Most cited papers in Biosensors and Analytical Detection
What are the most cited papers in Biosensors and Analytical Detection?
The most cited paper in Biosensors and Analytical Detection is "A new generation of Ca2+ indicators with greatly improved fluorescence properties." (Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien, 1985), with 21,798 citations. Next come "High resolution two-dimensional electrophoresis of proteins." (19,391) and "Loop-mediated isothermal amplification of DNA" (8,938).
Showing 50 of 100 papers. Every paper with more than 1,167 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry | Mar 1985 | 21,798 |
| 2 | High resolution two-dimensional electrophoresis of proteins. Patrick H. O’Farrell · Journal of Biological Chemistry | May 1975 | 19,391 |
| 3 | Loop-mediated isothermal amplification of DNA Tsugunori Notomi · Nucleic Acids Research | 15 Jun 2000 | 8,938 |
| 4 | Intrinsic peroxidase-like activity of ferromagnetic nanoparticles Lizeng Gao, Jie Zhuang, Leng Nie et al. · Nature Nanotechnology | 26 Aug 2007 | 7,484 |
| 5 | Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS) Katrin D. Kneipp, Yang Wang, Harald Kneipp et al. · Physical Review Letters | 3 Mar 1997 | 6,807 |
| 6 | Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods Xiaohua Huang, Ivan H. El‐Sayed, Wei Ping Qian et al. · Journal of the American Chemical Society | 21 Jan 2006 | 5,431 |
| 7 | Rapid colorimetric assay for cell growth and survival François Denizot, Rita Lang · Journal of Immunological Methods | May 1986 | 4,918 |
| 8 | Nanostructures in Biodiagnostics Nathaniel L. Rosi, Chad Alexander Mirkin · Chemical Reviews | 23 Mar 2005 | 4,579 |
| 9 | Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles Robert Elghanian, James Justin Storhoff, Robert C. Mucic et al. · Science | 22 Aug 1997 | 4,399 |
| 10 | Comprehensive Evaluation of Antibiotics Emission and Fate in the River Basins of China: Source Analysis, Multimedia Modeling, and Linkage to Bacterial Resistance Qian-Qian Zhang, Guang‐Guo Ying, Chang‐Gui Pan et al. · Environmental Science & Technology | 11 May 2015 | 3,925 |
| 11 | Real-Time DNA Sequencing from Single Polymerase Molecules John S. Eid et al. · Science | 20 Nov 2008 | 3,878 |
| 12 | Wearable biosensors for healthcare monitoring Jayoung Kim, Alan S. Campbell, Berta Esteban‐Fernández de Ávila et al. · Nature Biotechnology | 25 Feb 2019 | 3,349 |
| 13 | Surface-Enhanced Raman Spectroscopy Paul L. Stiles, Jon A. Dieringer, Nilam C. Shah et al. · Annual Review of Analytical Chemistry | 7 May 2008 | 3,173 |
| 14 | Nanoparticles with Raman Spectroscopic Fingerprints for DNA and RNA Detection YunWei Charles Cao, Rongchao Jin, Chad Alexander Mirkin · Science | 29 Aug 2002 | 2,977 |
| 15 | Patterned Paper as a Platform for Inexpensive, Low‐Volume, Portable Bioassays Andres W. Martinez, Scott T. Phillips, Manish J. Butte et al. · Angewandte Chemie International Edition | 9 Jan 2007 | 2,879 |
| 16 | Diagnostics for the Developing World: Microfluidic Paper-Based Analytical Devices Andres W. Martinez, Scott T. Phillips, George M. Whitesides et al. · Analytical Chemistry | 9 Dec 2009 | 2,678 |
| 17 | DNA Detection Using Recombination Proteins Olaf Piepenburg, Colin Haslehurst Williams, Derek L. Stemple et al. · PLoS Biology | 6 Jun 2006 | 2,559 |
| 18 | SERS: Materials, applications, and the future Bhavya Sharma, Renee R. Frontiera, Anne-Isabelle Henry et al. · Materials Today | 2012 | 2,479 |
| 19 | Multiplexed electrical detection of cancer markers with nanowire sensor arrays Gengfeng Zheng, Fernando Patolsky, Yi Xiao Cui et al. · Nature Biotechnology | 18 Sep 2005 | 2,437 |
| 20 | Scanometric DNA Array Detection with Nanoparticle Probes T. Andrew Taton, Chad Alexander Mirkin, Robert L. Letsinger · Science | 8 Sep 2000 | 2,411 |
| 21 | Nanoparticle-Based Bio-Bar Codes for the Ultrasensitive Detection of Proteins Jin‐Min Nam, Colby Shad Thaxton, Chad Alexander Mirkin · Science | 25 Sep 2003 | 2,395 |
| 22 | One-Pot Colorimetric Differentiation of Polynucleotides with Single Base Imperfections Using Gold Nanoparticle Probes James Justin Storhoff, Robert Elghanian, Robert C. Mucic et al. · Journal of the American Chemical Society | 20 Feb 1998 | 2,276 |
| 23 | Aptamers as targeted therapeutics: current potential and challenges Jiehua Zhou, John J. Rossi · Nature Reviews Drug Discovery | 3 Nov 2016 | 2,246 |
| 24 | Functional Nucleic Acid Sensors Juewen Liu, Zehui Charles Cao, Yi Lu · Chemical Reviews | 20 Mar 2009 | 2,178 |
| 25 | A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots M. S. Blake, Kenneth H. Johnston, G.J. Russell-Jones et al. · Analytical Biochemistry | 1984 | 2,152 |
