keiichi Mitsuyama et al. · The Journal of Experimental Medicine Open access	12 Feb 2001	478
18	Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome Chie Tana, Yoshinori Umesaki, Akemi Imaoka et al. · Neurogastroenterology & Motility	Nov 2009	473
19	Distribution of Bifidobacterial Species in Human Intestinal Microflora Examined with 16S rRNA-Gene-Targeted Species-Specific Primers Takahiro Matsuki, Koichi Watanabe, Ryuichiro Tanaka et al. · Applied and Environmental Microbiology Open access	Oct 1999	457
20	Early-Life Events, Including Mode of Delivery and Type of Feeding, Siblings and Gender, Shape the Developing Gut Microbiota Rocı́o Martı́n, Hiroshi Makino, Aysun Cetinyurek‐Yavuz et al. · PLoS ONE Open access	30 Jun 2016	456
21	Gut Dysbiosis and Detection of “Live Gut Bacteria” in Blood of Japanese Patients With Type 2 Diabetes Junko Sato et al. · Diabetes Care	14 May 2014	455
22	The Polymeric Immunoglobulin Receptor Translocates Pneumococci across Human Nasopharyngeal Epithelial Cells Jing‐Ren Zhang, Keith E. Mostov, Michael E. Lamm et al. · Cell Open access	Sep 2000	423
23	Recent progress on research and applications of non-digestible galacto-oligosaccharides Tomoyuki Sako, Keisuke Matsumoto, Ryuichiro Tanaka · International Dairy Journal	1999	421
24	Randomized placebo‐controlled trial assessing the effect of bifidobacteria‐fermented milk on active ulcerative colitis Kimitoshi Kato, Shigeaki Mizuno, Yoshinori Umesaki et al. · Alimentary Pharmacology & Therapeutics	Nov 2004	398
25	A key genetic factor for fucosyllactose utilization affects infant gut microbiota development Takahiro Matsuki, Kana Yahagi, Hiroshi Mori et al. · Nature Communications Open access	24 Jun 2016	381
26	Randomized Controlled Trial of the Effect of Bifidobacteria-Fermented Milk on Ulcerative Colitis Hideki Ishikawa, Ikuko Akedo, Yoshinori Umesaki et al. · Journal of the American College of Nutrition	Feb 2003	369
27	Segmented Filamentous Bacteria Are Indigenous Intestinal Bacteria That Activate Intraepithelial Lymphocytes and Induce MHC Class II Molecules and Fucosyl Asialo GM1 Glycolipids on the Small Intestinal Epithelial Cells in the Ex‐Germ‐Free Mouse Yoshinori Umesaki, Yasushi Okada, Satoshi Matsumoto et al. · Microbiology and Immunology Open access	Aug 1995	353
28	Probiotic Bifidobacterium breve Induces IL-10-Producing Tr1 Cells in the Colon Seong Gyu Jeon, Hisako Kayama, Yoshiyasu Ueda et al. · PLoS Pathogens Open access	31 May 2012	350
29	Perioperative Synbiotic Treatment to Prevent Postoperative Infectious Complications in Biliary Cancer Surgery Gen Sugawara, Masato Nagino, Hideki Nishio et al. · Annals of Surgery Open access	20 Oct 2006	348
30	Key bacterial taxa and metabolic pathways affecting gut short-chain fatty acid profiles in early life Naoki Tsukuda, Kana Yahagi, Taeko Hara et al. · The ISME Journal Open access	15 Mar 2021	337
31	Effect of a γ-aminobutyric acid-enriched dairy product on the blood pressure of spontaneously hypertensive and normotensive Wistar–Kyoto rats Kazuhito Hayakawa, Masayuki Kimura, Keiko Kasaha et al. · British Journal Of Nutrition Open access	Sep 2004	332
32	Identification of phenol- and p-cresol-producing intestinal bacteria by using media supplemented with tyrosine and its metabolites Yuki Saito, Tadashi Sato, Koji Nomoto et al. · FEMS Microbiology Ecology Open access	21 Jun 2018	327
33	Gut dysbiosis is associated with metabolism and systemic inflammation in patients with ischemic stroke Kazuo Yamashiro, Ryota Tanaka, Takao Urabe et al. · PLoS ONE Open access	6 Feb 2017	327
34	Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease Hiromasa Takaishi, Takahiro Matsuki, Atsushi Nakazawa et al. · International Journal of Medical Microbiology	26 Sep 2007	326
