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Most cited papers in Blood transfusion and management

What are the most cited papers in Blood transfusion and management?

The most cited paper in Blood transfusion and management is "A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care" (Paul C. Hébert, George A. Wells, Morris A. Blajchman et al., 1999), with 5,247 citations. Next come "Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma" (2,550) and "Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma" (2,425).

Showing 50 of 100 papers. Every paper with more than 598 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care Paul C. Hébert, George A. Wells, Morris A. Blajchman et al. · New England Journal of Medicine Open access 11 Feb 1999 5,247
2 Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma John B. Holcomb et al. · JAMA Open access 3 Feb 2015 2,550
3 Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma Chenguang Shen et al. · JAMA Open access 27 Mar 2020 2,425
4 The endothelial glycocalyx: composition, functions, and visualization Sietze Reitsma, Dick W. Slaaf, Hans Vink et al. · Pflügers Archiv - European Journal of Physiology Open access 25 Jan 2007 2,006
5 Anemia and Blood Transfusion in Critically Ill Patients Jean‐Louis Vincent · JAMA 25 Sep 2002 1,835
6 Nanoparticle biointerfacing by platelet membrane cloaking Che‐Ming Jack Hu et al. · Nature Open access 16 Sep 2015 1,814
7 Transfusion Strategies for Acute Upper Gastrointestinal Bleeding Càndid Villanueva, Alan Colomo, Alba Fernández Bosch et al. · New England Journal of Medicine Open access 2 Jan 2013 1,748
8 The Ratio of Blood Products Transfused Affects Mortality in Patients Receiving Massive Transfusions at a Combat Support Hospital Matthew A. Borgman, Philip Charles Spinella, Jeremy G. Perkins et al. · The Journal of Trauma: Injury, Infection, and Critical Care Oct 2007 1,590
9 Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial Haleema Shakur‐Still et al. · The Lancet Open access493 authors 26 Apr 2017 1,485
10 EFFECT OF HUMAN ERYTHROPOIETIN DERIVED FROM RECOMBINANT DNA ON THE ANAEMIA OF PATIENTS MAINTAINED BY CHRONIC HAEMODIALYSIS C. Winearls, MartinJ Pippard, M R Downing et al. · The Lancet Nov 1986 1,412
11 Increased Mortality, Postoperative Morbidity, and Cost After Red Blood Cell Transfusion in Patients Having Cardiac Surgery Gavin James Murphy, Barnaby C Reeves, Chris A. Rogers et al. · Circulation 12 Nov 2007 1,403
12 Duration of Red-Cell Storage and Complications after Cardiac Surgery Colleen Gorman Koch, Liang Li, Daniel I. Sessler et al. · New England Journal of Medicine Open access 19 Mar 2008 1,381
13 The CRIT Study: Anemia and blood transfusion in the critically ill—Current clinical practice in the United States* Howard L. Corwin, Andrew Gettinger, Ronald G. Pearl et al. · Critical Care Medicine 2004 1,357
14 Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery Jeffrey L. Carson, Michael L. Terrin, Helaine Noveck et al. · New England Journal of Medicine Open access 14 Dec 2011 1,328
15 2011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines Victor A. Ferraris, Jeremiah R. Brown, George John Despotis et al. · The Annals of Thoracic Surgery Open access 24 Feb 2011 1,322
16 The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial ‡ · The Lancet Mar 2011 1,276
17 Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study Khaled M. Musallam, Hani Tamim, Toby Richards et al. · The Lancet Oct 2011 1,274
18 Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial Michael Henke, Roland Laszig, Christian Rübe et al. · The Lancet Oct 2003 1,255
19 Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion Jeffrey L. Carson, Simon J. Stanworth, Nareg H. Roubinian et al. · Cochrane Database of Systematic Reviews Open access 12 Oct 2016 1,227
20 Clinical Outcomes after Transfusion-Associated Hepatitis C Myron John Tong, Neveen S. El-Farra, Andrew R. Reikes et al. · New England Journal of Medicine Open access Jun 1995 1,220
21 Recombinant Activated Factor VII for Acute Intracerebral Hemorrhage Stephan A. Mayer, Nikolai Constantin Brun, Kamilla Begtrup et al. · New England Journal of Medicine Open access 23 Feb 2005 1,172
22 A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery Dean A. Fergusson, Paul C. Hébert, C. David Mazer et al. · New England Journal of Medicine Open access 14 May 2008 1,156
23 Clinical Practice Guidelines From the AABB Jeffrey L. Carson, Gordon Henry Guyatt, Nancy M. Heddle et al. · JAMA 12 Oct 2016 1,129
24 The Risk Associated with Aprotinin in Cardiac Surgery Dennis T. Mangano, Iulia Cristina Tudor, Cynthia Dietzel · New England Journal of Medicine Open access 25 Jan 2006 1,113
