Subfield · Ophthalmology
Most cited papers in Ophthalmology
What are the most cited papers in Ophthalmology?
The most cited paper in Ophthalmology is "Repertoires of Autophagy in the Pathogenesis of Ocular Diseases" (Yujie Li, Qin Li Jiang, Guo-Fan Cao et al., 2015), with 16,339 citations. Next come "Optical Coherence Tomography" (13,894) and "The biology of VEGF and its receptors" (9,633).
Showing 50 of 100 papers. Every paper with more than 1,612 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Repertoires of Autophagy in the Pathogenesis of Ocular Diseases Yujie Li, Qin Li Jiang, Guo-Fan Cao et al. · Cellular Physiology and Biochemistry | 2015 | 16,339 |
| 2 | Optical Coherence Tomography David T. Huang, Eric A. Swanson, Charles P. Lin et al. · Science | 22 Nov 1991 | 13,894 |
| 3 | The biology of VEGF and its receptors Napoleone Ferrara, Hans‐Peter Gerber, Jennifer E. LeCouter · Nature Medicine | 30 May 2003 | 9,633 |
| 4 | Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs Varun Gulshan, Lily Peng, Marc Coram et al. · JAMA | 29 Nov 2016 | 7,873 |
| 5 | Mutation and Cancer: Statistical Study of Retinoblastoma Alfred G. Knudson · Proceedings of the National Academy of Sciences | Apr 1971 | 7,700 |
| 6 | The number of people with glaucoma worldwide in 2010 and 2020 Harry A. Quigley · British Journal of Ophthalmology | 17 Feb 2006 | 7,489 |
| 7 | Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040 Yih Chung Tham, Li Xiang, Tien Yin Wong et al. · Ophthalmology | 26 Jun 2014 | 7,211 |
| 8 | Ranibizumab for Neovascular Age-Related Macular Degeneration Philip J. Rosenfeld, David M. Brown, Jeffrey S. Heier et al. · New England Journal of Medicine | 4 Oct 2006 | 5,931 |
| 9 | Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis Wan Ling Wong, Xinyi Su, Xiang Li et al. · The Lancet Global Health | 3 Jan 2014 | 5,452 |
| 10 | Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy Stefano De Cillà, Serena Farruggio, Stela Vujosevic et al. · Cellular Physiology and Biochemistry | 2017 | 5,140 |
| 11 | Global Prevalence and Major Risk Factors of Diabetic Retinopathy Joanne Wen Yee Yau et al. · Diabetes Care | 2 Feb 2012 | 5,033 |
| 12 | Complement Factor H Polymorphism in Age-Related Macular Degeneration Robert J. Klein, Caroline J. Zeiss, Emily Y. Chew et al. · Science | 10 Mar 2005 | 4,552 |
| 13 | Standardization of Uveitis Nomenclature for Reporting Clinical Data. Results of the First International Workshop Douglas A. Jabs, Robert Burton Nussenblatt, James Todd Rosenbaum · American Journal of Ophthalmology | 19 Jul 2005 | 4,424 |
| 14 | The Pathophysiology and Treatment of Glaucoma Robert Neal Weinreb, Tin Aung, Felipe Andrade Medeiros · JAMA | 13 May 2014 | 4,238 |
| 15 | Ridge-Based Vessel Segmentation in Color Images of the Retina Joes Staal, Michael D. Abràmoff, Meindert Niemeijer et al. · IEEE Transactions on Medical Imaging | Apr 2004 | 4,213 |
| 16 | Global data on visual impairment in the year 2002. Serge Resnikoff, Donatella Pascolini, Daniel Etya’ale et al. · PubMed | Nov 2004 | 4,206 |
| 17 | Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis Derek K. Chu et al. · The Lancet | Jun 2020 | 4,111 |
| 18 | Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales C. P. Wilkinson, Frederick L. Ferris, Ronald Klein et al. · Ophthalmology | Sep 2003 | 3,812 |
| 19 | Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders Lloyd Paul Aiello, Robert L. Avery, Paul G. Arrigg et al. · New England Journal of Medicine | Dec 1994 | 3,806 |
| 20 | Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Ning Tang, Huan Bai, Xing Chen et al. · Journal of Thrombosis and Haemostasis | 27 Mar 2020 | 3,744 |
| 21 | The Ocular Hypertension Treatment Study Michael A. Kass · Archives of Ophthalmology | Jun 2002 | 3,729 |
| 22 | Ranibizumab versus Verteporfin for Neovascular Age-Related Macular Degeneration David M. Brown, Peter K. Kaiser, Mark Michels et al. · New England Journal of Medicine | 4 Oct 2006 | 3,535 |
| 23 | Selective Photothermolysis: Precise Microsurgery by Selective Absorption of Pulsed Radiation R. Rox Anderson, John Albert Parrish · Science | 29 Apr 1983 | 3,481 |
