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Most cited papers in Diet and metabolism studies

What are the most cited papers in Diet and metabolism studies?

The most cited paper in Diet and metabolism studies is "Two new Later Stone Age sites from the Final Pleistocene in the Falémé Valley, eastern Senegal" (Ndiaye, Matar, Lespez, Laurent, Tribolo, Chantal et al., 2024), with 24,104 citations. Next come "An obesity-associated gut microbiome with increased capacity for energy harvest" (12,679) and "Role of Insulin Resistance in Human Disease" (12,183).

Showing 50 of 98 papers. Every paper with more than 2,350 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Two new Later Stone Age sites from the Final Pleistocene in the Falémé Valley, eastern Senegal Ndiaye, Matar, Lespez, Laurent, Tribolo, Chantal et al. · Monash University Research Portal (Monash University) Open access 28 Mar 2024 24,104
2 An obesity-associated gut microbiome with increased capacity for energy harvest Peter James Turnbaugh, Ruth E. Ley, Michael A. Mahowald et al. · Nature Dec 2006 12,679
3 Role of Insulin Resistance in Human Disease Gerald M. Reaven · Diabetes Dec 1988 12,183
4 Diet rapidly and reproducibly alters the human gut microbiome Lawrence A. David, Corinne F. Maurice, Rachel N. Carmody et al. · Nature Open access 11 Dec 2013 10,461
5 Whole Brain Segmentation Bruce R. Fischl, David H. Salat, Evelina Busa et al. · Neuron Open access 2002 9,165
6 Human gut microbes associated with obesity Ruth E. Ley, Peter James Turnbaugh, Samuel Klein et al. · Nature 20 Dec 2006 8,887
7 AIN-93 Purified Diets for Laboratory Rodents: Final Report of the American Institute of Nutrition Ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet Philip G. Reeves, Forrest Harold Nielsen, George C Fahey Jr · Journal of Nutrition Nov 1993 8,763
8 Human gut microbiome viewed across age and geography Tanya Yatsunenko et al. · Nature Open access 8 May 2012 8,081
9 A core gut microbiome in obese and lean twins Peter James Turnbaugh, Micah Hamady, Tanya Yatsunenko et al. · Nature Open access 30 Nov 2008 7,978
10 Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes Gary D. Wu, Jun Chen, Christian Hoffmann et al. · Science Open access Sep 2011 6,707
11 Metabolic Endotoxemia Initiates Obesity and Insulin Resistance Patrice D. Cani et al. · Diabetes Open access 27 Jun 2007 6,653
12 The metabolic syndrome Robert H. Eckel, KGMM Alberti, Scott M. Grundy et al. · The Lancet 2010 6,328
13 The gut microbiota as an environmental factor that regulates fat storage Fredrik Bäckhed, Hao Ding, Ting Wang et al. · Proceedings of the National Academy of Sciences Open access 25 Oct 2004 6,319
14 Obesity alters gut microbial ecology Ruth E. Ley, Fredrik Bäckhed, Peter James Turnbaugh et al. · Proceedings of the National Academy of Sciences Open access 20 Jul 2005 6,243
15 Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus · Diabetes Care Jul 1997 6,238
16 The Human Microbiome Project Peter James Turnbaugh, Ruth E. Ley, Micah Hamady et al. · Nature Open access 17 Oct 2007 6,235
17 THE [ 14 C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT 1 Louis Sokoloff, Martin Reivich, Charles J. Kennedy et al. · Journal of Neurochemistry May 1977 6,043
18 Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein and Amino Acids Paula R. Trumbo, Sandra A. Schlicker, Allison A. Yates et al. · Journal of the American Dietetic Association Nov 2002 6,003
19 Global and societal implications of the diabetes epidemic Paul Zimmet, K. G. M. M. Alberti, Jonathan Edward Shaw · Nature Open access Dec 2001 5,915
20 Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa Carlotta De Filippo, Duccio Cavalieri, Monica Di Paola et al. · Proceedings of the National Academy of Sciences Open access 2 Aug 2010 5,726
21 Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease Zeneng Wang, Elizabeth Klipfell, Brian J. Bennett et al. · Nature Open access Apr 2011 5,702
22 Obesity: global epidemiology and pathogenesis Matthias Blüher · Nature Reviews Endocrinology Review 27 Feb 2019 5,200
23 The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism Gijs den Besten, Karen van Eunen, Albert Kornelis Groen et al. · Journal of Lipid Research Open access 3 Jul 2013 5,091
