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Most cited papers in Head and Neck Cancer Studies

What are the most cited papers in Head and Neck Cancer Studies?

The most cited paper in Head and Neck Cancer Studies is "Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer" (K. Kian Ang, Jonathan Harris, Richard H. Wheeler et al., 2010), with 6,617 citations. Next come "Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer" (6,330) and "Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck" (5,189).

Showing 50 of 100 papers. Every paper with more than 1,113 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer K. Kian Ang, Jonathan Harris, Richard H. Wheeler et al. · New England Journal of Medicine Open access 7 Jun 2010 6,617
2 Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer Núbia Muñóz, Francesc Xavier Bosch, Sílvia de Sanjosé et al. · New England Journal of Medicine Open access 5 Feb 2003 6,330
3 Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck Robert Louis Ferris et al. · New England Journal of Medicine Open access 9 Oct 2016 5,189
4 Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck James A. Bonner, Paul M. Harari, J. Giralt et al. · New England Journal of Medicine Open access 8 Feb 2006 5,137
5 Head and neck squamous cell carcinoma Daniel E. Johnson, Barbara Ann Burtness, Charles René Leemans et al. · Nature Reviews Disease Primers ReviewOpen access 26 Nov 2020 4,223
6 Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer Jan B. Vermorken, Ricard Mesı́a, Fernando Rivera et al. · New England Journal of Medicine Open access 10 Sep 2008 3,762
7 Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States Anil K. Chaturvedi, Eric A. Engels, Ruth M. Pfeiffer et al. · Journal of Clinical Oncology Open access 4 Oct 2011 3,651
8 Global epidemiology of oral and oropharyngeal cancer Saman Warnakulasuriya · Oral Oncology 19 Sep 2008 3,484
9 Prevalence of Human Papillomavirus in Cervical Cancer: a Worldwide Perspective Francesc Xavier Bosch, M. Michele Manos, N. Munoz et al. · JNCI Journal of the National Cancer Institute 7 Jun 1995 3,439
10 Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study Barbara Ann Burtness et al. · The Lancet Open access219 authors Nov 2019 3,344
11 Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck Jay Scott Cooper, Thomas F. Pajak, Arlene A. Forastiere et al. · New England Journal of Medicine 5 May 2004 3,297
12 Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer Jacques Bernier, Christian Domenge, Mahmut Özsahin et al. · New England Journal of Medicine Open access 5 May 2004 3,214
13 Concurrent Chemotherapy and Radiotherapy for Organ Preservation in Advanced Laryngeal Cancer Arlene A. Forastiere, Helmuth Goepfert, Moshe H Maor et al. · New England Journal of Medicine Open access 26 Nov 2003 3,192
14 Nasopharyngeal carcinoma Yu‐Pei Chen, Anthony T.�C. Chan, Quynh‐Thu Le et al. · The Lancet 7 Jun 2019 3,186
15 Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers Maura L. Gillison · JNCI Journal of the National Cancer Institute 3 May 2000 3,121
16 Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients Jean‐Pierre Pignon, Aurélie Le Maître, E. Maillard et al. · Radiotherapy and Oncology Review 15 May 2009 3,081
17 Improved Survival of Patients With Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma in a Prospective Clinical Trial Carole Fakhry, William H. Westra, S. Li et al. · JNCI Journal of the National Cancer Institute 12 Feb 2008 2,814
18 Case–Control Study of Human Papillomavirus and Oropharyngeal Cancer Gypsyamber DʼSouza, Aimée R. Kreimer, Raphael P. Viscidi et al. · New England Journal of Medicine 9 May 2007 2,706
19 Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial Joël Shapiro et al. · The Lancet Oncology 6 Aug 2015 2,615
20 The molecular biology of head and neck cancer Charles René Leemans, Boudewijn J.M. Braakhuis, Ruud H. Brakenhoff · Nature reviews. Cancer Review 16 Dec 2010 2,566
21 Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data Jean‐Pierre Pignon, Jean Bourhis, Christian Domenge et al. · The Lancet Mar 2000 2,479
22 Autologous Bone Marrow Transplantation as Compared with Salvage Chemotherapy in Relapses of Chemotherapy-Sensitive Non-Hodgkin's Lymphoma Thierry O. Philip, Cesare Guglielmi, Anton Hagenbeek et al. · New England Journal of Medicine 7 Dec 1995 2,458
23 Worldwide burden of cancer attributable to HPV by site, country and HPV type Catherine de Martel, Martyn Plummer, Jérôme Vignat et al. · International Journal of Cancer Open access 4 Apr 2017 2,393
