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Institution · Zentrum für Kinderheilkunde

Most cited papers from Zentrum für Kinderheilkunde

Zentrum für Kinderheilkunde

What are the most cited papers from Zentrum für Kinderheilkunde?

The most cited paper from Zentrum für Kinderheilkunde is "Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks" (Javed Iqbal Khan, Jun Stephen Wei, Markus Ringnér et al., 2001), with 2,668 citations. Next come "Prognostic Factors in High-Grade Osteosarcoma of the Extremities or Trunk: An Analysis of 1,702 Patients Treated on Neoadjuvant Cooperative Osteosarcoma Study Group Protocols" (1,872) and "A gene (PEX) with homologies to endopeptidases is mutated in patients with X–linked hypophosphatemic rickets" (1,118).

Showing 50 of 60 papers. Every paper with more than 136 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks Javed Iqbal Khan, Jun Stephen Wei, Markus Ringnér et al. · Nature Medicine Open access Jun 2001 2,668
2 Prognostic Factors in High-Grade Osteosarcoma of the Extremities or Trunk: An Analysis of 1,702 Patients Treated on Neoadjuvant Cooperative Osteosarcoma Study Group Protocols Stefan S. Bielack, Beate Kempf‐Bielack, G. Delling et al. · Journal of Clinical Oncology Feb 2002 1,872
3 A gene (PEX) with homologies to endopeptidases is mutated in patients with X–linked hypophosphatemic rickets Fiona Francis et al. · Nature Genetics Oct 1995 1,118
4 A Randomized, Controlled Trial of Oral Propranolol in Infantile Hemangioma Christine Léauté-Labrèze et al. · New England Journal of Medicine Open access 18 Feb 2015 804
5 Detectable clonal mosaicism and its relationship to aging and cancer Kevin B. Jacobs et al. · Nature Genetics Open access189 authors 6 May 2012 605
6 Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference Adrianna Vlachos, Sarah E. Ball, Niklas Dahl et al. · British Journal of Haematology Open access 30 Jul 2008 477
7 Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused byRASA1 mutations Nicole Revençu et al. · Human Mutation Open access 2008 437
8 Carbohydrate-deficient glycoprotein syndrome type Ib. Phosphomannose isomerase deficiency and mannose therapy. Reinhard Niehues, Martin Hasilik, Gordon Alton et al. · Journal of Clinical Investigation Open access Apr 1998 431
9 Treatment of autoinflammatory diseases: results from the Eurofever Registry and a literature review Nienke M. ter Haar et al. · Annals of the Rheumatic Diseases Open access 29 Jun 2012 425
10 Comparing the German Versions of the Strengths and Difficulties Questionnaire (SDQ-Deu) and the Child Behavior Checklist Henrikje Klasen, Wolfgang Woerner, Dieter Wolke et al. · European Child & Adolescent Psychiatry 20 Oct 2000 415
11 Factors influencing age at diagnosis of primary ciliary dyskinesia in European children Claudia Elisabeth Kuehni, Th. Frischer, Marie‐Pierre F. Strippoli et al. · European Respiratory Journal Open access 7 Jun 2010 376
12 Clinical Course and the Role of Shiga Toxin–Producing Escherichia coli Infection in the Hemolytic‐Uremic Syndrome in Pediatric Patients, 1997–2000, in Germany and Austria: A Prospective Study Angela Gerber, Helge Karch, Franz J. Allerberger et al. · The Journal of Infectious Diseases Open access 15 Aug 2002 365
13 Long-term results of the co-operative German–Austrian–Swiss osteosarcoma study group’s protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs Nicola Fuchs, Stefan S. Bielack, D. Epler et al. · Annals of Oncology Open access Aug 1998 349
14 Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency Torben Lübke, Thorsten Marquardt, Amos Etzioni et al. · Nature Genetics Open access May 2001 344
15 Mutant G-protein-coupled receptors as a cause of human diseases Torsten Schöneberg, Angela Martina Schulz, Heike Biebermann et al. · Pharmacology & Therapeutics 12 Oct 2004 339
