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Most cited papers in Drug Discovery

What are the most cited papers in Drug Discovery?

The most cited paper in Drug Discovery is "HPV Screening for Cervical Cancer in Rural India" (Rengaswamy Sankaranarayanan, Bhagwan M. Nene, Surendra Srinivas Shastri et al., 2009), with 1,300 citations. Next come "Worldwide burden of cervical cancer in 2008" (1,150) and "Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L" (1,117).

Showing 50 of 100 papers. Every paper with more than 174 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 HPV Screening for Cervical Cancer in Rural India Rengaswamy Sankaranarayanan, Bhagwan M. Nene, Surendra Srinivas Shastri et al. · New England Journal of Medicine Apr 2009 1,300
2 Worldwide burden of cervical cancer in 2008 Marc Arbyn, Xavier Castellsagué, Silvia de Sanjosé et al. · Annals of Oncology Open access 7 Apr 2011 1,150
3 Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L Naima Saeed, Muhammad Rashid Khan, Maria Shabbir · BMC Complementary and Alternative Medicine Open access 15 Nov 2012 1,117
4 A cross-cultural analysis of Jammu, Kashmir and Ladakh (India) medicinal plant use Sumeet Gairola, Jyotsana Sharma, Yashbir Singh Bedi · Journal of Ethnopharmacology 18 Jun 2014 1,001
5 Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Lakshmi-Chandra Mishra, Betsy B Singh, Simon Dagenais · PubMed Aug 2000 779
6 Flavonoids as natural phenolic compounds and their role in therapeutics: an overview Rakesh Eshwarlal Mutha, Anilkumar Uttamchand Tatiya, Sanjay Javerilal Surana · Future Journal of Pharmaceutical Sciences Open access 20 Jan 2021 628
7 Review article: yeast as probiotics – Saccharomyces boulardii Dorota Czerucka, Thierry Piche, Patrick Rampal · Alimentary Pharmacology & Therapeutics 19 Jul 2007 588
8 Preliminary phytochemical screening and In vitro antioxidant activities of the aqueous extract of Helichrysum longifolium DC Olayinka Ayobami Aiyegoro, Anthony Ifeanyi Okoh · BMC Complementary and Alternative Medicine Open access 14 May 2010 535
9 Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats Akram Eidi, Maryam Eidi, Elham Davtalab Esmaeili · Phytomedicine 3 Nov 2005 517
10 Honey and Health: A Review of Recent Clinical Research. Saeed Samarghandian, Tahereh Farkhondeh, Fariborz Samini · PubMed Open access 26 May 2017 501
11 Ethnobotanical survey of medicinal plants used by people in Oriental Morocco to manage various ailments Jamila Fakchich, Mostafa Elachouri · Journal of Ethnopharmacology 28 Mar 2014 488
12 Synthesis of silver nanoparticles using leaves of Catharanthus roseus Linn. G. Don and their antiplasmodial activities S Ponarulselvam, Chellasamy Panneerselvam, Kadarkarai Murugan et al. · Asian Pacific Journal of Tropical Biomedicine Open access 30 Apr 2012 478
13 Epidemiology of knee osteoarthritis in India and related factors Chandra Prakash Pal, Pulkesh Singh, Sanjay Chaturvedi et al. · Indian Journal of Orthopaedics Open access 15 Sep 2016 465
14 An Ethnobotanical study of Medicinal Plants in high mountainous region of Chail valley (District Swat- Pakistan) Mushtaq Ahmad, Shazia Sultana, Syed Fazl-i-Hadi et al. · Journal of Ethnobiology and Ethnomedicine Open access 16 Apr 2014 428
15 Rutin: therapeutic potential and recent advances in drug delivery Shrestha Sharma, Asgar Ali, Javed Ali et al. · Expert Opinion on Investigational Drugs 25 Jun 2013 420
16 Ethnobotany of medicinal plants among the communities of Alpine and Sub-alpine regions of Pakistan Sadaf Ilyas Kayani, Mushtaq Ahmad, Shazia Sultana et al. · Journal of Ethnopharmacology 10 Feb 2015 397
