Most cited papers in Bioactive Natural Diterpenoids Research
What are the most cited papers in Bioactive Natural Diterpenoids Research?
The most cited paper in Bioactive Natural Diterpenoids Research is "Brine Shrimp: A Convenient General Bioassay for Active Plant Constituents" (Brian F. Meyer, N. R. Ferrigni, J. E. Putnam et al., 1982), with 4,843 citations. Next come "Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB" (736) and "Synopsis of the plants known as medicinal and poisonous in Northeast of Brazil" (664).
Showing 50 of 100 papers. Every paper with more than 167 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Brine Shrimp: A Convenient General Bioassay for Active Plant Constituents Brian F. Meyer, N. R. Ferrigni, J. E. Putnam et al. · Planta Medica | May 1982 | 4,843 |
| 2 | Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB Naohiro Inohara, Takeyoshi Koseki, Luis del Peso et al. · Journal of Biological Chemistry | May 1999 | 736 |
| 3 | Synopsis of the plants known as medicinal and poisonous in Northeast of Brazil Maria de Fátima Agra, Patrícia França de Freitas, José Maria Barbosa‐Filho · Revista Brasileira de Farmacognosia | Mar 2007 | 664 |
| 4 | Caspases: pharmacological manipulation of cell death Inna N. Lavrik · Journal of Clinical Investigation | Oct 2005 | 648 |
| 5 | Prokaryotic Hopanoids and other Polyterpenoid Sterol Surrogates Guy Ourisson, Michel Rohmer, Karl Poralla · Annual Review of Microbiology | Oct 1987 | 579 |
| 6 | Biflavonoids from Torreya nucifera displaying SARS-CoV 3CLpro inhibition Young Bae Ryu, Hyung Jae Jeong, Jang Hoon Kim et al. · Bioorganic & Medicinal Chemistry | 20 Sep 2010 | 558 |
| 7 | Diterpenoids from Isodon species and their biological activities Han‐Dong Sun, Sheng‐Xiong Huang, Quan‐Bin Han · Natural Product Reports | 2006 | 551 |
| 8 | Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012) Andrea Vasas, Judit Hohmann · Chemical Reviews | 18 Jul 2014 | 506 |
| 9 | Chemical and Pharmacological Research of the Plants in Genus Euphorbia Qing‐Wen Shi, Xiao-Hui Su, Hiromasa Kiyota · Chemical Reviews | 25 Sep 2008 | 500 |
| 10 | Traditional uses, chemistry and pharmacology of Croton species (Euphorbiaceae) Antônio Salatino, Maria Luiza Faria Salatino, Giuseppina Negri · Journal of the Brazilian Chemical Society | 2007 | 487 |
| 11 | Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage José Marı́a Gutiérrez, Alexandra Rucavado, Teresa Escalante et al. · Toxicon | 19 Apr 2005 | 471 |
| 12 | Aconitum in Traditional Chinese Medicine—A valuable drug or an unpredictable risk? Judith Singhuber, Ming Zhu, Sonja Prinz et al. · Journal of Ethnopharmacology | 4 Aug 2009 | 468 |
| 13 | Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells Jiali Yang, Cuicui Pi, Guanghui Wang · Biomedicine & Pharmacotherapy | 24 Apr 2018 | 457 |
| 14 | Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper ARPAD SZALLASI, Peter M. Blumberg · Neuroscience | 1989 | 440 |
| 15 | Bioactivity-Based Molecular Networking for the Discovery of Drug Leads in Natural Product Bioassay-Guided Fractionation Louis-Félix Nothias-Scaglia, Mélissa Nothias-Esposito, Ricardo Silva et al. · Journal of Natural Products | 2 Mar 2018 | 434 |
| 16 | Protein kinase C as the receptor for the phorbol ester tumor promoters: sixth Rhoads memorial award lecture. Peter M. Blumberg · PubMed | 1988 | 430 |
