Science Explorer Back to mapMap

Most cited papers in Biological Research and Disease Studies

Biological Research and Disease Studies

What are the most cited papers in Biological Research and Disease Studies?

The most cited paper in Biological Research and Disease Studies is "The global prevalence of dementia: A systematic review and metaanalysis" (Martin James Prince, Renata Bryce, Emiliano Albanese et al., 2013), with 4,986 citations. Next come "Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement" (4,836) and "NanoPack: visualizing and processing long-read sequencing data" (3,475).

Showing 50 of 100 papers. Every paper with more than 582 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The global prevalence of dementia: A systematic review and metaanalysis Martin James Prince, Renata Bryce, Emiliano Albanese et al. · Alzheimer s & Dementia ReviewOpen access 2013 4,986
2 Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement David Moher, Deborah J Cook, Susan Eastwood et al. · The Lancet Nov 1999 4,836
3 NanoPack: visualizing and processing long-read sequencing data Wouter De Coster, Svenn D’Hert, Darrin T. Schultz et al. · Bioinformatics Open access 12 Mar 2018 3,475
4 Donanemab in Early Symptomatic Alzheimer Disease John Randall Sims et al. · JAMA Open access309 authors 17 Jul 2023 2,880
5 Alzheimer disease in the United States (2010–2050) estimated using the 2010 census Liesi E. Hebert, Jennifer Weuve, Paul A. Scherr et al. · Neurology Open access 7 Feb 2013 2,721
6 An Overview of Autophagy: Morphology, Mechanism, and Regulation Katherine R. Parzych, Daniel J. Klionsky · Antioxidants and Redox Signaling Open access 3 Jun 2013 2,585
7 Reported Methodologic Quality and Discrepancies between Large and Small Randomized Trials in Meta-Analyses Lise Lotte Kjaergard, John Villumsen, Christian Nyfeldt Gluud · Annals of Internal Medicine 4 Dec 2001 2,341
8 Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo Amelia M. Bartholomew, Cord Sturgeon, Mandy Siatskas et al. · Experimental Hematology Open access 2002 2,297
9 Alzheimer Disease in the US Population Liesi E. Hebert, Paul A. Scherr, Julia L. Bienias et al. · Archives of Neurology Aug 2003 2,183
10 Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Toshiyuki Miyashita, Stanisław Krajewski, Maryla Krajewska et al. · PubMed Jun 1994 2,164
11 Tumor spectrum analysis in p53-mutant mice Tyler Jacks, Lee Ann Remington, Bart O. Williams et al. · Current Biology 1994 2,095
12 In Silico Approach for Predicting Toxicity of Peptides and Proteins Sudheer Gupta, Pallavi Kapoor, Kumardeep Chaudhary et al. · PLoS ONE Open access 13 Sep 2013 2,078
13 Introduction to the recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Clifford R. Jack, Marilyn Albert, David S. Knopman et al. · Alzheimer s & Dementia Open access 22 Apr 2011 2,073
14 Detection of Various Microplastics in Human Stool Philipp Schwabl, Sebastian Köppel, Philipp Königshofer et al. · Annals of Internal Medicine 2 Sep 2019 1,956
15 The global burden of typhoid fever. John A. Crump, Stephen P. Luby, Eric D. Mintz · PubMed Open access May 2004 1,955
16 Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis Jørn Wetterslev, Kristian Thorlund, Jesper Sune Brok et al. · Journal of Clinical Epidemiology 24 Aug 2007 1,929
17 Depression and poor glycemic control: a meta-analytic review of the literature. Patrick J. Lustman, Ryan J. Anderson, Kenneth E. Freedland et al. · Diabetes Care Jul 2000 1,861
18 Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial Barton F. Haynes et al. · New England Journal of Medicine Open access 4 Apr 2012 1,851
19 Alzheimer’s disease drug-development pipeline: few candidates, frequent failures Jeffrey L. Cummings, Travis Morstorf, Kate Zhong · Alzheimer s Research & Therapy Open access 3 Jul 2014 1,787
20 Antiretroviral Therapy for the Prevention of HIV-1 Transmission Myron S. Cohen et al. · New England Journal of Medicine Open access 18 Jul 2016 1,760
21 Hepatocellular Carcinoma Incidence, Mortality, and Survival Trends in the United States From 1975 to 2005 Sean F. Altekruse, Katherine A. McGlynn, Marsha E. Reichman · Journal of Clinical Oncology Open access 17 Feb 2009 1,702
22 Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease Rachelle Smith Doody, Ronald G. Thomas, Martin Rhys Farlow et al. · New England Journal of Medicine Open access 22 Jan 2014 1,675
23 Infection with chikungunya virus in Italy: an outbreak in a temperate region Giovanni Rezza, Loredana Nicoletti, Paola Angelini et al. · The Lancet Dec 2007 1,536
24 Diagnosis and Management of Dementia: Review Zoe Arvanitakis, Raj C. Shah, David Alan Bennett · JAMA Open access 22 Oct 2019 1,452
25 Dose escalation of a curcuminoid formulation Christopher D. Lao, Mack T. Ruffin, Daniel Paul Normolle et al. · BMC Complementary and Alternative Medicine Open access 17 Mar 2006 1,398
