Topic · Epilepsy research and treatment
Most cited papers in Epilepsy research and treatment
What are the most cited papers in Epilepsy research and treatment?
The most cited paper in Epilepsy research and treatment is "Modification of seizure activity by electrical stimulation: II. Motor seizure" (Ronald J. Racine, 1972), with 7,266 citations. Next come "ILAE Official Report: A practical clinical definition of epilepsy" (6,110) and "Early Identification of Refractory Epilepsy" (5,229).
Showing 50 of 100 papers. Every paper with more than 1,008 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Modification of seizure activity by electrical stimulation: II. Motor seizure Ronald J. Racine · Electroencephalography and Clinical Neurophysiology | Mar 1972 | 7,266 |
| 2 | ILAE Official Report: A practical clinical definition of epilepsy Robert S. Fisher, Carlos Alberto Acevedo, Alexis A. Arzimanoglou et al. · Epilepsia | Apr 2014 | 6,110 |
| 3 | Early Identification of Refractory Epilepsy Patrick Kwan, Martin J. Brodie · New England Journal of Medicine | 3 Feb 2000 | 5,229 |
| 4 | ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology Ingrid Eileen Scheffer, Samuel Frank Berkovic, Giuseppe Capovilla et al. · Epilepsia | 8 Mar 2017 | 5,051 |
| 5 | Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies Patrick Kwan, Alexis A. Arzimanoglou, Anne T. Berg et al. · Epilepsia | 3 Nov 2009 | 4,888 |
| 6 | Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005–2009 Anne T. Berg, Samuel Frank Berkovic, Martin J. Brodie et al. · Epilepsia | 26 Feb 2010 | 4,391 |
| 7 | Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) Robert S. Fisher, W. van Emde Boas, Warren T. Blume et al. · Epilepsia | 29 Mar 2005 | 3,682 |
| 8 | A Randomized Controlled Trial of Surgery for Temporal Lobe Epilepsy Samuel Wiebe, Warren T. Blume, John P. Girvin et al. · New England Journal of Medicine | 2 Aug 2001 | 3,547 |
| 9 | Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies Josep O. Dalmau, Amy J. Gleichman, Ethan G. Hughes et al. · The Lancet Neurology | 15 Oct 2008 | 3,513 |
| 10 | Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology Robert S. Fisher, Judith Helen Cross, Jacqueline A. French et al. · Epilepsia | 8 Mar 2017 | 3,494 |
| 11 | Contributions of anterior cingulate cortex to behaviour Orrin Devinsky, Martha J. Morrell, Brent Alan Vogt · Brain | Feb 1995 | 3,406 |
| 12 | Surgical Treatment of the Epilepsies Prakash Kotagal · Journal of Clinical Neurophysiology | Jul 1994 | 2,759 |
| 13 | A definition and classification of status epilepticus – Report of the ILAE Task Force on Classification of Status Epilepticus Eugen Trinka, Hannah R. Cock, Dale C. Hesdorffer et al. · Epilepsia | 4 Sep 2015 | 2,449 |
| 14 | Comment on Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) Ettore Beghi, Anne T. Berg, Arturo Carpio et al. · Epilepsia | 28 Sep 2005 | 2,314 |
| 15 | Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs Alfred H. Schinkel, Jasper Smit, Olaf van Tellingen et al. · Cell | May 1994 | 2,298 |
| 16 | A Proposed Diagnostic Scheme for People with Epileptic Seizures and with Epilepsy: Report of the ILAE Task Force on Classification and Terminology Jerome P. Engel · Epilepsia | Jun 2001 | 2,256 |
| 17 | Epilepsy in adults Roland D. Thijs, Rainer Surges, Terence John O'Brien et al. · The Lancet | 26 Jan 2019 | 2,198 |
| 18 | A Rating Scale for Drug-Induced Akathisia Thomas R. E. Barnes · The British Journal of Psychiatry | May 1989 | 2,191 |
| 19 | Incidence of Epilepsy and Unprovoked Seizures in Rochester, Minnesota: 1935–1984 W. Allen Hauser, John Fred Annegers, Leonard T. Kurland · Epilepsia | May 1993 | 2,087 |
| 20 | Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus Stuart M. Zola-Morgan, LR Squire, DG Amaral · Journal of Neuroscience | Oct 1986 | 2,017 |
| 21 | Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy Robert S. Fisher et al. · Epilepsia | 20 Mar 2010 | 1,957 |
| 22 | Prevalence and incidence of epilepsy Kirsten Marie Fiest, Khara M. Sauro, Samuel Wiebe et al. · Neurology | 17 Dec 2016 | 1,910 |
| 23 | The role of inflammation in epilepsy Annamaria Vezzani, Jacqueline A. French, Tamás Bartfai et al. · Nature Reviews Neurology | 7 Dec 2010 | 1,888 |
| 24 | Cyclic variations in EEG during sleep and their relation to eye movements, body motility, and dreaming William C. Dement, Nathaniel Kleitman · Electroencephalography and Clinical Neurophysiology | Nov 1957 | 1,877 |
