Most cited papers in ATP Synthase and ATPases Research
What are the most cited papers in ATP Synthase and ATPases Research?
The most cited paper in ATP Synthase and ATPases Research is "Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation" (Matthew G. Vander Heiden, Lewis C. Cantley, Craig B. Thompson, 2009), with 16,511 citations. Next come "cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination" (11,217) and "Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade" (7,307).
Showing 50 of 99 papers. Every paper with more than 1,541 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation Matthew G. Vander Heiden, Lewis C. Cantley, Craig B. Thompson · Science | 21 May 2009 | 16,511 |
| 2 | cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination Ali Punjani, John L. Rubinstein, David J. Fleet et al. · Nature Methods | 6 Feb 2017 | 11,217 |
| 3 | Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell | Nov 1997 | 7,307 |
| 4 | Targeting HIF-1 for cancer therapy Gregg L. Semenza · Nature reviews. Cancer | 16 Sep 2003 | 6,772 |
| 5 | An integrated procedure for the extraction of bacterial isoprenoid quinones and polar lipids David E. Minnikin, Anthony G. O’Donnell, Michael Goodfellow et al. · Journal of Microbiological Methods | Jul 1984 | 5,534 |
| 6 | Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release Dmitry B. Zorov, Magdalena Juhaszova, Steven J. Sollott · Physiological Reviews | Jul 2014 | 5,423 |
| 7 | The Warburg Effect: How Does it Benefit Cancer Cells? Maria V. Liberti, Jason W. Locasale · Trends in Biochemical Sciences | 5 Jan 2016 | 5,355 |
| 8 | Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold. John E. Walker, M Saraste, M J Runswick et al. · The EMBO Journal | Aug 1982 | 5,355 |
| 9 | Hypoxia — a key regulatory factor in tumour growth Adrian L. Harris · Nature reviews. Cancer | 2002 | 5,228 |
| 10 | Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked Jie Yang, Xuesong Liu, Kapil N. Bhalla et al. · Science | 21 Feb 1997 | 4,964 |
| 11 | Regulation of cancer cell metabolism Rob A. Cairns, Isaac S. Harris, Tak W. Mak · Nature reviews. Cancer | 24 Jan 2011 | 4,811 |
| 12 | Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism Peter D. Mitchell · Nature | Jul 1961 | 4,713 |
| 13 | Mitochondrial formation of reactive oxygen species Julio F. Turrens · The Journal of Physiology | 25 Aug 2003 | 4,379 |
| 14 | Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1 Zhidan Wu, Pere Puigserver, Ulf Andersson et al. · Cell | Jul 1999 | 4,156 |
| 15 | HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism | Mar 2006 | 3,976 |
| 16 | Mitochondrial Membrane Permeabilization in Cell Death Guido Kroemer, Lorenzo Galluzzi, Catherine Brenner · Physiological Reviews | 2007 | 3,622 |
| 17 | Otto Warburg's contributions to current concepts of cancer metabolism Willem Hendrik Koppenol, Patricia L. Bounds, Chi V. Dang · Nature reviews. Cancer | 14 Apr 2011 | 3,514 |
| 18 | Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition Chunying Du, Min Hui Fang, Yucheng Li et al. · Cell | Jul 2000 | 3,499 |
| 19 | Molecular dynamics simulations of biomolecules Martin Karplus, James Andrew McCammon · Nature Structural Biology | 26 Aug 2002 | 3,434 |
| 20 | The Pathophysiology of Mitochondrial Cell Death Douglas R. Green, Guido Kroemer · Science | 30 Jul 2004 | 3,411 |
| 21 | Targeting hypoxia in cancer therapy William Robert Wilson, Michael P. Hay · Nature reviews. Cancer | 24 May 2011 | 3,234 |
| 22 | Mitochondrial control of cell death Guido Kroemer, John C. Reed · Nature Medicine | May 2000 | 3,114 |
| 23 | Automated MAD and MIR structure solution Thomas C. Terwilliger, Joel Berendzen · Acta Crystallographica Section D Biological Crystallography | Apr 1999 | 3,043 |
| 24 | Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria Jan Pieter Abrahams, Andrew G. W. Leslie, René Lutter et al. · Nature | Aug 1994 | 3,039 |
| 25 | Mitochondrial TCA cycle metabolites control physiology and disease Inmaculada Martínez‐Reyes, Navdeep S. Chandel · Nature Communications | 3 Jan 2020 | 2,879 |