| 24 | Reduction of Intraocular Pressure and Glaucoma Progression Anders Heijl · Archives of Ophthalmology | Oct 2002 | 3,356 |
| 25 | Voriconazole versus Amphotericin B for Primary Therapy of Invasive Aspergillosis Raoul Herbrecht et al. · New England Journal of Medicine | 8 Aug 2002 | 3,326 |
| 26 | Femtosecond laser micromachining in transparent materials Rafael R. Gattass, Eric Mazur · Nature Photonics | 31 Mar 2008 | 3,246 |
| 27 | Diabetic retinopathy Ning Cheung, Paul Mitchell, Tien Yin Wong · The Lancet | 29 Jun 2010 | 3,202 |
| 28 | Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study Yasuo Ohkubo, Hideki Kishikawa, Eiichi Araki et al. · Diabetes Research and Clinical Practice | May 1995 | 3,105 |
| 29 | When to use the B onferroni correction Richard A. Armstrong · Ophthalmic and Physiological Optics | 2 Apr 2014 | 3,088 |
| 30 | The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product Nicholas J. Dyson, Peter M. Howley, Karl Münger et al. · Science | 17 Feb 1989 | 3,072 |
| 31 | Epidemiology and Outcome of Zygomycosis: A Review of 929 Reported Cases Maureen M. Roden, Theoklis E. Zaoutis, Wendy L. Buchanan et al. · Clinical Infectious Diseases | 5 Aug 2005 | 3,065 |
| 32 | Number of people with glaucoma worldwide. H A Quigley · British Journal of Ophthalmology | May 1996 | 3,063 |
| 33 | A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma Stephen Henry Friend, René Bernards, Snezna Rogelj et al. · Nature | Oct 1986 | 2,994 |
| 34 | The Lens Opacities Classification System III L.T. Chylack · Archives of Ophthalmology | Jun 1993 | 2,929 |
| 35 | The Retinal Pigment Epithelium in Visual Function Olaf Strauß · Physiological Reviews | 29 Jun 2005 | 2,859 |
| 36 | Neuropsychological assessment, 3rd ed. Muriel D. Lezak | 1995 | 2,827 |
| 37 | Prevalence of Age-Related Macular Degeneration in the United States The Eye Diseases Prevalence Research Group* · Archives of Ophthalmology | Apr 2004 | 2,760 |
| 38 | Clinically applicable deep learning for diagnosis and referral in retinal disease Jeffrey De Fauw et al. · Nature Medicine | 6 Aug 2018 | 2,719 |
| 39 | Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib Caroline Robert et al. · New England Journal of Medicine | 16 Nov 2014 | 2,718 |
| 40 | Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration The CATT Research Group · New England Journal of Medicine | 28 Apr 2011 | 2,681 |
| 41 | The Ocular Hypertension Treatment Study Mae O. Gordon · Archives of Ophthalmology | Jun 2002 | 2,659 |
| 42 | Locating blood vessels in retinal images by piecewise threshold probing of a matched filter response A.D. Hoover, Valentina L. Kouznetsova, Michael H. Goldbaum · IEEE Transactions on Medical Imaging | Mar 2000 | 2,618 |
| 43 | Revised diagnostic criteria for neuromyelitis optica Dean M. Wingerchuk, Vanda A. Lennon, Sean Joseph Pittock et al. · Neurology | May 2006 | 2,585 |
| 44 | Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration Jeffrey S. Heier, David M. Brown, Victor N. Chong et al. · Ophthalmology | 17 Oct 2012 | 2,522 |
| 45 | Complement Factor H Polymorphism and Age-Related Macular Degeneration Albert O. Edwards, Robert Ritter, Kenneth J. Abel et al. · Science | 10 Mar 2005 | 2,467 |
| 46 | Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes Daniel Shu Wei Ting et al. · JAMA | 12 Dec 2017 | 2,445 |
| 47 | Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration Jonathan L. Haines, Michael A. Hauser, Silke Schmidt et al. · Science | 10 Mar 2005 | 2,436 |
| 48 | Global Prevalence of Diabetic Retinopathy and Projection of Burden through 2045 Zhen Ling Teo, Yih Chung Tham, Marco Yu et al. · Ophthalmology | May 2021 | 2,388 |
| 49 | The definition and classification of glaucoma in prevalence surveys Paul J. Foster · British Journal of Ophthalmology | Feb 2002 | 2,388 |
| 50 | Pegaptanib for Neovascular Age-Related Macular Degeneration Evangelos S. Gragoudas, Anthony P. Adamis, Emmett T. Cunningham et al. · New England Journal of Medicine | 29 Dec 2004 | 2,343 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.