Most cited papers in Antimicrobial Peptides and Activities
What are the most cited papers in Antimicrobial Peptides and Activities?
The most cited paper in Antimicrobial Peptides and Activities is "Antimicrobial peptides of multicellular organisms" (MICHAEL A. ZASLOFF, 2002), with 8,479 citations. Next come "Methods for in vitro evaluating antimicrobial activity: A review" (7,292) and "Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances" (6,274).
Showing 50 of 100 papers. Every paper with more than 1,209 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Antimicrobial peptides of multicellular organisms MICHAEL A. ZASLOFF · Nature | 2002 | 8,479 |
| 2 | Methods for in vitro evaluating antimicrobial activity: A review Mounyr Balouiri, Moulay Sadiki, Saâd Ibnsouda Koraichi · Journal of Pharmaceutical Analysis | 2 Dec 2015 | 7,292 |
| 3 | Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances Irith Wiegand, Kai Hilpert, Robert E. W. Hancock · Nature Protocols | 17 Jan 2008 | 6,274 |
| 4 | Toll-Like Receptors Kiyoshi Takeda, Tsuneyasu Kaisho, Shizuo Akira · Annual Review of Immunology | 3 Mar 2003 | 6,179 |
| 5 | Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Kim A. Brogden · Nature Reviews Microbiology | 10 Feb 2005 | 5,842 |
| 6 | Exosomes: composition, biogenesis and function Clotilde Théry, Laurence Zitvogel, Sebastián Amigorena · Nature reviews. Immunology | Aug 2002 | 5,446 |
| 7 | Toll-like receptors: critical proteins linking innate and acquired immunity Shizuo Akira, Kiyoshi Takeda, Tsuneyasu Kaisho · Nature Immunology | Aug 2001 | 4,814 |
| 8 | SignalP 5.0 improves signal peptide predictions using deep neural networks José Juan Almagro Armenteros, Konstantinos D. Tsirigos, Casper Kaae Sønderby et al. · Nature Biotechnology | 18 Feb 2019 | 4,807 |
| 9 | Toll-like receptors and innate immunity Ruslan M. Medzhitov · Nature reviews. Immunology | Nov 2001 | 4,298 |
| 10 | Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies Robert E. W. Hancock, Hans‐Georg Sahl · Nature Biotechnology | Dec 2006 | 4,225 |
| 11 | Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8 Florian Heil, Hiroaki Hemmi, Hubertus Hochrein et al. · Science | 23 Feb 2004 | 3,973 |
| 12 | Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response Philip T. Liu et al. · Science | 23 Feb 2006 | 3,966 |
| 13 | Mechanisms of biofilm resistance to antimicrobial agents Thien-Fah C Mah, George A. O’Toole · Trends in Microbiology | 2001 | 3,934 |
| 14 | Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components Osamu Takeuchi, Katsuaki Hoshino, Taro Kawai et al. · Immunity | Oct 1999 | 3,391 |
| 15 | Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the Lps Gene Product Katsuaki Hoshino, Osamu Takeuchi, Taro Kawai et al. · The Journal of Immunology | Apr 1999 | 3,391 |
| 16 | LPS/TLR4 signal transduction pathway Yong‐Chen Lu, Wen‐Chen Yeh, Pamela S. Ohashi · Cytokine | 7 Mar 2008 | 3,314 |
| 17 | Materials fabrication from Bombyx mori silk fibroin Danielle N. Rockwood, Rucsanda C. Preda, Tuna Yücel et al. · Nature Protocols | 22 Sep 2011 | 3,106 |
| 18 | Defensins: antimicrobial peptides of innate immunity Tomas Ganz · Nature reviews. Immunology | Sep 2003 | 3,100 |
| 19 | A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels Chao-Ming Tsai, Carl E. Frasch · Analytical Biochemistry | 1982 | 3,100 |
| 20 | Mechanisms of Antimicrobial Peptide Action and Resistance Michael R. Yeaman, Nannette Y. Yount · Pharmacological Reviews | Mar 2003 | 3,007 |
| 21 | CpG Motifs in Bacterial DNA and Their Immune Effects Arthur M. Krieg · Annual Review of Immunology | Apr 2002 | 2,585 |
| 22 | A modified microtiter-plate test for quantification of staphylococcal biofilm formation Srdjan Stepanović, Dragana Vuković, Ivana Dakić et al. · Journal of Microbiological Methods | Apr 2000 | 2,576 |
| 23 | Peptide Antimicrobial Agents Håvard Jenssen, Pamela Hamill, Robert E. W. Hancock · Clinical Microbiology Reviews | Jul 2006 | 2,519 |
| 24 | The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex Beom Seok Park, Dong Hyun Song, Ho Min Kim et al. · Nature | Mar 2009 | 2,458 |
| 25 | APD3: the antimicrobial peptide database as a tool for research and education Guangshun Wang, Xia Li, Zhe Wang · Nucleic Acids Research | 23 Nov 2015 | 2,445 |
