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Most cited papers in Curcumin's Biomedical Applications

Curcumin's Biomedical Applications

What are the most cited papers in Curcumin's Biomedical Applications?

The most cited paper in Curcumin's Biomedical Applications is "Bioavailability of Curcumin: Problems and Promises" (Preetha Anand, Ajaikumar Bahulayan Kunnumakkara, Robert Alan Newman et al., 2007), with 5,518 citations. Next come "Role of reactive oxygen species (ROS) in apoptosis induction" (2,787) and "Curcumin: A Review of Its Effects on Human Health" (2,687).

Showing 50 of 100 papers. Every paper with more than 679 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Bioavailability of Curcumin: Problems and Promises Preetha Anand, Ajaikumar Bahulayan Kunnumakkara, Robert Alan Newman et al. · Molecular Pharmaceutics 14 Nov 2007 5,518
2 Role of reactive oxygen species (ROS) in apoptosis induction Hans‐Uwe Simon, Abdulla Haj-Yehia, Francesca Levi‐Schaffer · APOPTOSIS Nov 2000 2,787
3 Curcumin: A Review of Its Effects on Human Health Susan Joyce Hewlings, Douglas Kalman · Foods Open access 22 Oct 2017 2,687
4 Anticancer potential of curcumin: preclinical and clinical studies. Bharat Bhushan Aggarwal, Anushree Jai Kumar, Alok Chandra Bharti · PubMed May 2003 2,576
5 Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo Fusheng Yang, Giselle P. Lim, Aynun Nahar Begum et al. · Journal of Biological Chemistry Open access 8 Dec 2004 2,331
6 Curcumin as “Curecumin”: From kitchen to clinic Ajay Goel, Ajaikumar Bahulayan Kunnumakkara, Bharat Bhushan Aggarwal · Biochemical Pharmacology 20 Aug 2007 2,222
7 Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials Subash C. Gupta, Sridevi Patchva, Bharat Bhushan Aggarwal · The AAPS Journal Open access 9 Nov 2012 2,109
8 Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Ann‐Lii Cheng et al. · PubMed 10 Dec 2001 2,081
9 Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases Bharat Bhushan Aggarwal, Kuzhuvelil B. Harikumar · The International Journal of Biochemistry & Cell Biology Open access 10 Jul 2008 2,037
10 Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease David Allan Butterfield, Barry B. Halliwell · Nature reviews. Neuroscience ReviewOpen access 8 Feb 2019 2,001
11 Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers Guido Shoba, David C. Joy, Thangam Joseph et al. · Planta Medica May 1998 1,970
12 The Essential Medicinal Chemistry of Curcumin Kathryn M. Nelson, Jayme L. Dahlin, Jonathan Bisson et al. · Journal of Medicinal Chemistry Open access 11 Jan 2017 1,950
13 Antioxidant and radical scavenging properties of curcumin Tuba Parlak Ak, İlhami Gülçın · Chemico-Biological Interactions 8 May 2008 1,941
14 Curcumin: From ancient medicine to current clinical trials Heather Hatcher, Roy P. Planalp, J. Cho et al. · Cellular and Molecular Life Sciences Open access 6 Mar 2008 1,860
15 Gasdermin E suppresses tumour growth by activating anti-tumour immunity Zhibin Zhang, Ying Zhang, Shiyu Xia et al. · Nature Open access 11 Mar 2020 1,791
16 Molecular targets of dietary agents for prevention and therapy of cancer Bharat Bhushan Aggarwal, Shishir Shishodia · Biochemical Pharmacology 24 Feb 2006 1,761
17 Stability of curcumin in buffer solutions and characterization of its degradation products Ying‐Jan Wang, Min‐Hsiung Pan, Ann‐Lii Cheng et al. · Journal of Pharmaceutical and Biomedical Analysis Aug 1997 1,707
18 Pharmacology of Curcuma longa Hermann P. T. Ammon, Martin Wahl · Planta Medica Feb 1991 1,690
19 Multiple biological activities of curcumin: A short review Radha K. Maheshwari, Anoop K. Singh, Jaya P. Gaddipati et al. · Life Sciences 19 Jan 2006 1,670
20 Curcumin: The story so far Ricky A. Sharma, Andreas J. Gescher, William P. Steward · European Journal of Cancer 4 Aug 2005 1,657
21 CURCUMIN: THE INDIAN SOLID GOLD Bharat Bhushan Aggarwal, Chitra Sundaram, Nikita Malani et al. · Advances in experimental medicine and biology Book chapter 6 Aug 2007 1,654
22 Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-κB activation Young‐Joon Surh, Kyung‐Soo Chun, Hyun-Ho Cha et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis Open access Sep 2001 1,625
23 A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes Dongmei Sun, Xiaoying Zhuang, Xiaoyu Xiang et al. · Molecular Therapy Open access 22 Jun 2010 1,582
