Subfield · Gastroenterology
Most cited papers in Gastroenterology
What are the most cited papers in Gastroenterology?
The most cited paper in Gastroenterology is "Comprehensive molecular characterization of gastric adenocarcinoma" (Adam Joel Bass et al., 2014), with 6,680 citations. Next come "Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer" (6,432) and "Diversity, stability and resilience of the human gut microbiota" (5,727).
Showing 50 of 99 papers. Every paper with more than 1,710 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Comprehensive molecular characterization of gastric adenocarcinoma Adam Joel Bass et al. · Nature | 23 Jul 2014 | 6,680 |
| 2 | Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer David Cunningham, William Allum, Sally Patricia Stenning et al. · New England Journal of Medicine | 6 Jul 2006 | 6,432 |
| 3 | Diversity, stability and resilience of the human gut microbiota Catherine Lozupone, Jesse Stombaugh, Jeffrey I. Gordon et al. · Nature | Sep 2012 | 5,727 |
| 4 | The Microbiota-Gut-Brain Axis John F. Cryan et al. · Physiological Reviews | 28 Aug 2019 | 5,217 |
| 5 | The gut microbiota shapes intestinal immune responses during health and disease June L. Round, Sarkis K. Mazmanian · Nature reviews. Immunology | 3 Apr 2009 | 5,124 |
| 6 | Gastric cancer Elizabeth Catherine Smyth, Magnus Nilsson, Heike Irmgard Grabsch et al. · The Lancet | Aug 2020 | 5,024 |
| 7 | Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease Luke Jostins et al. · Nature | 31 Oct 2012 | 4,928 |
| 8 | Host-Gut Microbiota Metabolic Interactions Jeremy Kirk Nicholson, Elaine C. Holmes, James K. Kinross et al. · Science | 6 Jun 2012 | 4,834 |
| 9 | Functional Bowel Disorders George F. Longstreth, Wade Thompson, William D. Chey et al. · Gastroenterology | Apr 2006 | 4,801 |
| 10 | Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour John F. Cryan, Timothy G. Dinan · Nature reviews. Neuroscience | 12 Sep 2012 | 4,624 |
| 11 | Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors Seiichi Hirota, Koji Isozaki, Yasuhiro Moriyama et al. · Science | 23 Jan 1998 | 4,517 |
| 12 | Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors George D. Demetri et al. · New England Journal of Medicine | 15 Aug 2002 | 4,425 |
| 13 | Gut Microbiota in Health and Disease Inna Sekirov, Shannon Russell, L. Caetano M. Antunes et al. · Physiological Reviews | Jul 2010 | 4,212 |
| 14 | The Montreal Definition and Classification of Gastroesophageal Reflux Disease: A Global Evidence-Based Consensus Nimish B. Vakil, Sander Veldhuyzen van Zanten, Peter J. Kahrilas et al. · The American Journal of Gastroenterology | Aug 2006 | 3,941 |
| 15 | The Human Intestinal Microbiome in Health and Disease Susan V. Lynch, Oluf Borbye Pedersen · New England Journal of Medicine | 14 Dec 2016 | 3,726 |
| 16 | Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species Koji Atarashi, Takeshi Tanoue, Tatsuichiro Shima et al. · Science | 23 Dec 2010 | 3,724 |
| 17 | Introduction to the human gut microbiota Elizabeth Thursby, Nathalie Juge · Biochemical Journal | 16 May 2017 | 3,635 |
| 18 | Chemoradiotherapy after Surgery Compared with Surgery Alone for Adenocarcinoma of the Stomach or Gastroesophageal Junction John Smyth Macdonald, Stephen R. Smalley, Jacqueline Benedetti et al. · New England Journal of Medicine | 6 Sep 2001 | 3,522 |
| 19 | What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases Emanuele Rinninella, Pauline Celine Raoul, Marco Cintoni et al. · Microorganisms | 10 Jan 2019 | 3,481 |
| 20 | Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis Jurenne D. Hooi, Wan Ying Lai, Wee Khoon Ng et al. · Gastroenterology | 27 Apr 2017 | 3,471 |
| 21 | Diagnosis of gastrointestinal stromal tumors: A consensus approach Christopher D.�M. Fletcher, Jules J. Berman, Christopher L. Corless et al. · Human Pathology | May 2002 | 3,469 |
| 22 | The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics | 2001 | 3,417 |
| 23 | The role of short-chain fatty acids in microbiota–gut–brain communication Boushra Dalile, Lukas Van Oudenhove, Bram Vervliet et al. · Nature Reviews Gastroenterology & Hepatology | 23 May 2019 | 3,399 |
| 24 | Stool Form Scale as a Useful Guide to Intestinal Transit Time Stephen J. Lewis, K W Heaton · Scandinavian Journal of Gastroenterology | 1997 | 3,301 |
