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Topic · Acute Ischemic Stroke Management

Most cited papers in Acute Ischemic Stroke Management

Acute Ischemic Stroke Management

What are the most cited papers in Acute Ischemic Stroke Management?

The most cited paper in Acute Ischemic Stroke Management is "Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment." (Harold P. Adams, Birgitte H. Bendixen, L. Jaap Kappelle et al., 1993), with 12,468 citations. Next come "Correspondence - Tranexamic acid for traumatic brain injury" (11,912) and "Tissue Plasminogen Activator for Acute Ischemic Stroke" (11,752).

Showing 50 of 100 papers. Every paper with more than 1,721 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Harold P. Adams, Birgitte H. Bendixen, L. Jaap Kappelle et al. · Stroke Open access 1993 12,468
2 Correspondence - Tranexamic acid for traumatic brain injury Marina Romanello et al. · London School of Economics and Political Science Theses Online (London School of Economics and Political Science) Open access 2005 11,912
3 Tissue Plasminogen Activator for Acute Ischemic Stroke The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study G · New England Journal of Medicine 14 Dec 1995 11,752
4 Aspirin plus Clopidogrel as Secondary Prevention after Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis Qinghua Zhang, Chao Wang, Maoyong Zheng et al. · Cerebrovascular Diseases ReviewOpen access 24 Dec 2014 11,556
5 Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation Manesh R. Patel, Kenneth W. Mahaffey, Jyotsna Garg et al. · New England Journal of Medicine Open access 10 Aug 2011 9,484
6 Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Dariush Mozaffarian et al. · PubMed 27 Jan 2015 8,335
7 Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 Valery L. Feigin et al. · The Lancet Neurology Open access417 authors 3 Sep 2021 8,093
8 Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials Mayank Goyal et al. · The Lancet Review 20 Feb 2016 7,859
9 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Edward C. Jauch, Jeffrey L. Saver, Harold P. Adams et al. · Stroke Open access Feb 2013 7,675
10 Reversible middle cerebral artery occlusion without craniectomy in rats. Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke Open access 1989 7,562
11 Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach Gregory Y.H. Lip, Robby Nieuwlaat, Ron Pisters et al. · CHEST Journal Open access 18 Sep 2009 6,816
12 Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke Werner Hacke, Markku Kaste, Erich Bluhmki et al. · New England Journal of Medicine Open access 24 Sep 2008 6,735
13 A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke Olvert A. Berkhemer et al. · New England Journal of Medicine Open access 17 Dec 2014 6,707
14 Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine MARK H. ZWEIG, Gregory Campbell · Clinical Chemistry Apr 1993 6,656
15 Interobserver agreement for the assessment of handicap in stroke patients. John Cornelis Van Swieten, Peter J. Koudstaal, Marieke C H de Visser et al. · Stroke Open access May 1988 6,579
16 Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke Mayank Goyal et al. · New England Journal of Medicine Open access 11 Feb 2015 6,122
17 Measurements of acute cerebral infarction: a clinical examination scale. Thomas G. Brott, Harold P. Adams, Charles P. Olinger et al. · Stroke Jul 1989 5,992
18 Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection Bruce C.V. Campbell et al. · New England Journal of Medicine Open access 11 Feb 2015 5,898
19 Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 Valery L. Feigin et al. · The Lancet Neurology Open access510 authors 14 Mar 2019 5,824
20 Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct Raul G. Nogueira et al. · New England Journal of Medicine Open access 11 Nov 2017 5,684
21 Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration Joanna Marguerite Wardlaw et al. · The Lancet Neurology Open access 15 Jul 2013 5,550
22 Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke Jeffrey L. Saver et al. · New England Journal of Medicine Open access 17 Apr 2015 5,219