16 Regional Age Dependence of Human Brain Metabolites from Infancy to Adulthood as Detected by Quantitative Localized Proton MRS Petra J. W. Pouwels, Knut Brockmann, Bernd Kruse et al. · Pediatric Research Oct 1999 316
17 The development of the macronucleus in the ciliated protozoan Stylonychia mytilus Dieter Ammermann, G. Steinbrück, von Berger L et al. · Chromosoma Dec 1974 315
18 Congenital disorders of glycosylation: review of their molecular bases, clinical presentations and specific therapies Thorsten Marquardt, Jonas Denecke · European Journal of Pediatrics 15 Mar 2003 294
19 Cystathionine ?-synthase mutations in homocystinuria Jan Peter Kraus, Miroslav Jano �k, Viktor Ko ich et al. · Human Mutation 1999 281
20 Evidence-based provisional clinical classification criteria for autoinflammatory periodic fevers Silvia Federici et al. · Annals of the Rheumatic Diseases 31 Jan 2015 270
21 Distinct spectrum of CFTR gene mutations in congenital absence of vas deferens Thilo Dörk, Bernd Dworniczak, C. Aulehla‐Scholz et al. · Human Genetics 4 Aug 1997 257
22 Rett syndrome: analysis of MECP2 and clinical characterization of 31 patients Peter Huppke · Human Molecular Genetics 22 May 2000 246
23 Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study Samantha Claudia Gouw, Johanna G. van der Bom, Günter Auerswald et al. · Blood 12 Jan 2007 239
24 Second and Subsequent Recurrences of Osteosarcoma: Presentation, Treatment, and Outcomes of 249 Consecutive Cooperative Osteosarcoma Study Group Patients Stefan S. Bielack, Beate Kempf‐Bielack, Detlev Branscheid et al. · Journal of Clinical Oncology 15 Dec 2008 237
25 Mutations in FAM20C Are Associated with Lethal Osteosclerotic Bone Dysplasia (Raine Syndrome), Highlighting a Crucial Molecule in Bone Development Michael A. Simpson, Ray C. J. Hsu, Lindsay S. Keir et al. · The American Journal of Human Genetics Open access 19 Oct 2007 229
26 Increase of total creatine in human brain after oral supplementation of creatine-monohydrate Peter Dechent, Petra J. W. Pouwels, Bethany F. Wilken et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology Sep 1999 226
27 The transcription factor Prox1 is a marker for lymphatic endothelial cells in normal and diseased human tissues Jörg Wilting, Maria Papoutsi, Bodo Christ et al. · The FASEB Journal 7 Jun 2002 226
28 Clinical and prognostic relevance of the Kiel classification of non‐Hodgkin lymphomas results of a prospective multicenter study by the Kiel Lymphoma Study Group Guenter Brittinger et al. · Hematological Oncology Jul 1984 209
29 Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations Martin Zenker, Katarina Lehmann, AL Schulz et al. · Journal of Medical Genetics Open access 20 Oct 2006 203
30 Types of Study in Medical Research Bernd Röhrig, Jean‐Baptist du Prel, Daniel Wachtlin et al. · Deutsches Ärzteblatt international Open access 10 Apr 2009 196
31 Chemotherapy versus allogeneic transplantation for very-high-risk childhood acute lymphoblastic leukaemia in first complete remission: comparison by genetic randomisation in an international prospective study Adriana Balduzzi, Maria Grazia Valsecchi, CORNELIO UDERZO et al. · The Lancet Aug 2005 195
32 Autosomal recessive polycystic kidney disease in 115 children: clinical presentation, course and influence of gender Klaus Zerres, Sabine Rudnik‐Schöneborn, Felicitas Deget et al. · Acta Paediatrica Apr 1996 185
33 Prediction of Clinical Outcome Using Gene Expression Profiling and Artificial Neural Networks for Patients with Neuroblastoma Jun Stephen Wei, Braden T. Greer, Frank Westermann et al. · Cancer Research Open access Oct 2004 184
