Science Explorer Back to mapMap

Most cited papers from Zogenix (United States)

What are the most cited papers from Zogenix (United States)?

The most cited paper from Zogenix (United States) is "Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial" (Lieven G. Lagae, Joseph E. Sullivan, Kelly G. Knupp et al., 2019), with 381 citations. Next come "Fenfluramine for Treatment-Resistant Seizures in Patients With Dravet Syndrome Receiving Stiripentol-Inclusive Regimens" (251) and "Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome" (136).

Showing 50 of 59 papers. Every paper with more than 10 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial Lieven G. Lagae, Joseph E. Sullivan, Kelly G. Knupp et al. · The Lancet Open access Dec 2019 381
2 Fenfluramine for Treatment-Resistant Seizures in Patients With Dravet Syndrome Receiving Stiripentol-Inclusive Regimens Rima Nabbout, Arun Mistry, Sameer M. Zuberi et al. · JAMA Neurology Open access 2 Dec 2019 251
3 Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome Kelly G. Knupp, Ingrid Eileen Scheffer, Berten Ceulemans et al. · JAMA Neurology Open access 2 May 2022 136
4 Bioinspired Design Provides High‐Strength Benzoxazine Structural Adhesives Cody James Higginson, Katerina G. Malollari, Yunqi Xu et al. · Angewandte Chemie International Edition Open access 5 Jul 2019 134
5 Low‐dose fenfluramine significantly reduces seizure frequency in Dravet syndrome: a prospective study of a new cohort of patients An‐Sofie Schoonjans, Bernard P. Paelinck, Fabienne Marchau et al. · European Journal of Neurology Open access 28 Oct 2016 107
6 Fenfluramine acts as a positive modulator of sigma-1 receptors Parthena Martin, Peter A.M. de Witte, Tangui Maurice et al. · Epilepsy & Behavior Open access 10 Mar 2020 99
7 Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome Judith Helen Cross, Bradley S. Galer, António Gil‐Nagel et al. · Seizure Open access 2 Nov 2021 85
8 A pilot, open‐label study of the effectiveness and tolerability of low‐dose ZX 008 (fenfluramine HC l) in Lennox‐Gastaut syndrome Lieven G. Lagae, An‐Sofie Schoonjans, Arnold R. Gammaitoni et al. · Epilepsia Open access 26 Aug 2018 71
9 Life impact of caregiving for severe childhood epilepsy: Results of expert panels and caregiver focus groups Mark P. Jensen, Kendra S. Liljenquist, Fraser D. Bocell et al. · Epilepsy & Behavior 20 Jul 2017 71
10 Fenfluramine HCl (Fintepla®) provides long‐term clinically meaningful reduction in seizure frequency: Analysis of an ongoing open‐label extension study Joseph E. Sullivan, Ingrid Eileen Scheffer, Lieven G. Lagae et al. · Epilepsia Open access 19 Oct 2020 69
11 Assessing the impact of caring for a child with Dravet syndrome: Results of a caregiver survey Jonathan D. Campbell, Melanie D. Whittington, Chong Kim et al. · Epilepsy & Behavior Open access 2 Feb 2018 68
12 Porting the synthetic D‐glucaric acid pathway from Escherichia coli to Saccharomyces cerevisiae Amita Gupta, Michael A. Hicks, Shawn P. Manchester et al. · Biotechnology Journal Open access 17 Jun 2016 68
13 A randomized controlled trial of ganaxolone in posttraumatic stress disorder Ann M. Rasmusson, Christine E. Marx, Sonia Jain et al. · Psychopharmacology 30 Jun 2017 67
14 A phase I, randomized, open-label, single-dose, 3-period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a regimen of stiripentol, clobazam, and valproate in healthy subjects Brooks Boyd, Steven M. Smith, Arnold R. Gammaitoni et al. · International Journal of Clinical Pharmacology and Therapeutics Open access 19 Oct 2018 64
15 Improved everyday executive functioning following profound reduction in seizure frequency with fenfluramine: Analysis from a phase 3 long-term extension study in children/young adults with Dravet syndrome Kim I. Bishop, Peter K. Isquith, Gérard A. Gioia et al. · Epilepsy & Behavior Open access 20 May 2021 61
