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Most cited papers in Chemotherapy-induced cardiotoxicity and mitigation

Chemotherapy-induced cardiotoxicity and mitigation

What are the most cited papers in Chemotherapy-induced cardiotoxicity and mitigation?

The most cited paper in Chemotherapy-induced cardiotoxicity and mitigation is "Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer" (Sarah C. Darby, Marianne Ewertz, Paul McGale et al., 2013), with 4,034 citations. Next come "Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity" (3,790) and "2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS)" (3,050).

Showing 50 of 96 papers. Every paper with more than 731 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer Sarah C. Darby, Marianne Ewertz, Paul McGale et al. · New England Journal of Medicine Open access 13 Mar 2013 4,034
2 Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity Giorgio Minotti, Pierantonio Menna, Emanuela Salvatorelli et al. · Pharmacological Reviews 28 May 2004 3,790
3 2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS) Alexander Richard Lyon et al. · European Heart Journal Open access167 authors 26 Aug 2022 3,050
4 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines José Luis Zamorano et al. · European Heart Journal Open access 24 Aug 2016 2,586
5 Low-Molecular-Weight Heparin versus a Coumarin for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer Agnes Y. Y. Lee, Mark N. Levine, Ross Ian Baker et al. · New England Journal of Medicine Open access 9 Jul 2003 2,541
6 Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems Oktay Tacar, Pornsak Sriamornsak, Crispin R. Dass · Journal of Pharmacy and Pharmacology 3 Aug 2012 2,482
7 Congestive heart failure in patients treated with doxorubicin Sandra M. Swain, Fredrick S. Whaley, Michael S. Ewer · Cancer Open access 19 May 2003 2,328
8 A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin DavidA Gewirtz · Biochemical Pharmacology Apr 1999 2,263
9 Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea Randall J. Ruch, Shujun Cheng, James E. Klaunig · Carcinogenesis 1989 2,112
10 Identification of the molecular basis of doxorubicin-induced cardiotoxicity Sui Zhang, Xiaobing Liu, Tasneem Bawa‐Khalfe et al. · Nature Medicine 28 Oct 2012 1,988
11 Malignancies, Prothrombotic Mutations, and the Risk of Venous Thrombosis Jeanet W. Blom · JAMA 8 Feb 2005 1,966
12 Doxorubicin-Induced Cardiomyopathy P K Singal, Natasha Iliskovic · New England Journal of Medicine 24 Sep 1998 1,863
13 Expert Consensus for Multimodality Imaging Evaluation of Adult Patients during and after Cancer Therapy: A Report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging Juan Carlos Plana et al. · Journal of the American Society of Echocardiography Open access 27 Aug 2014 1,811
14 Early Detection of Anthracycline Cardiotoxicity and Improvement With Heart Failure Therapy Daniela Maria Cardinale, Alessandro Colombo, Giulia Bacchiani et al. · Circulation 6 May 2015 1,762
15 Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer Emmet O’Brien, Nely Wigler, Moshe Inbar et al. · Annals of Oncology Open access Mar 2004 1,747
16 Doxorubicin pathways Caroline F. Thorn, Connie M. Oshiro, Sharon Marsh et al. · Pharmacogenetics and Genomics Open access 4 Nov 2010 1,663
17 Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism Gary E. Raskob, Nick van Es, Peter B. Verhamme et al. · New England Journal of Medicine Open access 12 Dec 2017 1,633
18 A clinicopathologic analysis of adriamycin cardiotoxicity Edward A. Lefrak, Jan V Pitha, Sidney Rosenheim et al. · Cancer Aug 1973 1,566
19 Shared Risk Factors in Cardiovascular Disease and Cancer Ryan J. Koene, Anna E. Prizment, Anne Hudson Blaes et al. · Circulation Open access 14 Mar 2016 1,529
20 Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update Nigel S. Key, Alok A. Khorana, Nicole M. Kuderer et al. · Journal of Clinical Oncology Open access 5 Aug 2019 1,517
21 Cardiac Dysfunction in the Trastuzumab Clinical Trials Experience Andrew David Seidman, Clifford A. Hudis, Mary Kathryn Pierri et al. · Journal of Clinical Oncology Mar 2002 1,516
22 Doxorubicin: The Good, the Bad and the Ugly Effect Cristina Carvalho, Renato X. Santos, Susana Cardoso et al. · Current Medicinal Chemistry 22 Jul 2009 1,514
23 Role of oxidative stress in cardiovascular diseases Naranjan S. Dhalla, Rana M. Temsah, Thomas Netticadan · Journal of Hypertension Jun 2000 1,469
24 Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies Yanti Octavia, Carlo Gabriele Tocchetti, Kathleen L. Gabrielson et al. · Journal of Molecular and Cellular Cardiology Open access 21 Mar 2012 1,432
25 Late Cardiac Effects of Doxorubicin Therapy for Acute Lymphoblastic Leukemia in Childhood Steven E. Lipshultz, Steven D. Colan, Richard D. Gelber et al. · New England Journal of Medicine 21 Mar 1991 1,430
