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Most cited papers in Cancer Research and Treatment

What are the most cited papers in Cancer Research and Treatment?

The most cited paper in Cancer Research and Treatment is "The Physical Activity Guidelines for Americans" (Katrina L. Piercy, Richard P. Troiano, Rachel Ballard et al., 2018), with 9,860 citations. Next come "Prevalence of Childhood and Adult Obesity in the United States, 2011-2012" (8,151) and "Health Effects of Overweight and Obesity in 195 Countries over 25 Years" (8,109).

Showing 50 of 100 papers. Every paper with more than 402 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The Physical Activity Guidelines for Americans Katrina L. Piercy, Richard P. Troiano, Rachel Ballard et al. · JAMA Open access 12 Nov 2018 9,860
2 Prevalence of Childhood and Adult Obesity in the United States, 2011-2012 Cynthia L. Ogden, Margaret Deutsch Carroll, Brian K. Kit et al. · JAMA Open access 25 Feb 2014 8,151
3 Health Effects of Overweight and Obesity in 195 Countries over 25 Years The GBD 2015 Obesity Collaborators · New England Journal of Medicine Open access 12 Jun 2017 8,109
4 Sorafenib in Advanced Clear-Cell Renal-Cell Carcinoma Bernard J. Escudier, Tim G Eisen, Walter Michael Stadler et al. · New England Journal of Medicine Open access 10 Jan 2007 4,813
5 Trypan Blue Exclusion Test of Cell Viability Warren Strober · Current Protocols in Immunology Open access Nov 2015 2,619
6 Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence Khayriyyah Mohd Hanafiah, Justina L. Groeger, Abraham D. Flaxman et al. · Hepatology Open access 21 Nov 2012 2,532
7 Metabolic Syndrome in Childhood: Association With Birth Weight, Maternal Obesity, and Gestational Diabetes Mellitus Charlotte M. Boney, Anila Verma, Richard J. Tucker et al. · PEDIATRICS Mar 2005 2,338
8 Global burden of primary liver cancer in 2020 and predictions to 2040 Harriet Rumgay, Melina Arnold, Jacques Ferlay et al. · Journal of Hepatology Open access 5 Oct 2022 2,197
9 Pulmonary Arterial Hypertension in France Marc Humbert, Olivier Sitbon, Ari Chaouat et al. · American Journal of Respiratory and Critical Care Medicine 2 Feb 2006 2,018
10 Advances in Experimental Medicine and Biology G.G. Lunt · Neurochemistry International 1986 1,881
11 Depression and poor glycemic control: a meta-analytic review of the literature. Patrick J. Lustman, Ryan J. Anderson, Kenneth E. Freedland et al. · Diabetes Care Jul 2000 1,861
12 Silver nanoparticles: A new view on mechanistic aspects on antimicrobial activity Nelsón Durán, Marcela Durán, Marcelo Bispo de Jesus et al. · Nanomedicine Nanotechnology Biology and Medicine 24 Dec 2015 1,557
13 Bariatric Surgery Worldwide 2013 Luigi Angrisani, Antonella Santonicola, Paola Iovino et al. · Obesity Surgery 3 Apr 2015 1,496
14 Trends in Long-Term Survival Following Liver Resection for Hepatic Colorectal Metastases Michael A. Choti, James V. Sitzmann, Marcelo F. Tiburi et al. · Annals of Surgery Open access Jun 2002 1,465
15 Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging Suphiya Parveen, Ranjita Misra, Sanjeeb Kumar Sahoo · Nanomedicine Nanotechnology Biology and Medicine 19 Jun 2011 1,438
16 Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications John W. Rasmussen, Ezequiel Martinez, Panagiota Louka et al. · Expert Opinion on Drug Delivery Open access 18 Aug 2010 1,330
17 Multifunctional nanocarriers☆ Vladmir P. Torchilin · Advanced Drug Delivery Reviews 29 Sep 2006 1,266
18 Obesity and the Metabolic Syndrome in Developing Countries Anoop Misra, Lokesh Khurana · The Journal of Clinical Endocrinology & Metabolism Nov 2008 1,234
19 Prevalence of Diabetes and Impaired Fasting Glucose in Adults in the U.S. Population Catherine C. Cowie, Keith Rust, Danita D. Byrd-Holt et al. · Diabetes Care 27 May 2006 1,218
20 Pulmonary Arterial Hypertension David B. Badesch, Gary E. Raskob, C. Gregory Elliott et al. · CHEST Journal 16 Oct 2009 1,187
21 Diagnosis and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents Larry S. Goldman · JAMA 8 Apr 1998 1,095
22 The big picture on nanomedicine: the state of investigational and approved nanomedicine products Michael L. Etheridge, Stephen A. Campbell, Arthur G. Erdman et al. · Nanomedicine Nanotechnology Biology and Medicine Open access 6 Jun 2012 1,079
23 Tumor Progression While on Chemotherapy René Adam, Gérard Pascal, Denis Castaing et al. · Annals of Surgery Open access 25 Nov 2004 1,003
24 Population-Based Study of Sleep-Disordered Breathing as a Risk Factor for Hypertension Terry B Young · Archives of Internal Medicine 11 Aug 1997 941
25 Targeting the EGFR signaling pathway in cancer therapy Parthasarathy Seshacharyulu, Moorthy Palanimuthu Ponnusamy, Dhanya Haridas et al. · Expert Opinion on Therapeutic Targets Open access 2012 937