24 Richness of human gut microbiome correlates with metabolic markers Emmanuelle Le Chatelier et al. · Nature Open access 27 Aug 2013 4,843
25 Obesity as a medical problem Peter G Kopelman · Nature Apr 2000 4,838
26 Gut microbiota in human metabolic health and disease Yong Fan, Oluf Borbye Pedersen · Nature Reviews Microbiology ReviewOpen access 4 Sep 2020 4,818
27 Metagenomic Analysis of the Human Distal Gut Microbiome Steven R. Gill, Mihai Pop, Robert T. DeBoy et al. · Science Open access Jun 2006 4,702
28 Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease Ralph A. DeFronzo, Eleuterio Ferrannini · Diabetes Care Mar 1991 4,568
29 Functional interactions between the gut microbiota and host metabolism Valentina Tremaroli, Fredrik Bäckhed · Nature Sep 2012 4,479
30 Adherence to a Mediterranean Diet and Survival in a Greek Population Antonia Trichopoulou, Tina Costacou, Christina Bamia et al. · New England Journal of Medicine 25 Jun 2003 4,440
31 Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria Bruno Dubois, Howard Feldman, Claudia Jacova et al. · The Lancet Neurology 10 Jul 2007 4,440
32 Predicting Obesity in Young Adulthood from Childhood and Parental Obesity Robert C. Whitaker, Jeffrey A. Wright, MARGARET SULLIVAN PEPE et al. · New England Journal of Medicine Open access 25 Sep 1997 4,434
33 REPRODUCIBILITY AND VALIDITY OF A SEMIQUANTITATIVE FOOD FREQUENCY QUESTIONNAIRE Walter Churchill Willett, Laura Sampson, Meir J. Stampfer et al. · American Journal of Epidemiology Jul 1985 4,350
34 The importance of the ratio of omega-6/omega-3 essential fatty acids Artemis P. Simopoulos · Biomedicine & Pharmacotherapy Oct 2002 4,197
35 The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects G. Blessed, B. E. Tomlinson, Martin Roth · The British Journal of Psychiatry Jul 1968 4,144
36 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults Michael D. Jensen, Donna H. Ryan, Caroline M. Apovian et al. · Journal of the American College of Cardiology Open access 12 Nov 2013 4,059
37 Glycemic index of foods: a physiological basis for carbohydrate exchange David J.A. Jenkins, Thomas M. S. Wolever, R H Taylor et al. · American Journal of Clinical Nutrition Mar 1981 3,872
38 Evolution of Mammals and Their Gut Microbes Ruth E. Ley, Micah Hamady, Catherine Lozupone et al. · Science Open access 22 May 2008 3,862
39 Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice Vanessa K. Ridaura et al. · Science Open access 5 Sep 2013 3,861
40 Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism Douglas J. Morrison, Tom Preston · Gut Microbes Open access 10 Mar 2016 3,851
41 The Impact of the Gut Microbiota on Human Health: An Integrative View José Carlos Clemente, Luke K. Ursell, Laura Wegener Parfrey et al. · Cell Open access Mar 2012 3,818
42 Obesity David William Haslam, W. P. T. James · The Lancet Oct 2005 3,797
43 Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis Jessica M. Yano, Kristie B. Yu, Gregory P. Donaldson et al. · Cell Open access Apr 2015 3,664
44 National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants Goodarz Danaei, Mariel McKenzie Finucane, Yuan Lu et al. · The Lancet 28 Jun 2011 3,607
45 Inflammaging: a new immune–metabolic viewpoint for age-related diseases Claudio Franceschi, Paolo Garagnani, Paolo Parini et al. · Nature Reviews Endocrinology ReviewOpen access 25 Jul 2018 3,594
46 Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) Melanie J. Davies, David A. D’Alessio, JUDITH E. FRADKIN et al. · Diabetes Care Open access 5 Oct 2018 3,565
47 Neuropathological Alterations in Alzheimer Disease Alberto Serrano‐Pozo, Matthew P. Frosch, Eliezer Masliah et al. · Cold Spring Harbor Perspectives in Medicine Open access Sep 2011 3,445
48 Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life Fredrik Bäckhed et al. · Cell Host & Microbe Open access May 2015 3,443
49 European Guidelines for Obesity Management in Adults Volkan Demirhan Yumuk, Constantine Tsigos, Martin Fried et al. · Obesity Facts Open access 2015 3,432
50 DISCONNEXION SYNDROMES IN ANIMALS AND MAN Norman Geschwind · Brain 1965 3,430

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.