24 Capecitabine and Oxaliplatin for Advanced Esophagogastric Cancer David Cunningham, Naureen Starling, Sheela Rao et al. · New England Journal of Medicine 2 Jan 2008 2,326
25 Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099. Muhyi Al‐Sarraf, Michael Leo LeBlanc, Padmini Giri et al. · Journal of Clinical Oncology Apr 1998 2,245
26 Head and neck cancer Athanassios E. Argiris, Michalis V. Karamouzis, David Raben et al. · The Lancet Open access May 2008 2,240
27 Head and Neck Cancer Everett E. Vokes, Ralph R. Weichselbaum, Scott Michael Lippman et al. · New England Journal of Medicine 21 Jan 1993 2,223
28 Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review Aimée R. Kreimer, Gary M. Clifford, Peter A. Boyle et al. · Cancer Epidemiology Biomarkers & Prevention Review Feb 2005 2,191
29 Head and Neck Cancer Laura Q.M. Chow · New England Journal of Medicine 2020 2,145
30 Smoking and drinking in relation to oral and pharyngeal cancer. William J. Blot, Joseph K. McLaughlin, Deborah M. Winn et al. · PubMed Jun 1988 2,020
31 Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival James A. Bonner, Paul M. Harari, J. Giralt et al. · The Lancet Oncology 12 Nov 2009 1,984
32 Chemoradiotherapy of Locally Advanced Esophageal Cancer Jay Scott Cooper, Matthew D. Guo, Arnold M. Herskovic et al. · JAMA 5 May 1999 1,982
33 A Comparison of Multimodal Therapy and Surgery for Esophageal Adenocarcinoma T. N. Walsh, N. Noonan, Donal P. Hollywood et al. · New England Journal of Medicine Open access 15 Aug 1996 1,961
34 Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials Guglielmo Ronco, Joakim Dillner, K. Miriam Elfström et al. · The Lancet Open access 2 Nov 2013 1,845
35 HPV-associated head and neck cancer: a virus-related cancer epidemic Shanthi Marur, Gypsyamber DʼSouza, William H. Westra et al. · The Lancet Oncology Open access 6 May 2010 1,839
36 Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501) Jacques Bernier, Jay Scott Cooper, Thomas F. Pajak et al. · Head & Neck 2005 1,782
37 Nomenclature and classification of potentially malignant disorders of the oral mucosa Saman Warnakulasuriya, Newell Walter Johnson, Isaäc van der Waal · Journal of Oral Pathology and Medicine Open access 26 Jul 2007 1,775
38 Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial Tanguy Y. Seiwert, Barbara Ann Burtness, Ranee Mehra et al. · The Lancet Oncology 28 May 2016 1,766
39 An Intergroup Phase III Comparison of Standard Radiation Therapy and Two Schedules of Concurrent Chemoradiotherapy in Patients With Unresectable Squamous Cell Head and Neck Cancer David J. Adelstein, Yi Li, George L. Adams et al. · Journal of Clinical Oncology 28 Dec 2002 1,759
40 Mortality due to cancer treatment delay: systematic review and meta-analysis Timothy Paul Hanna, Will D. King, Stéphane Thibodeau et al. · BMJ ReviewOpen access 4 Nov 2020 1,749
41 A Prognostic Score for Advanced Hodgkin's Disease Dirk Hasenclever et al. · New England Journal of Medicine Open access 19 Nov 1998 1,749
42 Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study Ezra E.W. Cohen et al. · The Lancet Open access113 authors 30 Nov 2018 1,731
43 Cisplatin, Fluorouracil, and Docetaxel in Unresectable Head and Neck Cancer Jan Baptist Vermorken, Éva Remenár, Carla van Herpen et al. · New England Journal of Medicine Open access 24 Oct 2007 1,726
44 Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial Christopher M. Nutting, James P. Morden, Kevin Joseph Harrington et al. · The Lancet Oncology Open access 14 Jan 2011 1,721
45 Cisplatin and Fluorouracil Alone or with Docetaxel in Head and Neck Cancer Marshall R. Posner et al. · New England Journal of Medicine Open access 24 Oct 2007 1,713
46 Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer Fabio Landoni, Andrea Maneo, Alessandro Colombo et al. · The Lancet Aug 1997 1,704
47 Head and neck cancers—major changes in the American Joint Committee on cancer eighth edition cancer staging manual William M. Lydiatt, Snehal G. Patel, Brian P O'Sullivan et al. · CA A Cancer Journal for Clinicians Open access 27 Jan 2017 1,687
48 Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis Katrin Marie Sjoquist, Bryan Henry Burmeister, Bernard Mark Smithers et al. · The Lancet Oncology 21 Jun 2011 1,669
49 Cervical Human Papillomavirus Prevalence in 5 Continents: Meta‐Analysis of 1 Million Women with Normal Cytological Findings Laia Bruni, Mireia Díaz, Xavier Castellsagué et al. · The Journal of Infectious Diseases 10 Nov 2010 1,666
50 Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women Jorma A. Paavonen et al. · The Lancet Jul 2009 1,663

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.