23 Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack Walter N. Kernan, Bruce I Ovbiagele, Henry Richard Black et al. · Stroke May 2014 5,218
24 Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials Christian Thomas Ruff, Robert Patrick Giugliano, Eugene Braunwald et al. · The Lancet Review 4 Dec 2013 5,070
25 Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging Gregory W. Albers et al. · New England Journal of Medicine Open access 30 Jan 2018 4,963
26 Vascular dementia Gustavo C. Román et al. · Neurology Feb 1993 4,937
27 Validation of Clinical Classification Schemes for Predicting Stroke Brian F. Gage, Amy D. Waterman, William D. Shannon et al. · JAMA 13 Jun 2001 4,866
28 Meta-analysis: Antithrombotic Therapy to Prevent Stroke in Patients Who Have Nonvalvular Atrial Fibrillation Robert G. Hart, Lesly A. Pearce, Maria I. Aguilar · Annals of Internal Medicine 19 Jun 2007 4,830
29 An International Randomized Trial Comparing Four Thrombolytic Strategies for Acute Myocardial Infarction The GUSTO Investigators · New England Journal of Medicine Open access 2 Sep 1993 4,083
30 Isolated Hand Paresis: A Case Series Karl Bjørnar Alstadhaug, Ane Skaare Sjulstad · Cerebrovascular Diseases Extra Open access 17 Apr 2013 4,075
31 Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010 Valery L. Feigin, Mohammad Hossein Forouzanfar, Rita Krishnamurthi et al. · The Lancet Open access 24 Oct 2013 3,977
32 Pathobiology of ischaemic stroke: an integrated view Ulrich Dirnagl, Costantino Iadecola, Michael A. Moskowitz · Trends in Neurosciences Review Sep 1999 3,943
33 Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II) Werner Hacke, Markku Kaste, Cesare Fieschi et al. · The Lancet Oct 1998 3,684
34 An Updated Definition of Stroke for the 21st Century Ralph L. Sacco, Scott Eric Kasner, Joseph P. Broderick et al. · Stroke Open access 8 May 2013 3,583
35 Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study Martin James O'Donnell et al. · The Lancet 18 Jun 2010 3,516
36 Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges Leonardo Pantoni · The Lancet Neurology 17 Jun 2010 3,452
37 Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 Catherine Owens Johnson et al. · The Lancet Neurology Open access273 authors 11 Mar 2019 3,411
38 Classification and natural history of clinically identifiable subtypes of cerebral infarction John Bamford, Peter AG Sandercock, Martin S. Dennis et al. · The Lancet Jun 1991 3,314
39 MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis Charles P Warlow · The Lancet May 1991 3,290
40 Guidelines for Adult Stroke Rehabilitation and Recovery Carolee Joyce Winstein, Joel M. Stein, Ross A Arena et al. · Stroke 5 May 2016 3,289
41 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association Dawn Kleindorfer, Amytis Towfighi, Seemant Chaturvedi et al. · Stroke Open access 24 May 2021 3,202
42 Intra-arterial Prourokinase for Acute Ischemic Stroke Anthony J. Furlan, Randall T. Higashida, Lawrence R. Wechsler et al. · JAMA Dec 1999 3,083
43 World Stroke Organization (WSO): Global Stroke Fact Sheet 2022 Valery L. Feigin, Michael Brainin, Bo Norrving et al. · International Journal of Stroke 2022 3,034
44 Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review Valery L. Feigin, Carlene M.M. Lawes, Derrick Bennett et al. · The Lancet Neurology Review 22 Feb 2009 2,885
45 Guidelines on the diagnosis and management of acute pulmonary embolism Authors/Task Force Members et al. · European Heart Journal Open access 30 Aug 2008 2,837
46 Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials Jonathan Emberson et al. · The Lancet ReviewOpen access 5 Aug 2014 2,799
47 Stroke rehabilitation Peter Langhorne, Julie A Bernhardt, Gert Kwakkel · The Lancet May 2011 2,714
48 Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis Charlotte JJ van Asch, Merel J.A. Luitse, Gabriël J.E. Rinkel et al. · The Lancet Neurology Review 6 Jan 2010 2,709
49 Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy Philip A. Barber, Andrew M. Demchuk, Jinjin Zhang et al. · The Lancet May 2000 2,683
50 Guidelines for the Primary Prevention of Stroke James F. Meschia, Cheryl Bushnell, Bernadette Boden-Albala et al. · Stroke Open access 30 Oct 2014 2,661

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.