Most cited papers in Healthcare and Venom Research
What are the most cited papers in Healthcare and Venom Research?
The most cited paper in Healthcare and Venom Research is "Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs" (C. A. Winter, Edwin A. Risley, George W. Nuss, 1962), with 5,701 citations. Next come "Neuronal Plasticity: Increasing the Gain in Pain" (3,780) and "An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat" (3,067).
Showing 50 of 100 papers. Every paper with more than 354 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs C. A. Winter, Edwin A. Risley, George W. Nuss · Experimental Biology and Medicine | Dec 1962 | 5,701 |
| 2 | Neuronal Plasticity: Increasing the Gain in Pain Clifford J. Woolf, Michael W. Salter · Science | 9 Jun 2000 | 3,780 |
| 3 | An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat Sun Ho Kim, Jin Mo Chung · Pain | Sep 1992 | 3,067 |
| 4 | The Global Burden of Snakebite: A Literature Analysis and Modelling Based on Regional Estimates of Envenoming and Deaths Anuradhani Kasturiratne, A. Rajitha Wickremasinghe, Nilanthi de Silva et al. · PLoS Medicine | 31 Oct 2008 | 1,950 |
| 5 | Bee and Wasp Venoms Ernst Habermann · Science | 28 Jul 1972 | 1,571 |
| 6 | Sequence and specificity of two antibacterial proteins involved in insect immunity H. Steiner, Dan Hultmark, Åke Engström et al. · Nature | Jul 1981 | 1,444 |
| 7 | Colony Collapse Disorder: A Descriptive Study Dennis vanEngelsdorp, Jay Daniel Evans, Claude Saegerman et al. · PLoS ONE | 31 Jul 2009 | 1,368 |
| 8 | Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1β, Interleukin-6, and Tumor Necrosis Factor-α in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord Yasuhiko Kawasaki, Ling Zhang, Jen‐Kun Cheng et al. · Journal of Neuroscience | 14 May 2008 | 1,164 |
| 9 | Structure−Activity Relationship and Classification of Flavonoids as Inhibitors of Xanthine Oxidase and Superoxide Scavengers Paul Cos, Ying Li, Mario R. Calomme et al. · Journal of Natural Products | 1998 | 1,088 |
| 10 | Role of interleukin 10 in specific immunotherapy. Cezmi A. Akdiş, Thorsten Blesken, Mübeccel Akdiş et al. · Journal of Clinical Investigation | Jul 1998 | 975 |
| 11 | Propolis: Is there a potential for the development of new drugs? José Maurício Sforcin, Vassya Stefanova Bankova · Journal of Ethnopharmacology | 22 Oct 2010 | 882 |
| 12 | Specific Inhibition of Nuclear RNA Polymerase II by α-Amanitin Thomas J. Lindell, Fanyela Weinberg, Paul W. Morris et al. · Science | 23 Oct 1970 | 872 |
| 13 | Neurologic Complications of the Reactivation of Varicella–Zoster Virus Donald H. Gilden, Bette Kay Kleinschmidt-DeMasters, James J. LaGuardia et al. · New England Journal of Medicine | 2 Mar 2000 | 856 |
| 14 | The Antibacterial Activity of Honey Peter C. Molan · Bee World | 1992 | 826 |
| 15 | Glutamate neurotoxicity in cortical cell culture is calcium dependent Dennis W. Choi · Neuroscience Letters | Aug 1985 | 818 |
| 16 | Ethanolic Extract of Propolis (EEP) Enhances the Apoptosis- Inducing Potential of TRAIL in Cancer Cells Ewelina Szliszka, Zenon Paweł Czuba, Maciej Domino et al. · Molecules | 13 Feb 2009 | 815 |
| 17 | Innate and conditioned reactions to threat in rats with amygdaloid lesions. D. Caroline Blanchard, Robert J. Blanchard · Journal of Comparative and Physiological Psychology | 1972 | 758 |
| 18 | Snake venom variability: methods of study, results and interpretation Jean‐Philippe Chippaux, Vaughan K. Williams, Jennifer A. White · Toxicon | 1991 | 756 |
| 19 | Varieties of Calcium-Activated Potassium Channels Ramón Latorre, Andrés F. Oberhauser, Pedro P. Labarca et al. · Annual Review of Physiology | Mar 1989 | 741 |
| 20 | Phenolic Compounds in Honey and Their Associated Health Benefits: A Review Danila Cianciosi, Tamara Yuliett Forbes-Hernández, Sadia Afrin et al. · Molecules | 11 Sep 2018 | 733 |
| 21 | Excitement ahead: structure, function and mechanism of snake venom phospholipase A2 enzymes R. Manjunatha Kini · Toxicon | Dec 2003 | 719 |
| 22 | Interfacial Catalysis: the Mechanism of Phospholipase A 2 David Lloyd Scott, Steven P. White, Zbyszek Otwinowski et al. · Science | 14 Dec 1990 | 706 |
| 23 | The evaluation of morphological characteristics of human spermatozoa according to stricter criteria Roelof Menkveld, Frik S.H. Stander, Theunis J. V. W. Kotze et al. · Human Reproduction | Jul 1990 | 685 |
| 24 | Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). Tsutomu Higashijima, Sonoko Uzu, Terumi Nakajima et al. · Journal of Biological Chemistry | May 1988 | 680 |
| 25 | Heritability of nociception I: Responses of 11 inbred mouse strains on 12 measures of nociception Jeffrey S. Mogil, Sonya G. Wilson, Karine Bon et al. · Pain | Mar 1999 | 658 |
