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Most cited papers in Dietary Effects on Health

What are the most cited papers in Dietary Effects on Health?

The most cited paper in Dietary Effects on Health is "Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin" (Diabetes Prevention Program Research Group, 2002), with 19,192 citations. Next come "An obesity-associated gut microbiome with increased capacity for energy harvest" (12,679) and "Human gut microbes associated with obesity" (8,887).

Showing 50 of 100 papers. Every paper with more than 940 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin Diabetes Prevention Program Research Group · New England Journal of Medicine Open access 7 Feb 2002 19,192
2 An obesity-associated gut microbiome with increased capacity for energy harvest Peter James Turnbaugh, Ruth E. Ley, Michael A. Mahowald et al. · Nature Dec 2006 12,679
3 Human gut microbes associated with obesity Ruth E. Ley, Peter James Turnbaugh, Samuel Klein et al. · Nature 20 Dec 2006 8,887
4 Revised Estimates for the Number of Human and Bacteria Cells in the Body Ron Sender, Shai Fuchs, Ron Milo · PLoS Biology Open access 19 Aug 2016 5,258
5 The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism Gijs den Besten, Karen van Eunen, Albert Kornelis Groen et al. · Journal of Lipid Research Open access 3 Jul 2013 5,091
6 Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice Vanessa K. Ridaura et al. · Science Open access 5 Sep 2013 3,861
7 Inflammaging: a new immune–metabolic viewpoint for age-related diseases Claudio Franceschi, Paolo Garagnani, Paolo Parini et al. · Nature Reviews Endocrinology ReviewOpen access 25 Jul 2018 3,594
8 Enhanced Recovery After Surgery Olle H. Ljungqvist, Michael J. Scott, Kenneth C. H. Fearon · JAMA Surgery 17 Jan 2017 3,575
9 What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases Emanuele Rinninella, Pauline Celine Raoul, Marco Cintoni et al. · Microorganisms Open access 10 Jan 2019 3,481
10 The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice Peter James Turnbaugh, Vanessa K. Ridaura, Jeremiah J. Faith et al. · Science Translational Medicine Open access 11 Nov 2009 3,138
11 Extending Healthy Life Span—From Yeast to Humans Luigi Fontana, Linda Partridge, Valter Daniel Longo · Science Open access 15 Apr 2010 3,087
12 Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis Aurélien Trompette, Eva S. Gollwitzer, Koshika Yadava et al. · Nature Medicine Open access 5 Jan 2014 2,877
13 Geroscience: Linking Aging to Chronic Disease Brian Keith Kennedy, Shelley L. Berger, Anne Sophie Brunet et al. · Cell Open access Nov 2014 2,837
14 Mechanisms underlying the resistance to diet-induced obesity in germ-free mice Fredrik Bäckhed, Jill K. Manchester, Clay F. Semenkovich et al. · Proceedings of the National Academy of Sciences Open access 8 Jan 2007 2,642
15 Cancer is a Preventable Disease that Requires Major Lifestyle Changes Preetha Anand, Ajaikumar B. Kunnumakara, Chitra Sundaram et al. · Pharmaceutical Research Open access 14 Jul 2008 2,639
16 Inflammation, metaflammation and immunometabolic disorders Gökhan S. Hotamışlıgil · Nature 7 Feb 2017 2,533
17 The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease Kassem Makki, Edward C. Deehan, Jens Walter et al. · Cell Host & Microbe Open access Jun 2018 2,525
18 Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice Fred William Turek, Corinne E. Joshu, Akira Kohsaka et al. · Science Open access 21 Apr 2005 2,510
19 Gut microbiome and health: mechanistic insights Willem M. de Vos, Herbert Tilg, Matthias Van Hul et al. · Gut Open access Feb 2022 2,430
20 The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients? Fabien Magne, Martín Gotteland, Léa Gauthier et al. · Nutrients Open access 19 May 2020 2,368
21 The Effects of Dietary Protein Restriction and Blood-Pressure Control on the Progression of Chronic Renal Disease Saulo Klahr, Andrew S. Levey, Gerald J. Beck et al. · New England Journal of Medicine Open access 31 Mar 1994 2,364
22 Adverse metabolic and cardiovascular consequences of circadian misalignment Frank A. J. L. Scheer, Michael F. Hilton, Christos Socrates Mantzoros et al. · Proceedings of the National Academy of Sciences Open access 2 Mar 2009 2,359
23 Diet–microbiota interactions as moderators of human metabolism Justin Laine Sonnenburg, Fredrik Bäckhed · Nature Open access 5 Jul 2016 2,311
