| 1 |
Global Prevalence of Diabetes
Sarah H. Wild, Gojka Roglić, Anders Green et al. · Diabetes Care
|
May 2004 |
15,370 |
| 2 |
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation
K. G. M. M. Alberti, Paul Zimmet, WHO Consultation · Diabetic Medicine
|
Jul 1998 |
15,336 |
| 3 |
Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition
Pouya Saeedi, Inga Petersohn, Paraskevi Salpea et al. · Diabetes Research and Clinical Practice
|
10 Sep 2019 |
10,771 |
| 4 |
Biological insights from 108 schizophrenia-associated genetic loci
Stephan Ripke et al. · Nature
Open access297 authors |
Jul 2014 |
8,181 |
| 5 |
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
Gökhan S. Hotamışlıgil, Narinder S. Shargill, Bruce M. Spiegelman · Science
Open access |
1993 |
7,534 |
| 6 |
Global estimates of the prevalence of diabetes for 2010 and 2030
Jonathan Edward Shaw, Richard A. Sicree, Paul Zimmet · Diabetes Research and Clinical Practice
|
7 Nov 2009 |
7,277 |
| 7 |
Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections
Hilary O.M. King, Ronald E. Aubert, William H. Herman · Diabetes Care
|
Sep 1998 |
6,345 |
| 8 |
Global and societal implications of the diabetes epidemic
Paul Zimmet, K. G. M. M. Alberti, Jonathan Edward Shaw · Nature
Open access |
Dec 2001 |
5,915 |
| 9 |
Global aetiology and epidemiology of type 2 diabetes mellitus and its complications
Yan Zheng, Sylvia H. Ley, Frank B. Hu · Nature Reviews Endocrinology
Review |
8 Dec 2017 |
5,865 |
| 10 |
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology
|
Aug 1995 |
5,571 |
| 11 |
The Pathobiology of Diabetic Complications
Michael Brownlee · Diabetes
|
Jun 2005 |
5,356 |
| 12 |
Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen
A.M. James Shapiro, Jonathan R.T. Lakey, Edmond A. Ryan et al. · New England Journal of Medicine
Open access |
27 Jul 2000 |
5,299 |
| 13 |
Chronic inflammation in the etiology of disease across the life span
David Furman, Judith Campisi, Eric M. Verdin et al. · Nature Medicine
Open access |
Dec 2019 |
4,935 |
| 14 |
Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021
Kanyin Liane Ong et al. · The Lancet
Open access795 authors |
23 Jun 2023 |
4,668 |
| 15 |
Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants
Bin Zhou et al. · The Lancet
Open access514 authors |
Apr 2016 |
4,426 |
| 16 |
IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
David R. Whiting, Leonor Guariguata, Clara Weil et al. · Diabetes Research and Clinical Practice
|
13 Nov 2011 |
4,034 |
| 17 |
β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes
Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes
|
2003 |
4,026 |
| 18 |
Inflammation, stress, and diabetes
Kathryn E. Wellen, Gökhan S. Hotamışlıgil · Journal of Clinical Investigation
Open access |
2 May 2005 |
3,922 |
| 19 |
Type 2 diabetes as an inflammatory disease
Marc Yves Donath, Steven E. Shoelson · Nature reviews. Immunology
Review |
14 Jan 2011 |
3,777 |
| 20 |
C-reactive protein: a critical update
Mark B. Pepys, Gideon Morris Hirschfield · Journal of Clinical Investigation
Open access |
15 Jun 2003 |
3,448 |
| 21 |
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics
|
2001 |
3,417 |
| 22 |
Inflammasomes: mechanism of action, role in disease, and therapeutics
Haitao Guo, Justin Callaway, Jenny P.-Y. Ting · Nature Medicine
Open access |
29 Jun 2015 |
3,293 |
| 23 |
International Expert Committee Report on the Role of the A1C Assay in the Diagnosis of Diabetes
The International Expert Committee · Diabetes Care
Open access |
5 Jun 2009 |
3,211 |
| 24 |
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
Elizabeth A. Tivol, Frank Borriello, Alain Schweitzer et al. · Immunity
Open access |
Nov 1995 |
2,923 |
| 25 |
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
Paul Bastard et al. · Science
Open access752 authors |
