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Most cited papers in Connexins and lens biology

What are the most cited papers in Connexins and lens biology?

The most cited paper in Connexins and lens biology is "HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS" (Michael N. Berry, Daniel S. Friend, 1969), with 4,444 citations. Next come "The Lens Opacities Classification System III" (2,929) and "The Retinal Pigment Epithelium in Visual Function" (2,859).

Showing 50 of 101 papers. Every paper with more than 705 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS Michael N. Berry, Daniel S. Friend · The Journal of Cell Biology Open access Dec 1969 4,444
2 The Lens Opacities Classification System III L.T. Chylack · Archives of Ophthalmology Jun 1993 2,929
3 The Retinal Pigment Epithelium in Visual Function Olaf Strauß · Physiological Reviews Review 29 Jun 2005 2,859
4 FINE STRUCTURAL LOCALIZATION OF A BLOOD-BRAIN BARRIER TO EXOGENOUS PEROXIDASE Thomas S. Reese, Morris J. Karnovsky · The Journal of Cell Biology Open access Jul 1967 2,647
5 Occludin: a novel integral membrane protein localizing at tight junctions. Mikio Furuse, Tetsuaki Hirase, Masahiko Itoh et al. · The Journal of Cell Biology Open access 15 Dec 1993 2,574
6 Multifunctional strands in tight junctions Shöichiro Tsukita, Mikio Furuse, Masahiko Itoh · Nature Reviews Molecular Cell Biology Review Apr 2001 2,511
7 JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAIN Milton Brightman, Thomas S. Reese · The Journal of Cell Biology Open access Mar 1969 2,492
8 Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin Mikio Furuse, Kohji Fujita, Takashi Hiiragi et al. · The Journal of Cell Biology Open access 29 Jun 1998 2,097
9 Oxidized Redox State of Glutathione in the Endoplasmic Reticulum CHRISTOPHER K. HWANG, Anthony J. Sinskey, Harvey F. Lodish · Science 11 Sep 1992 1,984
10 The Gap Junction Communication Channel Nalin M. Kumar, Norton B. Gilula · Cell Open access Feb 1996 1,934
11 Alpha-crystallin can function as a molecular chaperone. Joseph Horwitz · Proceedings of the National Academy of Sciences Open access Nov 1992 1,847
12 S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles Rosario Donato · The International Journal of Biochemistry & Cell Biology Jul 2001 1,590
13 Tight junctions: from simple barriers to multifunctional molecular gates Ceniz Zihni, Clare Mills, Karl Matter et al. · Nature Reviews Molecular Cell Biology Review 29 Jun 2016 1,530
14 Claudin-based tight junctions are crucial for the mammalian epidermal barrier Mikio Furuse, Masaki Hata, Kyoko Furuse et al. · The Journal of Cell Biology Open access 11 Mar 2002 1,515
15 Claudins and the Modulation of Tight Junction Permeability Dorothee Günzel, Alan S.L. Yu · Physiological Reviews ReviewOpen access Apr 2013 1,488
16 Connexin 26 mutations in hereditary non-syndromic sensorineural deafness David P. Kelsell, John Dunlop, Howard P. Stevens et al. · Nature May 1997 1,484
17 The tight junction: a multifunctional complex Eveline E. Schneeberger, Robert Dale Lynch · American Journal of Physiology-Cell Physiology 19 May 2004 1,413
18 Endothelial Cell-to-Cell Junctions: Molecular Organization and Role in Vascular Homeostasis Gianfranco Bazzoni, Elisabetta Dejana · Physiological Reviews Review Jul 2004 1,397
19 Small heat shock proteins are molecular chaperones. Ursula Jakob, Matthias Gaestel, Katrin Engel et al. · Journal of Biological Chemistry Open access 1993 1,397
20 ARPE-19, A Human Retinal Pigment Epithelial Cell Line with Differentiated Properties K. C. Dunn, Amy E. Aotaki-Keen, Frances R. Putkey et al. · Experimental Eye Research Feb 1996 1,349
21 Connections with Connexins: the Molecular Basis of Direct Intercellular Signaling Roberto Bruzzone, Thomas W. White, David L. Paul · European Journal of Biochemistry Open access May 1996 1,309
22 Cardiac Malformation in Neonatal Mice Lacking Connexin43 Andrew G. Reaume, Paul A. De Sousa, Sarang Kulkarni et al. · Science 24 Mar 1995 1,254
23 CONNEXINS, CONNEXONS, AND INTERCELLULAR COMMUNICATION Daniel A. Goodenough, Jeffrey A. Goliger, David L. Paul · Annual Review of Biochemistry Jun 1996 1,207
