Most cited papers in Chemistry and Chemical Engineering
What are the most cited papers in Chemistry and Chemical Engineering?
The most cited paper in Chemistry and Chemical Engineering is "A review on circular economy: the expected transition to a balanced interplay of environmental and economic systems" (Patrizia Ghisellini, Catia Cialani, Sérgio Ulgiati, 2015), with 6,451 citations. Next come "The Conservation of Orbital Symmetry" (4,086) and "A mechanistic study of the antibacterial effect of silver ions onEscherichia coli andStaphylococcus aureus" (4,004).
Showing 50 of 99 papers. Every paper with more than 894 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | A review on circular economy: the expected transition to a balanced interplay of environmental and economic systems Patrizia Ghisellini, Catia Cialani, Sérgio Ulgiati · Journal of Cleaner Production | 16 Sep 2015 | 6,451 |
| 2 | The Conservation of Orbital Symmetry Robert Burns Woodward, Roald Hoffmann · Angewandte Chemie International Edition in English | Nov 1969 | 4,086 |
| 3 | A mechanistic study of the antibacterial effect of silver ions onEscherichia coli andStaphylococcus aureus Qingling Feng, Jing Wu, Gaoqiang Chen et al. · Journal of Biomedical Materials Research | 2000 | 4,004 |
| 4 | AGREE─Analytical GREEnness Metric Approach and Software Francisco Pena‐Pereira, W. Wojnowski, Marek Tobiszewski · Analytical Chemistry | 15 Jun 2020 | 3,989 |
| 5 | Product design and business model strategies for a circular economy Nancy Bocken, Ingrid de Pauw, Conny A. Bakker et al. · Journal of Industrial and Production Engineering | 26 Apr 2016 | 3,901 |
| 6 | Circular Economy: The Concept and its Limitations Jouni Korhonen, Antero Honkasalo, Jyri Seppälä · Ecological Economics | 12 Jul 2017 | 3,897 |
| 7 | Molecular Docking: A Powerful Approach for Structure-Based Drug Discovery Xuan-Yu Meng, Hong‐Xing Zhang, Mihaly Mezei et al. · Current Computer - Aided Drug Design | Jun 2011 | 3,759 |
| 8 | Handbook of Pharmaceutical Excipients Flynn W. Warren · American Journal of Health-System Pharmacy | Aug 1987 | 3,343 |
| 9 | Occurrence, fate and effects of pharmaceutical substances in the environment- A review Bent Halling‐Sørensen, Søren Nors Nielsen, P.F. Lanzky et al. · Chemosphere | 1998 | 3,271 |
| 10 | A quick, direct method for the determination of activation energy from thermogravimetric data Joseph H. Flynn, Leo A. Wall · Journal of Polymer Science Part B Polymer Letters | May 1966 | 3,231 |
| 11 | Automatic Chemical Design Using a Data-Driven Continuous Representation of Molecules Rafael Gómez-Bombarelli, Jennifer N. Wei, David Duvenaud et al. · ACS Central Science | 12 Jan 2018 | 3,200 |
| 12 | Sustainable polymers from renewable resources Yunqing Zhu, Charles Romain, Charlotte K. Williams · Nature | 13 Dec 2016 | 2,764 |
| 13 | Catalytic reactions in ionic liquids. Roger A. Sheldon · Chemical Communications | 17 Oct 2001 | 2,649 |
| 14 | Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods Manvendra Patel, Rahul Kumar, Kamal Kishor et al. · Chemical Reviews | 4 Mar 2019 | 2,639 |
| 15 | Analytical Eco-Scale for assessing the greenness of analytical procedures Agnieszka Gałuszka, Zdzisław M. Migaszewski, Piotr Konieczka et al. · TrAC Trends in Analytical Chemistry | 22 May 2012 | 2,464 |
| 16 | The 12 principles of green analytical chemistry and the SIGNIFICANCE mnemonic of green analytical practices Agnieszka Gałuszka, Zdzisław M. Migaszewski, Jacek Namieśnik · TrAC Trends in Analytical Chemistry | 28 May 2013 | 2,440 |
| 17 | CHEM21 selection guide of classical- and less classical-solvents Denis Prat, A.S. Wells, John D. Hayler et al. · Green Chemistry | 13 Aug 2015 | 2,229 |
| 18 | Origins, Current Status, and Future Challenges of Green Chemistry Paul T. Anastas, Mary M. Kirchhoff · Accounts of Chemical Research | 19 Jun 2002 | 2,215 |
| 19 | Inverse molecular design using machine learning: Generative models for matter engineering Benjamín Sánchez-Lengeling, Alán Aspuru‐Guzik · Science | 26 Jul 2018 | 2,193 |
| 20 | Using carbon dioxide as a building block in organic synthesis Qiang Liu, Lipeng Wu, Ralf Jackstell et al. · Nature Communications | 20 Jan 2015 | 2,180 |
| 21 | Graph theory and molecular orbitals. Total φ-electron energy of alternant hydrocarbons İvan Gutman, Nenad Trinajstić · Chemical Physics Letters | Dec 1972 | 2,180 |
| 22 | The distillation and volatility of ionic liquids Martyn J. Earle, José M. S. S. Esperança, Manuela A. Gîlea et al. · Nature | Feb 2006 | 2,140 |
| 23 | Green and Sustainable Solvents in Chemical Processes Coby J. Clarke, Wei-Chien Tu, Oliver Levers et al. · Chemical Reviews | 4 Jan 2018 | 2,068 |
