Topic · 14-3-3 protein interactions
Most cited papers in 14-3-3 protein interactions
What are the most cited papers in 14-3-3 protein interactions?
The most cited paper in 14-3-3 protein interactions is "AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint" (Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al., 2008), with 3,881 citations. Next come "Promotion of microtubule assembly in vitro by taxol" (3,631) and "Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF" (2,841).
Showing 50 of 100 papers. Every paper with more than 659 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell | Apr 2008 | 3,881 |
| 2 | Promotion of microtubule assembly in vitro by taxol Peter B. Schiff, Jane Fant, Susan Band Horwitz · Nature | Feb 1979 | 3,631 |
| 3 | Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF Paul Wan, Mathew J. Garnett, Stephen Mark Roe et al. · Cell | Mar 2004 | 2,841 |
| 4 | Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL Jiping Zha, Hisashi Harada, Elizabeth Yang et al. · Cell | Nov 1996 | 2,633 |
| 5 | Signaling—2000 and Beyond Tony R. Hunter · Cell | 2000 | 2,597 |
| 6 | Comprehensive analysis of kinase inhibitor selectivity Mindy I. Davis, Jeremy P. Hunt, Sanna Herrgård et al. · Nature Biotechnology | 30 Oct 2011 | 2,466 |
| 7 | Signaling Through Scaffold, Anchoring, and Adaptor Proteins Tony J. Pawson, John D. Scott · Science | 19 Dec 1997 | 2,292 |
| 8 | Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work. Luc Buée, Thierry Bussière, Valérie Buée‐Scherrer et al. · Brain Research Reviews | Aug 2000 | 2,046 |
| 9 | Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature | 1998 | 1,832 |
| 10 | Signal Transduction through MAP Kinase Cascades Timothy S. Lewis, Paul S. Shapiro, Natalie G. Ahn · Advances in cancer research | 1998 | 1,774 |
| 11 | Visualization of protein interactions in living plant cells using bimolecular fluorescence complementation Michael J. Walter, Christina Chaban, Katia Schütze et al. · The Plant Journal | 14 Sep 2004 | 1,759 |
| 12 | Microtubule-binding agents: a dynamic field of cancer therapeutics Charles Dumontet, Mary Ann Jordan · Nature Reviews Drug Discovery | Oct 2010 | 1,731 |
| 13 | Small-molecule inhibitors of protein–protein interactions: progressing towards the dream Michelle R. Arkin, James A. Wells · Nature Reviews Drug Discovery | Apr 2004 | 1,713 |
| 14 | The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity Michael B. Yaffe, Katrin Rittinger, Stefano Volinia et al. · Cell | Dec 1997 | 1,653 |
| 15 | Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain Raimond B. G. Ravelli, Benoı̂t Gigant, Patrick A. Curmi et al. · Nature | Mar 2004 | 1,643 |
| 16 | Scansite 2.0: proteome-wide prediction of cell signaling interactions using short sequence motifs John C. Obenauer · Nucleic Acids Research | 24 Jun 2003 | 1,630 |
| 17 | 14-3-3 Proteins: Structure, Function, and Regulation Haian Fu, Romesh R. Subramanian, Shane C. Masters · The Annual Review of Pharmacology and Toxicology | Apr 2000 | 1,596 |
| 18 | Regulation of the G2/M transition by p53 William R. Taylor, George Robert Stark · Oncogene | 5 Apr 2001 | 1,572 |
| 19 | DNA TOPOISOMERASES James C. Wang · Annual Review of Biochemistry | Jun 1985 | 1,542 |
| 20 | A variant associated with nicotine dependence, lung cancer and peripheral arterial disease Thorgeir Elís Thorgeirsson et al. · Nature | Apr 2008 | 1,536 |
| 21 | Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor Bruce I. Terman, Maureen Dougher-Vermazen, Miguel E. Carrion et al. · Biochemical and Biophysical Research Communications | Sep 1992 | 1,531 |
| 22 | Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes Francisca E. Reyes‐Turcu, Karen Ventii, Keith D. Wilkinson · Annual Review of Biochemistry | Jun 2009 | 1,428 |
| 23 | Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine Anthony J. Muslin, J. William Tanner, Paul M. Allen et al. · Cell | Mar 1996 | 1,415 |
| 24 | Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions Walter Kölch · Biochemical Journal | 10 Oct 2000 | 1,411 |
| 25 | MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB José A. Martina, Yong Chen, Marjan Guček et al. · Autophagy | 8 Jun 2012 | 1,410 |
