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Subfield · Emergency Medicine

Most cited papers in Emergency Medicine

What are the most cited papers in Emergency Medicine?

The most cited paper in Emergency Medicine is "A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation" (Mary E. Charlson, Peter Pompei, Kathy L. Aleš et al., 1987), with 50,676 citations. Next come "APACHE II" (13,863) and "Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline" (10,622).

Showing 50 of 100 papers. Every paper with more than 1,912 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation Mary E. Charlson, Peter Pompei, Kathy L. Aleš et al. · Journal of Chronic Diseases 1987 50,676
2 APACHE II William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine Oct 1985 13,863
3 Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline Michael F. Holick, Neil Binkley, Heike Annette Bischoff-Ferrari et al. · The Journal of Clinical Endocrinology & Metabolism Open access 7 Jun 2011 10,622
4 The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia Daniel A. Arber, Attilio Orazi, Robert Paul Hasserjian et al. · Blood Open access 12 Apr 2016 10,371
5 The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. Susan P. Baker, Brian O’Neill, William F. Haddon et al. · PubMed Mar 1974 8,021
6 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Edward C. Jauch, Jeffrey L. Saver, Harold P. Adams et al. · Stroke Open access Feb 2013 7,675
7 Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults Lionel A. Mandell, Richard G. Wunderink, Antonio Anzueto et al. · Clinical Infectious Diseases Open access 3 Feb 2007 6,286
8 Updating and Validating the Charlson Comorbidity Index and Score for Risk Adjustment in Hospital Discharge Abstracts Using Data From 6 Countries Hude Quan, Bing Li, Chantal Marie Couris et al. · American Journal of Epidemiology 17 Feb 2011 6,044
9 A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase Phyllis Frosst, Henk J. Blom, Renate Milos et al. · Nature Genetics Open access May 1995 5,732
10 Proposals for the Classification of the Acute Leukaemias F rench ‐A merican ‐B ritish (FAB) C o‐operative G roup John M. Bennett, Daniel Catovsky, Marie‐Theregse Daniel et al. · British Journal of Haematology Aug 1976 5,633
11 Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced Hypothermia Stephen A. Bernard, Timothy W. Gray, Michael Buist et al. · New England Journal of Medicine Open access 21 Feb 2002 5,437
12 Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 Laura Evans et al. · Intensive Care Medicine Open access 2 Oct 2021 5,314
13 Mild Therapeutic Hypothermia to Improve the Neurologic Outcome after Cardiac Arrest The Hypothermia after Cardiac Arrest Study Group · New England Journal of Medicine 21 Feb 2002 5,244
14 Rehospitalizations among Patients in the Medicare Fee-for-Service Program Stephen F. Jencks, Mark V. Williams, Eric A. Coleman · New England Journal of Medicine Apr 2009 5,226
15 Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men Robert M. Grant et al. · New England Journal of Medicine Open access 23 Nov 2010 5,186
16 The Acute Respiratory Distress Syndrome Michael A. Matthay · New England Journal of Medicine 30 May 1996 4,944
17 The Danish National Patient Registry: a review of content, data quality, and research potential Morten Schmidt, Sigrún Alba Jóhannesdóttir Schmidt, Jakob Lynge Sandegaard et al. · Clinical Epidemiology Open access Nov 2015 4,900
18 The Acute Respiratory Distress Syndrome Lorraine B. Ware, Michael A. Matthay · New England Journal of Medicine 4 May 2000 4,708
19 The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes James W. Vardiman, Jüergen Thiele, Daniel A. Arber et al. · Blood Open access 9 Apr 2009 4,457
20 Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition Nancy Carney, Annette M Totten, Cindy O’Reilly et al. · Neurosurgery 20 Sep 2016 4,421
21 Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection David D. Ho, Avidan Uriel Neumann, Alan S. Perelson et al. · Nature 1995 4,310
22 Myocardial Reperfusion Injury Derek M. Yellon, Derek John Hausenloy · New England Journal of Medicine 12 Sep 2007 3,755
23 The Epidemiology and Impact of Traumatic Brain Injury Jean Ann Langlois, Wesley Rutland-Brown, Marlena M. Wald · Journal of Head Trauma Rehabilitation Sep 2006 3,667
24 The Danish Civil Registration System as a tool in epidemiology Morten Schmidt, Lars Pedersen, Henrik Toft Sørensen · European Journal of Epidemiology 25 Jun 2014 3,514