| 24 | The synchronous-transit method for determining reaction pathways and locating molecular transition states Thomas A. Halgren, William N. Lipscomb · Chemical Physics Letters | Jul 1977 | 2,023 |
| 25 | Green processing using ionic liquids and CO2 Lynnette A. Blanchard, Dan Hâncu, Eric J. Beckman et al. · Nature | May 1999 | 2,005 |
| 26 | Analysis of the reactions used for the preparation of drug candidate molecules John S Carey, David Laffan, Colin Thomson et al. · Organic & Biomolecular Chemistry | 2006 | 1,918 |
| 27 | What is a green solvent? A comprehensive framework for the environmental assessment of solvents Christian Capello, Ulrich Fischer, Konrad Hungerbühler · Green Chemistry | 2007 | 1,902 |
| 28 | Valency and Bonding: A Natural Bond Orbital Donor-Acceptor Perspective Frank Weinhold, Clark R. Landis | 2005 | 1,872 |
| 29 | A short history of ionic liquids—from molten salts to neoteric solvents John S. Wilkes · Green Chemistry | 6 Mar 2002 | 1,674 |
| 30 | The E Factor: fifteen years on Roger A. Sheldon · Green Chemistry | 2007 | 1,668 |
| 31 | Green synthesis of nanoparticles: Current developments and limitations Shuaixuan Ying, Zhenru Guan, Polycarp C. Ofoegbu et al. · Environmental Technology & Innovation | 17 Jan 2022 | 1,640 |
| 32 | Effluent from drug manufactures contains extremely high levels of pharmaceuticals D. G. Joakim Larsson, Cecilia de Pedro, Nicklas Paxéus · Journal of Hazardous Materials | 7 Jul 2007 | 1,609 |
| 33 | CAESAR models for developmental toxicity Antonio Cassano, Alberto Manganaro, Todd M. Martin et al. · Chemistry Central Journal | Jul 2010 | 1,583 |
| 34 | The environmental fate of phthalate esters: A literature review Charles A. Staples, Dennis R. Peterson, Thomas F. Parkerton et al. · Chemosphere | Aug 1997 | 1,578 |
| 35 | Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant Marta Carballa, F. Omil, Juan Manuel Lema et al. · Water Research | 25 Jun 2004 | 1,557 |
| 36 | Key green chemistry research areas—a perspective from pharmaceutical manufacturers David J. C. Constable, Peter J. Dunn, John D. Hayler et al. · Green Chemistry | 2007 | 1,554 |
| 37 | The E factor 25 years on: the rise of green chemistry and sustainability Roger A. Sheldon · Green Chemistry | 30 Sep 2016 | 1,527 |
| 38 | Molecular Orbital Theory for Organic Chemists ANDREW JUN. STREITWIESER · ACS symposium series | 2013 | 1,525 |
| 39 | The Role of Corporations in Achieving Ecological Sustainability Paul Shrivastava · Academy of Management Review | Oct 1995 | 1,435 |
| 40 | Tools and techniques for solvent selection: green solvent selection guides Fergal P. Byrne, Saimeng Jin, Giulia Paggiola et al. · Sustainable Chemical Processes | 23 May 2016 | 1,422 |
| 41 | Advanced organic chemistry Colin Eaborn · Journal of Organometallic Chemistry | Dec 1985 | 1,419 |
| 42 | Intramolecular Reaction in Polycondensations. I. The Theory of Linear Systems Homer Jacobson, WALTER H. STOCKMAYER · The Journal of Chemical Physics | Dec 1950 | 1,408 |
| 43 | Low‐Transition‐Temperature Mixtures (LTTMs): A New Generation of Designer Solvents María Francisco, Adriaan van den Bruinhorst, Maaike C. Kroon · Angewandte Chemie International Edition | 10 Feb 2013 | 1,378 |
| 44 | Sequential Transformations in Organic Chemistry: A Synthetic Strategy with a Future Lutz Friedjan Tietze, Uwe Beifuß · Angewandte Chemie International Edition in English | Feb 1993 | 1,375 |
| 45 | Kinetics of carbamate formation and breakdown Michael Caplow · Journal of the American Chemical Society | Nov 1968 | 1,367 |
| 46 | Pharmaceuticals and personal care products (PPCPs): A review on environmental contamination in China Jin-Lin Liu, Ming Hung Wong · Environment International | 6 Jul 2013 | 1,362 |
| 47 | Simple Selection Criteria for Drug-like Chemical Matter Ingo Muegge, Sarah L. Heald, David R. Brittelli · Journal of Medicinal Chemistry | 15 May 2001 | 1,347 |
| 48 | Emerging pollutants in wastewater: A review of the literature Tiphanie Deblonde, Carole Cossu‐Leguille, Philippe Hartemann · International Journal of Hygiene and Environmental Health | Sep 2011 | 1,324 |
| 49 | AGREEprep – Analytical greenness metric for sample preparation W. Wojnowski, Marek Tobiszewski, Francisco Pena‐Pereira et al. · TrAC Trends in Analytical Chemistry | 14 Feb 2022 | 1,309 |
| 50 | White Analytical Chemistry: An approach to reconcile the principles of Green Analytical Chemistry and functionality Paweł Mateusz Nowak, Renata Wietecha‐Posłuszny, Janusz B. Pawliszyn · TrAC Trends in Analytical Chemistry | 17 Feb 2021 | 1,298 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.