26 The anti-angiogenic basis of metronomic chemotherapy Robert S. Kerbel, Barton A. Kamen · Nature reviews. Cancer Review Jun 2004 1,409
27 Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA) Andreas Schneeweiß, Stephen Chia, Tamas Hickish et al. · Annals of Oncology Open access 23 May 2013 1,312
28 Incidence of Venous Thromboembolism and Its Effect on Survival Among Patients With Common Cancers Helen K. Chew, Theodore Wun, Danielle Jenine Harvey et al. · Archives of Internal Medicine Open access 27 Feb 2006 1,301
29 Cardiovascular Complications of Cancer Therapy Edward T.H. Yeh, Courtney L. Bickford · Journal of the American College of Cardiology Open access Jun 2009 1,289
30 Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study Joe‐Elie Salem, Ali Manouchehri, Melissa Moey et al. · The Lancet Oncology Open access 12 Nov 2018 1,263
31 Cisplatin Nephrotoxicity: A Review Xin Yao, Kessarin Panichpisal, Neil A. Kurtzman et al. · The American Journal of the Medical Sciences Aug 2007 1,259
32 Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort Daniel A. Mulrooney, Mark W. Yeazel, Toana I. Kawashima et al. · BMJ Open access 8 Dec 2009 1,177
33 Significantly Higher Pathologic Complete Remission Rate After Neoadjuvant Therapy With Trastuzumab, Paclitaxel, and Epirubicin Chemotherapy: Results of a Randomized Trial in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer Aman U. Buzdar, Nuhad K. Ibrahim, Deborah Francis et al. · Journal of Clinical Oncology Mar 2005 1,174
34 Anthracycline-Induced Cardiomyopathy Daniela Maria Cardinale, Alessandro Colombo, Giuseppina Lamantia et al. · Journal of the American College of Cardiology Open access 2010 1,110
35 Doxorubicin Cardiomyopathy Kanu Chatterjee, Jianqing Zhang, Norman Y. Honbo et al. · Cardiology Open access 11 Dec 2009 1,084
36 Use of Myocardial Strain Imaging by Echocardiography for the Early Detection of Cardiotoxicity in Patients During and After Cancer Chemotherapy Paaladinesh Thavendiranathan, Frédéric Poulin, Ki-Dong Lim et al. · Journal of the American College of Cardiology Open access 2 Apr 2014 1,082
37 More ‘Malignant’ Than Cancer? Five-Year Survival Following a First Admission for Heart Failure Simon Stewart, Kate Macintyre, David Hole et al. · European Journal of Heart Failure Open access Jun 2001 1,060
38 Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations Giuseppe Curigliano et al. · Annals of Oncology Open access 17 Jan 2020 1,037
39 Prevention of High-Dose Chemotherapy–Induced Cardiotoxicity in High-Risk Patients by Angiotensin-Converting Enzyme Inhibition Daniela Maria Cardinale, Alessandro Colombo, Maria Teresa Sandri et al. · Circulation 14 Nov 2006 1,033
40 Randomized Study to Assess the Effectiveness of Slow- and Moderate-Release Polymer-Based Paclitaxel-Eluting Stents for Coronary Artery Lesions Antonio Hugo Bezerra Colombo, Janusz Drzewiecki, Adrian Banning et al. · Circulation Open access 4 Aug 2003 1,022
41 Mechanisms of adverse effects of anti-VEGF therapy for cancer Tomomi Kamba, Donald M. McDonald · British Journal of Cancer Open access 22 May 2007 988
42 Anthracycline Chemotherapy and Cardiotoxicity John McGowan, Robin Chung, Angshuman Maulik et al. · Cardiovascular Drugs and Therapy Open access Feb 2017 972
43 Cardiac Toxicity 4 to 20 Years After Completing Anthracycline Therapy Laurel J. Steinherz · JAMA 25 Sep 1991 971
44 Prognostic Value of Troponin I in Cardiac Risk Stratification of Cancer Patients Undergoing High-Dose Chemotherapy Daniela Maria Cardinale, Maria Teresa Sandri, Alessandro Colombo et al. · Circulation 18 May 2004 958
45 Catheter-Based Radiotherapy to Inhibit Restenosis after Coronary Stenting Paul S. Teirstein, Vincent Massullo, Shirish K. Jani et al. · New England Journal of Medicine 12 Jun 1997 945
46 A population-based study of cardiovascular disease mortality risk in US cancer patients Kathleen M. Sturgeon, Lei Deng, Shirley M. Bluethmann et al. · European Heart Journal Open access 9 Oct 2019 944
47 Arterial Thromboembolic Events in Patients with Metastatic Carcinoma Treated with Chemotherapy and Bevacizumab Frank A. Scappaticci, Jamey R. Skillings, Scott N. Holden et al. · JNCI Journal of the National Cancer Institute Open access 8 Aug 2007 938
48 Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management Pushkar Singh Rawat, Aiswarya Jaiswal, Amit Khurana et al. · Biomedicine & Pharmacotherapy Open access 13 May 2021 909
49 Cardiovascular disease competes with breast cancer as the leading cause of death for older females diagnosed with breast cancer: a retrospective cohort study Jennifer L. Patnaik, Tim Byers, Carolyn G DiGuiseppi et al. · Breast Cancer Research Open access Jun 2011 906
50 Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation Yoshihiko Ichikawa, Mohsen Ghanefar, Marina Bayeva et al. · Journal of Clinical Investigation Open access 2014 898

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.