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Most cited papers in Advanced Breast Cancer Therapies

What are the most cited papers in Advanced Breast Cancer Therapies?

The most cited paper in Advanced Breast Cancer Therapies is "Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies" (Brian David Lehmann, Joshua A. Bauer, Xi Chen et al., 2011), with 5,662 citations. Next come "Breast Cancer Treatment" (5,015) and "Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer" (4,641).

Showing 50 of 100 papers. Every paper with more than 918 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies Brian David Lehmann, Joshua A. Bauer, Xi Chen et al. · Journal of Clinical Investigation Open access 10 Jun 2011 5,662
2 Breast Cancer Treatment Adrienne Gropper Waks, Eric P. Winer · JAMA 22 Jan 2019 5,015
3 Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer Massimo Cristofanilli, George Thomas Budd, Matthew J. Ellis et al. · New England Journal of Medicine Open access 18 Aug 2004 4,641
4 Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer Peter Schmid, Sylvia Adams, Hope S. Rugo et al. · New England Journal of Medicine Open access 20 Oct 2018 4,469
5 Triple-Negative Breast Cancer William David Foulkes, Ian E. Smith, Jorge Sergio Reis-Filho · New England Journal of Medicine 10 Nov 2010 4,277
6 Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013 Aron Goldhirsch et al. · Annals of Oncology Open access 6 Aug 2013 3,776
7 Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer Charles E. Geyer, John Forster, Deborah L. Lindquist et al. · New England Journal of Medicine Open access 27 Dec 2006 3,486
8 Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation Mark E. Robson, Seock‐Ah Im, Elżbieta Senkus et al. · New England Journal of Medicine Open access 4 Jun 2017 3,322
9 Palbociclib and Letrozole in Advanced Breast Cancer Richard S. Finn, Miguel Martín, Hope S. Rugo et al. · New England Journal of Medicine 16 Nov 2016 3,059
10 Breast cancer Nadia Harbeck, Frederique Madeleine Penault-Llorca, Javier Cortés et al. · Nature Reviews Disease Primers ReviewOpen access 23 Sep 2019 3,056
11 Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer Charles L. Vogel · Journal of Clinical Oncology Feb 2002 2,953
12 Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer Kathleen N. Moore et al. · New England Journal of Medicine Open access 21 Oct 2018 2,927
13 Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer José Baselga et al. · New England Journal of Medicine Open access 7 Dec 2011 2,868
14 Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer Fabrice André, Eva M. Ciruelos, Gábor Rubovszky et al. · New England Journal of Medicine Open access 15 May 2019 2,660
15 Triple-negative breast cancer molecular subtyping and treatment progress Li Yin, Jiang-Jie Duan, Xiu-Wu Bian et al. · Breast Cancer Research Open access 9 Jun 2020 2,604
16 Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer Mansoor R. Mirza et al. · New England Journal of Medicine Open access 8 Oct 2016 2,495
17 Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer Joseph A. Sparano et al. · New England Journal of Medicine Open access 3 Jun 2018 2,447
18 Breast cancer Nadia Harbeck, Michael Gnant · The Lancet 16 Nov 2016 2,347
19 Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer Anthony Howell, Jack M. Cuzick, Michael Baum et al. · The Lancet 2005 2,295
20 Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Fátima Cardoso, Stella Kyriakides, Shinji Ohno et al. · Annals of Oncology Open access 22 May 2019 2,287
21 Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation Jennifer Keating Litton, Hope S. Rugo, Johannes Ettl et al. · New England Journal of Medicine Open access 15 Aug 2018 2,198
22 Pertuzumab, Trastuzumab, and Docetaxel in HER2-Positive Metastatic Breast Cancer Sandra M. Swain, José Baselga, Sung‐Bae Kim et al. · New England Journal of Medicine Open access 18 Feb 2015 2,183
23 Cyclins and cancer II: Cyclin D and CDK inhibitors come of age Tony R. Hunter, Jonathon Pines · Cell Nov 1994 2,119
24 PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer Antonino Glaviano et al. · Molecular Cancer Open access 18 Aug 2023 2,108
25 3rd ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 3) Fátima Cardoso et al. · Annals of Oncology Open access 11 Oct 2016 2,075