| 17 | harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival‐promoting proteins Bcl‐2 and Bcl‐XL Naohiro Inohara, Liyun Ding, Shu Chen et al. · The EMBO Journal | Apr 1997 | 395 |
| 18 | Withaferin A is a potent inhibitor of angiogenesis Royce Mohan, Hans J. Hammers, Paola Bargagna‐Mohan et al. · Angiogenesis | 2004 | 383 |
| 19 | The Triterpenoid Betulin Protects against the Neuromuscular Effects ofBothrops jararacussuSnake VenomIn Vivo Miriéle Cristina Ferraz, Jhones Luiz de Oliveira, Joel Reis de Oliveira et al. · Evidence-based Complementary and Alternative Medicine | 2015 | 373 |
| 20 | Specific binding of phorbol ester tumor promoters Paul E. Driedger, Peter M. Blumberg · Proceedings of the National Academy of Sciences | 1980 | 361 |
| 21 | Euphorbia hirta: Its chemistry, traditional and medicinal uses, and pharmacological activities Sunil Kumar, Rashmi Malhotra, Dinesh Kumar · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review | 2010 | 355 |
| 22 | 14-Step Synthesis of (+)-Ingenol from (+)-3-Carene Lars Jørgensen, Steven J. McKerrall, Christian A. Kuttruff et al. · Science | 2 Aug 2013 | 349 |
| 23 | Pinocembrin: A Novel Natural Compound with Versatile Pharmacological and Biological Activities Azhar Rasul, Faya Martin Millimouno, Wafa Ali Eltayb et al. · BioMed Research International | 2013 | 348 |
| 24 | Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion Jing‐Yan Han, Jing‐Yu Fan, Yoshinori Horie et al. · Pharmacology & Therapeutics | 4 Dec 2007 | 343 |
| 25 | CARD11 and CARD14 Are Novel Caspase Recruitment Domain (CARD)/Membrane-associated Guanylate Kinase (MAGUK) Family Members that Interact with BCL10 and Activate NF-κB John Bertin, Lin Wang, Yin Guo et al. · Journal of Biological Chemistry | Apr 2001 | 342 |
| 26 | Cell death in intervertebral disc degeneration Fan Ding, Zengwu Shao, Liming Xiong · APOPTOSIS | 19 Mar 2013 | 337 |
| 27 | β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation Kyung‐Ran Park, Dongwoo Nam, Hyung‐Mun Yun et al. · Cancer Letters | 30 Aug 2011 | 336 |
| 28 | Diterpenoid alkaloids Feng‐Peng Wang, Qiao‐Hong Chen, Xiaoyu Liu · Natural Product Reports | 2010 | 329 |
| 29 | Syzygium cumini extract induced reactive oxygen species‐mediated apoptosis in human oral squamous carcinoma cells Devaraj Ezhilarasan, Velluru S. Apoorva, Nandhigam Ashok Vardhan · Journal of Oral Pathology and Medicine | 19 Nov 2018 | 326 |
| 30 | The antibacterial properties of Malaysian tualang honey against wound and enteric microorganisms in comparison to manuka honey Hern‐Tze Tina Tan, Rosliza Abdul Rahman, Siew Hua Gan et al. · BMC Complementary and Alternative Medicine | 15 Sep 2009 | 326 |
| 31 | Topical Use of Dexpanthenol in Skin Disorders Fritz Ebner, Andreas Heller, Frank Rippke et al. · American Journal of Clinical Dermatology | 2002 | 312 |
| 32 | Antibacterial activity of the essential oils from the leaves of Eucalyptus globulus against Escherichia coli and Staphylococcus aureus Raho Ghalem Bachir, M Benali · Asian Pacific Journal of Tropical Biomedicine | 10 Jun 2012 | 311 |
| 33 | Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways Huahong Yang, Hongming Lv, Haijun Li et al. · Cell Communication and Signaling | 11 Jun 2019 | 291 |