35	Early administration of Bifidobacterium breve to preterm infants: randomised controlled trial Hiroyuki Kitajima, Yutaka Sumida, Ryuichiro Tanaka et al. · Archives of Disease in Childhood Fetal & Neonatal Open access	Mar 1997	320
36	Diversity in gut bacterial community of school-age children in Asia Jiro Nakayama et al. · Scientific Reports Open access	23 Feb 2015	311
37	Fucoidan induces apoptosis of human HS-Sultan cells accompanied by activation of caspase-3 and down-regulation of ERK Pathways Yoshinobu Aisa, Yoshitaka Miyakawa, Tomonori Nakazato et al. · American Journal of Hematology	2004	308
38	Mother-to-Infant Transmission of Intestinal Bifidobacterial Strains Has an Impact on the Early Development of Vaginally Delivered Infant's Microbiota Hiroshi Makino, Akira Kushiro, Eiji Ishikawa et al. · PLoS ONE Open access	14 Nov 2013	305
39	Description of Christensenella minuta gen. nov., sp. nov., isolated from human faeces, which forms a distinct branch in the order Clostridiales, and proposal of Christensenellaceae fam. nov. Masami Morotomi, Fumiko Nagai, Y. Watanabe · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY	25 Feb 2011	304
40	Sensitive Quantitative Detection of Commensal Bacteria by rRNA-Targeted Reverse Transcription-PCR Kazunori Matsuda, Hirokazu Tsuji, Takashi Asahara et al. · Applied and Environmental Microbiology Open access	26 Dec 2006	298
41	Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Noriko KANEDA, Hiroko Nagata, Tomio Furuta et al. · PubMed	15 Mar 1990	293
42	Modulating immune responses with probiotic bacteria Takeshi Matsuzaki, James Chin · Immunology and Cell Biology	Feb 2000	292
43	Gut Microbiota Drive Autoimmune Arthritis by Promoting Differentiation and Migration of Peyer’s Patch T Follicular Helper Cells Fei Teng, Christina N. Klinger, Krysta M. Felix et al. · Immunity Open access	Apr 2016	287
44	Lipoteichoic Acids fromLactobacillusStrains Elicit Strong Tumor Necrosis Factor Alpha-Inducing Activities in Macrophages through Toll-Like Receptor 2 Tetsuya Matsuguchi, Akimitsu Takagi, Takeshi Matsuzaki et al. · Clinical and Vaccine Immunology Open access	Mar 2003	286
45	Fermented Milk Containing Lactobacillus casei Strain Shirota Preserves the Diversity of the Gut Microbiota and Relieves Abdominal Dysfunction in Healthy Medical Students Exposed to Academic Stress Akito Kato-Kataoka, Kensei Nishida, Mai Takada et al. · Applied and Environmental Microbiology Open access	7 May 2016	285
46	Probiotic Bifidobacteria Protect Mice from Lethal Infection with Shiga Toxin-Producing Escherichia coli O157:H7 Takashi Asahara, Kensuke Shimizu, Koji Nomoto et al. · Infection and Immunity Open access	23 Mar 2004	277
47	Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain Satoshi Matsumoto, Yoshio Okabe, Hiromi Setoyama et al. · Gut Open access	Jul 1998	275
48	Expansion of alpha beta T-cell receptor-bearing intestinal intraepithelial lymphocytes after microbial colonization in germ-free mice and its independence from thymus. Yoshinori Umesaki, Hiromi Setoyama, Satoshi Matsumoto et al. · PubMed Open access	May 1993	275
49	Characterization of Phascolarctobacterium succinatutens sp. nov., an Asaccharolytic, Succinate-Utilizing Bacterium Isolated from Human Feces Y. Watanabe, Fumiko Nagai, Masami Morotomi · Applied and Environmental Microbiology Open access	12 Nov 2011	274
50	Differential Roles of Segmented Filamentous Bacteria and Clostridia in Development of the Intestinal Immune System Yoshinori Umesaki, Hiromi Setoyama, Satoshi Matsumoto et al. · Infection and Immunity Open access	Jul 1999	273

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.