25 Mesenchymal and haematopoietic stem cells form a unique bone marrow niche Simón Méndez‐Ferrer, Tatyana V. Michurina, Francesca Ferraro et al. · Nature Open access Aug 2010 3,419
26 A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES Morris J. Karnovsky, LOGAN ROOTS · Journal of Histochemistry & Cytochemistry Open access Mar 1964 3,395
27 Estimating the global incidence of traumatic brain injury Michael Christopher Dewan, Abbas Rattani, Saksham Gupta et al. · Journal of neurosurgery 27 Apr 2018 3,356
28 Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection David L. Paterson, Susan Swindells, Jeffrey A. Mohr et al. · Annals of Internal Medicine 4 Jul 2000 3,332
29 Revised International Prognostic Scoring System for Myelodysplastic Syndromes Peter L. Greenberg et al. · Blood Open access 28 Jun 2012 3,195
30 Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction Maria Teresa La Rovere, J. Thomas Bigger, Gregory M. Marcus et al. · The Lancet Open access Feb 1998 3,124
31 Viral Load and Heterosexual Transmission of Human Immunodeficiency Virus Type 1 Thomas C. Quinn, Maria Joan Wawer, Nelson Kaulukusi Sewankambo et al. · New England Journal of Medicine Open access 30 Mar 2000 3,081
32 The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994 Miriam J. Alter, Deanna Kruszon-Moran, Omana V. Nainan et al. · New England Journal of Medicine Open access 19 Aug 1999 3,028
33 Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1) John A. Kellum, Norbert Hendrik Lameire, for the KDIGO AKI Guideline Work Group · Critical Care Open access 2013 2,924
34 The APACHE III Prognostic System Daniel Teres, Stanley A. Lemeshow · CHEST Journal Open access Dec 1992 2,897
35 Kaposi's Sarcoma–Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity–Based Lymphomas Ethel Cesarman, Yuan Chang, Patrick S. Moore et al. · New England Journal of Medicine Open access 4 May 1995 2,885
36 Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Marc Alan Pfeffer, Eugene Braunwald · Circulation Open access Apr 1990 2,883
37 Intraaortic Balloon Support for Myocardial Infarction with Cardiogenic Shock Hölger Thiele, Uwe Zeymer, Franz–Josef Neumann et al. · New England Journal of Medicine Open access 27 Aug 2012 2,867
38 A penetration-aspiration scale John C. Rosenbek, Jo Anne Robbins, Ellen B. Roecker et al. · Dysphagia 1996 2,805
39 Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest Niklas Nielsen et al. · New England Journal of Medicine Open access 17 Nov 2013 2,799
40 The Barthel ADL Index: A reliability study Christine Collin, Derick T Wade, S Davies et al. · International Disability Studies 1988 2,788
41 Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease Daniel H. Present, Paul Rutgeerts, Stephan Targan et al. · New England Journal of Medicine Open access 6 May 1999 2,765
42 Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study Daniel D. Murray, Kazuo Suzuki, Matthew G. Law et al. · PLoS ONE Open access 14 Oct 2015 2,742
43 Bone Marrow Transplant Rosemary C. Ford, Seth H. Eisenberg · Nursing Clinics of North America Jun 1990 2,735
44 European Resuscitation Council Guidelines for Resuscitation 2010 Section 4. Adult advanced life support Charles D. Deakin, Jerry P. Nolan, Jasmeet Soar et al. · Resuscitation Oct 2010 2,717
45 Prognosis in HIV-1 Infection Predicted by the Quantity of Virus in Plasma John W. Mellors, Charles R. Rinaldo, Phalguni Gupta et al. · Science 24 May 1996 2,716
46 Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 Christina Fitzmaurice et al. · JAMA Oncology Open access628 authors 27 Sep 2019 2,699
47 A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less Scott M. Hammer, Kathleen Squires, Michael D. Hughes et al. · New England Journal of Medicine Open access 11 Sep 1997 2,687
48 Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research Andrew I.R. Maas et al. · The Lancet Neurology Open access335 authors 6 Nov 2017 2,659
49 A National Evaluation of the Effect of Trauma-Center Care on Mortality Ellen J. MacKenzie, Frederick P. Rivara, Gregory Jerome Jurkovich et al. · New England Journal of Medicine Open access 25 Jan 2006 2,600
50 Consensus statement on concussion in sport: the 4th International Conference on Concussion in Sport held in Zurich, November 2012 Paul Robert McCrory et al. · British Journal of Sports Medicine Open access 11 Mar 2013 2,596

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.