16 The humanistic and economic burden of Dravet syndrome on caregivers and families: Implications for future research Mark P. Jensen, Andreas Brunklaus, Liam Dorris et al. · Epilepsy & Behavior 18 Apr 2017 60
17 An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies Parthena Martin, Thadd Reeder, Jo Sourbron et al. · International Journal of Molecular Sciences Open access 5 Aug 2021 55
18 convertibleCARs: A chimeric antigen receptor system for flexible control of activity and antigen targeting Kyle E. Landgraf, Steven R. Williams, Daniel Steiger et al. · Communications Biology Open access 9 Jun 2020 54
19 Fenfluramine provides clinically meaningful reduction in frequency of drop seizures in patients with Lennox–Gastaut syndrome: Interim analysis of an open‐label extension study Kelly G. Knupp, Ingrid Eileen Scheffer, Berten Ceulemans et al. · Epilepsia Open access 5 Oct 2022 53
20 Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo‐controlled clinical trial Joseph E. Sullivan, Lieven G. Lagae, Judith Helen Cross et al. · Epilepsia Open access 6 Aug 2023 52
21 Single-Entity Hydrocodone Extended-Release Capsules in Opioid-Tolerant Subjects with Moderate-to-Severe Chronic Low Back Pain: A Randomized Double-Blind, Placebo-Controlled Study Richard L Rauck, Srinivas R. Nalamachu, James E. Wild et al. · Pain Medicine 12 Feb 2014 52
22 Bidirectional C and N transfer and a potential role for sulfur in an epiphytic diazotrophic mutualism Rhona K. Stuart, Eric R. A. Pederson, Philip D. Weyman et al. · The ISME Journal Open access 19 Aug 2020 48
23 Cardiovascular safety of fenfluramine in the treatment of Dravet syndrome: Analysis of an ongoing long‐term open‐label safety extension study Wyman W. Lai, Bradley S. Galer, Pierre C. Wong et al. · Epilepsia Open access 18 Aug 2020 48
24 Needle‐Free Subcutaneous Sumatriptan (Sumavel™ DosePro™): Bioequivalence and Ease of Use Jan Lewis Brandes, Roger K. Cady, Fred G. Freitag et al. · Headache The Journal of Head and Face Pain 22 Oct 2009 47
25 An examination of the efficacy and safety of fenfluramine in adults, children, and adolescents with Dravet syndrome in a real‐world practice setting: A report from the Fenfluramine European Early Access Program Renzo Guerrini, Nicola Specchio, Ángel Aledo‐Serrano et al. · Epilepsia Open Open access 8 Jul 2022 45
26 Fenfluramine treatment is associated with improvement in everyday executive function in preschool-aged children (<5 years) with Dravet syndrome: A critical period for early neurodevelopment Kim I. Bishop, Peter K. Isquith, Gérard A. Gioia et al. · Epilepsy & Behavior Open access Dec 2022 44
27 The direct and indirect costs of Dravet Syndrome Melanie D. Whittington, Kelly G. Knupp, Gina R. VanderVeen et al. · Epilepsy & Behavior 2 Feb 2018 44
28 Cardiovascular safety of low-dose fenfluramine in Dravet syndrome: a review of its benefit-risk profile in a new patient population An‐Sofie Schoonjans, Fabienne Marchau, Bernard P. Paelinck et al. · Current Medical Research and Opinion Open access 13 Jul 2017 44
29 Communicating Structure and Function in Synthetic Biology Diagrams Jacob Beal et al. · ACS Synthetic Biology Open access 26 Jul 2019 43
30 A Mechanistic Study of Polyol Hydrodeoxygenation over a Bifunctional Pt-WOx/TiO2 Catalyst Kyle J. Stephens, Alan M. Allgeier, Alysha L. Bell et al. · ACS Catalysis 23 Oct 2020 42
31 Synthetic Biology Open Language (SBOL) Version 2.3 Curtis Madsen et al. · Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics Open access 13 Jun 2019 39
32 Fenfluramine significantly reduces day‐to‐day seizure burden by increasing number of seizure‐free days and time between seizures in patients with Dravet syndrome: A time‐to‐event analysis Joseph E. Sullivan, Nicola Specchio, Orrin Devinsky et al. · Epilepsia Open access 22 Oct 2021 38
33 Collaborating constructively for sustainable biotechnology Nicholas E. Matthews, Carrie A. Cizauskas, Donovan S. Layton et al. · Scientific Reports Open access 13 Dec 2019 38
