Topic · Circular RNAs in diseases
Most cited papers in Circular RNAs in diseases
What are the most cited papers in Circular RNAs in diseases?
The most cited paper in Circular RNAs in diseases is "MicroRNAs: Target Recognition and Regulatory Functions" (David P. Bartel, 2009), with 20,551 citations. Next come "Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells" (13,088) and "The functions of animal microRNAs" (10,912).
Showing 50 of 100 papers. Every paper with more than 1,602 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | MicroRNAs: Target Recognition and Regulatory Functions David P. Bartel · Cell | 2009 | 20,551 |
| 2 | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology | 7 May 2007 | 13,088 |
| 3 | The functions of animal microRNAs Victor Ambros · Nature | Sep 2004 | 10,912 |
| 4 | MicroRNA expression profiles classify human cancers Jun Tao Lu, Gad A. Getz, Eric Alexander Miska et al. · Nature | Jun 2005 | 9,627 |
| 5 | Circular RNAs are a large class of animal RNAs with regulatory potency Sebastian Memczak, Marvin Jens, Antigoni L Elefsinioti et al. · Nature | 26 Feb 2013 | 8,627 |
| 6 | Natural RNA circles function as efficient microRNA sponges Thomas B. Hansen, Trine I. Jensen, Bettina Hjelm Clausen et al. · Nature | 26 Feb 2013 | 8,603 |
| 7 | Circulating microRNAs as stable blood-based markers for cancer detection Patrick S. Mitchell, Rachael K. Parkin, Evan M. Kroh et al. · Proceedings of the National Academy of Sciences | 28 Jul 2008 | 8,040 |
| 8 | MicroRNAs: small RNAs with a big role in gene regulation Lin He, Gregory James Hannon · Nature Reviews Genetics | 21 Jun 2004 | 7,124 |
| 9 | Oncomirs — microRNAs with a role in cancer Aurora Esquela‐Kerscher, Frank John Slack · Nature reviews. Cancer | 24 Mar 2006 | 7,070 |
| 10 | Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles Marina Colombo, Graça Raposo, Clotilde Théry · Annual Review of Cell and Developmental Biology | 22 Aug 2014 | 6,348 |
| 11 | A microRNA expression signature of human solid tumors defines cancer gene targets Stefano Volinia, George Adrian Calin, Chang‐Gong Liu et al. · Proceedings of the National Academy of Sciences | 3 Feb 2006 | 5,722 |
| 12 | The biogenesis, biology and characterization of circular RNAs Lasse S. Kristensen, Maria Schertz Andersen, Lotte Victoria Winther Stagsted et al. · Nature Reviews Genetics | 8 Aug 2019 | 5,460 |
| 13 | MicroRNA therapeutics: towards a new era for the management of cancer and other diseases Rajesha Rupaimoole, Frank John Slack · Nature Reviews Drug Discovery | 17 Feb 2017 | 4,965 |
| 14 | Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases Xi Chen et al. · Cell Research | 2 Sep 2008 | 4,617 |
| 15 | Circular RNAs are abundant, conserved, and associated with ALU repeats William R. Jeck, Jessica A. Sorrentino, Kai You Wang et al. · RNA | 18 Dec 2012 | 4,612 |
| 16 | MicroRNA Gene Expression Deregulation in Human Breast Cancer Marilena Valeria Iorio, Manuela Ferracin, Chang‐Gong Liu et al. · Cancer Research | 15 Aug 2005 | 4,084 |
| 17 | Metazoan MicroRNAs David P. Bartel · Cell | Mar 2018 | 4,007 |
| 18 | Silencing of microRNAs in vivo with ‘antagomirs’ Jan Krützfeldt, Nikolaus Rajewsky, Ravi S Braich et al. · Nature | 30 Oct 2005 | 3,987 |
| 19 | The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 Philip A. Gregory, Andrew G. Bert, Emily L. Paterson et al. · Nature Cell Biology | 30 Mar 2008 | 3,915 |
| 20 | Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET Héctor Peinado et al. · Nature Medicine | 27 May 2012 | 3,771 |
| 21 | miR-15 and miR-16 induce apoptosis by targeting BCL2 Amelia Cimmino, George Adrian Calin, Muller Fabbri et al. · Proceedings of the National Academy of Sciences | 15 Sep 2005 | 3,542 |
| 22 | The Versatile Role of microRNA-30a in Human Cancer Changqian Wang, Xiang Yang, Yitian Chen et al. · Cellular Physiology and Biochemistry | 2017 | 3,411 |
| 23 | Non-coding RNAs and cancer: microRNAs and beyond Rachel Marie Raia, George A. Călin · Journal of Nucleic Acids Investigation | 11 Mar 2011 | 3,386 |