26 Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer Gabriel N. Hortobágyi et al. · New England Journal of Medicine Open access 8 Oct 2016 2,066
27 Risk Factors and Preventions of Breast Cancer Yi-Sheng Sun, Zhao Zhao, Zhang-Nv Yang et al. · International Journal of Biological Sciences Open access 2017 2,053
28 Breast Cancer—Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies—An Updated Review Sergiusz Łukasiewicz, Marcin Czeczelewski, Alicja Forma et al. · Cancers Open access 25 Aug 2021 1,968
29 Cell cycle proteins as promising targets in cancer therapy Tobias Otto, Piotr Siciński · Nature reviews. Cancer ReviewOpen access 27 Jan 2017 1,945
30 The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study Richard S. Finn, John P. Crown, István Láng et al. · The Lancet Oncology 15 Dec 2014 1,934
31 Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer Jonathan A. Ledermann, Philipp Harter, Charlie Gourley et al. · New England Journal of Medicine 27 Mar 2012 1,916
32 Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial Éric Pujade-Lauraine et al. · The Lancet Oncology Open access121 authors 25 Jul 2017 1,891
33 20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years Hongchao Pan, Richard G. Gray, Jeremy P. Braybrooke et al. · New England Journal of Medicine Open access 8 Nov 2017 1,883
34 Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial Massimo Cristofanilli, Nicholas C. Turner, Igor Bondarenko et al. · The Lancet Oncology Open access 2 Mar 2016 1,870
35 Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015 Alan Stuart Coates et al. · Annals of Oncology Open access 4 May 2015 1,865
36 Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial Javier Cortés et al. · The Lancet Open access227 authors Dec 2020 1,856
37 A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer Paul Edward Goss, James N. Ingle, Silvana Martino et al. · New England Journal of Medicine Open access 6 Nov 2003 1,833
38 Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics Uttpal Anand, Abhijit Dey, Arvind K. Singh Chandel et al. · Genes & Diseases Open access 18 Mar 2022 1,808
39 The history and future of targeting cyclin-dependent kinases in cancer therapy Uzma Saddia Asghar, Agnieszka Katarzyna Witkiewicz, Nicholas C. Turner et al. · Nature Reviews Drug Discovery ReviewOpen access 30 Jan 2015 1,805
40 Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction Ji Luo, Nicole L. Solimini, Stephen J. Elledge · Cell Open access Mar 2009 1,790
41 MONARCH 3: Abemaciclib As Initial Therapy for Advanced Breast Cancer Matthew Philip Goetz, Masakazu Toi, Mario Campone et al. · Journal of Clinical Oncology Open access 2 Oct 2017 1,770
42 Adjuvant Olaparib for Patients with BRCA1 - or BRCA2 -Mutated Breast Cancer Andrew N.J. Tutt et al. · New England Journal of Medicine Open access 3 Jun 2021 1,744
43 Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial Robert Louis Coleman et al. · The Lancet Open access117 authors 12 Sep 2017 1,729
44 MONARCH 2: Abemaciclib in Combination With Fulvestrant in Women With HR+/HER2− Advanced Breast Cancer Who Had Progressed While Receiving Endocrine Therapy George W. Sledge, Masakazu Toi, Patrick Neven et al. · Journal of Clinical Oncology Open access 3 Jun 2017 1,710
45 Small molecules in targeted cancer therapy: advances, challenges, and future perspectives Lei Zhong, Yueshan Li, Liang Xiong et al. · Signal Transduction and Targeted Therapy Open access 30 May 2021 1,707
46 Breast cancer Sibylle Loibl, Philip M. Poortmans, Monica Morrow et al. · The Lancet 2 Apr 2021 1,696
47 Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer Aditya Bardia et al. · New England Journal of Medicine Open access 21 Apr 2021 1,671
48 Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Elżbieta Senkus, Stella Kyriakides, Shinji Ohno et al. · Annals of Oncology Open access 27 Aug 2015 1,660
49 Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial Andrew N.J. Tutt, Mark E. Robson, Judy Ellen Garber et al. · The Lancet Jul 2010 1,660
50 Breast Cancer, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology William John Gradishar et al. · Journal of the National Comprehensive Cancer Network Apr 2020 1,628

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.