| 1 |
Frailty syndrome: an overview
Sean Xiao Leng, Xujiao Chen, Genxiang Mao · Clinical Interventions in Aging
Open access |
Mar 2014 |
1,006 |
| 2 |
Role of pyroptosis in inflammation and cancer
Wei Xiang, Feng Xie, Xiaoxue Zhou et al. · Cellular and Molecular Immunology
Open access |
15 Aug 2022 |
708 |
| 3 |
WEGO 2.0: a web tool for analyzing and plotting GO annotations, 2018 update
Jia Ye, Yong Zhang, Huihai Cui et al. · Nucleic Acids Research
Open access |
10 May 2018 |
671 |
| 4 |
SARS-CoV-2 Omicron variant: recent progress and future perspectives
Yao Fan, Xiang Li, Lei Zhang et al. · Signal Transduction and Targeted Therapy
Open access |
28 Apr 2022 |
639 |
| 5 |
An overview of COVID-19
Yu Shi, Gang Wang, Xiao-peng Cai et al. · Journal of Zhejiang University SCIENCE B
Open access |
May 2020 |
599 |
| 6 |
Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics
Yinghong Li, Chun Yan Yu, Xiao Xu Li et al. · Nucleic Acids Research
Open access |
10 Nov 2017 |
556 |
| 7 |
Psychological stress of ICU nurses in the time of COVID-19
Xin Shen, Xiaoyue Zou, Xiaofeng Zhong et al. · Critical Care
Open access |
6 May 2020 |
503 |
| 8 |
Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity
Bing Liu, Liyan Qu, Shigui Yan · Cancer Cell International
Open access |
5 Nov 2015 |
418 |
| 9 |
Accurate leukocyte detection based on deformable-DETR and multi-level feature fusion for aiding diagnosis of blood diseases
Yifei Chen, Chenyan Zhang, Ben Chen et al. · Computers in Biology and Medicine
|
5 Jan 2024 |
415 |
| 10 |
Study of cardiovascular disease prediction model based on random forest in eastern China
Yang Li, Haibin Wu, Xiaoqing Jin et al. · Scientific Reports
Open access |
23 Mar 2020 |
360 |
| 11 |
HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma
Qiuran Xu, Jian‐Feng Tu, Changwei Dou et al. · Molecular Cancer
Open access |
Dec 2017 |
316 |
| 12 |
Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information
Hong Jun Yang, Qin Chu, Yinghong Li et al. · Nucleic Acids Research
Open access |
17 Nov 2015 |
286 |
| 13 |
NPASS: natural product activity and species source database for natural product research, discovery and tool development
Xian Liang Zeng, Peng Zhang, Weidong He et al. · Nucleic Acids Research
Open access |
18 Oct 2017 |
284 |
| 14 |
Repair of tooth enamel by a biomimetic mineralization frontier ensuring epitaxial growth
Changyu Shao, Biao Jin, 昭 高木 et al. · Science Advances
Open access |
2 Aug 2019 |
278 |
| 15 |
Intensive blood pressure control after endovascular thrombectomy for acute ischaemic stroke (ENCHANTED2/MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial
Pengfei Yang et al. · The Lancet
Open access |
28 Oct 2022 |
264 |
| 16 |
Intradialytic Exercise in Hemodialysis Patients: A Systematic Review and Meta-Analysis
Kaixiang Sheng, Ping Zhang, Lili Chen et al. · American Journal of Nephrology
Review |
2014 |
259 |
| 17 |
Opportunistic Screening Using Low-Dose CT and the Prevalence of Osteoporosis in China: A Nationwide, Multicenter Study
Xiaoguang Cheng et al. · Journal of Bone and Mineral Research
Open access |
4 Nov 2020 |
242 |
| 18 |
MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion
Hui‐Ju Wang, Hong-jun Ruan, Xujun He et al. · European Journal of Cancer
|
9 Jun 2010 |
242 |
| 19 |
Therapeutic effect of forest bathing on human hypertension in the elderly
Genxiang Mao, Yong-Bao Cao, Xiao-Guang Lan et al. · Journal of Cardiology
Open access |
Sep 2012 |
237 |
| 20 |
Berberine diminishes cancer cell PD-L1 expression and facilitates antitumor immunity via inhibiting the deubiquitination activity of CSN5
Yang Liu, Xiaojia Liu, Na Zhang et al. · Acta Pharmaceutica Sinica B
Open access |
30 Jun 2020 |
236 |
| 21 |
miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc
Zhe Chen, Huazong Zeng, Yong Guo et al. · Journal of Experimental & Clinical Cancer Research
Open access |
22 Nov 2010 |
232 |
| 22 |
Ferrimagnetic Vortex Nanoring-Mediated Mild Magnetic Hyperthermia Imparts Potent Immunological Effect for Treating Cancer Metastasis
Xiaoli Liu, Jianjun Zheng, Wei Yan Sun et al. · ACS Nano
|
22 Jul 2019 |
231 |
| 23 |
LncRNAs regulate metabolism in cancer
Wenyu Lin, Qiyin Zhou, Chaoqun Wang et al. · International Journal of Biological Sciences
Open access |
2020 |
229 |
| 24 |
Guidelines for the diagnosis and management of alcoholic liver disease: Update 2010
You Ming Li, Jian‐Gao Fan, Bing Yuan Wang et al. · Journal of Digestive Diseases
Open access |
18 Nov 2010 |
223 |
| 25 |
Different treatment strategies and molecular features between right-sided and left-sided colon cancers
Hong Shen · World Journal of Gastroenterology
Open access |
2015 |
222 |
| 26 |
