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Most cited papers in Anesthesia and Sedative Agents

What are the most cited papers in Anesthesia and Sedative Agents?

The most cited paper in Anesthesia and Sedative Agents is "The Richmond Agitation–Sedation Scale: Validity and Reliability in Adult Intensive Care Unit Patients" (Curtis N. Sessler, Mark S. Gosnell, Mary Jo Grap et al., 2002), with 3,776 citations. Next come "Controlled Sedation with Alphaxalone-Alphadolone" (2,925) and "Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome" (2,470).

Showing 50 of 100 papers. Every paper with more than 708 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The Richmond Agitation–Sedation Scale: Validity and Reliability in Adult Intensive Care Unit Patients Curtis N. Sessler, Mark S. Gosnell, Mary Jo Grap et al. · American Journal of Respiratory and Critical Care Medicine Nov 2002 3,776
2 Controlled Sedation with Alphaxalone-Alphadolone Michael A. E. Ramsay, T.M. Savege, B. R. J. Simpson et al. · BMJ Open access 22 Jun 1974 2,925
3 Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome Laurent Papazian, Jean-Marie Forel, Arnaud Gacouin et al. · New England Journal of Medicine Open access 15 Sep 2010 2,470
4 Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 1: Anaesthesia Tim M. Cook, N.M. Woodall, Chris Frerk · British Journal of Anaesthesia Open access 29 Mar 2011 2,397
5 STOP Questionnaire Frances F. Chung, Balaji Yegneswaran, Pu Liao et al. · Anesthesiology 17 Apr 2008 2,356
6 Anesthesiology Richard A. Wiklund, Stanley H. Rosenbaum · New England Journal of Medicine 16 Oct 1997 2,161
7 Delirium in Older Persons Sharon K. Inouye · New England Journal of Medicine Open access 15 Mar 2006 2,106
8 Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits Vesna Jevtović‐Todorović, Richard E. Hartman, Yukitoshi Izumi et al. · Journal of Neuroscience Open access Feb 2003 2,004
9 Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists An Updated Report by the American Society of Anesthesiologists Task Force on Sed · Anesthesiology Open access Apr 2002 1,960
10 Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult Judith Jacobi, Gilles L. Fraser, Douglas B. Coursin et al. · Critical Care Medicine 2002 1,905
11 Molecular and cellular mechanisms of general anaesthesia Nicholas P. Franks, W.R. Lieb · Nature 17 Feb 1994 1,830
12 Postoperative Nausea and Vomiting Mehernoor F. Watcha, Paul F. White · Anesthesiology Open access Jul 1992 1,767
13 Monitoring Sedation Status Over Time in ICU Patients E. Wesley Ely, Brenda Truman, Ayumi Shintani et al. · JAMA 10 Jun 2003 1,734
14 Dexmedetomidine vs Midazolam for Sedation of Critically Ill Patients A Randomized Trial Richard R. Riker · JAMA 2 Feb 2009 1,682
15 A Primer for EEG Signal Processing in Anesthesia Ira Jay Rampil · Anesthesiology Open access Oct 1998 1,529
16 Intensive Care Delirium Screening Checklist: evaluation of a new screening tool Nicolas Bergeron, M. J. Dubois, M Dumont et al. · Intensive Care Medicine 20 Apr 2001 1,508
17 Ketamine—Its Pharmacology and Therapeutic Uses Paul F. White, Walter L. Way, Anthony J. Trevor · Anesthesiology Feb 1982 1,507
18 Consensus Guidelines for the Management of Postoperative Nausea and Vomiting Tong Joo Gan, Pierre Auguste Diemunsch, Ashraf Samir Habib et al. · Anesthesia & Analgesia Open access 20 Dec 2013 1,505
19 Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017 Christoph Hiemke et al. · Pharmacopsychiatry Open access 14 Sep 2017 1,453
20 Effect of Sedation With Dexmedetomidine vs Lorazepam on Acute Brain Dysfunction in Mechanically Ventilated Patients Pratik P. Pandharipande, Brenda Truman Pun, Daniel Herr et al. · JAMA 11 Dec 2007 1,452
21 The Effects of Increasing Plasma Concentrations of Dexmedetomidine in Humans Thomas J. Ebert, Judith Hall, Jill A. Barney et al. · Anesthesiology Open access Aug 2000 1,407
22 General Anesthesia, Sleep, and Coma Emery N. Brown, Ralph Lydic, Nicholas D. Schiff · New England Journal of Medicine Open access 29 Dec 2010 1,378
23 International Consensus Study of Antipsychotic Dosing David Martin Gardner, Andrea Lynn Murphy, Heather C. O’Donnell et al. · American Journal of Psychiatry Apr 2010 1,324
24 Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial Paul Stewart Myles, Kate Leslie, John J. McNeil et al. · The Lancet May 2004 1,319