24 The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse Giselle P. Lim, Teresa Chu, Fusheng Yang et al. · Journal of Neuroscience Open access Nov 2001 1,534
25 The Chemistry of Curcumin: From Extraction to Therapeutic Agent Kavirayani Indira Priyadarsini · Molecules Open access Dec 2014 1,506
26 Dose escalation of a curcuminoid formulation Christopher D. Lao, Mack T. Ruffin, Daniel Paul Normolle et al. · BMC Complementary and Alternative Medicine Open access 17 Mar 2006 1,398
27 ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF CURCUMIN Venugopal Padmanabhan Menon, Adluri Ram Sudheer · Advances in experimental medicine and biology Book chapter 6 Aug 2007 1,398
28 Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane) Sanjaya Singh, Bharat Bhushan Aggarwal · Journal of Biological Chemistry Open access Oct 1995 1,389
29 Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain Xiaoying Zhuang, Xiaoyu Xiang, William E. Grizzle et al. · Molecular Therapy Open access 13 Sep 2011 1,361
30 Molecular mechanisms of N -acetylcysteine actions Muhammad Zafarullah, W. Q. Li, Judith Sylvester et al. · Cellular and Molecular Life Sciences Open access 2003 1,345
31 Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer Navneet Kaur Dhillon, Bharat Bhushan Aggarwal, Robert Alan Newman et al. · Clinical Cancer Research 15 Jul 2008 1,333
32 Oxidative stress and apoptosis Krishnaswamy Kannan, Sushil Kumar Jain · Pathophysiology Open access Sep 2000 1,297
33 A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin Soheil Zorofchian Moghadamtousi, Habsah Abdul Kadir, Pouya Hassandarvish et al. · BioMed Research International Open access 2014 1,272
34 The Advancing of Zinc Oxide Nanoparticles for Biomedical Applications Jinhuan Jiang, Jiang Pi, Jiye Cai · Bioinorganic Chemistry and Applications Open access 5 Jul 2018 1,262
35 Phase I Clinical Trial of Oral Curcumin Ricky A. Sharma, Stephanie A. Euden, Sharon L. Platton et al. · Clinical Cancer Research Open access 15 Oct 2004 1,259
36 Curcumin has potent anti‐amyloidogenic effects for Alzheimer's β‐amyloid fibrils in vitro Kenjiro Ono, Kazuhiro Hasegawa, Hironobu Naiki et al. · Journal of Neuroscience Research 13 Feb 2004 1,254
37 Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Julie S Jurenka · PubMed Jun 2009 1,220
38 Curcumin, an active component of turmeric ( Curcuma longa ), and its effects on health Betül Kocaadam Bozkurt, Nevin Şanlıer · Critical Reviews in Food Science and Nutrition 3 Nov 2015 1,212
39 Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature Preetha Anand, Sherin G. Thomas, Ajaikumar Bahulayan Kunnumakkara et al. · Biochemical Pharmacology 20 Aug 2008 1,208
40 Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets Bharat Bhushan Aggarwal, Bokyung Sung · Trends in Pharmacological Sciences Review 27 Dec 2008 1,146
41 Nitric Oxide Scavenging by Curcuminoids Sreejayan, Mahadev Rao · Journal of Pharmacy and Pharmacology 1997 1,137
42 Curcumin and cancer: An “old-age” disease with an “age-old” solution Preetha Anand, Chitra Sundaram, Sonia Jhurani et al. · Cancer Letters 7 May 2008 1,135
43 Oxygen radical scavenging activity of curcumin Elizabeth Kunchandy, Mahadev Rao · International Journal of Pharmaceutics Feb 1990 1,131
44 Safety and Anti-Inflammatory Activity of Curcumin: A Component of Tumeric ( Curcuma longa ) Nita Chainani‐Wu · The Journal of Alternative and Complementary Medicine Feb 2003 1,105
45 Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy Savita Bisht, Georg Feldmann, Sheetal Soni et al. · Journal of Nanobiotechnology Open access 17 Apr 2007 1,094
46 Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins Ajaikumar Bahulayan Kunnumakkara, Preetha Anand, Bharat Bhushan Aggarwal · Cancer Letters 14 May 2008 1,083
47 Flavonoids as Potential Anti-Inflammatory Molecules: A Review Jameel Mohammed Al-Khayri, Gandasi Ravikumar Sahana, Praveen Nagella et al. · Molecules Open access 2 May 2022 1,082
48 Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action Mithun Rudrapal, Shubham Jagadish Khairnar, Johra Khan et al. · Frontiers in Pharmacology Open access 14 Feb 2022 1,077
49 Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma Reason Wilken, Mysore S. Veena, Marilene B. Wang et al. · Molecular Cancer Open access 7 Feb 2011 1,073
50 Anti-tumour and antioxidant activity of natural curcuminoids A.J. Ruby, Girija Kuttan, Kalapala Vijay Babu et al. · Cancer Letters Jul 1995 1,071

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.