| 26 | Melittin: a Membrane-active Peptide with Diverse Functions Hariharasundaram Raghuraman, Amitabha Chattopadhyay · Bioscience Reports | 30 Nov 2006 | 656 |
| 27 | Postherpetic Neuralgia — Pathogenesis, Treatment, and Prevention Rhonda G. Kost, Stephen E. Straus · New England Journal of Medicine | 4 Jul 1996 | 650 |
| 28 | Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds Dain Son, Jang‐Hern Lee, Yong Sun Lee et al. · Pharmacology & Therapeutics | 9 May 2007 | 633 |
| 29 | Snake Envenoming: A Disease of Poverty Robert A. Harrison, Adam D Hargreaves, Simon C. Wagstaff et al. · PLoS neglected tropical diseases | 21 Dec 2009 | 624 |
| 30 | Structure and Functions of Channel-Forming Peptides: Magainins, Cecropins, Melittin and Alamethicin Burkhard Bechinger · The Journal of Membrane Biology | Apr 1997 | 605 |
| 31 | The retrograde axonal transport of nerve growth factor Ian A. Hendry, K. Sto ̈ckel, H. Thoenen et al. · Brain Research | Mar 1974 | 602 |
| 32 | STUDIES ON THE QUANTITATIVE METHOD FOR DETERMINATION OF HEMORRHAGIC ACTIVITY OF HABU SNAKE VENOM Hisashi Kondo, Satoru Kondo, HIROO IKEZAWA et al. · Japanese Journal of Medical Science and Biology | 1960 | 588 |
| 33 | Single apamin-blocked Ca-activated K+ channels of small conductance in cultured rat skeletal muscle Andrew L. Blatz, Karl L. Magleby · Nature | Oct 1986 | 562 |
| 34 | Diagnosis of Hymenoptera venom allergy Beatrice M Bilò, Franziska Ruëff, Holger Mosbech et al. · Allergy | 3 Oct 2005 | 557 |
| 35 | The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways Takao Kataoka, Ralph C. Budd, Nils Holler et al. · Current Biology | Jun 2000 | 554 |
| 36 | Phospholipase A2 myotoxins from Bothrops snake venoms José Marı́a Gutiérrez, Bruno Lomonte · Toxicon | Nov 1995 | 536 |
| 37 | A Peptide c-Jun N-Terminal Kinase (JNK) Inhibitor Blocks Mechanical Allodynia after Spinal Nerve Ligation: Respective Roles of JNK Activation in Primary Sensory Neurons and Spinal Astrocytes for Neuropathic Pain Development and Maintenance Zhi‐Ye Zhuang, Yeong‐Ray Wen, De-Ren Zhang et al. · Journal of Neuroscience | 29 Mar 2006 | 535 |
| 38 | Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy James N. Francis, Stephen J. Till, Stephen R. Durham · Journal of Allergy and Clinical Immunology | Jun 2003 | 530 |
| 39 | Lidocaine patch: double-blind controlled study of a new treatment method for post-herpetic neuralgia Michael C. Rowbotham, Pamela Stitzlein Davies, Christina Verkempinck et al. · Pain | Apr 1996 | 529 |
| 40 | On the role of Hsp27 in regulating apoptosis Caoimhín G. Concannon, Adrienne M. Gorman, Afshin Samali · APOPTOSIS | 2003 | 526 |
| 41 | Venoms as a platform for human drugs: translating toxins into therapeutics Glenn F. King · Expert Opinion on Biological Therapy | 23 Sep 2011 | 524 |
| 42 | Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures. Marek Jutel, Werner J. Pichler, D Skrbic et al. · The Journal of Immunology | Apr 1995 | 524 |
| 43 | Honey as a topical treatment for wounds Andrew Jull, Nicky A Cullum, Jo C Dumville et al. · Cochrane Database of Systematic Reviews | 6 Mar 2015 | 523 |
| 44 | Tumor Necrosis Factor-α Induces Mechanical Allodynia after Spinal Nerve Ligation by Activation of p38 MAPK in Primary Sensory Neurons Maria Schäfers, Camilla I. Svensson, Claudia Sommer et al. · Journal of Neuroscience | Apr 2003 | 523 |
| 45 | On the influence of mechanical surface treatments—deep rolling and laser shock peening—on the fatigue behavior of Ti–6Al–4V at ambient and elevated temperatures Ravi K. Nalla, Igor Altenberger, Ulf Noster et al. · Materials Science and Engineering A | 30 Apr 2003 | 519 |
| 46 | Lumbar Disc Degeneration Michele Crites Battié, Tapio Videman, Éric Parent · Spine | 24 Nov 2004 | 510 |
| 47 | Antioxidant Potential of Propolis, Bee Pollen, and Royal Jelly: Possible Medical Application Joanna Kocot, Małgorzata Kiełczykowska, Dorota Luchowska-Kocot et al. · Oxidative Medicine and Cellular Longevity | 2018 | 504 |
| 48 | A pharmacological study of the depression of spinal neurones by glycine and related amino acids D.R. Curtis, L. H�sli, Graham A.R. Johnston · Experimental Brain Research | Jul 1968 | 504 |
| 49 | The structure of melittin. II. Interpretation of the structure. Thomas C. Terwilliger, David S Eisenberg · Journal of Biological Chemistry | Jun 1982 | 504 |
| 50 | Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain Huasheng Xiao, Qiuhua Huang, Fang‐Xiong Zhang et al. · Proceedings of the National Academy of Sciences | 11 Jun 2002 | 503 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.