Most cited papers in Bacterial biofilms and quorum sensing
What are the most cited papers in Bacterial biofilms and quorum sensing?
The most cited paper in Bacterial biofilms and quorum sensing is "Bacterial Biofilms: A Common Cause of Persistent Infections" (John William Costerton, Philip Shook Stewart, Everett Peter Greenberg, 1999), with 12,236 citations. Next come "The biofilm matrix" (10,070) and "On the nature of allosteric transitions: A plausible model" (8,938).
Showing 50 of 100 papers. Every paper with more than 1,527 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Bacterial Biofilms: A Common Cause of Persistent Infections John William Costerton, Philip Shook Stewart, Everett Peter Greenberg · Science | 21 May 1999 | 12,236 |
| 2 | The biofilm matrix Hans‐Curt Flemming, Jost Wingender · Nature Reviews Microbiology | 2 Aug 2010 | 10,070 |
| 3 | On the nature of allosteric transitions: A plausible model Jacques Monod, Jeffries Wyman, Jean‐Pierre Changeux · Journal of Molecular Biology | May 1965 | 8,938 |
| 4 | Bacterial biofilms: from the Natural environment to infectious diseases Luanne Hall‐Stoodley, John William Costerton, Paul Stoodley · Nature Reviews Microbiology | 14 Jan 2004 | 7,252 |
| 5 | Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms Rodney M. Donlan, John William Costerton · Clinical Microbiology Reviews | Apr 2002 | 6,669 |
| 6 | Biofilms: an emergent form of bacterial life Hans‐Curt Flemming, Jost Wingender, Ulrich Szewzyk et al. · Nature Reviews Microbiology | 11 Aug 2016 | 6,029 |
| 7 | Quorum Sensing in Bacteria Melissa B. Miller, Bonnie L. Bassler · Annual Review of Microbiology | Oct 2001 | 5,167 |
| 8 | Biofilms: Microbial Life on Surfaces Rodney M. Donlan · Emerging infectious diseases | Sep 2002 | 4,917 |
| 9 | Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen C. Kendall Stover et al. · Nature | Aug 2000 | 4,698 |
| 10 | Antibiotic resistance of bacteria in biofilms Philip Shook Stewart, John William Costerton · The Lancet | Jul 2001 | 4,602 |
| 11 | MICROBIAL BIOFILMS J. W. Costerton, Zbigniew Lewandowski, Douglas E. Caldwell et al. · Annual Review of Microbiology | Oct 1995 | 4,555 |
| 12 | The antimicrobial activity of nanoparticles: present situation and prospects for the future Linlin Wang, Hu Chen, Longquan Shao · International Journal of Nanomedicine | Feb 2017 | 4,056 |
| 13 | QUORUM SENSING: Cell-to-Cell Communication in Bacteria Christopher M. Waters, Bonnie L. Bassler · Annual Review of Cell and Developmental Biology | 28 Jun 2005 | 4,030 |
| 14 | Mechanisms of biofilm resistance to antimicrobial agents Thien-Fah C Mah, George A. O’Toole · Trends in Microbiology | 2001 | 3,934 |
| 15 | Biofilm Formation as Microbial Development George A. O’Toole, Heidi B. Kaplan, Roberto Kolter · Annual Review of Microbiology | Oct 2000 | 3,596 |
| 16 | The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm David G. Davies, Matthew R. Parsek, James P. Pearson et al. · Science | 10 Apr 1998 | 3,416 |
| 17 | Acinetobacter baumannii : Emergence of a Successful Pathogen Anton Yariv Peleg, Harald Seifert, David L. Paterson · Clinical Microbiology Reviews | Jul 2008 | 3,347 |
| 18 | Antibiotic resistance of bacterial biofilms Niels Høiby, Thomas Bjarnsholt, Michael Givskov et al. · International Journal of Antimicrobial Agents | 11 Feb 2010 | 3,283 |
| 19 | Biofilms as Complex Differentiated Communities Paul Stoodley, Karin Sauer, David G. Davies et al. · Annual Review of Microbiology | 4 Sep 2002 | 3,171 |
| 20 | Microbial Biofilms: from Ecology to Molecular Genetics Mary Ellen Davey, George A. O’Toole · Microbiology and Molecular Biology Reviews | Dec 2000 | 3,115 |
| 21 | Bacterial Biofilms in Nature and Disease J. W. Costerton, K.-J. Cheng, Gill G. Geesey et al. · Annual Review of Microbiology | Oct 1987 | 3,114 |
| 22 | Multilocus Sequence Typing for Characterization of Methicillin-Resistant and Methicillin-Susceptible Clones ofStaphylococcus aureus Mark C. Enright, Nicholas Day, Catrin E. Davies et al. · Journal of Clinical Microbiology | Mar 2000 | 3,050 |
| 23 | Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators W. Claiborne Fuqua, Stephen C. Winans, Everett Peter Greenberg · Journal of Bacteriology | 1994 | 2,956 |
| 24 | Understanding biofilm resistance to antibacterial agents David G. Davies · Nature Reviews Drug Discovery | 31 Jan 2003 | 2,810 |