| 34 | Antimicrobial activities of eucalyptus leaf extracts and flavonoids from Eucalyptus maculata Tomio Takahashi, Ryoma Kokubo, M. Sakaino · Letters in Applied Microbiology | 9 Jun 2004 | 283 |
| 35 | Cytochrome P450 enzymes: A driving force of plant diterpene diversity Ulschan Bathe, Alain F. Tissier · Phytochemistry | 5 Feb 2019 | 281 |
| 36 | MK-1775, a Potent Wee1 Inhibitor, Synergizes with Gemcitabine to Achieve Tumor Regressions, Selectively in p53-Deficient Pancreatic Cancer Xenografts N.V. Rajeshkumar, Elizabeth De Oliveira, Niki A. Ottenhof et al. · Clinical Cancer Research | 10 Mar 2011 | 281 |
| 37 | Eugenol isolated from the essential oil of Eugenia caryophyllata induces a reactive oxygen species-mediated apoptosis in HL-60 human promyelocytic leukemia cells Chae-Bin Yoo, Ki-Tae Han, Kyu-Seok Cho et al. · Cancer Letters | 16 Dec 2004 | 263 |
| 38 | Caspase-8: The double-edged sword Ranadip Mandal, Joan Compte, Izabela Kostova et al. · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer | 9 Mar 2020 | 258 |
| 39 | Diterpenoids from Isodon species: an update Miao Liu, Wei‐Guang Wang, Han‐Dong Sun et al. · Natural Product Reports | 2017 | 256 |
| 40 | Antitumor Activity of 3-Ingenyl Angelate Steven M. Ogbourne, Andreas Suhrbier, Brad Jones et al. · Cancer Research | 15 Apr 2004 | 256 |
| 41 | Chemical composition and antibacterial activities of seven Eucalyptus species essential oils leaves Khaled Sebei, Fawzi Sakouhi, Wahid Herchi et al. · Biological Research | 2015 | 255 |
| 42 | The chemistry of taxol David G. I. Kingston · Pharmacology & Therapeutics | Oct 1991 | 254 |
| 43 | Incidence and mortality due to snakebite in the Americas Jean‐Philippe Chippaux · PLoS neglected tropical diseases | 21 Jun 2017 | 253 |
| 44 | The genus Rhododendron: An ethnopharmacological and toxicological review Ruxandra Popescu, Brigitte Kopp · Journal of Ethnopharmacology | 27 Feb 2013 | 253 |
| 45 | Nineteen-step total synthesis of (+)-phorbol Shuhei Kawamura, Hang Chu, Jakob Felding et al. · Nature | 22 Mar 2016 | 251 |
| 46 | The First α Helix of Bax Plays a Necessary Role in Its Ligand-Induced Activation by the BH3-Only Proteins Bid and PUMA Pierre‐François Cartron, Tristan Gallenne, Gwenola Bougras et al. · Molecular Cell | Dec 2004 | 250 |
| 47 | Antitumor Activity and Antioxidant Status of Caesalpinia bonducella Against Ehrlich Ascites Carcinoma in Swiss Albino Mice Malaya Gupta, Upal Kanti Mazumder, Ramanathan Sambath Kumar et al. · Journal of Pharmacological Sciences | 2004 | 242 |
| 48 | Chemical composition of 8 eucalyptus species' essential oils and the evaluation of their antibacterial, antifungal and antiviral activities Ameur Elaissi, Zyed Rouis, Nabil Ben Salem Abid et al. · BMC Complementary and Alternative Medicine | 28 Jun 2012 | 242 |
| 49 | Isolation of rhododaurichromanic acid B and the anti-HIV principles rhododaurichromanic acid A and rhododaurichromenic acid from Rhododendron dauricum Yoshiki Kashiwada, Kimihisa Yamazaki, Yasumasa Ikeshiro et al. · Tetrahedron | Feb 2001 | 238 |
| 50 | A new muscle damaging toxin, myotoxin II, from the venom of the snake Bothrops asper (terciopelo) Bruno Lomonte, José Marı́a Gutiérrez · Toxicon | 1989 | 231 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.