Science Explorer Back to mapMap

Most cited papers in Flavonoids in Medical Research

What are the most cited papers in Flavonoids in Medical Research?

The most cited paper in Flavonoids in Medical Research is "Important Flavonoids and Their Role as a Therapeutic Agent" (Asad Ullah, Sidra Munir, Syed Lal Badshah et al., 2020), with 1,691 citations. Next come "The Flavonoids: Advances in Research." (1,430) and "The Therapeutic Potential of Apigenin" (1,248).

Showing 50 of 99 papers. Every paper with more than 315 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Important Flavonoids and Their Role as a Therapeutic Agent Asad Ullah, Sidra Munir, Syed Lal Badshah et al. · Molecules Open access 10 Nov 2020 1,691
2 The Flavonoids: Advances in Research. P. Mick Richardson, Jeffrey B. Harborne, T. J. Mabry · Brittonia 1984 1,430
3 The Therapeutic Potential of Apigenin Bahare Salehi, Alessandro Venditti, Mehdi Sharifi‐Rad et al. · International Journal of Molecular Sciences Open access 15 Mar 2019 1,248
4 Flavonoids: Promising anticancer agents Wenying Ren, Zhenhua Qiao, Hongwei Wang et al. · Medicinal Research Reviews 15 Apr 2003 1,157
5 Flavonoids as Potential Anti-Inflammatory Molecules: A Review Jameel Mohammed Al-Khayri, Gandasi Ravikumar Sahana, Praveen Nagella et al. · Molecules Open access 2 May 2022 1,082
6 Anti-inflammatory Plant Flavonoids and Cellular Action Mechanisms Hyun Pyo Kim, Kun Ho Son, Hyeun Wook Chang et al. · Journal of Pharmacological Sciences Open access 2004 1,017
7 New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin Min Li‐Weber · Cancer Treatment Reviews 12 Nov 2008 903
8 Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress Qing Zhang, Jia Liu, Huxinyue Duan et al. · Journal of Advanced Research Open access 6 Jul 2021 837
9 Apigenin: A Promising Molecule for Cancer Prevention Sanjeev Shukla, Sanjay Gupta · Pharmaceutical Research Open access 19 Mar 2010 827
10 Salidroside Attenuates Ventilation Induced Lung Injury via SIRT1-Dependent Inhibition of NLRP3 Inflammasome. Yan Wang, Chu-Fan Xu, Yu-Jian Liu et al. · PubMed 2017 821
11 Sunitinib Versus Sorafenib in Advanced Hepatocellular Cancer: Results of a Randomized Phase III Trial Ann‐Lii Cheng, Yoon‐Koo Kang, Deng‐Yn Lin et al. · Journal of Clinical Oncology Open access Oct 2013 778
12 Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science Yuening Xiang, Zimu Guo, Pengfei Zhu et al. · Cancer Medicine Open access 3 Apr 2019 776
13 Flavonoids in Cancer and Apoptosis Mariam Abotaleb, Samson Mathews Samuel, Elizabeth Varghese et al. · Cancers Open access 28 Dec 2018 757
14 Natural Polyphenols for Prevention and Treatment of Cancer Yue Zhou, Jie Zheng, Ya Li et al. · Nutrients Open access 22 Aug 2016 747
15 Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways Sonia Ramos · Molecular Nutrition & Food Research Open access 24 Apr 2008 699
16 Deglycosylation by small intestinal epithelial cell ?-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans Kitti N�meth, Geoff W. Plumb, Jean‐Guy Berrin et al. · European Journal of Nutrition Feb 2003 671
17 Pharmacological effects of gallic acid in health and diseases: A mechanistic review. Niloofar Kahkeshani, Fatemeh Farzaei, Maryam Fotouhi et al. · PubMed Open access Mar 2019 658
18 The antitumor activities of flavonoids. Chithan Kandaswami, Chithan Kanadaswami, Lung‐ta Lee et al. · PubMed 18 Oct 2005 654
19 Antioxidant and free radical scavenging activity of Spondias pinnata Bibhabasu Hazra, Santanu Biswas, Nripendranath Mandal · BMC Complementary and Alternative Medicine Open access Dec 2008 644
20 Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans Fu Yang, Ling Zhang, Xisong Huo et al. · Hepatology 18 Jul 2011 640
21 Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi Zhonghong Gao, Kaixun Huang, Xiangliang Yang et al. · Biochimica et Biophysica Acta (BBA) - General Subjects Nov 1999 613
22 Anti-inflammatory activity of natural dietary flavonoids Min‐Hsiung Pan, Ching‐Shu Lai, Chi‐Tang Ho · Food & Function 2010 606
23 Potential Role of Flavonoids in Treating Chronic Inflammatory Diseases with a Special Focus on the Anti-Inflammatory Activity of Apigenin Rashida Ginwala, Raina Bhavsar, DeGaulle I. Chigbu et al. · Antioxidants Open access 5 Feb 2019 598
24 Flavonoids as prospective compounds for anti-cancer therapy Divyashree Ravishankar, Amit Kumar Rajora, Francesca Greco et al. · The International Journal of Biochemistry & Cell Biology 12 Oct 2013 579