| 26 | Premature ageing in mice expressing defective mitochondrial DNA polymerase Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature | May 2004 | 2,779 |
| 27 | Optimal Determination of Particle Orientation, Absolute Hand, and Contrast Loss in Single-particle Electron Cryomicroscopy Peter B. Rosenthal, Richard A. Henderson · Journal of Molecular Biology | Oct 2003 | 2,705 |
| 28 | Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development Hsiuchen Chen, Scott A. Detmer, Andrew J. Ewald et al. · The Journal of Cell Biology | 13 Jan 2003 | 2,628 |
| 29 | Dynamic personalities of proteins Katherine A. Henzler‐Wildman, Dorothee Kern · Nature | 12 Dec 2007 | 2,612 |
| 30 | Calcium, ATP, and ROS: a mitochondrial love-hate triangle Paul S. Brookes, Yisang Yoon, James L. Robotham et al. · American Journal of Physiology-Cell Physiology | 8 Sep 2004 | 2,606 |
| 31 | HSP90 and the chaperoning of cancer Luke J. Whitesell, Susan Lee Lindquist · Nature reviews. Cancer | 20 Sep 2005 | 2,514 |
| 32 | Mitochondria and cancer Douglas C. Wallace · Nature reviews. Cancer | 24 Sep 2012 | 2,476 |
| 33 | Assessing mitochondrial dysfunction in cells Martin D. Brand, David G. Nicholls · Biochemical Journal | 29 Mar 2011 | 2,457 |
| 34 | Mitochondrial DNA Mutation Associated with Leber's Hereditary Optic Neuropathy Douglas C. Wallace, Gurparkash Singh, Marie T. Lott et al. · Science | 9 Dec 1988 | 2,456 |
| 35 | The mitochondrial permeability transition Mario Zoratti, Ildikò Szabó · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes | Jul 1995 | 2,419 |
| 36 | Sensors and regulators of intracellular pH Joseph R. Casey, Sergio Grinstein, John Orlowski · Nature Reviews Molecular Cell Biology | 9 Dec 2009 | 2,334 |
| 37 | HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption Ioanna Papandreou, Rob A. Cairns, Lucrezia Fontana et al. · Cell Metabolism | Mar 2006 | 2,289 |
| 38 | Dysregulated pH: a perfect storm for cancer progression Bradley A. Webb, Michael S. Chimenti, Matthew P. Jacobson et al. · Nature reviews. Cancer | 11 Aug 2011 | 2,277 |
| 39 | Direct observation of the rotation of F1-ATPase Hiroyuki Noji, Ryohei Yasuda, Masasuke Yoshida et al. · Nature | Mar 1997 | 2,260 |
| 40 | THE FUNCTION OF HEAT-SHOCK PROTEINS IN STRESS TOLERANCE: DEGRADATION AND REACTIVATION OF DAMAGED PROTEINS Dawn A. Parsell, S Lindquist · Annual Review of Genetics | Dec 1993 | 2,228 |
| 41 | Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC Shigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto et al. · Nature | 3 Jun 1999 | 2,192 |
| 42 | A Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis Koen Andries, Peter Verhasselt, Jérôme Guillemont et al. · Science | 9 Dec 2004 | 2,187 |
| 43 | ER Tubules Mark Sites of Mitochondrial Division Jonathan R. Friedman, Laura L. Lackner, Matthew West et al. · Science | Sep 2011 | 2,132 |
| 44 | Mimicking Photosynthetic Solar Energy Transduction Devens Gust, Thomas A. Moore, Ana L. Moore · Accounts of Chemical Research | 8 Nov 2000 | 2,128 |
| 45 | A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies Yu‐ichi Goto, Ikuya Nonaka, Satoshi Horai · Nature | Dec 1990 | 2,105 |
| 46 | An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9 Hua Zou, Yuchen Li, Xuesong Liu et al. · Journal of Biological Chemistry | Apr 1999 | 2,102 |
| 47 | A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson et al. · Journal of Biological Chemistry | Jul 1997 | 2,084 |
| 48 | Mitochondrial membrane potential Ljubava D. Zorova, Vasily A. Popkov, Egor Y. Plotnikov et al. · Analytical Biochemistry | 12 Jul 2017 | 2,069 |
| 49 | A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology David J. Pagliarini, Sarah E. Calvo, Betty Y Chang et al. · Cell | Jul 2008 | 2,040 |
| 50 | Mitochondrial fusion and fission in cell life and death Benedikt Westermann · Nature Reviews Molecular Cell Biology | 23 Nov 2010 | 2,034 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.