Subfield · Biochemistry
Most cited papers in Biochemistry (Medicine)
What are the most cited papers in Biochemistry?
The most cited paper in Biochemistry is "Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues" (Haider Raza, Annie John, Abderrahim Nemmar, 2013), with 47,289 citations. Next come "Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction" (29,425) and "Antioxidant activity applying an improved ABTS radical cation decolorization assay" (26,207).
Showing 50 of 99 papers. Every paper with more than 2,361 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues Haider Raza, Annie John, Abderrahim Nemmar · Cellular Physiology and Biochemistry | 2013 | 47,289 |
| 2 | Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Hiroshi Ohkawa, Nobuko Ohishi, Kunio Yagi · Analytical Biochemistry | Jun 1979 | 29,425 |
| 3 | Antioxidant activity applying an improved ABTS radical cation decolorization assay Roberta Re, Nicoletta Pellegrini, Anna R. Proteggente et al. · Free Radical Biology and Medicine | May 1999 | 26,207 |
| 4 | Use of a free radical method to evaluate antioxidant activity Wendy Brand-Williams, Marie‐Elisabeth Cuvelier, Claudette Berset · LWT | 1995 | 25,846 |
| 5 | Free Radicals in the Physiological Control of Cell Function Wulf Dröge · Physiological Reviews | 2002 | 9,887 |
| 6 | Structure-antioxidant activity relationships of flavonoids and phenolic acids Catherine A Rice-Evans, Nicholas J. Miller, George Paganga · Free Radical Biology and Medicine | 1996 | 9,068 |
| 7 | Chlorophyll fluorescence—a practical guide Kate Maxwell, Giles N. Johnson · Journal of Experimental Botany | Apr 2000 | 8,881 |
| 8 | The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals Jia Zhishen, Tang Mengcheng, Jianming Wu · Food Chemistry | Mar 1999 | 8,838 |
| 9 | Polyphenols: food sources and bioavailability Claudine Manach, Augustin Scalbert, Christine Morand et al. · American Journal of Clinical Nutrition | May 2004 | 8,154 |
| 10 | Studies on products of browning reaction. Antioxidative activities of products of browning reaction prepared from glucosamine. Makoto Oyaizu · The Japanese Journal of Nutrition and Dietetics | 1986 | 7,717 |
| 11 | Determinations of total carotenoids and chlorophylls a and b of leaf extracts in different solvents Hartmut K. Lichtenthaler, Alan R. Wellburn · Biochemical Society Transactions | Oct 1983 | 6,782 |
| 12 | Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal Antonio Ayala, Mario Muñoz, Sandro Argüelles · Oxidative Medicine and Cellular Longevity | 2014 | 6,379 |
| 13 | Spectrophotometric Quantitation of Antioxidant Capacity through the Formation of a Phosphomolybdenum Complex: Specific Application to the Determination of Vitamin E Pilar Prieto, Manuel Pineda, Miguel R. Aguilar · Analytical Biochemistry | May 1999 | 6,238 |
| 14 | The Chemistry behind Antioxidant Capacity Assays Dejian Huang, Boxin Ou, Ronald L. Prior · Journal of Agricultural and Food Chemistry | 25 Feb 2005 | 6,143 |
| 15 | Oxidants, antioxidants, and the degenerative diseases of aging. B N Ames, Mark K. Shigenaga, Tory M. Hagen · Proceedings of the National Academy of Sciences | Sep 1993 | 5,991 |
| 16 | Standardized Methods for the Determination of Antioxidant Capacity and Phenolics in Foods and Dietary Supplements Ronald L. Prior, Xianli Wu, Karen M. Schaich · Journal of Agricultural and Food Chemistry | 26 Apr 2005 | 5,638 |
| 17 | Regulation of the mevalonate pathway Joseph L. Goldstein, Michael S. Brown · Nature | Feb 1990 | 5,449 |
| 18 | Flavonoids: an overview Archana N. Panche, A D Diwan, Sheela Chandra · Journal of Nutritional Science | 2016 | 5,306 |
| 19 | A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care Paul C. Hébert, George A. Wells, Morris A. Blajchman et al. · New England Journal of Medicine | 11 Feb 1999 | 5,247 |
| 20 | Determination of malonaldehyde precursor in tissues by thiobarbituric acid test Mitsuru Uchiyama, Midori Mihara · Analytical Biochemistry | May 1978 | 5,212 |
| 21 | THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS P J Randle, P. B. Garland, Charles Nicholas Hales et al. · The Lancet | Apr 1963 | 5,198 |
| 22 | Chemistry and Biological Activities of Flavonoids: An Overview Shashank Kumar, Abhay Kumar Pandey · The Scientific World JOURNAL | 2013 | 4,993 |
| 23 | Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes Meishiang Jang, Lining Cai, George Udeani et al. · Science | 10 Jan 1997 | 4,949 |
| 24 | The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer Elliott Middleton, Chithan Kandaswami, Theoharis Constantin Theoharides · Pharmacological Reviews | Dec 2000 | 4,876 |