| 26 | The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. Masayuki Ozawa, Hélène Baribault, Rolf Kemler · The EMBO Journal | Jun 1989 | 1,405 |
| 27 | The specificities of protein kinase inhibitors: an update Jenny Bain, Hilary McLauchlan, Matthew Elliott et al. · Biochemical Journal | 26 Mar 2003 | 1,369 |
| 28 | Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5 Laurent Meijer, Annie Borgne, Odile Mulner et al. · European Journal of Biochemistry | 1997 | 1,362 |
| 29 | A Road Map for Those Who Don't Know JAK-STAT David S. Aaronson, Curt M. Horvath · Science | 31 May 2002 | 1,351 |
| 30 | Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216 Cheng‐Yuan Peng, Paul R. Graves, Richard S. Thoma et al. · Science | 5 Sep 1997 | 1,344 |
| 31 | BES1 Accumulates in the Nucleus in Response to Brassinosteroids to Regulate Gene Expression and Promote Stem Elongation Yanhai Yin, Zhiyong Wang, Santiago Mora‐García et al. · Cell | Apr 2002 | 1,323 |
| 32 | Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25 Yolanda Sánchez, Calvin Wong, Richard S. Thoma et al. · Science | 5 Sep 1997 | 1,314 |
| 33 | Organization and regulation of mitogen-activated protein kinase signaling pathways Timothy P. Garrington, Gary L. Johnson · Current Opinion in Cell Biology | Apr 1999 | 1,291 |
| 34 | The importance of being proline: the interaction of proline‐rich motifs in signaling proteins with their cognate domains Brian K. Kay, Michael P. Williamson, Marius Sudol · The FASEB Journal | Feb 2000 | 1,227 |
| 35 | Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations Richard C. Weisenberg · Science | 22 Sep 1972 | 1,224 |
| 36 | High-Resolution Model of the Microtubule Eva Nogales, Michael Whittaker, Ronald A. Milligan et al. · Cell | 1999 | 1,212 |
| 37 | A comprehensive pathway map of epidermal growth factor receptor signaling Kanae Oda, Yukiko Matsuoka, Akira Funahashi et al. · Molecular Systems Biology | 25 May 2005 | 1,186 |
| 38 | Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown. Avram Hershko, Hannah Heller, Sarah Elias et al. · Journal of Biological Chemistry | Jul 1983 | 1,163 |
| 39 | Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor Martin Gassmann, Franca Casagranda, Donata Orioli et al. · Nature | Nov 1995 | 1,158 |
| 40 | The regulation of protein function by multisite phosphorylation – a 25 year update Philip Cohen · Trends in Biochemical Sciences | Dec 2000 | 1,145 |
| 41 | Novel anticancer targets: revisiting ERBB2 and discovering ERBB3 José Baselga, Sandra M. Swain · Nature reviews. Cancer | 18 Jun 2009 | 1,143 |
| 42 | Flexible nets A. Keith Dunker, Marc S. Cortese, Pedro R Romero et al. · FEBS Journal | Oct 2005 | 1,141 |
| 43 | Microtubules and resistance to tubulin-binding agents Maria Kavallaris · Nature reviews. Cancer | 11 Feb 2010 | 1,127 |
| 44 | Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Mary Ann Jordan, Robert J. Toso, Douglas Thrower et al. · Proceedings of the National Academy of Sciences | 15 Oct 1993 | 1,113 |
| 45 | Tyrosine hydroxylase and regulation of dopamine synthesis S. Colette Daubner, Tiffany Le, Shanzhi Wang · Archives of Biochemistry and Biophysics | 20 Dec 2010 | 1,106 |
| 46 | AKAP signalling complexes: focal points in space and time Wei Wong, John D. Scott · Nature Reviews Molecular Cell Biology | Dec 2004 | 1,095 |
| 47 | Taxol: A Novel Investigational Antimicrotubule Agent Eric Keith Rowinsky, Lorraine A. Cazenave, Ross C. Donehower · JNCI Journal of the National Cancer Institute | Aug 1990 | 1,094 |
| 48 | A chemical switch for inhibitor-sensitive alleles of any protein kinase Anthony C. Bishop, Jeffrey A. Ubersax, Dejah T. Petsch et al. · Nature | Sep 2000 | 1,071 |
| 49 | TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation Jeong‐Ho Hong, Eun Sook Hwang, Michael T. McManus et al. · Science | 11 Aug 2005 | 1,036 |
| 50 | Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. Giuseppe Bunone, P. A. Briand, Richard J. Miksicek et al. · The EMBO Journal | May 1996 | 996 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.