24 Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions Juan Carlos Sáez, Viviana M. Berthoud, María C. Brañes et al. · Physiological Reviews ReviewOpen access Oct 2003 1,183
25 Tight junctions of the blood-brain barrier: development, composition and regulation. Hartwig Wolburg, Andrea Lippoldt · PubMed Jun 2002 1,169
26 Mouse Small eye results from mutations in a paired-like homeobox-containing gene Robert E. Hill, Jack Favor, Brigid L.M. Hogan et al. · Nature 26 Dec 1991 1,164
27 Structural and Functional Diversity of Connexin Genes in the Mouse and Human Genome Klaus Willecke, Jürgen Eiberger, Joachim Degen et al. · Biological Chemistry Open access 15 Jan 2002 1,162
28 Tight junction proteins Lorenza González‐Mariscal, Abigail Betanzos, Porfirio Nava et al. · Progress in Biophysics and Molecular Biology Open access 10 Dec 2002 1,161
29 Induction of reproducible brain infarction by photochemically initiated thrombosis Brant D. Watson, W. Dalton Dietrich, Raul Busto et al. · Annals of Neurology May 1985 1,144
30 Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg 2+ Resorption David B. Simon, Yin Lu, Keith A. Choate et al. · Science 2 Jul 1999 1,141
31 CLAUDINS AND EPITHELIAL PARACELLULAR TRANSPORT Christina M. Van Itallie, James Melvin Anderson · Annual Review of Physiology Review 21 Sep 2005 1,135
32 Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands Kazumasa Morita, Mikio Furuse, Kazushi Fujimoto et al. · Proceedings of the National Academy of Sciences Open access 19 Jan 1999 1,131
33 Connexin43: a protein from rat heart homologous to a gap junction protein from liver. Eric C. Beyer, David L. Paul, D A Goodenough · The Journal of Cell Biology Open access Dec 1987 1,119
34 FRACTURE FACES OF ZONULAE OCCLUDENTES FROM "TIGHT" AND "LEAKY" EPITHELIA Philippa Claude, Daniel A. Goodenough · The Journal of Cell Biology Open access Aug 1973 1,106
35 Gap junctions and the connexin protein family Goran Söhl · Cardiovascular Research 23 Dec 2003 1,006
36 Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer Qing Chen, Adrienne Ann Boire, Xin Jin et al. · Nature Open access 17 May 2016 981
37 Gap junctions: New tools, new answers, new questions Michael V. L. Bennett, Luis Carlos Barrio, Thaddeus A. Bargiello et al. · Neuron Mar 1991 977
38 The VF-14 Earl P. Steinberg · Archives of Ophthalmology May 1994 974
39 A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts Mikio Furuse, Hiroyuki Sasaki, Kazushi Fujimoto et al. · The Journal of Cell Biology Open access 19 Oct 1998 969
40 Multicolor and Electron Microscopic Imaging of Connexin Trafficking Guido M. Gaietta, Thomas J. Deerinck, Stephen Adams et al. · Science 19 Apr 2002 915
41 Necrotic death as a cell fate Wei‐Xing Zong, Craig B. Thompson · Genes & Development Open access 2006 913
42 Oxidative stress‐induced cataract: mechanism of action Abraham Spector · The FASEB Journal Sep 1995 907
43 Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis Dolores D. Mruk, C. Yan Cheng · Endocrine Reviews Oct 2004 904
44 Tight Junction Pore and Leak Pathways: A Dynamic Duo Le Shen, Christopher R. Weber, David Ronan Raleigh et al. · Annual Review of Physiology ReviewOpen access 11 Feb 2011 888
45 Signalling to and from tight junctions Karl Matter, Maria Susana Balda · Nature Reviews Molecular Cell Biology Review 28 Feb 2003 887
46 Age-related nuclear cataract—oxidation is the key Roger J.W. Truscott · Experimental Eye Research 10 Feb 2005 874
47 Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission Nathalie Rouach, Annette Koulakoff, Verónica Abudara et al. · Science 4 Dec 2008 874
48 Endothelial Claudin Kazumasa Morita, Hiroyuki Sasaki, Mikio Furuse et al. · The Journal of Cell Biology Open access 4 Oct 1999 870
49 Intercellular Calcium Signaling in Astrocytes via ATP Release through Connexin Hemichannels Charles E. Stout, James L. Costantin, Christian C. G. Naus et al. · Journal of Biological Chemistry Open access Mar 2002 869
50 Ageing and vision: structure, stability and function of lens crystallins Hans BLOEMENDAL, Wilfried de Jong, Rainer Jaenicke et al. · Progress in Biophysics and Molecular Biology Open access 23 Dec 2003 868

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.