| 25 | Flavonoids as Antioxidants Piergiorgio Pietta · Journal of Natural Products | 27 May 2000 | 4,873 |
| 26 | Oxidative Stress: Harms and Benefits for Human Health Gabriele Pizzino, Natasha Irrera, Mariapaola Cucinotta et al. · Oxidative Medicine and Cellular Longevity | 2017 | 4,835 |
| 27 | Plant Polyphenols as Dietary Antioxidants in Human Health and Disease Kanti Bhooshan Pandey, Syed Ibrahim Rizvi · Oxidative Medicine and Cellular Longevity | 2009 | 4,626 |
| 28 | Oxidative stress: oxidants and antioxidants Helmut Sies · Experimental Physiology | Mar 1997 | 4,576 |
| 29 | Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties Jin Dai, Russell J. Mumper · Molecules | 21 Oct 2010 | 4,484 |
| 30 | Leaf Senescence: Correlated with Increased Levels of Membrane Permeability and Lipid Peroxidation, and Decreased Levels of Superoxide Dismutase and Catalase Rajinder S. Dhindsa, Pamela L. Plumb-Dhindsa, Trevor A. Thorpe · Journal of Experimental Botany | 1981 | 4,480 |
| 31 | Antimicrobial activity of flavonoids T.P. Tim Cushnie, Andrew J. Lamb · International Journal of Antimicrobial Agents | 20 Oct 2005 | 4,427 |
| 32 | Antioxidant properties of phenolic compounds Catherine A Rice-Evans, Nicholas J. Miller, George Paganga · Trends in Plant Science | Apr 1997 | 4,381 |
| 33 | Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study M.G.L Hertog, Edith J. M. Feskens, Daan Kromhout et al. · The Lancet | Oct 1993 | 4,357 |
| 34 | Improving the thiobarbituric acid-reactive-substances assay for estimating lipid peroxidation in plant tissues containing anthocyanin and other interfering compounds D. Mark Hodges, John M. DeLong, Charles F. Forney et al. · Planta | 17 Feb 1999 | 4,265 |
| 35 | Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships Kelly E Heim, Anthony R. Tagliaferro, Dennis J. Bobilya · The Journal of Nutritional Biochemistry | Oct 2002 | 4,216 |
| 36 | Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies Claudine Manach, Gary Williamson, Christine Morand et al. · American Journal of Clinical Nutrition | 2005 | 4,212 |
| 37 | Polyphenols: Chemistry, Dietary Sources, Metabolism, and Nutritional Significance Laura Bravo · Nutrition Reviews | 27 Apr 2009 | 4,020 |
| 38 | First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid Osasenaga Macdonald. Ighodaro, Oluseyi Adeboye Akinloye · Alexandria Journal of Medicine | 13 Nov 2017 | 3,970 |
| 39 | Advances in flavonoid research since 1992 Jeffrey B. Harborne, Christine A. Williams · Phytochemistry | Nov 2000 | 3,961 |
| 40 | [2] Ferric reducing/antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration Iris F. F. Benzie, JJ Strain · Methods in enzymology on CD-ROM/Methods in enzymology | 1999 | 3,940 |
| 41 | The Free Radical Theory of Aging Matures Kenneth B. Beckman, Bruce N. Ames · Physiological Reviews | Apr 1998 | 3,892 |
| 42 | Antioxidant Activity of Plant Extracts Containing Phenolic Compounds Marja P. Kähkönen, Anu Hopia, Heikki J. Vuorela et al. · Journal of Agricultural and Food Chemistry | 24 Sep 1999 | 3,862 |
| 43 | Antioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products Y. Sedat Velioğlu, Giuseppe Antonio Mazza, Ling Gao et al. · Journal of Agricultural and Food Chemistry | 29 Aug 1998 | 3,861 |
| 44 | Flavonoid Biosynthesis. A Colorful Model for Genetics, Biochemistry, Cell Biology, and Biotechnology A. Winkel · PLANT PHYSIOLOGY | Jun 2001 | 3,789 |
| 45 | A new automated colorimetric method for measuring total oxidant status Özcan Erel · Clinical Biochemistry | 7 Nov 2005 | 3,756 |
| 46 | Role of Oxidative Stress in Development of Complications in Diabetes John Baynes · Diabetes | Apr 1991 | 3,719 |
| 47 | The phenolic constituents of Prunus domestica . I.—The quantitative analysis of phenolic constituents Trupti Rekha Swain, W. E. Hillis · Journal of the Science of Food and Agriculture | 1959 | 3,700 |
| 48 | Dietary Intake and Bioavailability of Polyphenols Augustin Scalbert, Gary Williamson · Journal of Nutrition | Aug 2000 | 3,674 |
| 49 | Effects of a Combination of Beta Carotene and Vitamin A on Lung Cancer and Cardiovascular Disease Gilbert S. Omenn, Gary E. Goodman, Mark D. Thornquist et al. · New England Journal of Medicine | 2 May 1996 | 3,667 |
| 50 | Comparison of ABTS, DPPH, FRAP, and ORAC assays for estimating antioxidant activity from guava fruit extracts Kriengsak Thaipong, Unaroj Boonprakob, Kevin M. Crosby et al. · Journal of Food Composition and Analysis | 3 Jun 2006 | 3,649 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.