24 Sep 2020 |
2,885 |
| 26 |
Trained immunity: A program of innate immune memory in health and disease
Mihai Gheorghe Netea, Leo A. B. Joosten, Eicke Latz et al. · Science
Open access |
21 Apr 2016 |
2,825 |
| 27 |
Systemic Lupus Erythematosus
George C. Tsokos · New England Journal of Medicine
|
Dec 2011 |
2,774 |
| 28 |
Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin
John James Skehel, Don C. Wiley · Annual Review of Biochemistry
Review |
Jun 2000 |
2,734 |
| 29 |
Defining trained immunity and its role in health and disease
Mihai Gheorghe Netea, Jorge Domínguez‐Andrés, Luis Bruno Barreiro et al. · Nature reviews. Immunology
ReviewOpen access |
4 Mar 2020 |
2,707 |
| 30 |
Type 1 diabetes
Mark A. Atkinson, George S. Eisenbarth, Aaron W. Michels · The Lancet
Open access |
25 Jul 2013 |
2,699 |
| 31 |
Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications
Jeffrey S. Flier, Lisa H. Underhill, Michael Brownlee et al. · New England Journal of Medicine
|
19 May 1988 |
2,526 |
| 32 |
The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM
Ralph A. DeFronzo · Diabetes
|
Jun 1988 |
2,485 |
| 33 |
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
Jorge Henao‐Mejia, Eran Elinav, Chengcheng Jin et al. · Nature
Open access |
31 Jan 2012 |
2,464 |
| 34 |
Lactic Dehydrogenase Activity in Blood.
Felix Wröblewski, John S. LaDue · Experimental Biology and Medicine
|
Oct 1955 |
2,453 |
| 35 |
The Inflammasomes: Guardians of the Body
Fabio Martinon, Annick Mayor, Jürg Tschopp · Annual Review of Immunology
Review |
20 Mar 2009 |
2,450 |
| 36 |
Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes
Umut Özcan, Erkan Yılmaz, Lale Özcan et al. · Science
Open access |
24 Aug 2006 |
2,444 |
| 37 |
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Qian Zhang et al. · Science
Open access746 authors |
24 Sep 2020 |
2,421 |
| 38 |
Microencapsulated Islets as Bioartificial Endocrine Pancreas
Franklin Lim, Anthony M. Sun · Science
|
21 Nov 1980 |
2,379 |
| 39 |
Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein–Coupled Receptor FFAR2
Gwen Tolhurst, Helen Heffron, Yu Shan Lam et al. · Diabetes
Open access |
21 Dec 2011 |
2,365 |
| 40 |
The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives
Lei Chen, Dianna J. Magliano, Paul Zimmet · Nature Reviews Endocrinology
Review |
8 Nov 2011 |
2,259 |
| 41 |
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
Yuval Dor, Juliana R. Brown, Olga I. Martinez et al. · Nature
|
May 2004 |
2,237 |
| 42 |
Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic Rats
Carl Robert Morgan, Arnold Lazarow · Diabetes
|
Mar 1963 |
2,218 |
| 43 |
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection
E. John Wherry, Sang‐Jun Ha, Susan M. Kaech et al. · Immunity
Open access |
Oct 2007 |
2,189 |
| 44 |
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
Hironori Ueda et al. · Nature
|
30 Apr 2003 |
2,188 |
| 45 |
Temporal development of the gut microbiome in early childhood from the TEDDY study
Christopher J. Stewart et al. · Nature
Open access |
Oct 2018 |
2,147 |
| 46 |
Hyperglycemic Crises in Adult Patients With Diabetes
Abbas E. Kitabchi, Guillermo E. Umpierrez, John M. Miles et al. · Diabetes Care
Open access |
29 Jun 2009 |
2,088 |
| 47 |
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
Janet Markle, Daniel N. Frank, Steven M. Mortin-Toth et al. · Science
|
18 Jan 2013 |
2,086 |
| 48 |
International Consensus on Use of Continuous Glucose Monitoring
Thomas Danne et al. · Diabetes Care
Open access |
10 Nov 2017 |
2,082 |
| 49 |
B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes
Benoı̂t L. Salomon, Deborah J. Lenschow, Lesley Rhee et al. · Immunity
Open access |
Apr 2000 |
2,076 |
| 50 |
HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
John A. Todd, John I. Bell, Hugh O. McDevitt · Nature
|
Oct 1987 |
2,050 |