Most cited papers in Neurology (Neuroscience)
What are the most cited papers in Neurology?
The most cited paper in Neurology is "[Japanese version of the Neuropsychiatric Inventory--a scoring system for neuropsychiatric disturbance in dementia patients]." (Nobutsugu Hirono, Etsuro Mori, Yoshitaka Ikejiri et al., 1997), with 20,864 citations. Next come "Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment." (12,468) and "A synaptic model of memory: long-term potentiation in the hippocampus" (11,655).
Showing 50 of 100 papers. Every paper with more than 3,081 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | [Japanese version of the Neuropsychiatric Inventory--a scoring system for neuropsychiatric disturbance in dementia patients]. Nobutsugu Hirono, Etsuro Mori, Yoshitaka Ikejiri et al. · PubMed | Mar 1997 | 20,864 |
| 2 | Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Harold P. Adams, Birgitte H. Bendixen, L. Jaap Kappelle et al. · Stroke | 1993 | 12,468 |
| 3 | A synaptic model of memory: long-term potentiation in the hippocampus T.V.P. Bliss, Graham L. Collingridge · Nature | 1993 | 11,655 |
| 4 | Staging of brain pathology related to sporadic Parkinson’s disease Heiko Braak, Kelly Del Tredici, Udo Rüb et al. · Neurobiology of Aging | 28 Dec 2002 | 10,980 |
| 5 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Marilyn S. Albert, Steven T. DeKosky, Dennis W. Dickson et al. · Alzheimer s & Dementia | 22 Apr 2011 | 10,419 |
| 6 | Exploring the full spectrum of macrophage activation David M. Mosser, Justin P. Edwards · Nature reviews. Immunology | 25 Nov 2008 | 9,246 |
| 7 | Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity Elisabetta Polazzi, Ilaria Mengoni, Marco Caprini et al. · Neurosignals | 9 May 2012 | 9,018 |
| 8 | α-Synuclein in Lewy bodies Maria Grazia Spillantini, Marie Luise Schmidt, Virginia M.‐Y. Lee et al. · Nature | 28 Aug 1997 | 8,529 |
| 9 | Neurotoxic reactive astrocytes are induced by activated microglia Shane A. Liddelow et al. · Nature | 2017 | 8,364 |
| 10 | Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease Mihael H. Polymeropoulos, Christian N. Lavedan, Elisabeth Leroy et al. · Science | 27 Jun 1997 | 8,336 |
| 11 | Glutamate neurotoxicity and diseases of the nervous system Dennis W. Choi · Neuron | Oct 1988 | 8,019 |
| 12 | MDS clinical diagnostic criteria for Parkinson's disease Ronald B. Postuma, Daniela Berg, Matthew Stern et al. · Movement Disorders | Oct 2015 | 7,758 |
| 13 | Reversible middle cerebral artery occlusion without craniectomy in rats. Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke | 1989 | 7,562 |
| 14 | From inflammation to sickness and depression: when the immune system subjugates the brain Robert Dantzer, Jason C. O’Connor, Gregory G. Freund et al. · Nature reviews. Neuroscience | 12 Dec 2007 | 7,434 |
| 15 | The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology Karen Bedard, Karl‐Heinz Krause · Physiological Reviews | 2007 | 7,002 |
| 16 | ShuffleNet V2: Practical Guidelines for Efficient CNN Architecture Design Ningning Ma, Xiangyu Zhang, Hai-Tao Zheng et al. · Lecture notes in computer science | 2018 | 6,903 |
| 17 | The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) Bjoern H. Menze et al. · IEEE Transactions on Medical Imaging | 4 Dec 2014 | 6,843 |
| 18 | Changes of Intestinal Functions in Liver Cirrhosis Hiroshi Fukui, Reiner Wiest · Inflammatory Intestinal Diseases | 2016 | 6,814 |
| 19 | Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science | 5 Oct 2006 | 6,756 |
| 20 | THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE Richard C. Graham, Morris J. Karnovsky · Journal of Histochemistry & Cytochemistry | Apr 1966 | 6,512 |
| 21 | Place navigation impaired in rats with hippocampal lesions Richard Morris, Paul Garrud, J. N. P. Rawlins et al. · Nature | Jun 1982 | 6,447 |
| 22 | Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines Peter J. Murray et al. · Immunity | Jul 2014 | 6,444 |