25 The Prospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT) Study John B. Holcomb, Deborah J. del Junco, Erin E. Fox et al. · JAMA Surgery Open access 15 Oct 2012 1,111
26 Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB* Jeffrey L. Carson, Brenda J. Grossman, Steven H Kleinman et al. · Annals of Internal Medicine 3 Jul 2012 1,097
27 Transfusion Strategies for Patients in Pediatric Intensive Care Units Jacques Lacroix, Paul C. Hébert, James S. Hutchison et al. · New England Journal of Medicine Open access 18 Apr 2007 1,094
28 Increased Plasma and Platelet to Red Blood Cell Ratios Improves Outcome in 466 Massively Transfused Civilian Trauma Patients John B. Holcomb, Charles E. Wade, Joel Edmund Michalek et al. · Annals of Surgery Sep 2008 1,092
29 Transfusion Requirements After Cardiac Surgery Ludhmila Abrahão Hajjar, Jean‐Louis Vincent, Filomena Regina Barbosa Gomes Galas et al. · JAMA 12 Oct 2010 1,038
30 Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis Katharine Ker, Phil J Edwards, Pablo Perel et al. · BMJ ReviewOpen access 17 May 2012 1,026
31 Effect of anaemia and cardiovascular disease on surgical mortality and morbidity Jeffrey L. Carson, Amy Duff, Roy M. Poses et al. · The Lancet Open access Oct 1996 1,012
32 Relationship of Blood Transfusion and Clinical Outcomes in Patients With Acute Coronary Syndromes Sunil V. Rao · JAMA 5 Oct 2004 1,011
33 Platelet Transfusion: A Clinical Practice Guideline From the AABB Richard Max Kaufman et al. · Annals of Internal Medicine 10 Nov 2014 1,002
34 An Analysis of Blood Management in Patients Having a Total Hip or Knee Arthroplasty* Benjamin E. Bierbaum, John J. Callaghan, Jorge O. Galante et al. · Journal of Bone and Joint Surgery 1999 991
35 Perioperative Blood Transfusion and Blood Conservation in Cardiac Surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists Clinical Practice Guideline Victor A. Ferraris, Suellen P. Ferraris, Sibu Pada Saha et al. · The Annals of Thoracic Surgery 25 Apr 2007 979
36 Blood Transfusion in Elderly Patients with Acute Myocardial Infarction W.C. Wu, Saif S. Rathore, Yongfei Wang et al. · New England Journal of Medicine Open access 25 Oct 2001 961
37 Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting* Colleen Gorman Koch, Liang Li, Andra Ibrahim Duncan et al. · Critical Care Medicine 13 Apr 2006 957
38 Mild hypothermia increases blood loss and transfusion requirements during total hip arthroplasty Harald Schmied, Audra J. Reiter, Andrea M. Kurz et al. · The Lancet Feb 1996 953
39 The effect of ABO blood group on the diagnosis of von Willebrand disease JC Gill, J Endres-Brooks, PJ Bauer et al. · Blood Jun 1987 947
40 The European Cancer Anaemia Survey (ECAS): A large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients Heinz Ludwig, Simon Van Belle, Peter J. Barrett-Lee et al. · European Journal of Cancer 17 Sep 2004 939
41 Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock Jason L. Sperry et al. · New England Journal of Medicine 25 Jul 2018 921
42 Efficacy of red blood cell transfusion in the critically ill: A systematic review of the literature* Paul Ellis Marik, Howard L. Corwin · Critical Care Medicine Review 26 Aug 2008 916
43 The Effects of Mild Perioperative Hypothermia on Blood Loss and Transfusion Requirement Suman Rajagopalan, Edward J. Mascha, Jie Na et al. · Anesthesiology 2008 915
44 Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock Lars Broksø Holst et al. · New England Journal of Medicine Open access Oct 2014 911
45 Transfusion Medicine — Blood Transfusion Lawrence T. Goodnough, Mark E. Brecher, Michael H. Kanter et al. · New England Journal of Medicine 11 Feb 1999 891
46 International consensus statement on the peri‐operative management of anaemia and iron deficiency Manuel Múñoz, Austin George Acheson, Michael Auerbach et al. · Anaesthesia Open access 20 Dec 2016 876
47 Guidelines for the use of fresh‐frozen plasma, cryoprecipitate and cryosupernatant D F O'Shaughnessy, Claire Atterbury, P. Bolton Maggs et al. · British Journal of Haematology 12 May 2004 845
48 Diagnostic and pathogenetic considerations in transfusion‐related acute lung injury Mark A. Popovsky, S. Breanndan Moore · Transfusion 12 Nov 1985 830
49 Leukocyte Reduction and Ultraviolet B Irradiation of Platelets to Prevent Alloimmunization and Refractoriness to Platelet Transfusions The Trial to Reduce Alloimmunization to Platelets Study Group · New England Journal of Medicine Open access 25 Dec 1997 810
50 Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study Jonathan James Morrison · Archives of Surgery 18 Oct 2011 803

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.