Most cited papers in Exercise and Physiological Responses
What are the most cited papers in Exercise and Physiological Responses?
The most cited paper in Exercise and Physiological Responses is "An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress" (Heather P. Harding, Yuhong Zhang, Huiquing Zeng et al., 2003), with 3,400 citations. Next come "Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human" (3,365) and "The anti-inflammatory effect of exercise" (3,096).
Showing 50 of 100 papers. Every paper with more than 968 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress Heather P. Harding, Yuhong Zhang, Huiquing Zeng et al. · Molecular Cell | Mar 2003 | 3,400 |
| 2 | Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human Jun Wu, Pontus Boström, Lauren Marie Sparks et al. · Cell | Jul 2012 | 3,365 |
| 3 | The anti-inflammatory effect of exercise Anne Marie Winther Petersen, Bente Klarlund Pedersen · Journal of Applied Physiology | 16 Mar 2005 | 3,096 |
| 4 | Dietary Carcinogens and Anticarcinogens Bruce N. Ames · Science | 23 Sep 1983 | 2,987 |
| 5 | Muscles, exercise and obesity: skeletal muscle as a secretory organ Bente Klarlund Pedersen, Mark Anthony Febbraio · Nature Reviews Endocrinology | 3 Apr 2012 | 2,921 |
| 6 | Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein Mark Stuart Anderson, Emily S. Venanzi, Ludger Klein et al. · Science | 14 Nov 2002 | 2,499 |
| 7 | Skeletal Muscle Fatigue: Cellular Mechanisms David G. Allen, Graham D. Lamb, Håkan Westerblad · Physiological Reviews | 2008 | 2,483 |
| 8 | The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease Michael W. Gleeson, NICOLETTE CLAIRE BISHOP, David J. Stensel et al. · Nature reviews. Immunology | 5 Aug 2011 | 2,480 |
| 9 | Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production Scott K. Powers, Malcolm Joseph Jackson · Physiological Reviews | Oct 2008 | 2,447 |
| 10 | Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6 Bente Klarlund Pedersen, Mark Anthony Febbraio · Physiological Reviews | Oct 2008 | 2,368 |
| 11 | Brown and beige fat: development, function and therapeutic potential Matthew J. Harms, Patrick Seale · Nature Medicine | 29 Sep 2013 | 2,360 |
| 12 | Nrf2-Keap1 signaling in oxidative and reductive stress Ilaria Bellezza, Ileana Giambanco, Alba Minelli et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 27 Feb 2018 | 2,083 |
| 13 | Method for the measurement of antioxidant activity in human fluids D Koraćević, G Koracevic, V Djordjevic et al. · Journal of Clinical Pathology | May 2001 | 1,984 |
| 14 | Fundamentals of Resistance Training: Progression and Exercise Prescription William J. Kraemer, Nicholas A. Ratamess · Medicine & Science in Sports & Exercise | Apr 2004 | 1,983 |
| 15 | Heat Stroke Abderrezak Bouchama, James P. Knöchel · New England Journal of Medicine | 20 Jun 2002 | 1,887 |
| 16 | Unexpected evidence for active brown adipose tissue in adult humans Jan Nedergaard, Tore Bengtsson, Barbara Cannon · American Journal of Physiology-Endocrinology and Metabolism | 2 May 2007 | 1,818 |
| 17 | The Gross Composition of the Body William E. Siri · Advances in biological and medical physics | 1956 | 1,771 |
| 18 | Exercise and the Immune System: Regulation, Integration, and Adaptation Bente Klarlund Pedersen, Laurie Hoffman‐Goetz · Physiological Reviews | Jul 2000 | 1,704 |
| 19 | Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia Christophe Fleury, Maria Neverova, Sheila Collins et al. · Nature Genetics | Mar 1997 | 1,647 |
| 20 | Brown adipose tissue activity controls triglyceride clearance Alexander Bartelt, Oliver T. Bruns, Rudolph Reimer et al. · Nature Medicine | 23 Jan 2011 | 1,642 |
| 21 | Stress revisited: A critical evaluation of the stress concept Jaap M. Koolhaas, Alessandro Bartolomucci, Bauke Buwalda et al. · Neuroscience & Biobehavioral Reviews | 12 Feb 2011 | 1,634 |
| 22 | HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine Alexzander A. A. Asea, Stine‐Kathrein Kraeft, Evelyn A. Kurt‐Jones et al. · Nature Medicine | Apr 2000 | 1,620 |
| 23 | Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading Michael Kjær · Physiological Reviews | 25 Mar 2004 | 1,586 |
| 24 | Antioxidants prevent health-promoting effects of physical exercise in humans Michael Ristow, Kim Zarse, Andreas Oberbach et al. · Proceedings of the National Academy of Sciences | 11 May 2009 | 1,583 |