34 Long-term cardiovascular safety of fenfluramine in patients with Dravet syndrome treated for up to 3 years: Findings from serial echocardiographic assessments Anupam Agarwal, Gail M. Farfel, Arnold R. Gammaitoni et al. · European Journal of Paediatric Neurology Open access 24 May 2022 30
35 Catalyzed reaction of isocyanates (RNCO) with water Mark E. Wolf, Jonathon E. Vandezande, Henry F. Schaefer · Physical Chemistry Chemical Physics 2021 30
36 Fenfluramine treatment for dravet syndrome: Real-world benefits on quality of life from the caregiver perspective Mark P. Jensen, Arnold R. Gammaitoni, Bradley S. Galer et al. · Epilepsy Research 7 Jul 2022 29
37 In vitro evaluation of fenfluramine and norfenfluramine as victims of drug interactions Parthena Martin, Maciej Czerwiński, Pallavi B. Limaye et al. · Pharmacology Research & Perspectives Open access 22 May 2022 23
38 In vitro evaluation suggests fenfluramine and norfenfluramine are unlikely to act as perpetrators of drug interactions Parthena Martin, Maciej Czerwiński, Pallavi B. Limaye et al. · Pharmacology Research & Perspectives Open access 22 May 2022 22
39 Psychosocial impact on siblings of patients with developmental and epileptic encephalopathies Laurie Bailey, Lauren Schwartz, Tracy Dixon‐Salazar et al. · Epilepsy & Behavior Open access 22 Aug 2020 22
40 Fenfluramine treatment for Dravet syndrome: Caregiver- and clinician-reported benefits on the quality of life of patients, caregivers, and families living in Germany, Spain, Italy, and the United Kingdom Mark P. Jensen, Arnold R. Gammaitoni, Rana Salem et al. · Epilepsy Research Open access 15 Jan 2023 21
41 Synthetic Biology Open Language Visual (SBOL Visual) Version 2.1 Curtis Madsen et al. · Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics Open access 13 Jun 2019 21
42 Satisfaction With and Confidence in Needle‐Free Subcutaneous Sumatriptan in Patients Currently Treated with Triptans Roger K. Cady, Sheena K. Aurora, Jan Lewis Brandes et al. · Headache The Journal of Head and Face Pain 3 Aug 2011 21
43 Treatment with fenfluramine in patients with Dravet syndrome has no long-term effects on weight and growth António Gil‐Nagel, Joseph E. Sullivan, Berten Ceulemans et al. · Epilepsy & Behavior Open access 2 Aug 2021 19
44 The Lack of Effect of Food on the Pharmacokinetics of ZX008 (Fenfluramine Oral Solution): Results of a Single-dose, Two-period Crossover Study Arnold R. Gammaitoni, Steven M. Smith, Brooks Boyd · Clinical Therapeutics Open access 22 Jun 2018 18
45 A real‐world study to assess the association of cardiovascular adverse events (CVAEs) with ibrutinib as first‐line (1L) treatment for patients with chronic lymphocytic leukaemia (CLL) in the United States Anthony R. Mato, Boxiong Tang, Soraya Azmi et al. · eJHaem Open access 23 Jan 2023 16
46 Fenfluramine modulates the anti-amnesic effects induced by sigma-1 receptor agonists and neuro(active)steroids in vivo Parthena Martin, Tangui Maurice, Arnold R. Gammaitoni et al. · Epilepsy & Behavior Open access 7 Jan 2022 16
47 A long-term, open-label safety study of single-entity hydrocodone bitartrate extended release for the treatment of moderate to severe chronic pain Srinivas R. Nalamachu, Richard L Rauck, Martin E Hale et al. · Journal of Pain Research Open access Nov 2014 16
48 The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life Dagmar Amtmann, Arnold R. Gammaitoni, Bradley S. Galer et al. · Mitochondrion 29 Oct 2022 15
49 Development and validation of the University of Washington caregiver stress and benefit scales for caregivers of children with or without serious health conditions Dagmar Amtmann, Kendra S. Liljenquist, Alyssa M. Bamer et al. · Quality of Life Research 4 Jan 2020 15
50 Influence of Sulfur‐Containing Diamino Acid Structure on Covalently Crosslinked Copolypeptide Hydrogels Eric D. Raftery, Eric G. Gharkhanian, Nicole G. Ricapito et al. · Chemistry - An Asian Journal Open access 17 Sep 2018 14

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.