17 Study of total phenol, flavonoids contents and phytochemical screening of various leaves crude extracts of locally grown Thymus vulgaris Mohammad Amzad Hossain, Khulood Ahmed Salim AL-Raqmi, Zawan Hamood AL-Mijizy et al. · Asian Pacific Journal of Tropical Biomedicine Open access 31 Aug 2013 390
18 Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature Andrea Köhrmann, Ulrike Kämmerer, Michaela Kapp et al. · BMC Cancer Open access 16 Jun 2009 390
19 Medicinal plants mediated the green synthesis of silver nanoparticles and their biomedical applications Haajira Beevi Habeeb Rahuman, Ranjithkumar Dhandapani, Santhoshini Narayanan et al. · IET Nanobiotechnology Open access 15 Apr 2022 378
20 Plants used as remedies antirheumatic and antineuralgic in the traditional medicine of Lebanon El Beyrouthy Marc, Nelly Arnold, Delelis-Dusollier Annick et al. · Journal of Ethnopharmacology 31 Aug 2008 369
21 Phyllanthus amarus: Ethnomedicinal uses, phytochemistry and pharmacology: A review Jay Patel, Priyanka Tripathi, Vikas Kumar Sharma et al. · Journal of Ethnopharmacology Oct 2011 368
22 Phytochemical analysis and evaluation of leaf and root parts of the medicinal herb, Hypochaeris radicata L. for in vitro antioxidant activities Senguttuvan Jamuna, Subramaniam Paulsamy, Krishnamoorthy Karthika · Asian Pacific Journal of Tropical Biomedicine Open access May 2014 342
23 Emergence of vancomycin resistant Staphylococcus aureus(VRSA) from a tertiary care hospital from northern part of India Hare Krishna Tiwari, Malay Ranjan Sen · BMC Infectious Diseases Open access 26 Oct 2006 338
24 Quantitative ethnomedicinal study of plants used in the skardu valley at high altitude of Karakoram-Himalayan range, Pakistan Abida Bano, Mushtaq Ahmad, Taïbi Ben Hadda et al. · Journal of Ethnobiology and Ethnomedicine Open access 9 May 2014 332
25 Biogenesis of antibacterial silver nanoparticles using the endophytic bacterium Bacillus cereus isolated from Garcinia xanthochymus Swetha Sunkar, C. Valli Nachiyar · Asian Pacific Journal of Tropical Biomedicine Open access Dec 2012 324
26 Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India Muniappan Ayyanar, S. Ignacimuthu · Journal of Ethnopharmacology 2 Feb 2011 322
27 Frequency and Factors Associated With Adverse Events Among Multi-Drug Resistant Tuberculosis Patients in Pakistan: A Retrospective Study Muhammad Atif, Waqar Habib Ahmed, Muhammad Nouman Iqbal et al. · Frontiers in Medicine Open access Mar 2022 321
28 Immunomodulatory active compounds from Tinospora cordifolia Upendra K. Sharma, Manju Bala, Neeraj Kumar et al. · Journal of Ethnopharmacology 26 Mar 2012 306
29 Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan Arshad Mehmood Abbasi, Mubarak Ali Khan, Mushtaq Ahmad et al. · Journal of Ethnopharmacology 5 Feb 2010 297
30 Ethnomedicinal plants used by local inhabitants of Jakholi block, Rudraprayag district, western Himalaya, India Ankit Singh, Mohan Chandra Nautiyal, Ripu M. Kunwar et al. · Journal of Ethnobiology and Ethnomedicine Open access 24 Aug 2017 294
31 Role of Platelet rich fibrin in wound healing: A critical review M Jayadev, VRahul Marshal, Balaram Naik et al. · Journal of Conservative Dentistry Open access 2013 287
32 Traditional medicinal plants of cold desert Ladakh—Used against kidney and urinary disorders Basant Ballabh, O. P. Chaurasia, Zakwan Ahmed et al. · Journal of Ethnopharmacology 4 May 2008 286