| 23 | Neuroinflammation in Alzheimer's disease Michael Thomas Heneka et al. · The Lancet Neurology | 16 Mar 2015 | 6,318 |
| 24 | Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen · Science | 14 Apr 2005 | 5,970 |
| 25 | A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease Hadas Keren‐Shaul, Amit Spinrad, Assaf Weiner et al. · Cell | Jun 2017 | 5,874 |
| 26 | Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation Michael Andreas Nitsche, Walter Paulus · The Journal of Physiology | Sep 2000 | 5,776 |
| 27 | Astrocyte–endothelial interactions at the blood–brain barrier N. Joan Abbott, Lars Rönnbäck, Elisabeth Hansson · Nature reviews. Neuroscience | 21 Dec 2005 | 5,649 |
| 28 | Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research Símone Rossi, Mark Hallett, Paolo Maria Rossini et al. · Clinical Neurophysiology | 15 Oct 2009 | 5,541 |
| 29 | El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis Benjamin Rix Brooks, Robert G. Miller, Michael Swash et al. · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders | 2000 | 5,487 |
| 30 | Prions Stanley Ben Prusiner · Proceedings of the National Academy of Sciences | 10 Nov 1998 | 5,428 |
| 31 | Astrocytes: biology and pathology Michael V. Sofroniew, Harry V. Vinters · Acta Neuropathologica | 9 Dec 2009 | 5,277 |
| 32 | Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages Florent Ginhoux, Melanie Greter, Marylène Leboeuf et al. · Science | 21 Oct 2010 | 5,266 |
| 33 | Alzheimer's disease Philip Scheltens, Bart De Strooper, Miia Kivipelto et al. · The Lancet | 2 Mar 2021 | 5,240 |
| 34 | Monocyte and macrophage heterogeneity Siamon Gordon, Philip R. Taylor · Nature reviews. Immunology | Dec 2005 | 5,210 |
| 35 | Structure and function of the blood–brain barrier N. Joan Abbott, Adjanie Patabendige, Diana E. M. Dolman et al. · Neurobiology of Disease | 6 Aug 2009 | 5,185 |
| 36 | Vascular dementia Gustavo C. Román et al. · Neurology | Feb 1993 | 4,937 |
| 37 | Exercise training increases size of hippocampus and improves memory Kirk I. Erickson, Michelle W. Voss, Ruchika Shaurya Prakash et al. · Proceedings of the National Academy of Sciences | 31 Jan 2011 | 4,886 |
| 38 | Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice Patrice D. Cani, Rodrigo Bibiloni, Claude Knauf et al. · Diabetes | 27 Feb 2008 | 4,821 |
| 39 | Current Concepts in Mild Cognitive Impairment Ronald C. Petersen, Rachelle Smith Doody, Alexander Kurz et al. · Archives of Neurology | Dec 2001 | 4,821 |
| 40 | Inflammation and Alzheimer's disease Haruhiko Akiyama · Neurobiology of Aging | Jun 2000 | 4,553 |
| 41 | A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD Alan Edward Renton et al. · Neuron | 22 Sep 2011 | 4,545 |
| 42 | Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B William E. Klunk et al. · Annals of Neurology | 21 Jan 2004 | 4,528 |
| 43 | Microglia: a sensor for pathological events in the CNS Georg W. Kreutzberg · Trends in Neurosciences | Aug 1996 | 4,410 |
| 44 | Multiple sclerosis Alastair Compston, Alasdair J. Coles · The Lancet | Oct 2008 | 4,397 |
| 45 | Synaptic Pruning by Microglia Is Necessary for Normal Brain Development Rosa Chiara Paolicelli, Giulia Bolasco, Francesca Pagani et al. · Science | 21 Jul 2011 | 4,383 |
| 46 | Theta Burst Stimulation of the Human Motor Cortex Ying‐Zu Huang, Mark John Edwards, Elisabeth Rounis et al. · Neuron | 2005 | 4,260 |
| 47 | Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin Lyudmila V. Borovikova, Svetlana Ivanova, Minghuang Zhang et al. · Nature | May 2000 | 4,235 |
| 48 | Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner Dorothy P. Schafer, Emily K. Lehrman, Amanda G. Kautzman et al. · Neuron | May 2012 | 4,228 |
| 49 | Succinate is an inflammatory signal that induces IL-1β through HIF-1α Gillian M. Tannahill et al. · Nature | 22 Mar 2013 | 4,197 |
| 50 | Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al. · Science | 17 Jun 1994 | 4,179 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.