26 Acute Bacterial Meningitis in Adults -- A Review of 493 Episodes Marlene L. Durand, Stephen B. Calderwood, David Jay Weber et al. · New England Journal of Medicine 7 Jan 1993 1,369
27 Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: Updated criteria and genotype assignment web resource Donald B. Smith, Jens Bukh, Carla Kuiken et al. · Hepatology Open access 11 Oct 2013 1,365
28 Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood Wolfgang Wagner, Frederik Wein, Anja Seckinger et al. · Experimental Hematology Open access Nov 2005 1,266
29 Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors Manel Esteller · JNCI Journal of the National Cancer Institute 5 Apr 2000 1,238
30 Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women Breast Cancer Association Consortium · New England Journal of Medicine Open access 20 Jan 2021 1,192
31 Discrepancies between Meta-Analyses and Subsequent Large Randomized, Controlled Trials Jacques LeLorier, Geneviève Grégoire, A Aïssa Benhaddad et al. · New England Journal of Medicine Open access 21 Aug 1997 1,188
32 Type 2 Diabetes and its Impact on the Immune System Afiat Berbudi, Nofri Rahmadika, Adi Imam Tjahjadi et al. · Current Diabetes Reviews Open access 28 Oct 2019 1,167
33 Interventions to Enhance Patient Adherence to Medication Prescriptions Heather McDonald, Amit X. Garg, Robert Brian Haynes · JAMA 11 Dec 2002 1,141
34 Reversal of Lesions of Diabetic Nephropathy after Pancreas Transplantation Paola Fioretto, Michael W. Steffes, David E.R. Sutherland et al. · New England Journal of Medicine 9 Jul 1998 1,141
35 World Journal of Microbiology and Biotechnology 2008 Lynn G. Dover, Peter J. Large, Nasib Qureshi et al. · World Journal of Microbiology and Biotechnology 14 Jul 2008 1,132
36 Sorafenib for Treatment of Renal Cell Carcinoma: Final Efficacy and Safety Results of the Phase III Treatment Approaches in Renal Cancer Global Evaluation Trial Bernard J. Escudier, Tim G Eisen, Walter Michael Stadler et al. · Journal of Clinical Oncology Open access 18 May 2009 1,089
37 Prevalence and Severity of Food Allergies Among US Adults Ruchi S. Gupta, Christopher Michael Warren, Bridget Smith et al. · JAMA Network Open Open access 4 Jan 2019 1,036
38 Phase II Placebo-Controlled Randomized Discontinuation Trial of Sorafenib in Patients With Metastatic Renal Cell Carcinoma Mark J. Ratain, Tim G Eisen, Walter Michael Stadler et al. · Journal of Clinical Oncology Open access 24 Apr 2006 1,036
39 The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis Nader Salari, Hooman Ghasemi, Loghman Mohammadi et al. · Journal of Orthopaedic Surgery and Research ReviewOpen access 17 Oct 2021 1,032
40 Multiple Sclerosis: Current Knowledge and Future Outlook Christian P. Kamm, Bernard M.J. Uitdehaag, Chris H. Polman · European Neurology 2014 1,017
41 Efavirenz plus Zidovudine and Lamivudine, Efavirenz plus Indinavir, and Indinavir plus Zidovudine and Lamivudine in the Treatment of HIV-1 Infection in Adults Schlomo Staszewski, Javier O Morales-Ramirez, Karen T. Tashima et al. · New England Journal of Medicine Open access 16 Dec 1999 1,010
42 Azithromycin in Patients With Cystic Fibrosis Chronically Infected With Pseudomonas aeruginosa Lisa M. Saiman, Bruce C. Marshall, Nicole Mayer-Hamblett et al. · JAMA 30 Sep 2003 961
43 Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America Luis Angel Villar et al. · New England Journal of Medicine Open access 3 Nov 2014 958
44 Folic Acid for the Prevention of Colorectal Adenomas Bernard F. Cole et al. · JAMA 5 Jun 2007 935
45 Diagnosis and Treatment of Alzheimer Disease and Related Disorders Gary W. Small · JAMA 22 Oct 1997 934
46 Outcomes and Prognostic Factors in Recurrent Glioma Patients Enrolled Onto Phase II Clinical Trials Eric T. Wong, Kenneth R. Hess, Mary Jo Gleason et al. · Journal of Clinical Oncology Aug 1999 907
47 Lifetime Cancer Risks in Individuals with GermlinePTENMutations Min-Han Tan, Jessica L. Mester, Joanne Yuen Yie Ngeow et al. · Clinical Cancer Research Open access 15 Jan 2012 900
48 Purification of human erythropoietin. Takahito Miyake, Charles K.-H. Kung, Eugene Goldwasser · Journal of Biological Chemistry Open access Aug 1977 896
49 A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. Jon M. Huibregtse, Martin Scheffner, Peter M. Howley · The EMBO Journal Open access Dec 1991 893
50 Phase III Randomized Trial of Cisplatin Plus Placebo Compared With Cisplatin Plus Cetuximab in Metastatic/Recurrent Head and Neck Cancer: An Eastern Cooperative Oncology Group Study Barbara Ann Burtness, Meredith A. Goldwasser, William A. Flood et al. · Journal of Clinical Oncology 28 Nov 2005 885

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.