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Most cited papers in Andrographolide Research and Applications

Andrographolide Research and Applications

What are the most cited papers in Andrographolide Research and Applications?

The most cited paper in Andrographolide Research and Applications is "Cutting Edge: Inflammatory Responses Can Be Triggered by TREM-1, a Novel Receptor Expressed on Neutrophils and Monocytes" (Axel Bouchon, Jes Dietrich, Marco Colonna, 2000), with 1,310 citations. Next come "Atherosclerosis: process, indicators, risk factors and new hopes." (825) and "Salidroside Attenuates Ventilation Induced Lung Injury via SIRT1-Dependent Inhibition of NLRP3 Inflammasome." (821).

Showing 50 of 100 papers. Every paper with more than 174 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Cutting Edge: Inflammatory Responses Can Be Triggered by TREM-1, a Novel Receptor Expressed on Neutrophils and Monocytes Axel Bouchon, Jes Dietrich, Marco Colonna · The Journal of Immunology May 2000 1,310
2 Atherosclerosis: process, indicators, risk factors and new hopes. Mahmoud Rafieian‐Kopaei, Mahbubeh Setorki, Monir Doudi et al. · PubMed Open access Aug 2014 825
3 Salidroside Attenuates Ventilation Induced Lung Injury via SIRT1-Dependent Inhibition of NLRP3 Inflammasome. Yan Wang, Chu-Fan Xu, Yu-Jian Liu et al. · PubMed 2017 821
4 Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Lakshmi-Chandra Mishra, Betsy B Singh, Simon Dagenais · PubMed Aug 2000 779
5 Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2) Runfeng Li, Hou Yunlong, Huang Jicheng et al. · Pharmacological Research Open access 20 Mar 2020 686
6 Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine Mohammad Hossein Mirjalili, Elisabeth Moyano, Mercedes Bonfill et al. · Molecules Open access 3 Jul 2009 647
7 Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy Jumin Huang et al. · Gut Open access 18 May 2021 535
8 Anticancer and immunostimulatory compounds from Andrographis paniculata R. Ajaya Kumar, K Sridevi, Nitin Kumar et al. · Journal of Ethnopharmacology 13 May 2004 531
9 In silico screening of Chinese herbal medicines with the potential to directly inhibit 2019 novel coronavirus Denghai Zhang, Kun-lun Wu, Xue Zhang et al. · Journal of Chinese Integrative Medicine Open access 19 Feb 2020 498
10 Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations Jun Tang, Yibin Feng, Sai‐Wah Tsao et al. · Journal of Ethnopharmacology Open access 16 Aug 2009 490
11 Aloe vera: a systematic review of its clinical effectiveness. BK Vogler, E Ernst · PubMed ReviewOpen access Oct 1999 473
12 Macrophage M1/M2 polarization and rheumatoid arthritis: A systematic review Samuele Tardito, Giulia Benedetta Martinelli, Stefano Soldano et al. · Autoimmunity Reviews Review 11 Sep 2019 453
13 Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials Ibrahim Jantan, Waqas Ahmad, Syed Nasir Abbas Bukhari · Frontiers in Plant Science Open access 25 Aug 2015 413
14 Immunostimulant Agents from Andrographis paniculata Anju Puri, R. K. Saxena, Rachna Saxena et al. · Journal of Natural Products Jul 1993 412
15 Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach Sukanth Kumar Enmozhi, Kavitha Raja, Irudhayasamy Sebastine et al. · Journal of Biomolecular Structure and Dynamics Open access 24 Apr 2020 401
16 Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian) Wen‐Wan Chao, Bi‐Fong Lin · Chinese Medicine Open access 2010 399
17 Andrographolide Attenuates Inflammation by Inhibition of NF-κB Activation through Covalent Modification of Reduced Cysteine 62 of p50 Yi-Feng Xia, Bu-Qing Ye, Yi-Dan Li et al. · The Journal of Immunology Open access Sep 2004 380
18 In vitro alpha-glucosidase and alpha-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide. Rammohan Subramanian, Mohd Zaini Asmawi, Amirin Sadikun · Acta Biochimica Polonica Open access 29 May 2008 365
19 Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice Nicklas Raun Jacobsen, Peter Möller, Keld Alstrup Jensen et al. · Particle and Fibre Toxicology Open access 12 Jan 2009 362
20 Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti‐inflammatory effect Yuh‐Chiang Shen, Chieh‐Fu Chen, Wen‐Fei Chiou · British Journal of Pharmacology Open access 2002 359
21 Andrographis paniculata (Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology Md. Sanower Hossain, Zannat Urbi, Abubakar Sule et al. · The Scientific World JOURNAL Open access 2014 346
22 Overview of pharmacological activities of Andrographis paniculata and its major compound andrographolide Yan Dai, Shaoru Chen, Ling Chai et al. · Critical Reviews in Food Science and Nutrition 24 Jul 2018 325
23 Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata Sriram Rajagopal, R. Ajaya Kumar, Dhanvanthri S. Deevi et al. · Journal of Experimental Therapeutics and Oncology May 2003 319
24 The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo J Górski · Clinical Pharmacology & Therapeutics 2004 308