24 Rejuvenation of aged progenitor cells by exposure to a young systemic environment Irina M. Conboy, Michael J. Conboy, Amy J. Wagers et al. · Nature Feb 2005 2,311
25 Short-chain fatty acids in control of body weight and insulin sensitivity Emanuel E. Canfora, Johan W. E. Jocken, Ellen E. Blaak · Nature Reviews Endocrinology Review 11 Aug 2015 2,309
26 Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression Graham M. Lord, Giuseppe Matarese, Jane K. Howard et al. · Nature Aug 1998 2,187
27 Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5 Matam Vijay–Kumar, Jesse D. Aitken, Frédéric A. Carvalho et al. · Science Open access 4 Mar 2010 2,107
28 Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans Brian D. Muegge, Justin Kuczynski, Dan Knights et al. · Science Open access 20 May 2011 2,066
29 Changes in Energy Expenditure Resulting from Altered Body Weight Rudolph L. Leibel, MICHAEL S. ROSENBAUM, Jules Hirsch · New England Journal of Medicine Open access 9 Mar 1995 2,018
30 Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet Megumi Hatori, Christopher Vollmers, Amir Zarrinpar et al. · Cell Metabolism Open access 16 May 2012 2,014
31 Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates Frank M. Sacks, George A. Bray, Vincent J. Carey et al. · New England Journal of Medicine Open access 25 Feb 2009 1,978
32 Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk Weifei Zhu, Jill C. Gregory, Elin Org et al. · Cell Open access Mar 2016 1,967
33 Variations in the Prevalence of Obesity Among European Countries, and a Consideration of Possible Causes. John E Blundell, Jennifer Lyn Baker, Emma Boyland et al. · PubMed Open access 2017 1,950
34 Circadian Integration of Metabolism and Energetics Joseph T. Bass, Joseph S. Takahashi · Science Open access 2 Dec 2010 1,930
35 Entrainment of the Circadian Clock in the Liver by Feeding Karl‐Arne Stokkan, Shin Yamazaki, Hajime Tei et al. · Science 19 Jan 2001 1,821
36 Diet-induced extinctions in the gut microbiota compound over generations Erica Dutil Sonnenburg, Samuel A. Smits, Mikhail Tikhonov et al. · Nature Open access 12 Jan 2016 1,809
37 Intestinal permeability – a new target for disease prevention and therapy Stephan C. Bischoff, Giovanni Barbara, Wim A. Buurman et al. · BMC Gastroenterology Open access 17 Nov 2014 1,757
38 mTOR is a key modulator of ageing and age-related disease Simon C. Johnson, Peter S. Rabinovitch, Matt R. Kaeberlein · Nature Open access 15 Jan 2013 1,729
39 Enhanced recovery after surgery: A consensus review of clinical care for patients undergoing colonic resection Kenneth C. H. Fearon, Olle H. Ljungqvist, Maarten von Meyenfeldt et al. · Clinical Nutrition 22 Apr 2005 1,714
40 Antibiotics in early life alter the murine colonic microbiome and adiposity Ilseung Cho, Shingo Yamanishi, Laura M. Cox et al. · Nature Open access Aug 2012 1,648
41 Fasting Compared With Nonfasting Triglycerides and Risk of Cardiovascular Events in Women Sandeep Bansal, Julie E. Buring, Nader Rifai et al. · JAMA 17 Jul 2007 1,639
42 The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study Guangwei Li, Ping Zhang, Jinping Wang et al. · The Lancet May 2008 1,634
43 The genetics of mammalian circadian order and disorder: implications for physiology and disease Joseph S. Takahashi, Hee-Kyung Hong, Caroline H. Ko et al. · Nature Reviews Genetics ReviewOpen access 18 Sep 2008 1,634
44 Effects of Intermittent Fasting on Health, Aging, and Disease Rafael de Cabo, Mark P. Mattson · New England Journal of Medicine 25 Dec 2019 1,615
45 Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention Ruixin Liu et al. · Nature Medicine 19 Jun 2017 1,595
46 Leptin-regulated endocannabinoids are involved in maintaining food intake Vincenzo Di Marzo, Sravan Kumar Goparaju, Lei Wang et al. · Nature Apr 2001 1,572
47 The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43 Ikuo Kimura, Kentaro Ozawa, Daisuke Inoue et al. · Nature Communications Open access 7 May 2013 1,547
48 Facing up to the global challenges of ageing Linda Partridge, Joris Deelen, P. Eline Slagboom · Nature 30 Aug 2018 1,533
49 Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes Elizabeth F. Sutton, Robbie A. Beyl, Kate S. Early et al. · Cell Metabolism Open access 10 May 2018 1,532
50 An insight into gut microbiota and its functionalities Atanu Adak, Mojibur R. Khan · Cellular and Molecular Life Sciences Open access 13 Oct 2018 1,497

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.