Topic · Biomedical Ethics and Regulation
Most cited papers in Biomedical Ethics and Regulation
What are the most cited papers in Biomedical Ethics and Regulation?
The most cited paper in Biomedical Ethics and Regulation is "ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells" (Daniel W. Lee et al., 2018), with 3,663 citations. Next come "Bone marrow transplant" (3,412) and "Raise standards for preclinical cancer research" (2,968).
Showing 50 of 100 papers. Every paper with more than 487 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells Daniel W. Lee et al. · Transplantation and Cellular Therapy | 25 Dec 2018 | 3,663 |
| 2 | Bone marrow transplant Angela Joyce · Nursing Children and Young People | Sep 1989 | 3,412 |
| 3 | Raise standards for preclinical cancer research C. Glenn Begley, Lee M. Ellis · Nature | 27 Mar 2012 | 2,968 |
| 4 | The Belmont Report: ethical principles and guidelines for the protection of human subjects of research Sue Eckstein · Cambridge University Press eBooks | 20 Feb 2003 | 2,712 |
| 5 | What Makes Clinical Research Ethical? Ezekiel J. Emanuel · JAMA | 24 May 2000 | 2,701 |
| 6 | Ethical principles for medical research involving human subjects Sue Eckstein · Cambridge University Press eBooks | 20 Feb 2003 | 2,605 |
| 7 | THE JOURNAL OF REPRODUCTIVE MEDICINE Diane M. Reddy, Sheldon A. Wasserman · AJN American Journal of Nursing | 1999 | 2,517 |
| 8 | Chimeric Antigen Receptor Therapy Carl H. June, Michel Sadelain · New England Journal of Medicine | 4 Jul 2018 | 2,379 |
| 9 | Equipoise and the Ethics of Clinical Research Benjamin Freedman · New England Journal of Medicine | 16 Jul 1987 | 2,359 |
| 10 | A more efficient method to generate integration-free human iPS cells Keisuke Okita, Yasuko Matsumura, Yoshiko Sato et al. · Nature Methods | 3 Apr 2011 | 2,121 |
| 11 | Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement E.M. Horwitz, Katarina Le Blanc, Massimo Dominici et al. · Cytotherapy | 2005 | 2,079 |
| 12 | Derivation of pluripotent epiblast stem cells from mammalian embryos I. G. M. Brons, Lucy E. Smithers, Matthew W. B. Trotter et al. · Nature | 27 Jun 2007 | 2,046 |
| 13 | Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons John T. Dimos, Kit T. Rodolfa, Kathy K. Niakan et al. · Science | 31 Jul 2008 | 1,999 |
| 14 | Ethics and Clinical Research Henry K. Beecher · New England Journal of Medicine | 16 Jun 1966 | 1,919 |
| 15 | Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors Frank Soldner, Dirk F. Hockemeyer, Caroline Beard et al. · Cell | Mar 2009 | 1,557 |
| 16 | Stem Cell Therapies in Clinical Trials: Progress and Challenges Alan Trounson, Courtney A. McDonald · Cell stem cell | Jul 2015 | 1,504 |
| 17 | Changing potency by spontaneous fusion Qi‐Long Ying, Jennifer Nichols, E.P. Evans et al. · Nature | 13 Mar 2002 | 1,499 |
| 18 | Immunogenicity of induced pluripotent stem cells Tongbiao Zhao, Zhen‐Ning Zhang, Zhili Rong et al. · Nature | 13 May 2011 | 1,451 |
| 19 | Emerging trends in regenerative medicine: a scientometric analysis inCiteSpace Chaomei Chen, Zhigang Hu, Shengbo Liu et al. · Expert Opinion on Biological Therapy | 25 Mar 2012 | 1,370 |
| 20 | Pluripotent Stem Cell-Based Cell Therapy—Promise and Challenges Shinya Yamanaka · Cell stem cell | Oct 2020 | 1,251 |
| 21 | The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine Paolo Bianco, Xu Cao, Paul S. Frenette et al. · Nature Medicine | 2013 | 1,226 |
| 22 | The Theory and Practice of Industrial Pharmacy Gilbert S. Banker · Journal of Pharmaceutical Sciences | Oct 1970 | 1,186 |
| 23 | Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials Manoj Mathew Lalu, Lauralyn McIntyre, Christina Pugliese et al. · PLoS ONE | 25 Oct 2012 | 1,164 |
| 24 | Mesenchymal Stem Cells: Time to Change the Name! Arnold I. Caplan · Stem Cells Translational Medicine | 28 Apr 2017 | 1,157 |
| 25 | Reconstruction of Tissues by Dissociated Cells Malcolm S. Steinberg · Science | 2 Aug 1963 | 1,141 |