25 Bispectral Analysis Measures Sedation and Memory Effects of Propofol, Midazolam, Isoflurane, and Alfentanil in Healthy Volunteers Peter S. A. Glass, Marc J. Bloom, Lee A. Kearse et al. · Anesthesiology Apr 1997 1,304
26 Consciousness and Anesthesia Michael T. Alkire, Anthony G. Hudetz, Giulio Tononi · Science Open access 6 Nov 2008 1,284
27 Validity and Reliability of the Observer??s DORIS A. CHERNIK, Dennis B. Gillings, HARRIET LAINE et al. · Journal of Clinical Psychopharmacology Aug 1990 1,262
28 Lorazepam Is an Independent Risk Factor for Transitioning to Delirium in Intensive Care Unit Patients Pratik P. Pandharipande, Ayumi Shintani, Josh F. Peterson et al. · Anesthesiology Open access 22 Dec 2005 1,258
29 Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine Maud A. S. Weerink, Michel M. R. F. Struys, Laura N. Hannivoort et al. · Clinical Pharmacokinetics Open access 19 Jan 2017 1,245
30 Delirium Jo Ellen Wilson, Matthew F. Mart, Colm M. Cunningham et al. · Nature Reviews Disease Primers ReviewOpen access 12 Nov 2020 1,244
31 Influence of Age and Gender on the Pharmacokinetics and Pharmacodynamics of Remifentanil Charles F. Minto, Thomas W. Schnider, Talmage D. Egan et al. · Anesthesiology Open access 1997 1,221
32 Occurrence and outcome of delirium in medical in-patients: a systematic literature review Najma Siddiqi, Allan O. House, John D. Holmes · Age and Ageing Review 28 Apr 2006 1,214
33 PHARMACOKINETIC MODEL DRIVEN INFUSION OF PROPOFOL IN CHILDREN Bret Marsh, Martin White, Neil S. Morton et al. · British Journal of Anaesthesia Open access Jul 1991 1,191
34 Delirium in Hospitalized Older Adults Edward R. Marcantonio · New England Journal of Medicine Open access 11 Oct 2017 1,181
35 The Influence of Method of Administration and Covariates on the Pharmacokinetics of Propofol in Adult Volunteers Thomas W. Schnider, Charles F. Minto, Pedro L. Gambús et al. · Anesthesiology May 1998 1,177
36 Understanding the Dose-Effect Relationship Nicholas H. G. Holford, Lewis B. Sheiner · Clinical Pharmacokinetics Open access 1981 1,150
37 European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium César Aldecoa, Gabriella Bettelli, Federico Bilotta et al. · European Journal of Anaesthesiology Open access 9 Feb 2017 1,143
38 Long-Term Cognitive Impairment After Critical Illness Pratik P. Pandharipande, Timothy D. Girard, James C. Jackson et al. · Survey of Anesthesiology 23 Sep 2014 1,129
39 Sedative, Amnestic, and Analgesic Properties of Small-Dose Dexmedetomidine Infusions Judith Hall, Toni D. Uhrich, Jill A. Barney et al. · Anesthesia & Analgesia Mar 2000 1,083
40 Adverse Respiratory Events in Anesthesia: A Closed Claims Analysis Robert A. Caplan, Karen L. Posner, Richard John Ward et al. · Anesthesiology Open access May 1990 1,081
41 The Influence of Age on Propofol Pharmacodynamics Thomas W. Schnider, Charles F. Minto, Steven L. Shafer et al. · Anesthesiology Jun 1999 1,077
42 Assessing pain in critically ill sedated patients by using a behavioral pain scale Jean‐François Payen, Olivier Bru, Jean‐Luc Bosson et al. · Critical Care Medicine Dec 2001 1,056
43 Outcome of delirium in critically ill patients: systematic review and meta-analysis Jorge I. Salluh, Haopeng Wang, Eric B. Schneider et al. · BMJ ReviewOpen access 3 Jun 2015 1,048
44 Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers K Knudsen, Marie Beckman Suurküla, S. Blomberg et al. · British Journal of Anaesthesia Open access May 1997 1,033
45 Transvenous Lead Extraction: Heart Rhythm Society Expert Consensus on Facilities, Training, Indications, and Patient Management Bruce Larry Wilkoff, Charles J. Love, CHARLES L. BYRD et al. · Heart Rhythm 23 May 2009 1,027
46 Delirium in elderly adults: diagnosis, prevention and treatment Tamara G. Fong, Samir R. Tulebaev, Sharon K. Inouye · Nature Reviews Neurology ReviewOpen access Apr 2009 1,012
47 Anesthesia Awareness and the Bispectral Index Michael Simon Avidan, Lini Zhang, Beth Burnside et al. · New England Journal of Medicine Open access 12 Mar 2008 988
48 Dexmedetomidine vs Midazolam or Propofol for Sedation During Prolonged Mechanical Ventilation Stephan Matthias Jakob · JAMA 21 Mar 2012 987
49 Incidence, risk factors and consequences of ICU delirium Sébastien Ouimet, Brian P. Kavanagh, Stewart B. Gottfried et al. · Intensive Care Medicine 10 Nov 2006 984
50 Major Complications of Regional Anesthesia in France Yves Auroy, Dan Benhamou, L. Bargues et al. · Anesthesiology Nov 2002 980

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.