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Most cited papers in Advanced Drug Delivery Systems

What are the most cited papers in Advanced Drug Delivery Systems?

The most cited paper in Advanced Drug Delivery Systems is "Engineering precision nanoparticles for drug delivery" (Michael J. Mitchell, Margaret M. Billingsley, Rebecca M. Haley et al., 2020), with 7,854 citations. Next come "Nano based drug delivery systems: recent developments and future prospects" (6,726) and "Stimuli-responsive nanocarriers for drug delivery" (6,259).

Showing 50 of 100 papers. Every paper with more than 1,207 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Engineering precision nanoparticles for drug delivery Michael J. Mitchell, Margaret M. Billingsley, Rebecca M. Haley et al. · Nature Reviews Drug Discovery ReviewOpen access 4 Dec 2020 7,854
2 Nano based drug delivery systems: recent developments and future prospects Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto et al. · Journal of Nanobiotechnology Open access 19 Sep 2018 6,726
3 Stimuli-responsive nanocarriers for drug delivery Simona Mura, Julien Nicolas, Patrick Couvreur · Nature Materials 23 Oct 2013 6,259
4 A review of chitin and chitosan applications Majeti N. V. Ravi Kumar · Reactive and Functional Polymers Nov 2000 6,029
5 Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems M. Danaei, M. Dehghankhold, Shahla Ataei et al. · Pharmaceutics Open access 18 May 2018 4,847
6 Designing hydrogels for controlled drug delivery Jianyu Li, David J. Mooney · Nature Reviews Materials ReviewOpen access 18 Oct 2016 4,836
7 Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier Hirenkumar K. Makadia, Steven J. Siegel · Polymers Open access 26 Aug 2011 4,766
8 Drug Delivery Systems: Entering the Mainstream Theresa M. Allen, Pieter R. Cullis · Science 19 Mar 2004 4,545
9 PEGylation as a strategy for improving nanoparticle-based drug and gene delivery Jung Soo Suk, Qingguo Xu, Nam‐Ho Kim et al. · Advanced Drug Delivery Reviews ReviewOpen access 19 Oct 2015 4,511
10 Environment-sensitive hydrogels for drug delivery Yong Qiu, Kinam Park · Advanced Drug Delivery Reviews Review Dec 2001 3,907
11 PLGA-based nanoparticles: An overview of biomedical applications Fabienne Danhier, Eduardo Ansorena, Joana M. Silva et al. · Journal of Controlled Release 4 Feb 2012 3,807
12 Hydrogels in drug delivery: Progress and challenges Todd R. Hoare, Daniel S. Kohane · Polymer Open access 21 Jan 2008 3,776
13 Biodegradable polymeric nanoparticles based drug delivery systems Avnesh Kumari, Sudesh Kumar Yadav, Subhash Chandra Yadav · Colloids and Surfaces B Biointerfaces Open access 9 Sep 2009 3,716
14 Liposome: classification, preparation, and applications Abolfazl Akbarzadeh, Rogaie Rezaei-Sadabady, Soodabeh Davaran et al. · Nanoscale Research Letters Open access 22 Feb 2013 3,634
15 Biodegradable polymeric nanoparticles as drug delivery devices Kumaresh S. Soppimath, Tejraj Malleshappa Aminabhavi, Anandrao R. Kulkarni et al. · Journal of Controlled Release 2001 3,537
16 Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives Katrin Knop, Richard Hoogenboom, Dagmar Fischer et al. · Angewandte Chemie International Edition 20 Jul 2010 3,525
17 Biodegradable nanoparticles for drug and gene delivery to cells and tissue Jayanth Panyam, Vinod D. Labhasetwar · Advanced Drug Delivery Reviews Review Feb 2003 3,364
18 Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release Nazila Kamaly, Basit Yameen, Jun Hua Wu et al. · Chemical Reviews ReviewOpen access 8 Feb 2016 3,033
19 Chitosan Chemistry and Pharmaceutical Perspectives M. N. V. Ravi Kumar, Riccardo A.A. Müzzarelli, Corrado Muzzarelli et al. · Chemical Reviews Review Dec 2004 2,949
20 Biodegradable Long-Circulating Polymeric Nanospheres Ruxandra Gref, Yoshiharu Minamitake, Maria Teresa Peracchia et al. · Science 18 Mar 1994 2,919
21 Chitosan—A versatile semi-synthetic polymer in biomedical applications Mamoni Dash, Emo Chiellini, Raphael M. Ottenbrite et al. · Progress in Polymer Science 23 Feb 2011 2,889
22 Nanoparticle-based targeted drug delivery Rajesh Singh, James W. Lillard · Experimental and Molecular Pathology Open access 8 Jan 2009 2,747
23 Polymeric Systems for Controlled Drug Release Kathryn E. Uhrich, Scott M. Cannizzaro, Róbert Langer et al. · Chemical Reviews Review 26 Oct 1999 2,625
24 Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles Chunbai He, Yiping Hu, Lichen Yin et al. · Biomaterials 9 Feb 2010 2,616