34 Combination of omalizumab and specific immunotherapy is superior to immunotherapy in patients with seasonal allergic rhinoconjunctivitis and co‐morbid seasonal allergic asthma Matthias Kopp, Eckard H. Hamelmann, Stefan Zielen et al. · Clinical & Experimental Allergy 10 Nov 2008 184
35 Guideline for the management of myasthenic syndromes Heinz Wiendl et al. · Therapeutic Advances in Neurological Disorders Open access 2023 182
36 Diffuse White Matter Disease in Three Children: An Encephalopathy with Unique Features on Magnetic Resonance Imaging and Proton Magnetic Resonance Spectroscopy Folker A. Hanefeld, Ulrike Holzbach, B. Kruse et al. · Neuropediatrics Oct 1993 181
37 S2k-Leitlinie: Nichtinvasive und invasive Beatmung als Therapie der chronischen respiratorischen Insuffizienz – Revision 2017 W. Windisch et al. · Pneumologie Nov 2017 180
38 Normative values of polysomnographic parameters in childhood and adolescence: Quantitative sleep parameters Sabine Scholle, Uta Beyer, Michael Bernhard et al. · Sleep Medicine 23 May 2011 175
39 Goitre epidemiology: thyroid volume, iodine excretion, thyroglobulin and thyrotropin in Germany and Sweden R. Gutekunst, H. Smolarek, U. Hasenpusch et al. · European Journal of Endocrinology Aug 1986 174
40 Pediatric acute myeloid leukemia: international progress and future directions Gertjan J.L. Kaspers, Ursula Creutzig · Leukemia Open access 22 Nov 2005 172
41 Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site Jürgen Braunger, Lothar Schleithoff, Ansgar Schulz et al. · Oncogene 5 Jun 1997 170
42 Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study Patrick Linsel‐Nitschke et al. · PLoS ONE Open access 19 Aug 2008 170
43 A Common Mutation Is Associated with a Mild, Potentially Asymptomatic Phenotype in Patients with Isovaleric Acidemia Diagnosed by Newborn Screening Regina E. Ensenauer, Jerry E. Vockley, Jan-Marie Willard et al. · The American Journal of Human Genetics Open access 3 Nov 2004 168
44 Tumor necrosis factor-alpha blocker in treatment of juvenile idiopathic arthritis-associated uveitis refractory to second-line agents: results of a multinational survey. Ivan Foeldvari, Susanne Dam Nielsen, Jasmin Beate Kümmerle-Deschner et al. · PubMed May 2007 167
45 Autosomal-Dominant Mode of Inheritance of a Melanocortin-4 Receptor Mutation in a Patient with Severe Early-Onset Obesity Is Due to a Dominant-Negative Effect Caused by Receptor Dimerization Heike Biebermann, Heiko Krude, Andrea Elsner et al. · Diabetes Dec 2003 167
46 Safety, tolerability, and immunologic noninferiority of a 13-valent pneumococcal conjugate vaccine compared to a 7-valent pneumococcal conjugate vaccine given with routine pediatric vaccinations in Germany Dorothee M. Kieninger, Kathrin Kueper, Katrin Steul et al. · Vaccine 23 Apr 2010 167
47 Localization of the gene encoding the α2/δ-subunits of the L-type voltage-dependent calcium channel to chromosome 7q and analysis of the segregation of flanking markers in malignant hyperthermia susceptible families David Iles, F. Lehmann‐Horn, Stephen W. Scherer et al. · Human Molecular Genetics 1994 166
48 Spectrum of mutations in PTPN11 and genotype–phenotype correlation in 96 patients with Noonan syndrome and five patients with cardio-facio-cutaneous syndrome Luciana Musante, Hans-Gerd Kehl, Frank Majewski et al. · European Journal of Human Genetics Feb 2003 164
49 Genomic Organization of the Human PEX Gene Mutated in X-Linked Dominant Hypophosphatemic Rickets Fiona Francis, Tim Matthias Strom, Steffen Hennig et al. · Genome Research Open access Jun 1997 163
50 Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease Patrick Linsel‐Nitschke et al. · Atherosclerosis 9 Jul 2009 163

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.