Single‐subject morphological brain networks: connectivity mapping, topological characterization and test–retest reliability
Hao Wang, Xiaoqing Jin, Ye Zhang et al. · Brain and Behavior
Open access |
3 Mar 2016 |
219 |
| 27 |
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism
Jing Du, Xu Wang, Yanchun Li et al. · Cell Death and Disease
Open access |
14 Jul 2021 |
218 |
| 28 |
The impact of Helicobacter pylori infection, eradication therapy and probiotic supplementation on gut microenvironment homeostasis: An open-label, randomized clinical trial
Luyi Chen, Wenli Xu, Allen A. Lee et al. · EBioMedicine
Open access |
23 Aug 2018 |
217 |
| 29 |
Ultra-efficient Antibacterial System Based on Photodynamic Therapy and CO Gas Therapy for Synergistic Antibacterial and Ablation Biofilms
Wei Ma, Xiaoyi Chen, Luo‐Qin Fu et al. · ACS Applied Materials & Interfaces
|
24 Apr 2020 |
196 |
| 30 |
Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation
Dongsheng Huang et al. · European Journal of Cancer
Open access |
5 Apr 2015 |
195 |
| 31 |
Class Weights Random Forest Algorithm for Processing Class Imbalanced Medical Data
Min Zhu, Jing Xia, Xiaoqing Jin et al. · IEEE Access
Open access |
2018 |
192 |
| 32 |
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages
Yunlong Yang et al. · Nature Communications
Open access |
6 May 2016 |
192 |
| 33 |
MicroRNA‐183 regulates Ezrin expression in lung cancer cells
Guofu Wang, Weimin Mao, Shu Sen Zheng · FEBS Letters
|
7 Oct 2008 |
191 |
| 34 |
Corticosteroid treatment in severe COVID-19 patients with acute respiratory distress syndrome
Jiao Liu, Sheng Zhang, Xuan Dong et al. · Journal of Clinical Investigation
Open access |
2 Nov 2020 |
188 |
| 35 |
Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice
Jiawen Yu, Yaping Deng, Xue Han et al. · Cardiovascular Diabetology
Open access |
18 Jun 2016 |
184 |
| 36 |
LncRNA-MALAT1 contributes to the cisplatin-resistance of lung cancer by upregulating MRP1 and MDR1 via STAT3 activation
Zhixian Fang, Wenyu Chen, Zuguo Yuan et al. · Biomedicine & Pharmacotherapy
|
22 Mar 2018 |
177 |
| 37 |
Platelet-to-lymphocyte ratio as a prognostic predictor of mortality for sepsis: interaction effect with disease severity—a retrospective study
Yanfei Shen, Xinmei Huang, Weimin Zhang · BMJ Open
Open access |
2019 |
174 |
| 38 |
MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway
Qiuran Xu, Xin Liu, Zhikui Liu et al. · Molecular Cancer
Open access |
12 Jun 2017 |
173 |
| 39 |
Porous Pt Nanospheres Incorporated with GOx to Enable Synergistic Oxygen‐Inductive Starvation/Electrodynamic Tumor Therapy
Zijie Lu, Jiayu Gao, Chao Fang et al. · Advanced Science
Open access |
6 Jul 2020 |
167 |
| 40 |
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis
Yunben Yang, Lili Li, Chunjing Xu et al. · Gut
Open access |
29 Oct 2020 |
164 |
| 41 |
Fractional Flow Reserve or Intravascular Ultrasonography to Guide PCI
Bon‐Kwon Koo et al. · New England Journal of Medicine
Open access |
31 Aug 2022 |
158 |
| 42 |
Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Jing Liu et al. · Journal of Visualized Experiments
|
6 Mar 2019 |
153 |
| 43 |
Astragaloside IV, a Novel Antioxidant, Prevents Glucose-Induced Podocyte Apoptosis In Vitro and In Vivo
Dingkun Gui, Yongping Guo, Feng Wang et al. · PLoS ONE
Open access |
22 Jun 2012 |
153 |
| 44 |
Mechanisms involved in breast cancer liver metastasis
Rui Ma, Yi-Li Feng, Shuang Lin et al. · Journal of Translational Medicine
Open access |
15 Feb 2015 |
152 |
| 45 |
3D Printing of Physical Organ Models: Recent Developments and Challenges
Zhongboyu Jin, Yuanrong Li, Kang Yu et al. · Advanced Science
Open access |
8 Jul 2021 |
151 |
| 46 |
Association between triglyceride-glucose index and in-hospital mortality in critically ill patients with sepsis: analysis of the MIMIC-IV database
Rui Zheng, Songzan Qian, Yiyi Shi et al. · Cardiovascular Diabetology
Open access |
8 Nov 2023 |
146 |
| 47 |
A novel method for diabetes diagnosis based on electronic nose
Ping Wang, Tan Yi, Xie Haibao et al. · Biosensors and Bioelectronics
|
Nov 1997 |
146 |
| 48 |
Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression
Dingkun Gui, Jianhua Huang, Yongping Guo et al. · Cytokine
|
20 Feb 2013 |
144 |
| 49 |
Effects of a specially designed aerobic dance routine on mild cognitive impairment
Yi Zhu, Han Wu, Ming Qi et al. · Clinical Interventions in Aging
Open access |
Sep 2018 |
142 |
| 50 |
Ginsenoside Rg3 promotes cytotoxicity of Paclitaxel through inhibiting NF-κB signaling and regulating Bax/Bcl-2 expression on triple-negative breast cancer
Zuguo Yuan, Hao Jiang, Xinhai Zhu et al. · Biomedicine & Pharmacotherapy
|
20 Feb 2017 |
139 |