| 25 | The Triad of Sleep Apnea, Hypertension, and Chronic Kidney Disease: A Spectrum of Common Pathology Fahad Aziz, Kunal R. Chaudhary · Cardiorenal Medicine | 4 Nov 2016 | 3,278 |
| 26 | Wireless capsule endoscopy Gavriel J. Iddan, Gavriel Meron, Arkady Glukhovsky et al. · Nature | 25 May 2000 | 3,074 |
| 27 | Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma Jesper Lagergren, Reinhold Bergström, Anders Lindgren et al. · New England Journal of Medicine | 18 Mar 1999 | 3,048 |
| 28 | The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication Ygor Parladore Silva, Andressa Bernardi, Rudimar Luiz Frozza · Frontiers in Endocrinology | 31 Jan 2020 | 3,047 |
| 29 | A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility Mahesh S. Desai, Anna Maria Seekatz, Nicole M. Koropatkin et al. · Cell | Nov 2016 | 2,927 |
| 30 | Bowel Disorders Brian E. Lacy, Fermín Mearin, Lin Chang et al. · Gastroenterology | May 2016 | 2,879 |
| 31 | Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children Alexander Edward Dela Cruz Drilon et al. · New England Journal of Medicine | 21 Feb 2018 | 2,827 |
| 32 | Rome III functional constipation and irritable bowel syndrome with constipation are similar disorders within a spectrum of sensitization, regulated by serotonin. Chander Shekhar, Monaghan Pj, Jane Morris et al. · IRIS Research product catalog (Sapienza University of Rome) | 2013 | 2,766 |
| 33 | European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease Steffen Husby, Sibylle Koletzko, Ilma Rita Korponay-Szabo et al. · Journal of Pediatric Gastroenterology and Nutrition | 4 Oct 2011 | 2,706 |
| 34 | Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial Salah‐Eddin Al‐Batran et al. · The Lancet | 11 Apr 2019 | 2,700 |
| 35 | Gut biogeography of the bacterial microbiota Gregory P. Donaldson, S. Melanie Lee, Sarkis K. Mazmanian · Nature Reviews Microbiology | 26 Oct 2015 | 2,669 |
| 36 | Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial George D. Demetri, Allan T. van Oosterom, Christopher R. Garrett et al. · The Lancet | Oct 2006 | 2,626 |
| 37 | The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Marilia Carabotti, Annunziata Scirocco, M.A. Maselli et al. · PubMed | 2 Apr 2015 | 2,596 |
| 38 | Two Hundred Gastrointestinal Stromal Tumors Ronald P. DeMatteo, Jonathan J. Lewis, Denis H. Y. Leung et al. · Annals of Surgery | 2000 | 2,559 |
| 39 | Population-level analysis of gut microbiome variation Gwen Falony et al. · Science | 28 Apr 2016 | 2,527 |
| 40 | Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability Patrice D. Cani, Sam Possemiers, Tom Van de Wiele et al. · Gut | 24 Feb 2009 | 2,525 |
| 41 | Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV Douglas A. Drossman · Gastroenterology | May 2016 | 2,463 |
| 42 | The Functional Gastrointestinal Disorders and the Rome III Process Douglas A. Drossman · Gastroenterology | Apr 2006 | 2,436 |
| 43 | Functional Gastroduodenal Disorders Jan F. Tack, Nicholas J. Talley, Michael Camilleri et al. · Gastroenterology | Apr 2006 | 2,419 |
| 44 | Functional bowel disorders and functional abdominal pain Wade Thompson, George F. Longstreth, Douglas A. Drossman et al. · Gut | Sep 1999 | 2,395 |
| 45 | The gut microbiota and host health: a new clinical frontier Julian Roberto Marchesi, David Adams, Francesca Fava et al. · Gut | 2 Sep 2015 | 2,357 |
| 46 | Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification Lars R. Lundell, John Dent, J R Bennett et al. · Gut | Aug 1999 | 2,323 |
| 47 | Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor Michael Charles Heinrich, Christopher L. Corless, George D. Demetri et al. · Journal of Clinical Oncology | 25 Nov 2003 | 2,319 |
| 48 | PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors Michael Charles Heinrich, Christopher L. Corless, Anette U. Duensing et al. · Science | 30 Jan 2003 | 2,311 |
| 49 | Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study Ami D. Sperber et al. · Gastroenterology | 12 Apr 2020 | 2,280 |
| 50 | U. S. Householder survey of functional gastrointestinal disorders Douglas A. Drossman, Zhiming Li, Eileen Andruzzi et al. · Digestive Diseases and Sciences | Sep 1993 | 2,215 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.