Most cited papers in Heavy Metal Exposure and Toxicity
What are the most cited papers in Heavy Metal Exposure and Toxicity?
The most cited paper in Heavy Metal Exposure and Toxicity is "An Association between Air Pollution and Mortality in Six U.S. Cities" (Douglas W. Dockery, C. Arden Pope, Xiping Xu et al., 1993), with 8,197 citations. Next come "Selenium: Biochemical Role as a Component of Glutathione Peroxidase" (7,831) and "Heavy Metal Toxicity and the Environment" (7,216).
Showing 50 of 100 papers. Every paper with more than 1,168 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | An Association between Air Pollution and Mortality in Six U.S. Cities Douglas W. Dockery, C. Arden Pope, Xiping Xu et al. · New England Journal of Medicine | 9 Dec 1993 | 8,197 |
| 2 | Selenium: Biochemical Role as a Component of Glutathione Peroxidase John T. Rotruck, Alun Lloyd Pope, Howard E. Ganther et al. · Science | 9 Feb 1973 | 7,831 |
| 3 | Heavy Metal Toxicity and the Environment Paul B. Tchounwou, Clément G. Yedjou, Anita K. Patlolla et al. · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions | 2012 | 7,216 |
| 4 | Hazards of heavy metal contamination Lars Järup · British Medical Bulletin | Dec 2003 | 6,521 |
| 5 | Toxicity, mechanism and health effects of some heavy metals Monisha Jaishankar, Tenzin Tseten, Naresh Anbalagan et al. · Interdisciplinary Toxicology | Jun 2014 | 6,413 |
| 6 | Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling Xia Chen, Min Xiu, Juanjuan Xing et al. · Cellular Physiology and Biochemistry | 2017 | 5,752 |
| 7 | Heavy metal pollution in the environment and their toxicological effects on humans Jessica F. Briffa, Emmanuel Sinagra, Renald A. Blundell · Heliyon | Sep 2020 | 4,377 |
| 8 | The importance of selenium to human health Margaret P. Rayman · The Lancet | Jul 2000 | 4,171 |
| 9 | Arsenic round the world: a review Badal Kumar Mandal, Kazuo T Suzuki · Talanta | Aug 2002 | 3,559 |
| 10 | Arsenic removal from water/wastewater using adsorbents—A critical review Dinesh Mohan, Charles U. Pittman · Journal of Hazardous Materials | 8 Jan 2007 | 3,544 |
| 11 | Selenium and human health Margaret P. Rayman · The Lancet | 28 Feb 2012 | 3,542 |
| 12 | Glutathione peroxidase activity in selenium-deficient rat liver Richard A Lawrence, Raymond F. Burk · Biochemical and Biophysical Research Communications | Aug 1976 | 3,541 |
| 13 | Advances in metal-induced oxidative stress and human disease Klaudia Jomová, Marián Valko · Toxicology | 16 Mar 2011 | 3,223 |
| 14 | Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation Hazrat Ali, Ezzat Khan, Ikram Ilahi · Journal of Chemistry | 5 Mar 2019 | 3,207 |
| 15 | Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic Mahdi Balali‐Mood, Kobra Naseri, Zoya Tahergorabi et al. · Frontiers in Pharmacology | 13 Apr 2021 | 3,112 |
| 16 | A review of soil heavy metal pollution from mines in China: Pollution and health risk assessment Zhiyuan Li, Zongwei Ma, Tsering Jan van der Kuijp et al. · The Science of The Total Environment | 25 Sep 2013 | 2,880 |
| 17 | Antimicrobial activity of metals: mechanisms, molecular targets and applications Joseph A. Lemire, Joe Jonathan Harrison, Raymond Joseph Turner · Nature Reviews Microbiology | 13 May 2013 | 2,763 |
| 18 | The Effects of Cadmium Toxicity Giuseppe Genchi, Maria Stefania Sinicropi, Graziantonio Lauria et al. · International Journal of Environmental Research and Public Health | 26 May 2020 | 2,707 |
| 19 | Mercury as a Global Pollutant: Sources, Pathways, and Effects Charles T. Driscoll, Robert P. Mason, Hing Man Chan et al. · Environmental Science & Technology | 16 Apr 2013 | 2,551 |
| 20 | Health risks of heavy metals in contaminated soils and food crops irrigated with wastewater in Beijing, China Shakeel A. Khan, Qing L. Cao, Yi Zheng et al. · Environmental Pollution | 28 Aug 2007 | 2,384 |
| 21 | The Toxicology of Mercury and Its Chemical Compounds Thomas William Clarkson, Laszlo Magos · Critical Reviews in Toxicology | 2006 | 2,382 |
| 22 | Current status of cadmium as an environmental health problem Lars Järup, Agneta Åkesson · Toxicology and Applied Pharmacology | 5 May 2009 | 2,370 |
| 23 | Low-Level Environmental Lead Exposure and Children’s Intellectual Function: An International Pooled Analysis Bruce Perrin Lanphear, Richard Hornung, Jane C. Khoury et al. · Environmental Health Perspectives | 18 Mar 2005 | 2,207 |
| 24 | Copper toxicity, oxidative stress, and antioxidant nutrients Lisa M. Gaetke · Toxicology | 2 Jun 2003 | 2,176 |
