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Most cited papers in Bioactive Compounds in Plants

What are the most cited papers in Bioactive Compounds in Plants?

The most cited paper in Bioactive Compounds in Plants is "Lenalidomide plus Dexamethasone for Relapsed or Refractory Multiple Myeloma" (Meletios Athanasios Dimopoulos, Andrew G Spencer, Michael Attal et al., 2007), with 1,463 citations. Next come "Citrus flavonoids: Molecular structure, biological activity and nutritional properties: A review" (1,183) and "Update on Uses and Properties of Citrus Flavonoids: New Findings in Anticancer, Cardiovascular, and Anti-inflammatory Activity" (1,166).

Showing 50 of 100 papers. Every paper with more than 235 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Lenalidomide plus Dexamethasone for Relapsed or Refractory Multiple Myeloma Meletios Athanasios Dimopoulos, Andrew G Spencer, Michael Attal et al. · New England Journal of Medicine 21 Nov 2007 1,463
2 Citrus flavonoids: Molecular structure, biological activity and nutritional properties: A review Elisa Tripoli, Maurizio La Guardia, Santo Giammanco et al. · Food Chemistry 2007 1,183
3 Update on Uses and Properties of Citrus Flavonoids: New Findings in Anticancer, Cardiovascular, and Anti-inflammatory Activity O. Benavente-García, Jesús José André Quintana Castillo · Journal of Agricultural and Food Chemistry 2 Jul 2008 1,166
4 Analysis and design of OFDM/OQAM systems based on filterbank theory Pierre Siohan, Cyrille Siclet, Nicolas Lacaille · IEEE Transactions on Signal Processing May 2002 992
5 Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models Hamideh Parhiz, Ali Roohbakhsh, Fatemeh Soltani et al. · Phytotherapy Research 13 Nov 2014 918
6 Phase I Clinical and Pharmacokinetic Study of the Novel Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor BAY 43-9006 in Patients With Advanced Refractory Solid Tumors Dirk Strumberg, Heike Richly, Ralf Axel Hilger et al. · Journal of Clinical Oncology Open access 22 Dec 2004 876
7 Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99–06): a randomised trial Thierry T.F. Facon et al. · The Lancet Oct 2007 874
8 Autologous Transplantation and Maintenance Therapy in Multiple Myeloma Antonio Palumbo et al. · New England Journal of Medicine Open access 3 Sep 2014 786
9 Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma Bart Barlogie, Guido J. K. Tricot, Elias J. Anaissie et al. · New England Journal of Medicine 8 Mar 2006 743
10 Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer William M. Merritt et al. · New England Journal of Medicine Open access 17 Dec 2008 723
11 Phenolic composition, antioxidant potential and health benefits of citrus peel Balwinder Singh, Jatinder Pal Singh, Amritpal Kaur et al. · Food Research International 19 Feb 2020 692
12 A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone Sung‐Wuk Jang, Xia Liu, Manuel A Yepes et al. · Proceedings of the National Academy of Sciences Open access 25 Jan 2010 689
13 Antidiabetic properties of dietary flavonoids: a cellular mechanism review Ramachandran Vinayagam, Baojun Xu · Nutrition & Metabolism Open access Dec 2015 617
14 Citrus peel as a source of functional ingredient: A review Shafiya Rafiq, R. K. Kaul, Sajad Ahmad Sofi et al. · Journal of the Saudi Society of Agricultural Sciences Open access 6 Aug 2016 582
15 Effects of Flavonoids and other Polyphenols on Inflammation Raquel Muñoz-González, Isabel Ballester, Rocío López-Posadas et al. · Critical Reviews in Food Science and Nutrition 24 Mar 2011 577
16 Bioactive Compounds of Citrus Fruits: A Review of Composition and Health Benefits of Carotenoids, Flavonoids, Limonoids, and Terpenes Ramesh Kumar Saini, Arina Ranjit, Kavita Sharma et al. · Antioxidants Open access 26 Jan 2022 576
17 Biological Properties of Citrus Flavonoids Pertaining to Cancer and Inflammation John A. Manthey, Najla Guthrie, Karel Grohmann · Current Medicinal Chemistry Feb 2001 568
18 Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults Marjorie L. McCullough, Julia J. Peterson, Roshni Patel et al. · American Journal of Clinical Nutrition Open access 5 Jan 2012 539
19 A Green Tea Extract High in Catechins Reduces Body Fat and Cardiovascular Risks in Humans Tomonori Nagao, Tadashi Hase, Ichiro Tokimitsu · Obesity Open access Jun 2007 523
20 Dietary flavonoid intakes and risk of type 2 diabetes in US men and women Nicole M. Wedick, An Pan, Aedín Cassidy et al. · American Journal of Clinical Nutrition Open access 23 Feb 2012 519
21 Quercetin: potentials in the prevention and therapy of disease Stephan C. Bischoff · Current Opinion in Clinical Nutrition & Metabolic Care 29 Sep 2008 493
22 The Thrombospondins Josephine Clare Adams, Jack Lawler · Cold Spring Harbor Perspectives in Biology Open access 29 Aug 2011 486
23 A review on plant-based rutin extraction methods and its pharmacological activities Lee Suan Chua · Journal of Ethnopharmacology 30 Oct 2013 465
24 The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway Mar Larrosa, Francisco Abraham Tomás-Barberán, Juan Carlos Espı́n · The Journal of Nutritional Biochemistry 12 Oct 2005 460