| 25 | Mobile Genetic Elements Associated with Antimicrobial Resistance Sally R. Partridge, Stephen Matthew Kwong, Neville Firth et al. · Clinical Microbiology Reviews | 31 Jul 2018 | 2,798 |
| 26 | Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development George A. O’Toole, Roberto Kolter · Molecular Microbiology | Oct 1998 | 2,728 |
| 27 | Klebsiella spp. as Nosocomial Pathogens: Epidemiology, Taxonomy, Typing Methods, and Pathogenicity Factors Rainer Podschun, U. Ullmann · Clinical Microbiology Reviews | Oct 1998 | 2,711 |
| 28 | Extended-Spectrum β-Lactamases in the 21st Century: Characterization, Epidemiology, and Detection of This Important Resistance Threat Patricia A. Bradford · Clinical Microbiology Reviews | Oct 2001 | 2,640 |
| 29 | A modified microtiter-plate test for quantification of staphylococcal biofilm formation Srdjan Stepanović, Dragana Vuković, Ivana Dakić et al. · Journal of Microbiological Methods | Apr 2000 | 2,576 |
| 30 | Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis George A. O’Toole, Roberto Kolter · Molecular Microbiology | Apr 1998 | 2,555 |
| 31 | Physiological heterogeneity in biofilms Philip Shook Stewart, Michael John Franklin · Nature Reviews Microbiology | 11 Feb 2008 | 2,541 |
| 32 | Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci Srdjan Stepanović, Dragana Vuković, Veronika Holá et al. · Apmis | Aug 2007 | 2,521 |
| 33 | Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks J A Kluytmans, Alex van Belkum, Henri A. Verbrugh · Clinical Microbiology Reviews | Jul 1997 | 2,500 |
| 34 | Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies Zheng Pang, Renee Raudonis, Bernard R. Glick et al. · Biotechnology Advances | 27 Nov 2018 | 2,371 |
| 35 | Federal Funding for the Study of Antimicrobial Resistance in Nosocomial Pathogens: No ESKAPE Louis B. Rice · The Journal of Infectious Diseases | 7 Mar 2008 | 2,359 |
| 36 | Quorum sensing signal–response systems in Gram-negative bacteria Kai Papenfort, Bonnie L. Bassler · Nature Reviews Microbiology | 11 Aug 2016 | 2,324 |
| 37 | Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department Gregory J. Moran, Anusha Krishnadasan, Rachel J. Gorwitz et al. · New England Journal of Medicine | 16 Aug 2006 | 2,316 |
| 38 | Implant infections: adhesion, biofilm formation and immune evasion Carla Renata Arciola, Davide Campoccia, Lucio Montanaro · Nature Reviews Microbiology | 2 May 2018 | 2,274 |
| 39 | Microtiter Dish Biofilm Formation Assay George A. O’Toole · Journal of Visualized Experiments | 30 Jan 2011 | 2,240 |
| 40 | Extracellular DNA Required for Bacterial Biofilm Formation Cynthia B. Whitchurch, Tim Tolker‐Nielsen, Paula C. Ragas et al. · Science | 22 Feb 2002 | 2,216 |
| 41 | Quantification of biofilm structures by the novel computer program comstat Arne Heydorn, Alex Toftgaard Nielsen, Morten Hentzer et al. · Microbiology | Oct 2000 | 2,211 |
| 42 | AmpC β-Lactamases George A. Jacoby · Clinical Microbiology Reviews | 2009 | 2,192 |
| 43 | The Calgary Biofilm Device: New Technology for Rapid Determination of Antibiotic Susceptibilities of Bacterial Biofilms Howard Ceri, Merle S. Olson, Carol A. Stremick et al. · Journal of Clinical Microbiology | Jun 1999 | 2,190 |
| 44 | Primary structure of the Aequorea victoria green-fluorescent protein Douglas C. Prasher, Virginia K. Eckenrode, William W. Ward et al. · Gene | Feb 1992 | 2,184 |
| 45 | Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control Steven T. Rutherford, Bonnie L. Bassler · Cold Spring Harbor Perspectives in Medicine | Nov 2012 | 2,162 |
| 46 | Biomaterial-Centered Infection: Microbial Adhesion Versus Tissue Integration Anthony G. Gristina · Science | 25 Sep 1987 | 2,160 |
| 47 | Persister cells, dormancy and infectious disease Kim Lewis · Nature Reviews Microbiology | 4 Dec 2006 | 2,099 |
| 48 | Nasal Carriage as a Source ofStaphylococcus aureusBacteremia Christof von Eiff, Karsten Becker, Konstanze Machka et al. · New England Journal of Medicine | 4 Jan 2001 | 2,026 |
| 49 | Riddle of Biofilm Resistance Kim Lewis · Antimicrobial Agents and Chemotherapy | Apr 2001 | 2,001 |
| 50 | A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants Tung Thanh Hoang, RoxAnn R. Karkhoff-Schweizer, Alecksandr J. Kutchma et al. · Gene | May 1998 | 1,992 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.