| 24 | Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis Laura M. Doyle, Michael Zhuo Wang · Cells | 15 Jul 2019 | 3,331 |
| 25 | circRNA Biogenesis Competes with Pre-mRNA Splicing Reut Ashwal-Fluss, Markus Meyer, Nagarjuna Reddy Pamudurti et al. · Molecular Cell | 18 Sep 2014 | 3,328 |
| 26 | MicroRNAs Modulate Hematopoietic Lineage Differentiation Chang‐Zheng Chen, Ling Li, Harvey F. Lodish et al. · Science | 8 Dec 2003 | 3,277 |
| 27 | Long Noncoding RNA and Cancer: A New Paradigm Arunoday Bhan, Milad Soleimani, Subhrangsu S. Mandal · Cancer Research | 12 Jul 2017 | 3,171 |
| 28 | Exon-intron circular RNAs regulate transcription in the nucleus Zhaoyong Li, Chuan Huang, Chun Hui Bao et al. · Nature Structural & Molecular Biology | 9 Feb 2015 | 3,105 |
| 29 | Unique microRNA molecular profiles in lung cancer diagnosis and prognosis Nozomu Yanaihara, Natasha J. Caplen, Elise D. Bowman et al. · Cancer Cell | Mar 2006 | 3,060 |
| 30 | Causes and consequences of microRNA dysregulation in cancer Carlo Maria Croce · Nature Reviews Genetics | 18 Sep 2009 | 3,050 |
| 31 | Detecting and characterizing circular RNAs William R. Jeck, Norman E. Sharpless · Nature Biotechnology | May 2014 | 2,952 |
| 32 | The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation Jian‐Fu Chen, Elizabeth M. Mandel, J. Michael Thomson et al. · Nature Genetics | 25 Dec 2005 | 2,821 |
| 33 | Processing of primary microRNAs by the Microprocessor complex Ahmet M. Denli, Bastiaan B.J. Tops, Ronald H.A. Plasterk et al. · Nature | Nov 2004 | 2,784 |
| 34 | The MicroRNA Spectrum in 12 Body Fluids Jessica A. Weber, David H. Baxter, Shile Zhang et al. · Clinical Chemistry | 17 Sep 2010 | 2,779 |
| 35 | microRNAs as oncogenes and tumor suppressors Baohong Zhang, Xiaoping Pan, George P. Cobb et al. · Developmental Biology | 17 Aug 2006 | 2,771 |
| 36 | The Microprocessor complex mediates the genesis of microRNAs Richard I. Gregory, Kai-ping Yan, Govindasamy Amuthan et al. · Nature | Nov 2004 | 2,758 |
| 37 | microRNA Functions Natascha Bushati, Stephen Michael Cohen · Annual Review of Cell and Developmental Biology | 25 Jun 2007 | 2,714 |
| 38 | A microRNA component of the p53 tumour suppressor network Lin He, Xingyue He, Lee P. Lim et al. · Nature | 6 Jun 2007 | 2,713 |
| 39 | Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed Agnieszka Rybak‐Wolf, Christin Stottmeister, Petar Glažar et al. · Molecular Cell | 25 Apr 2015 | 2,651 |
| 40 | A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA Marcella Cesana, Davide Cacchiarelli, Ivano Legnini et al. · Cell | Oct 2011 | 2,631 |
| 41 | Tumour invasion and metastasis initiated by microRNA-10b in breast cancer Li Ma, Julie Teruya‐Feldstein, Robert A. Weinberg · Nature | 26 Sep 2007 | 2,630 |
| 42 | Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types Julia Salzman, Charles Gawad, Peter Lincoln Wang et al. · PLoS ONE | Feb 2012 | 2,630 |
| 43 | MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells Jennifer Ai-wen Chan, Anna M. Krichevsky, Kenneth S. Kosik · Cancer Research | 15 Jul 2005 | 2,564 |
| 44 | MicroRNA Thomas X. Lu, Marc E. Rothenberg · Journal of Allergy and Clinical Immunology | 23 Oct 2017 | 2,548 |
| 45 | The role of MicroRNAs in human cancer Yong Peng, Carlo Maria Croce · Signal Transduction and Targeted Therapy | 27 Jan 2016 | 2,534 |
| 46 | Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis Ivano Legnini, Gaia Di Timoteo, Francesca Rossi et al. · Molecular Cell | 23 Mar 2017 | 2,386 |
| 47 | The RNA Binding Protein Quaking Regulates Formation of circRNAs Simon J. Conn, Katherine A. Pillman, John Toubia et al. · Cell | Mar 2015 | 2,384 |
| 48 | Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival Junichi Takamizawa, Hiroyuki Konishi, Kiyoshi Yanagisawa et al. · Cancer Research | Jun 2004 | 2,373 |
| 49 | MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts Thomas Thum et al. · Nature | 30 Nov 2008 | 2,368 |
| 50 | Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis Yan Li, Qiupeng Zheng, Chunyang Bao et al. · Cell Research | 3 Jul 2015 | 2,363 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.