26 Recurrence of Hepatocellular Cancer After Resection Parissa Tabrizian, Ghalib A. Jibara, Brian Shrager et al. · Annals of Surgery 13 May 2014 931
27 Liposomal Drug Delivery Systems: An Update Review Abdus Samad, Yasmin Sultana, Mohd. Aqil · Current Drug Delivery Oct 2007 899
28 Prevention of Diabetes in Women with a History of Gestational Diabetes: Effects of Metformin and Lifestyle Interventions Robert E. Ratner, Costas A. Christophi, Boyd E. Metzger et al. · The Journal of Clinical Endocrinology & Metabolism Open access Oct 2008 883
29 A Randomized Trial Comparing Radiofrequency Ablation and Surgical Resection for HCC Conforming to the Milan Criteria Jiwei Huang, Lvnan Yan, Zheyu Cheng et al. · Annals of Surgery 23 Nov 2010 853
30 Prospective Cohort Study of Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma in 8510 Patients Kenichi Takayasu, Shigeki Arii, Iwao Ikai et al. · Gastroenterology Open access Aug 2006 813
31 The transferrin receptor and the targeted delivery of therapeutic agents against cancer Tracy R. Daniels‐Wells, Ezequiel Bernabeu, José A. Rodríguez et al. · Biochimica et Biophysica Acta (BBA) - General Subjects Open access 7 Aug 2011 807
32 Ferroptosis: A Novel Anti-tumor Action for Cisplatin Jipeng Guo, Bing-Fei Xu, Qi Han et al. · Cancer Research and Treatment Open access 11 May 2017 798
33 Prevalence and trends of metabolic syndrome among adults in the asia-pacific region: a systematic review Priyanga Diloshini Ranasinghe, Yasith Mathangasinghe, Ranil Jayawardena et al. · BMC Public Health ReviewOpen access 20 Jan 2017 772
34 Effects of Particle Size and Surface Modification on Cellular Uptake and Biodistribution of Polymeric Nanoparticles for Drug Delivery Sneha Avinash Kulkarni, Si‐Shen Feng · Pharmaceutical Research 11 Jan 2013 772
35 Global Prevalence of Hypertension in Children Peige Song, Yan Zhang, Jinyue Yu et al. · Archives of Pediatrics and Adolescent Medicine Open access 7 Oct 2019 753
36 Prevalence and Trends in Obesity and Severe Obesity Among Children in the United States, 1999-2012 Asheley Cockrell Skinner, Joseph A. Skelton · Archives of Pediatrics and Adolescent Medicine 7 Apr 2014 751
37 Obesity prevalence from a European perspective: a systematic review Anne Berghöfer, Tobias Pischon, Thomas Reinhold et al. · BMC Public Health ReviewOpen access 5 Jun 2008 743
38 Maternal Gestational Diabetes, Birth Weight, and Adolescent Obesity Matthew W. Gillman, Sheryl L. Rifas‐Shiman, Catherine S. Berkey et al. · PEDIATRICS Mar 2003 737
39 Recent advances in polymeric drug delivery systems Yong Kiel Sung, Sung Wan Kim · Biomaterials Research Open access 6 Jun 2020 732
40 Influence of Preoperative Chemotherapy on the Risk of Major Hepatectomy for Colorectal Liver Metastases Mehdi Karoui, Christophe Penna, Mohamed Amin-Hashem et al. · Annals of Surgery Open access 21 Dec 2005 722
41 Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma Ronnie Tung‐Ping Poon, Sheung-Tat Fan, Irene Oi‐Lin Ng et al. · Cancer Aug 2000 715
42 Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Julio A. Panza, Philip R. Casino, Crescence M. Kilcoyne et al. · Circulation Open access May 1993 712
43 Prevalence and Predictors of the Metabolic Syndrome in Women with Polycystic Ovary Syndrome David A. Ehrmann, David R. Liljenquist, Kristen Kasza et al. · The Journal of Clinical Endocrinology & Metabolism 2006 712
44 Diagnosis and Treatment of Pulmonary Arterial Hypertension Nicole F. Ruopp, Barbara A. Cockrill · JAMA 12 Apr 2022 698
45 The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review ChandraS Pundir, Ritu Deswal, Vinay Narwal et al. · Journal of Human Reproductive Sciences ReviewOpen access 2020 662
46 Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes LifeCycle Project-Maternal Obesity and Childhood Outcomes Study Group et al. · JAMA Open access 7 May 2019 661
47 Anti-proliferative activity of silver nanoparticles P. V. Asharani, Manoor Prakash Hande, Suresh Valiyaveettil · BMC Cell Biology Open access 17 Sep 2009 660
48 A meta-analysis of randomized controlled trials in pulmonary arterial hypertension Nazzareno Galiè, A. Mañes, Luca Dal Negro et al. · European Heart Journal ReviewOpen access 27 Sep 2008 659
49 Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target Yongmin Yan, Xiangsheng Zuo, Daoyan Wei · Stem Cells Translational Medicine Open access Jul 2015 657
50 Adjuvant sunitinib or sorafenib for high-risk, non-metastatic renal-cell carcinoma (ECOG-ACRIN E2805): a double-blind, placebo-controlled, randomised, phase 3 trial Naomi Balzer Haas et al. · The Lancet Open access 8 Mar 2016 644

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.