| 26 | Electrowetting: from basics to applications Frieder G. Mugele, Jean‐Christophe Baret · Journal of Physics Condensed Matter | Jul 2005 | 2,097 |
| 27 | Accelerated reaction by loop-mediated isothermal amplification using loop primers Kentaro Nagamine, T. HASE, Tsugunori Notomi · Molecular and Cellular Probes | Jun 2002 | 2,081 |
| 28 | A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors Varnakavi Naresh, Nohyun Lee · Sensors | 5 Feb 2021 | 2,053 |
| 29 | Applications of nanotechnology in food packaging and food safety: Barrier materials, antimicrobials and sensors Timothy V. Duncan · Journal of Colloid and Interface Science | 25 Jul 2011 | 2,030 |
| 30 | Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability Erika Assarsson, Martin Lundberg, Göran Holmquist et al. · PLoS ONE | 22 Apr 2014 | 1,983 |
| 31 | First confirmed detection of SARS-CoV-2 in untreated wastewater in Australia: A proof of concept for the wastewater surveillance of COVID-19 in the community Warish Ahmed, Nicola Z. Angel, Janette Edson et al. · The Science of The Total Environment | 17 Apr 2020 | 1,980 |
| 32 | Microfluidic diagnostic technologies for global public health Paul Yager, Thayne L. Edwards, Elain S. Fu et al. · Nature | 26 Jul 2006 | 1,971 |
| 33 | Gold nanoparticles in biomedical applications: recent advances and perspectives Lev A. Dykman, Nikolai G. Khlebtsov · Chemical Society Reviews | Dec 2011 | 1,960 |
| 34 | Paper-based microfluidic point-of-care diagnostic devices Ali K. Yetisen, Muhammad Safwan Akram, Christopher Robin Lowe · Lab on a Chip | 2013 | 1,945 |
| 35 | Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges Cheng Zong, Mengxi Xu, Lijia Xu et al. · Chemical Reviews | 11 Apr 2018 | 1,941 |
| 36 | Loop-mediated isothermal amplification (LAMP) of gene sequences and simple visual detection of products Norihiro Tomita, Yasuyoshi Mori, Hidetoshi Kanda et al. · Nature Protocols | 24 Apr 2008 | 1,893 |
| 37 | Antibacterial Activity and Mechanism of Action of the Silver Ion in Staphylococcus aureus and Escherichia coli Woo Kyung Jung, Hye Cheong Koo, Ki Woo Kim et al. · Applied and Environmental Microbiology | Feb 2008 | 1,857 |
| 38 | Isothermal Amplification of Nucleic Acids Yongxi Zhao, Feng Chen, Qian Li et al. · Chemical Reviews | 9 Nov 2015 | 1,803 |
| 39 | Biological applications of gold nanoparticles Ralph A. Sperling, Pilar Rivera-Gil, Feng Zhang et al. · Chemical Society Reviews | 2008 | 1,803 |
| 40 | Selection of housekeeping genes for gene expression studies in human reticulocytes using real-time PCR Nicholas Silver, Steve Best, Jie Jiang et al. · BMC Molecular Biology | 6 Oct 2006 | 1,774 |
| 41 | Detection of Loop-Mediated Isothermal Amplification Reaction by Turbidity Derived from Magnesium Pyrophosphate Formation Yasuyoshi Mori, Kentaro Nagamine, Norihiro Tomita et al. · Biochemical and Biophysical Research Communications | Nov 2001 | 1,733 |
| 42 | Plasmofluidic single-molecule surface-enhanced Raman scattering from dynamic assembly of plasmonic nanoparticles Partha Patra, Rohit Chikkaraddy, Ravi P. N. Tripathi et al. · Nature Communications | 7 Jul 2014 | 1,706 |
| 43 | Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo Florence Debacq‐Chainiaux, Jorge D. Erusalimsky, Judith Campisi et al. · Nature Protocols | 19 Nov 2009 | 1,706 |
| 44 | SHERLOCK: nucleic acid detection with CRISPR nucleases Max J. Kellner, Jeremy G. Koob, Jonathan S. Gootenberg et al. · Nature Protocols | 23 Sep 2019 | 1,701 |
| 45 | Improved technique utilizing nonfat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose David A. Johnson, James W. Gautsch, J. Richard Sportsman et al. · Gene Analysis Techniques | 1984 | 1,686 |
| 46 | Biosensors: sense and sensibility Anthony P.F. Turner · Chemical Society Reviews | 2013 | 1,654 |
| 47 | Pharmaceutical pollution of the world’s rivers John L. Wilkinson et al. · Proceedings of the National Academy of Sciences | 14 Feb 2022 | 1,634 |
| 48 | Understanding Wax Printing: A Simple Micropatterning Process for Paper-Based Microfluidics Emanuel Carrilho, Andres W. Martinez, George M. Whitesides · Analytical Chemistry | 15 Jul 2009 | 1,618 |
| 49 | Self-assembled nanoscale biosensors based on quantum dot FRET donors Igor L. Medintz, Aaron R. Clapp, Hedi M. Mattoussi et al. · Nature Materials | 24 Aug 2003 | 1,599 |
| 50 | Proteomic Analysis of the Mode of Antibacterial Action of Silver Nanoparticles Chun‐Nam Lok, Chi‐Ming Ho, Rong Chen et al. · Journal of Proteome Research | 16 Mar 2006 | 1,589 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.