| 25 | Motor control and aging: Links to age-related brain structural, functional, and biochemical effects Rachael D. Seidler, Jessica A. Bernard, Taritonye B. Burutolu et al. · Neuroscience & Biobehavioral Reviews | 21 Oct 2009 | 1,840 |
| 26 | Metaplasticity: the plasticity of synaptic plasticity Wickliffe C. Abraham, Mark F. Bear · Trends in Neurosciences | Apr 1996 | 1,805 |
| 27 | Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1 Kohichi Tanaka, Kei Watase, Toshiya Manabe et al. · Science | 13 Jun 1997 | 1,776 |
| 28 | The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission1 Ingmar Blümcke et al. · Epilepsia | 10 Nov 2010 | 1,764 |
| 29 | SEMANTIC DEMENTIA John R. Hodges, Karalyn E. Patterson, Susan Oxbury et al. · Brain | 1992 | 1,743 |
| 30 | Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy Yehezkel Ben‐Ari · Neuroscience | Feb 1985 | 1,733 |
| 31 | Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome Orrin Devinsky, Judith Helen Cross, Linda Laux et al. · New England Journal of Medicine | 24 May 2017 | 1,708 |
| 32 | Presurgical evaluation of epilepsy Felix Rosenow · Brain | Sep 2001 | 1,695 |
| 33 | Guidelines for the Evaluation and Management of Status Epilepticus Gretchen M. Brophy, RODNEY D. BELL, Jan Claassen et al. · Neurocritical Care | 23 Apr 2012 | 1,630 |
| 34 | The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam Berkley A. Lynch, Nathalie Lambeng, Karl H. Nocka et al. · Proceedings of the National Academy of Sciences | 21 Jun 2004 | 1,624 |
| 35 | De novo mutations in epileptic encephalopathies Epilepsy Phenome/Genome Project · Nature | 9 Aug 2013 | 1,565 |
| 36 | Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs Zhibin ZC Chen, Martin J. Brodie, Danny Liew et al. · JAMA Neurology | 26 Dec 2017 | 1,562 |
| 37 | The economic cost of brain disorders in Europe Jes Olesen, Anders Gustavsson, Mikael Svensson et al. · European Journal of Neurology | 19 Dec 2011 | 1,543 |
| 38 | β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression Jeffrey D. Rothstein, Sarjubhai A. Patel, Melissa R. Regan et al. · Nature | 2005 | 1,525 |
| 39 | Two cortical systems for memory-guided behaviour Charan Ranganath, Maureen Ritchey · Nature reviews. Neuroscience | 20 Sep 2012 | 1,517 |
| 40 | Close Interrelation of Motor Development and Cognitive Development and of the Cerebellum and Prefrontal Cortex Adele Diamond · Child Development | 2000 | 1,488 |
| 41 | Willful Modulation of Brain Activity in Disorders of Consciousness Martin M. Monti, Audrey Vanhaudenhuyse, Martin R. Coleman et al. · New England Journal of Medicine | 3 Feb 2010 | 1,474 |
| 42 | Estimation of the burden of active and life‐time epilepsy: A meta‐analytic approach Anthony K. Ngugi, Christian Bottomley, Immo Kleinschmidt et al. · Epilepsia | 7 Jan 2010 | 1,467 |
| 43 | The Epidemiology of Epilepsy Ettore Beghi · Neuroepidemiology | 18 Dec 2019 | 1,442 |
| 44 | The use of c-fos as a metabolic marker in neuronal pathway tracing Mike Dragunow, Richard L. M. Faull · Journal of Neuroscience Methods | Sep 1989 | 1,430 |
| 45 | Physiological and pathophysiological roles of excitatory amino acids during central nervous system development John W. McDonald, Michael V. Johnston · Brain Research Reviews | 1990 | 1,429 |
| 46 | Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence? Irwin Feinberg · Journal of Psychiatric Research | 1982 | 1,411 |
| 47 | Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function Vassilios D. Papadopoulos, Mario Baraldi, Tomás R. Guilarte et al. · Trends in Pharmacological Sciences | 7 Jul 2006 | 1,400 |
| 48 | The Health Anxiety Inventory: development and validation of scales for the measurement of health anxiety and hypochondriasis Paul Martin Salkovskis, Katharine A. Rimes, Hilary M. C. Warwick et al. · Psychological Medicine | Jul 2002 | 1,380 |
| 49 | Chronic parkinsonism secondary to intravenous injection of meperidine analogues Glenn Craig Davis, Adrian C. Williams, Sanford P. Markey et al. · Psychiatry Research | Dec 1979 | 1,375 |
| 50 | Diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment Caroline Schnakers, Audrey Vanhaudenhuyse, Joseph T. Giacino et al. · BMC Neurology | 21 Jul 2009 | 1,371 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.