25 Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide Thanasekaran Jayakumar, Cheng-Ying Hsieh, Jie-Jen Lee et al. · Evidence-based Complementary and Alternative Medicine Open access 2013 300
26 Green synthesis of silver nanoparticles from medicinal plants and evaluation of their antiviral potential against chikungunya virus Vikrant Sharma, Sulochana Kaushik, Sulochana Kaushik et al. · Applied Microbiology and Biotechnology 9 Nov 2018 290
27 Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology Agbonlahor Okhuarobo, Joyce Ehizogie Falodun, Osayemwenre Erharuyi et al. · Asian Pacific Journal of Tropical Disease Open access 23 Feb 2014 290
28 Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells Dong Joon Kim, Jung Min, Min Seong Jang et al. · Biomolecules Open access 4 Nov 2019 289
29 Cell Differentiation-Inducing Diterpenes from Andrographis paniculata NEES. Takakuni MATSUDA, Masanori Kuroyanagi, Satoko SUGIYAMA et al. · Chemical and Pharmaceutical Bulletin Open access 1994 289
30 Green approach for synthesis of zinc oxide nanoparticles from Andrographis paniculata leaf extract and evaluation of their antioxidant, anti-diabetic, and anti-inflammatory activities Govindasamy Rajakumar, Muthu Thiruvengadam, Mydhili Govindarasu et al. · Bioprocess and Biosystems Engineering 15 Sep 2017 279
31 Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis Yuan Wang, Shujing Chen, Kunze Du et al. · Journal of Ethnopharmacology 29 Jun 2021 270
32 Andrographis paniculata: a review of pharmacological activities and clinical effects. Shahid Akbar · PubMed Mar 2011 269
33 Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer Jonathan Chee Woei Lim, Tze Khee Chan, David S.W. Ng et al. · Clinical and Experimental Pharmacology and Physiology 21 Oct 2011 268
34 Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats. Amein K. Al‐Ali, A. Aziz. M. Alkhawajah, Mohammad Akram Randhawa et al. · PubMed 11 Aug 2009 267
35 Herbal medicine and pattern identification for treating COVID-19: a rapid review of guidelines Lin Ang, Hye Won Lee, Jun‐Yong Choi et al. · Integrative Medicine Research Open access 29 Mar 2020 263
36 Hepatoprotective activity of andrographolide from Andrographis paniculata against carbontetrachloride. Sukhdev Swami Handa, Anupam Sharma · PubMed Aug 1990 262
37 Current Perspectives in the Application of Medicinal Plants Against Cancer: Novel Therapeutic Agents Sevgi Gezici, Nazım Şekeroğlu · Anti-Cancer Agents in Medicinal Chemistry 9 Jan 2019 261
38 Pharmacological Aspects of Andrographis paniculata on Health and Its Major Diterpenoid Constituent Andrographolide Kanokwan Jarukamjorn, Nobuo Nemoto · Eisei kagaku Open access 2008 259
39 Search for Natural Products Related to Regeneration of the Neuronal Network Chihiro Tohda, Tomoharu Kuboyama, Katsuko Komatsu · Neurosignals 2005 258
40 Applications of Phyto-Nanotechnology for the Treatment of Neurodegenerative Disorders Tanima Bhattacharya, Giselle A. Borges e Soares, Hitesh Chopra et al. · Materials Open access 21 Jan 2022 257
41 Altered microRNA expression profile with miR-146a upregulation in CD4+T cells from patients with rheumatoid arthritis Jingyi Li, Ying Wan, Qiuye Guo et al. · Arthritis Research & Therapy Open access 11 May 2010 256
42 Medicinal and Therapeutic Potential of Herbs and Plant Metabolites / Extracts Countering Viral Pathogens - Current Knowledge and Future Prospects Kuldeep Dhama, Kumaragurubaran Karthik, Rekha Khandia et al. · Current Drug Metabolism 30 Jan 2018 247
43 Network Pharmacology Prediction and Molecular Docking-Based Strategy to Discover the Potential Pharmacological Mechanism of Huai Hua San Against Ulcerative Colitis Jiaqin Liu, Jian Liu, Xiaoliang Tong et al. · Drug Design Development and Therapy Open access Jul 2021 243
44 Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy Md. Sanower Hossain, Zannat Urbi, Hidayah Karuniawati et al. · Life Open access 16 Apr 2021 242
45 Antihyperglycaemic And Anti‐Oxidant Properties Of Andrographis Paniculata In Normal And Diabetic Rats Xiang‐Fan Zhang, Benny Kwong‐Huat Tan · Clinical and Experimental Pharmacology and Physiology May 2000 240
46 Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata Aruna Kapil, Indu Bala KOUL, Sagarika Banerjee et al. · Biochemical Pharmacology Jul 1993 240
47 Molecular insight in the multifunctional activities of Withaferin A Wim Vanden Berghe, Linde Sabbe, Mary Kaileh et al. · Biochemical Pharmacology 6 Sep 2012 239
48 Antimicrobial activity of Andrographis paniculata Prajjal Kanti Singha, Somenath Roy, Suman Kr Dey · Fitoterapia 3 Sep 2003 235
49 Androgen Receptor– and E2F-1–Targeted Thymoquinone Therapy for Hormone-Refractory Prostate Cancer Ahmed Omar Kaseb, Kannagi Chinnakannu, Di Chen et al. · Cancer Research 15 Aug 2007 233
50 A Novel Antiinflammatory Role for Andrographolide in Asthma via Inhibition of the Nuclear Factor-κB Pathway Zhang Bao, Shouping Guan, Cheng Kuei Chang et al. · American Journal of Respiratory and Critical Care Medicine 7 Feb 2009 233

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.