| 26 | Adipose-derived adult stem cells: isolation, characterization, and differentiation potential Jeffrey M. Gimble, Farshid Guilak · Cytotherapy | 2003 | 1,109 |
| 27 | The Evolving Concept of a Stem Cell Helen M. Blau, Tim R. Brazelton, James M. Weimann · Cell | Jun 2001 | 1,054 |
| 28 | THE JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Jason G. Smith · International Journal of Dermatology | Jul 1979 | 1,050 |
| 29 | p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells Robert J. Ihry, Kathleen A. Worringer, Max R. Salick et al. · Nature Medicine | 8 Jun 2018 | 1,041 |
| 30 | The Declaration of Helsinki and public health John James Williams · Bulletin of the World Health Organization | Aug 2008 | 992 |
| 31 | Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells Miguel Angel Esteban et al. · Cell stem cell | 2010 | 980 |
| 32 | Derivation of Embryonic Stem-Cell Lines from Human Blastocysts Chad A. Cowan, Irina V. Klimanskaya, Jill A. McMahon et al. · New England Journal of Medicine | 24 Mar 2004 | 976 |
| 33 | What Makes Clinical Research in Developing Countries Ethical? The Benchmarks of Ethical Research Ezekiel J. Emanuel, David S. Wendler, Jack Killen et al. · The Journal of Infectious Diseases | 23 Feb 2004 | 970 |
| 34 | False Hopes and Best Data: Consent to Research and the Therapeutic Misconception Paul S. Appelbaum, Loren H. Roth, Charles W. Lidz et al. · The Hastings Center Report | Apr 1987 | 967 |
| 35 | Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia Bianca Santomasso et al. · Cancer Discovery | 7 Jun 2018 | 949 |
| 36 | Ethical and Safety Issues of Stem Cell-Based Therapy Vladislav Volarević, Bojana Simović Marković, Marina Gazdic et al. · International Journal of Medical Sciences | 11 Dec 2017 | 912 |
| 37 | Placebo-Controlled Trials and Active-Control Trials in the Evaluation of New Treatments. Part 1: Ethical and Scientific Issues Robert Temple, Susan S. Ellenberg · Annals of Internal Medicine | 19 Sep 2000 | 889 |
| 38 | Variation in the safety of induced pluripotent stem cell lines Kyoko Miura, Yohei Okada, Takashi Aoi et al. · Nature Biotechnology | 9 Jul 2009 | 888 |
| 39 | Are Racial and Ethnic Minorities Less Willing to Participate in Health Research? David S. Wendler, Raynard S. Kington, Jennifer H. Madans et al. · PLoS Medicine | 30 Nov 2005 | 872 |
| 40 | OMERACT-OARSI Initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisited. T Pham, D. van der Heijde, Roy Davis Altman et al. · Osteoarthritis and Cartilage | 20 Mar 2004 | 869 |
| 41 | Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature Sowmya Viswanathan, Yufang Shi, Jacques Galipeau et al. · Cytotherapy | 13 Sep 2019 | 866 |
| 42 | Adv. Drug Delivery Rev. Frederick G.P. Welt, Elazer Reuven Edelman · Advanced Drug Delivery Reviews | May 1997 | 864 |
| 43 | Translating Stem and Progenitor Cell Biology to the Clinic: Barriers and Opportunities Irving L. Weissman · Science | 25 Feb 2000 | 857 |
| 44 | Emerging trends and new developments in regenerative medicine: a scientometric update (2000 – 2014) Chaomei Chen, Rachael Dubin, Meen Chul Kim · Expert Opinion on Biological Therapy | 31 Jul 2014 | 849 |
| 45 | Induced Pluripotent Stem Cells: Past, Present, and Future Shinya Yamanaka · Cell stem cell | Jun 2012 | 845 |
| 46 | A Brief Definition of Regenerative Medicine Chris Mason, Peter Dunnill · Regenerative Medicine | 21 Dec 2007 | 799 |
| 47 | iPS cells produce viable mice through tetraploid complementation Xiaoyang Zhao, Wei Li, Zhuo Lv et al. · Nature | 23 Jul 2009 | 787 |
| 48 | Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells Yoshinori Yoshida, Kazutoshi Takahashi, Keisuke Okita et al. · Cell stem cell | 28 Aug 2009 | 774 |
| 49 | Risk factors in the development of stem cell therapy Carla A. Herberts, Marcel Kwa, Harm PH Hermsen · Journal of Translational Medicine | 22 Mar 2011 | 773 |
| 50 | Executive summary: stages of reproductive aging workshop (STRAW) Michael R. Soules, Sherry Sherman, Estella C. Parrott et al. · Fertility and Sterility | Nov 2001 | 763 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.