| 26 | Extracellular DNA Required for Bacterial Biofilm Formation Cynthia B. Whitchurch, Tim Tolker‐Nielsen, Paula C. Ragas et al. · Science | 22 Feb 2002 | 2,216 |
| 27 | Signal sequences Gunnar von Heijne · Journal of Molecular Biology | Jul 1985 | 2,186 |
| 28 | Second language acquisition and second language learning Fritz Sang · System | 1983 | 2,186 |
| 29 | Hepcidin, a Urinary Antimicrobial Peptide Synthesized in the Liver Christina H. Park, Erika V. Valore, Alan J. Waring et al. · Journal of Biological Chemistry | Mar 2001 | 2,185 |
| 30 | Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature Paul G. Arnison et al. · Natural Product Reports | 20 Nov 2012 | 2,136 |
| 31 | Therapeutic peptides: current applications and future directions Lei Wang, Nanxi Wang, Wenping Zhang et al. · Signal Transduction and Targeted Therapy | 14 Feb 2022 | 2,120 |
| 32 | The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors Adrian Ozinsky, David M. Underhill, Jason D. Fontenot et al. · Proceedings of the National Academy of Sciences | 28 Nov 2000 | 2,102 |
| 33 | Designing antimicrobial peptides: form follows function Christopher D. Fjell, Jan A. Hiss, Robert E. W. Hancock et al. · Nature Reviews Drug Discovery | 16 Dec 2011 | 2,061 |
| 34 | Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism Ranjan Sen, David Baltimore · Cell | Dec 1986 | 2,023 |
| 35 | Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. Marco Baggiolini, Andrew J. Walz, Steven L. Kunkel · Journal of Clinical Investigation | Oct 1989 | 2,002 |
| 36 | Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction Jesse C. Chow, Donna W. Young, Douglas Taylor Golenbock et al. · Journal of Biological Chemistry | Apr 1999 | 1,974 |
| 37 | Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis Peck Y. Ong, Takaaki Ohtake, Corinne Brandt et al. · New England Journal of Medicine | 9 Oct 2002 | 1,973 |
| 38 | Antimicrobial Peptides: An Emerging Category of Therapeutic Agents Margit Mahlapuu, Joakim Håkansson, Lovisa Ringstad et al. · Frontiers in Cellular and Infection Microbiology | 26 Dec 2016 | 1,971 |
| 39 | Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by α-helical antimicrobial and cell non-selective membrane-lytic peptides Yechiel Shai · Biochimica et Biophysica Acta (BBA) - Biomembranes | Dec 1999 | 1,878 |
| 40 | Targeting microbial biofilms: current and prospective therapeutic strategies Hyun Min KOO, Raymond N. Allan, Robert P. Howlin et al. · Nature Reviews Microbiology | 25 Sep 2017 | 1,820 |
| 41 | β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6 De Yang, Oleg Chertov, Svetlana N. Bykovskaia et al. · Science | 15 Oct 1999 | 1,814 |
| 42 | Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract Koichi S. Kobayashi, Mathias Chamaillard, Yasunori Ogura et al. · Science | 3 Feb 2005 | 1,777 |
| 43 | Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger Ute Römling, Michael Y. Galperin, Mark Gomelsky · Microbiology and Molecular Biology Reviews | Mar 2013 | 1,756 |
| 44 | A family of human receptors structurally related to Drosophila Toll Fernando L. Rock, Gary Hardiman, Jackie C. Timans et al. · Proceedings of the National Academy of Sciences | 20 Jan 1998 | 1,743 |
| 45 | Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria Clayton W. Hall, Thien‐Fah Mah · FEMS Microbiology Reviews | 22 Feb 2017 | 1,721 |
| 46 | Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2 Naohiro Inohara, Yasunori Ogura, Ana Fontalba et al. · Journal of Biological Chemistry | Feb 2003 | 1,711 |
| 47 | Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration HAMISH R. MICHIE, Kirk R. Manogue, David R. Spriggs et al. · New England Journal of Medicine | 9 Jun 1988 | 1,708 |
| 48 | Agents that increase the permeability of the outer membrane Martti Vaara · Microbiological Reviews | Sep 1992 | 1,705 |
| 49 | Emerging Strategies to Combat ESKAPE Pathogens in the Era of Antimicrobial Resistance: A Review Mansura S. Mulani, Ekta E. Kamble, Shital N. Kumkar et al. · Frontiers in Microbiology | Apr 2019 | 1,678 |
| 50 | Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2 Benjamin N. Gantner, Randi M. Simmons, Scott J. Canavera et al. · The Journal of Experimental Medicine | 28 Apr 2003 | 1,663 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.