| 25 | Toxicity of lead: a review with recent updates Gagan D. Flora, Deepesh Gupta, Archana Tiwari · Interdisciplinary Toxicology | 9 Nov 2012 | 2,172 |
| 26 | Copper, iron and zinc in Alzheimer's disease senile plaques Mark A. Lovell, J. David Robertson, William J. Teesdale et al. · Journal of the Neurological Sciences | Jun 1998 | 2,128 |
| 27 | Intellectual Impairment in Children with Blood Lead Concentrations below 10 μg per Deciliter Richard L. Canfield, Charles Henderson, Deborah A. Cory‐Slechta et al. · New England Journal of Medicine | 16 Apr 2003 | 2,089 |
| 28 | Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging Emily L. Que, Dylan Wythe Domaille, Christopher J. Chang · Chemical Reviews | 22 Apr 2008 | 2,072 |
| 29 | Impact of heavy metals on the environment and human health: Novel therapeutic insights to counter the toxicity Saikat Mitra, Arka Jyoti Chakraborty, Abu Montakim Tareq et al. · Journal of King Saud University - Science | 29 Jan 2022 | 2,058 |
| 30 | Heavy metals in food crops: Health risks, fate, mechanisms, and management Prabhat Kumar, Sang Soo Lee, Ming Zhang et al. · Environment International | 9 Feb 2019 | 2,050 |
| 31 | Remediation of heavy metal(loid)s contaminated soils – To mobilize or to immobilize? Nanthi Sirangie Bolan, Anitha Kunhikrishnan, Ramya Thangarajan et al. · Journal of Hazardous Materials | 21 Dec 2013 | 2,035 |
| 32 | In vitro toxicity of nanoparticles in BRL 3A rat liver cells Saber M. Hussain, K.L. Hess, Jeffery M. Gearhart et al. · Toxicology in Vitro | 26 Aug 2005 | 2,031 |
| 33 | Contamination of drinking-water by arsenic in Bangladesh: a public health emergency. A H Smith, Elena O. Lingas, Mizanur Rahman · PubMed | 2000 | 1,993 |
| 34 | Developmental neurotoxicity of industrial chemicals Philippe Grandjean, PJ Landrigan · The Lancet | 14 Nov 2006 | 1,978 |
| 35 | The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene Peter C. Bull, Gordon R. Thomas, Johanna M. Rommens et al. · Nature Genetics | Dec 1993 | 1,966 |
| 36 | Urinary Creatinine Concentrations in the U.S. Population: Implications for Urinary Biologic Monitoring Measurements Dana Boyd Barr, Lynn C. Wilder, Samuel P. Caudill et al. · Environmental Health Perspectives | 23 Sep 2004 | 1,960 |
| 37 | Toxic Metals and Oxidative Stress Part I: Mechanisms Involved in Me-tal induced Oxidative Damage Bentham Science Publisher Nuran Ercal, Bentham Science Publisher Hande Gurer-Orhan, Bentham Science Publisher Nukhet Aykin-Burns · Current Topics in Medicinal Chemistry | Dec 2001 | 1,949 |
| 38 | Lead toxicity: a review Ab Latif Wani, Anjum Ara, Jawed Ahmad Usmani · Interdisciplinary Toxicology | Jun 2015 | 1,945 |
| 39 | Environmental Health Perspectives TJ Goehl · Environmental Health Perspectives | Apr 2002 | 1,943 |
| 40 | Bed sediment-associated trace metals in an urban stream, Oahu, Hawaii Ross A. Sutherland · Environmental Geology | 18 Apr 2000 | 1,917 |
| 41 | The neurobiology of zinc in health and disease Christopher J. Frederickson, Jae‐Young Koh, Ashley Ian Bush · Nature reviews. Neuroscience | 13 May 2005 | 1,864 |
| 42 | Ecological effects, transport, and fate of mercury: a general review Dean W. Boening · Chemosphere | Jun 2000 | 1,852 |
| 43 | The Toxicology of Mercury — Current Exposures and Clinical Manifestations Thomas William Clarkson, Laszlo Magos, GARY JAY MYERS · New England Journal of Medicine | 29 Oct 2003 | 1,772 |
| 44 | Cognitive Deficit in 7-Year-Old Children with Prenatal Exposure to Methylmercury Philippe Grandjean, Pál Weihe, Roberta F. White et al. · Neurotoxicology and Teratology | Nov 1997 | 1,744 |
| 45 | Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity Amruta Manke, Liying Wang, Yon Rojanasakul · BioMed Research International | 2013 | 1,737 |
| 46 | Arsenic toxicity and potential mechanisms of action Michael F. Hughes · Toxicology Letters | Jul 2002 | 1,670 |
| 47 | THE CHEMICAL CYCLE AND BIOACCUMULATION OF MERCURY François M. M. Morel, Anne M. L. Kraepiel, Marc Amyot · Annual Review of Ecology and Systematics | Nov 1998 | 1,638 |
| 48 | Mechanisms for copper acquisition, distribution and regulation Byung‐Eun Kim, Tracy Nevitt, Dennis J. Thiele · Nature Chemical Biology | 15 Feb 2008 | 1,620 |
| 49 | Zinc and immune function: the biological basis of altered resistance to infection Anuraj H. Shankar, Ananda Shiva Prasad · American Journal of Clinical Nutrition | Aug 1998 | 1,613 |
| 50 | Prevalence of exposure of heavy metals and their impact on health consequences Kanwal Rehman, Fiza Fatima, Iqra Waheed et al. · Journal of Cellular Biochemistry | 23 Jun 2017 | 1,600 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.