33 Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model Nongnut Uabundit, Jintanaporn Wattanathorn, Supaporn Mucimapura et al. · Journal of Ethnopharmacology 5 Oct 2009 281
34 The Antibiotic Principle of Seeds of Moringa oleifera and Moringa stenopetala Udo Eilert, B. Wolters, Adolf Nahrstedt · Planta Medica May 1981 279
35 Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis Yuan Wang, Shujing Chen, Kunze Du et al. · Journal of Ethnopharmacology 29 Jun 2021 270
36 The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal And Antiviral Drugs Alvis Kucers 13 Aug 1997 269
37 Parsley: a review of ethnopharmacology, phytochemistry and biological activities Mohammad Hosein Farzaei, Zahra Abbasabadi, Mohammad Reza Shams Ardekani et al. · 中医杂志:英文版 Open access Dec 2013 257
38 Resveratrol: review on therapeutic potential and recent advances in drug delivery Rudra Pangeni, Jasjeet Kaur Sahni, Javed Ali et al. · Expert Opinion on Drug Delivery 15 May 2014 256
39 Antibiotic susceptibility patterns of urinary pathogens in female outpatients Syed Esam Mahmood, Iram Shaifali, Jawed Ahmed et al. · North American Journal of Medical Sciences Open access 2012 252
40 Burden of cervical cancer and role of screening in India Saurabh Bobdey, Jignasa Sathwara, Aanchal Jain et al. · Indian Journal of Medical and Paediatric Oncology Open access Oct 2016 251
41 Development of Ayurveda – Tradition to trend Pulok Kumar Mukherjee, Ranjit Kumar Harwansh, Shiv Bahadur et al. · Journal of Ethnopharmacology 13 Sep 2016 251
42 Ethnopharmacological survey of medicinal herbs in Jordan, the Northern Badia region Muhammed H. Alzweiri, Ali Al Sarhan, Kamal Mansi et al. · Journal of Ethnopharmacology 17 Feb 2011 249
43 Nitrogen-Containing Heterocycles as Anticancer Agents: An Overview Damanpreet Kaur Lang, Rajwinder Kaur, Rashmi Arora et al. · Anti-Cancer Agents in Medicinal Chemistry 6 Jul 2020 246
44 Antimicrobial Capacity of Plant Polyphenols against Gram-positive Bacteria: A Comprehensive Review Francisco Javier Álvarez‐Martínez, Enrique Barrajón‐Catalán, José Antonio Encinar et al. · Current Medicinal Chemistry 8 Oct 2018 246
45 The Genus Rumex: Review of traditional uses, phytochemistry and pharmacology Andrea Vasas, Orsolya Orbán-Gyapai, Judit Hohmann · Journal of Ethnopharmacology 14 Sep 2015 246
46 Methotrexate: a detailed review on drug delivery and clinical aspects Zulfequar Ahamad Khan, Rahul Tripathi, Brahmeshwar Mishra · Expert Opinion on Drug Delivery 18 Jan 2012 245
47 Anti-Inflammatory Drugs and Herbs with Special Emphasis on Herbal Medicines for Countering Inflammatory Diseases and Disorders - A Review Mohd. Iqbal Yatoo, Arumugam Gopalakrishnan, Archana Saxena et al. · Recent Patents on Inflammation & Allergy Drug Discovery 16 Jan 2018 244
48 Prevalence of hyperuricemia and the relationship between serum uric acid and obesity: A study on Bangladeshi adults Nurshad Ali, Rasheda Perveen, Shahnaz Rahman et al. · PLoS ONE Open access Nov 2018 243
49 Antioxidant activity of methanol extracts of different parts of Lantana camara Badakhshan Mahdi-Pour, Subramanion Lachumy Jothy, Lachimanan Yoga Latha et al. · Asian Pacific Journal of Tropical Biomedicine Open access Dec 2012 243
50 Antibiotic additive and synergistic action of rutin, morin and quercetin against methicillin resistant Staphylococcus aureus Muhammad Usman Amin, Muhammad Khurram, Baharullah Khattak et al. · BMC Complementary and Alternative Medicine Open access 10 Mar 2015 237

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.