| 25 | Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid 1 Susan K. Fried, Dove A. Bunkin, Andrew S. Greenberg · The Journal of Clinical Endocrinology & Metabolism | Mar 1998 | 1,530 |
| 26 | Biochemical Adaptations in Muscle John O. Holloszy · Journal of Biological Chemistry | May 1967 | 1,518 |
| 27 | Adverse Events Associated with Testosterone Administration Shehzad Basaria et al. · New England Journal of Medicine | 30 Jun 2010 | 1,499 |
| 28 | FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells Jinghui Zhao, Jeffrey J. Brault, Andreas Schild et al. · Cell Metabolism | Dec 2007 | 1,488 |
| 29 | The Science and Translation of Lactate Shuttle Theory George A. Brooks · Cell Metabolism | Apr 2018 | 1,471 |
| 30 | Exercise-Induced Muscle Damage in Humans Priscilla M. Clarkson, Monica J. Hubal · American Journal of Physical Medicine & Rehabilitation | Nov 2002 | 1,458 |
| 31 | Hormonal Responses and Adaptations to Resistance Exercise and Training William J. Kraemer, Nicholas A. Ratamess · Sports Medicine | 2005 | 1,403 |
| 32 | Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications Uwe Proske, David L. Morgan · The Journal of Physiology | Dec 2001 | 1,395 |
| 33 | Inflammatory processes in muscle injury and repair James G. Tidball · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology | 6 Jan 2005 | 1,376 |
| 34 | IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice Dongsheng Cai, J. Daniel Frantz, Nicholas E. Tawa et al. · Cell | Oct 2004 | 1,369 |
| 35 | Neuropilin-1 is a host factor for SARS-CoV-2 infection James L. Daly et al. · Science | 20 Oct 2020 | 1,363 |
| 36 | The compelling link between physical activity and the body's defense system David Christopher Nieman, Laurel M. Wentz · Journal of sport and health science/Journal of Sport and Health Science | 16 Nov 2018 | 1,350 |
| 37 | Delayed Onset Muscle Soreness Karoline Cheung, Patria Anne Hume, Linda Maxwell · Sports Medicine | 2003 | 1,348 |
| 38 | Effects of stress on immune function: the good, the bad, and the beautiful Firdaus S. Dhabhar · Immunologic Research | May 2014 | 1,346 |
| 39 | Membrane organization of the dystrophin-glycoprotein complex James M. Ervasti, Kevin P. Campbell · Cell | Sep 1991 | 1,343 |
| 40 | UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality Helena M. Feldmann, Valeria Golozoubova, Barbara Cannon et al. · Cell Metabolism | Feb 2009 | 1,335 |
| 41 | The Yo-Yo Intermittent Recovery Test: Physiological Response, Reliability, and Validity Peter Krustrup, Magni Mohr, Tommas Amstrup et al. · Medicine & Science in Sports & Exercise | Apr 2003 | 1,295 |
| 42 | Relationship of Interleukin-6 and Tumor Necrosis Factor- With Muscle Mass and Muscle Strength in Elderly Men and Women: The Health ABC Study Marjolein Visser, Marco Pahor, Dennis R. Taaffe et al. · The Journals of Gerontology Series A | May 2002 | 1,286 |
| 43 | Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial. Ronald J. Sigal, Glen Patrick Kenny, Normand G. Boulé et al. · PubMed | 18 Sep 2007 | 1,278 |
| 44 | TRPA1 mediates formalin-induced pain Colleen R. McNamara, Josh Mandel-Brehm, Diana M. Bautista et al. · Proceedings of the National Academy of Sciences | 8 Aug 2007 | 1,274 |
| 45 | Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota Chih‐Jung Chang, Chuan-Sheng Lin, Chia‐Chen Lu et al. · Nature Communications | 23 Jun 2015 | 1,273 |
| 46 | Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice Patrick Seale, Heather M. Conroe, Jennifer L. Estall et al. · Journal of Clinical Investigation | Dec 2010 | 1,272 |
| 47 | A laser-engraved wearable sensor for sensitive detection of uric acid and tyrosine in sweat Yiran Yang, Yu Song, Xiangjie Bo et al. · Nature Biotechnology | 25 Nov 2019 | 1,268 |
| 48 | Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes Nataša Petrovič, Tomas B. Waldén, Irina G. Shabalina et al. · Journal of Biological Chemistry | 22 Dec 2009 | 1,267 |
| 49 | Monitoring training in athletes with reference to overtraining syndrome Carl Foster · Medicine & Science in Sports & Exercise | Jul 1998 | 1,243 |
| 50 | A Special Population of Regulatory T Cells Potentiates Muscle Repair Dalia Burzyn, Wilson F. Kuswanto, Dmitriy Kolodin et al. · Cell | Dec 2013 | 1,240 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.