25 Effects of Flavonoids and other Polyphenols on Inflammation Raquel Muñoz-González, Isabel Ballester, Rocío López-Posadas et al. · Critical Reviews in Food Science and Nutrition 24 Mar 2011 577
26 Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages Yu‐Chih Liang, Ying-Tang Huang, Shu-Huei Tsai et al. · Carcinogenesis Oct 1999 572
27 AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept Angelika Bierhaus · Cardiovascular Research Mar 1998 557
28 Flavonoids in Health and Disease Robert B. Rucker · American Journal of Clinical Nutrition Open access May 2004 555
29 Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders Biswanath Dinda, Subhajit Dinda, Saikat DasSharma et al. · European Journal of Medicinal Chemistry Open access 6 Mar 2017 555
30 Anti-Oxidant, Anti-Inflammatory and Anti-Allergic Activities of Luteolin Günter Seelinger, Irmgard Merfort, Christoph Mathis Schempp · Planta Medica Open access 20 Oct 2008 555
31 Flavonoids: A versatile source of anticancer drugs Neelu Sharma, MahabeerP Dobhal, YogeshC Joshi et al. · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review Open access 2011 553
32 Scutellaria baicalensis , the golden herb from the garden of Chinese medicinal plants Qing Jie Zhao, Xiao‐Ya Chen, Cathie R. Martin · 中国科学通报:英文版 Open access 8 Jul 2016 551
33 Apigenin in cancer therapy: anti-cancer effects and mechanisms of action Xiaohui Yan, Qi Miao, Pengfei Li et al. · Cell & Bioscience Open access 5 Oct 2017 549
34 Flavones: An important scaffold for medicinal chemistry Manjinder Singh, Maninder Kaur, Om Silakari · European Journal of Medicinal Chemistry Open access 5 Jul 2014 543
35 Antioxidant properties in vitro and total phenolic contents in methanol extracts from medicinal plants Hua‐Bin Li, Chi-Chun Wong, Ka‐Wing Cheng et al. · LWT 27 Mar 2007 542
36 Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition Georgine Agullo, Laurence Gamet‐Payrastre, Stéphane Manenti et al. · Biochemical Pharmacology Jun 1997 539
37 Apigenin and cancer chemoprevention: Progress, potential and promise (Review) Deendayal Patel, Sanjeev Shukla, Sanjay Gupta · International Journal of Oncology Open access 2007 527
38 Fisetin: A Dietary Antioxidant for Health Promotion Naghma Khan, Deeba N. Syed, Nihal Ahmad et al. · Antioxidants and Redox Signaling Open access 2 Nov 2012 516
39 An Update Review of Saffron and its Active Constituents José Luis Rı́os, M. Carmen Recio, Rosa María Giner et al. · Phytotherapy Research May 1996 500
40 Several Culinary and Medicinal Herbs Are Important Sources of Dietary Antioxidants Steinar Dragland, Haruki Senoo, Kenjiro Wake et al. · Journal of Nutrition Open access May 2003 497
41 Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations Jun Tang, Yibin Feng, Sai‐Wah Tsao et al. · Journal of Ethnopharmacology Open access 16 Aug 2009 490
42 The Flavonoid Baicalein Inhibits Fibrillation of α-Synuclein and Disaggregates Existing Fibrils Min Zhu, Sudha Rajamani, Joanna J. Kaylor et al. · Journal of Biological Chemistry Open access Jun 2004 488
43 Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines Sabine Kuntz, Uwe Wenzel, Hannelore Daniel · European Journal of Nutrition 9 Jul 1999 486
44 A review on the pharmacological effects of vitexin and isovitexin Miao He, Jia‐Wei Min, Weilin Kong et al. · Fitoterapia 30 Sep 2016 485
45 Scutellaria baicalensis Georgi. (Lamiaceae): a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology Tian-Tian Zhao, Hailong Tang, Long Xie et al. · Journal of Pharmacy and Pharmacology 25 Jun 2019 480
46 Flavonols and Flavones as Potential anti‐Inflammatory, Antioxidant, and Antibacterial Compounds Maria do Socorro S. Chagas, Maria Dutra Behrens, Carla Junqueira Moragas-Tellis et al. · Oxidative Medicine and Cellular Longevity Open access 2022 475
47 Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action Renuka Mani, Vijayakumar Natesan · Phytochemistry 21 Nov 2017 464
48 Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients Hai-xia Su et al. · Acta Pharmacologica Sinica Open access 31 Jul 2020 462
49 Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review Ricardo Costa, Hyo Sook Han, William John Gradishar · Breast Cancer Research and Treatment 7 Feb 2018 461
50 Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells Ing‐Kae Wang, Shoei‐Yn Lin‐Shiau, Jinxi Lin · European Journal of Cancer Oct 1999 460

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.