25 The functions of thrombospondin-1 and-2 Jack Lawler · Current Opinion in Cell Biology Review Oct 2000 443
26 Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): results from a randomised, multicentre, open-label, phase 3 study Meletios Athanasios Dimopoulos, Hang Quach, María‐Victoria Mateos et al. · The Lancet Jul 2020 429
27 Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line Pei‐Ni Chen, Shu‐Chen Chu, Hui‐Ling Chiou et al. · Cancer Letters 23 Jun 2005 425
28 Rutin: therapeutic potential and recent advances in drug delivery Shrestha Sharma, Asgar Ali, Javed Ali et al. · Expert Opinion on Investigational Drugs 25 Jun 2013 420
29 Flavonoid composition of orange peel and its association with antioxidant and anti-inflammatory activities Xiumin Chen, Andrew R. Tait, David D. Kitts · Food Chemistry 9 Sep 2016 413
30 Anti-angiogenic, Antioxidant, and Anti-carcinogenic Properties of a Novel Anthocyanin-Rich Berry Extract Formula Debasis Bagchi, Chandan K. Sen, Manashi Bagchi et al. · Biochemistry (Moscow) 2004 405
31 Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer Arshi Malik, Farrukh Afaq, Sami Sarfaraz et al. · Proceedings of the National Academy of Sciences Open access 28 Sep 2005 402
32 Citrus polymethoxyflavones attenuate metabolic syndrome by regulating gut microbiome and amino acid metabolism Su-Ling Zeng, Shang‐Zhen Li, Ping‐Ting Xiao et al. · Science Advances Open access 3 Jan 2020 400
33 Box–Behnken design based statistical modeling for ultrasound-assisted extraction of corn silk polysaccharide Jeganathan Prakash Maran, S. Manikandan, K. Thirugnanasambandham et al. · Carbohydrate Polymers 16 Sep 2012 394
34 Flavanones: Citrus phytochemical with health‐promoting properties Davide Barreca, Giuseppe Gattuso, Ersilia Bellocco et al. · BioFactors 12 May 2017 387
35 Efficacy of Melphalan and Prednisone Plus Thalidomide in Patients Older Than 75 Years With Newly Diagnosed Multiple Myeloma: IFM 01/01 Trial Cyrille Hulin, Thierry T.F. Facon, Philippe Rodon et al. · Journal of Clinical Oncology 18 May 2009 382
36 Prospective, Randomized Study of Single Compared With Double Autologous Stem-Cell Transplantation for Multiple Myeloma: Bologna 96 Clinical Study Michèle Cavo, Patrizia Tosi, Elena Zamagni et al. · Journal of Clinical Oncology 8 May 2007 374
37 Pharmacokinetics of the citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects Feras Imad Kanaze, Melpomeni I. Bounartzi, Manolis Georgarakis et al. · European Journal of Clinical Nutrition 18 Oct 2006 372
38 Hydroxylated Polymethoxyflavones and Methylated Flavonoids in Sweet Orange ( Citrus sinensis ) Peel Shiming Li, Chih‐Yu Lo, Chi‐Tang Ho · Journal of Agricultural and Food Chemistry 16 May 2006 371
39 Antiproliferative Activities of Citrus Flavonoids against Six Human Cancer Cell Lines John A. Manthey, Najla Guthrie · Journal of Agricultural and Food Chemistry 6 Sep 2002 363
40 Health-promoting effects of the citrus flavanone hesperidin Chaoyun Li, Hermann J. Schluesener · Critical Reviews in Food Science and Nutrition 12 Feb 2015 361
41 Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health Xinmiao Lv, Siyu Zhao, Zhangchi Ning et al. · Chemistry Central Journal Open access Dec 2015 359
42 Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease Richard E. Hartman, Aartie Shah, Anne M. Fagan et al. · Neurobiology of Disease Open access 29 Sep 2006 358
43 Modern Extraction and Purification Techniques for Obtaining High Purity Food-Grade Bioactive Compounds and Value-Added Co-Products from Citrus Wastes Neelima Mahato, Mukty Sinha, Kavita Sharma et al. · Foods Open access 23 Oct 2019 351
44 Models and mechanisms of vascular dementia Poornima Venkat, Michael Chopp, Jieli Chen · Experimental Neurology Open access 21 May 2015 346
45 Citri Reticulatae Pericarpium (Chenpi): Botany, ethnopharmacology, phytochemistry, and pharmacology of a frequently used traditional Chinese medicine Xin Yu, Shuang Sun, Yuyan Guo et al. · Journal of Ethnopharmacology 6 Apr 2018 344
46 Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial Shahin Akhondzadeh, Maryam Noroozıan, M. Mohammadi et al. · Journal of Clinical Pharmacy and Therapeutics Feb 2003 343
47 17β-Estradiol Reduces Cardiomyocyte Apoptosis In Vivo and In Vitro via Activation of Phospho-Inositide-3 Kinase/Akt Signaling Richard D. Patten, Isaac Pourati, Mark J. Aronovitz et al. · Circulation Research 2 Sep 2004 335
48 Antiproliferative Activity of Flavonoids on Several Cancer Cell Lines Satoru Kawaii, Yasuhiko Tomono, Eriko Katase et al. · Bioscience Biotechnology and Biochemistry Open access 1999 334
49 Inhibitory effect of citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice. Akira Murakami, Yoshimasa Nakamura, Koji Torikai et al. · PubMed 15 Sep 2000 334
50 Citrus Polyphenol Hesperidin Stimulates Production of Nitric Oxide in Endothelial Cells while Improving Endothelial Function and Reducing Inflammatory Markers in Patients with Metabolic Syndrome Stefano Rizza, Ranganath Muniyappa, Micaela Iantorno et al. · The Journal of Clinical Endocrinology & Metabolism Open access 23 Feb 2011 325

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.