25 Recent advances on chitosan-based micro- and nanoparticles in drug delivery Sunil A. Agnihotri, Mallikarjuna N. Nadagouda, Tejraj Malleshappa Aminabhavi · Journal of Controlled Release 30 Sep 2004 2,582
26 Chitosan-based hydrogels for controlled, localized drug delivery Narayan Raj Bhattarai, Jonathan Gunn, Miqin Zhang · Advanced Drug Delivery Reviews Review Oct 2009 2,455
27 Liposomes as nanomedical devices Giuseppina Bozzuto, Agnese Molinari · International Journal of Nanomedicine Open access Feb 2015 2,263
28 Lipid NanoparticlesFrom Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement Rumiana Tenchov, Robert E. Bird, Allison E. Curtze et al. · ACS Nano Open access 28 Jun 2021 2,221
29 Liposomal Formulations in Clinical Use: An Updated Review Upendra Bulbake, Sindhu Doppalapudi, Nagavendra Kommineni et al. · Pharmaceutics Open access 27 Mar 2017 2,147
30 Hydrogel nanoparticles in drug delivery Mehrdad Hamidi, Amir Azadi, Pedram Rafiei · Advanced Drug Delivery Reviews Review 21 Sep 2008 2,068
31 Drug Solubility: Importance and Enhancement Techniques Ketan T. Savjani, Anuradha Ketan Gajjar, Jignasa Savjani · ISRN Pharmaceutics Open access 5 Jul 2012 2,013
32 Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan — a review Meera George, T. Emilia Abraham · Journal of Controlled Release 23 May 2006 2,003
33 Cyclodextrin-based pharmaceutics: past, present and future Mark E. Davis, Marcus Eli Brewster · Nature Reviews Drug Discovery Review Dec 2004 1,994
34 Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells Per Artursson, Johan E. Karlsson · Biochemical and Biophysical Research Communications Mar 1991 1,896
35 Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates Vasco Filipe, Andrea Hawe, Wim Jiskoot · Pharmaceutical Research Open access 3 Mar 2010 1,871
36 Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers Pilar Calvo, C. Remu��n-L�pez, J. L. Vila-Jato et al. · Journal of Applied Polymer Science 3 Jan 1997 1,869
37 Hydrogels: from controlled release to pH-responsive drug delivery Piyush Gupta, Kavita Vermani, Sanjay Garg · Drug Discovery Today May 2002 1,824
38 Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues Samuel K. Lai, Yingying Wang, Justin S. Hanes · Advanced Drug Delivery Reviews ReviewOpen access 14 Dec 2008 1,815
39 On the importance and mechanisms of burst release in matrix-controlled drug delivery systems Xiao Bing Huang, Christopher S. Brazel · Journal of Controlled Release Jun 2001 1,806
40 Pharmaceutical Applications of Solid Dispersion Systems Win Loung Chiou, Sidney Riegelman · Journal of Pharmaceutical Sciences Sep 1971 1,795
41 Hydrogels in controlled release formulations: Network design and mathematical modeling Chien‐Chi Lin, Andrew T. Metters · Advanced Drug Delivery Reviews Review 23 Sep 2006 1,773
42 Microneedles for drug and vaccine delivery Yeu‐Chun Kim, Jung‐Hwan Park, Mark R. Prausnitz · Advanced Drug Delivery Reviews ReviewOpen access May 2012 1,758
43 Penetration enhancers Adrian C. Williams, Brian William. Barry · Advanced Drug Delivery Reviews Review 22 Dec 2003 1,740
44 Chitosan: An Overview of Its Properties and Applications Inmaculada Aranaz, Andrés R. Alcántara, Concepción Civera et al. · Polymers Open access 24 Sep 2021 1,737
45 Polysaccharides-based nanoparticles as drug delivery systems Zonghua Liu, Yanpeng Jiao, Yifei Wang et al. · Advanced Drug Delivery Reviews Review 18 Sep 2008 1,734
46 Controlled Drug Delivery Systems: Current Status and Future Directions Shivakalyani Adepu, Seeram Ramakrishna · Molecules Open access 29 Sep 2021 1,730
47 Targeted polymeric therapeutic nanoparticles: design, development and clinical translation Nazila Kamaly, Zeyu Xiao, Pedro M. Valencia et al. · Chemical Society Reviews ReviewOpen access 2012 1,729
48 ‘Stealth’ corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption Ruxandra Gref, Martín Luck, P. Quellec et al. · Colloids and Surfaces B Biointerfaces Oct 2000 1,727
49 Polymer-based nanocapsules for drug delivery Claudia Elizabeth Mora‐Huertas, Hatem Fessi, Abdelhamid Elaı̈ssari · International Journal of Pharmaceutics 14 Oct 2009 1,720
50 A Mesoporous Silica Nanosphere-Based Carrier System with Chemically Removable CdS Nanoparticle Caps for Stimuli-Responsive Controlled Release of Neurotransmitters and Drug Molecules Cheng‐Yu Lai, Brian G. Trewyn, Dušan M. Jeftinija et al. · Journal of the American Chemical Society 20 Mar 2003 1,672

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.