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Most cited papers in Hepatitis B Virus Studies

What are the most cited papers in Hepatitis B Virus Studies?

The most cited paper in Hepatitis B Virus Studies is "Human papillomavirus is a necessary cause of invasive cervical cancer worldwide" (Jan M.M. Walboomers, Marcel V. Jacobs, M. Michele Manos et al., 1999), with 9,115 citations. Next come "Management of Hepatocellular Carcinoma: An Update Δσ" (8,176) and "Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome" (6,911).

Showing 50 of 99 papers. Every paper with more than 1,353 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Human papillomavirus is a necessary cause of invasive cervical cancer worldwide Jan M.M. Walboomers, Marcel V. Jacobs, M. Michele Manos et al. · The Journal of Pathology Open access Sep 1999 9,115
2 Management of Hepatocellular Carcinoma: An Update Δσ Jordi Bruix, Morris Sherman · Hepatology Open access 19 Jan 2011 8,176
3 Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome Qui‐Lim Choo, George C. Kuo, Amy J. Weiner et al. · Science 21 Apr 1989 6,911
4 Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial Michael Peter Manns, John G. McHutchison, Stuart C. Gordon et al. · The Lancet Sep 2001 6,056
5 Management of Hepatocellular Carcinoma * Jordi Bruix, Morris Sherman · Hepatology Open access 26 Oct 2005 5,904
6 Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial Ann‐Lii Cheng et al. · The Lancet Oncology 18 Dec 2008 5,881
7 Hepatocellular carcinoma Alejandro Forner, María Reig, Jordi Bruix · The Lancet 4 Jan 2018 5,713
8 EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection Pietro Lampertico, Kosh Agarwal, Thomas Berg et al. · Journal of Hepatology 18 Apr 2017 5,528
9 Acute Abdomen: A Rare Case of Ruptured Hepatocellular Carcinoma Severin Gloor, Kai Oliver Jensen, Stefan Breitenstein et al. · Case Reports in Gastroenterology Open access 21 Mar 2017 5,376
10 The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets Gisa Gerold, Thomas Pietschmann · Digestive Diseases Open access 2014 4,864
11 Liver fibrosis Ramon A. Bataller, David A. Brenner · Journal of Clinical Investigation Open access Feb 2005 4,815
12 Hepatocellular Carcinoma Augusto García Villanueva · New England Journal of Medicine 10 Apr 2019 4,745
13 Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases Jorge A. Marrero, Laura Kulik, Claude B. Sirlin et al. · Hepatology Open access 6 Apr 2018 4,682
14 A Simple Noninvasive Index Can Predict Both Significant Fibrosis and Cirrhosis in Patients With Chronic Hepatitis C Chun‐Tao Wai, Joel K. Greenson, Robert J. Fontana et al. · Hepatology Open access 25 Jul 2003 4,422
15 Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance Norah A. Terrault, Anna S. Lok, Brian J. McMahon et al. · Hepatology Open access 5 Feb 2018 4,390
16 Clinical Management of Hepatocellular Carcinoma. Conclusions of the Barcelona-2000 EASL Conference Jordi Bruix, Morris Sherman, Josep Maria Llovet et al. · Journal of Hepatology Sep 2001 4,098
17 Papillomaviruses and cancer: from basic studies to clinical application Harald zur Hausen · Nature reviews. Cancer Review May 2002 4,062
18 Hepatocellular carcinoma Josep Maria Llovet, Andrew Kenneth Burroughs, Jordi Bruix · The Lancet Dec 2003 3,620
19 The causal relation between human papillomavirus and cervical cancer Francesc Xavier Bosch, Attila Tibor Lorincz, N Munoz et al. · Journal of Clinical Pathology Open access Apr 2002 3,609
20 Hepatocellular Carcinoma Hashem B. El‐Serag · New England Journal of Medicine 21 Sep 2011 3,545
21 Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma Hashem B. El‐Serag · Gastroenterology Open access 24 Apr 2012 3,459
22 Effect of pegylation on pharmaceuticals J. Milton Harris, Robert B. Chess · Nature Reviews Drug Discovery Review 28 Feb 2003 3,437
23 Risk of Hepatocellular Carcinoma Across a Biological Gradient of Serum Hepatitis B Virus DNA Level Chien‐Jen Chen · JAMA 3 Jan 2006 3,164
24 Chronic hepatitis B Anna S. Lok, Brian J. McMahon · Hepatology Open access 26 Jan 2007 3,096
25 Human papillomavirus and cervical cancer MARK H. SCHIFFMAN, Philip E. Castle, José Jerónimo et al. · The Lancet Sep 2007 3,039
26 Hepatitis C Virus Infection Georg Michael Lauer, Bruce D. Walker · New England Journal of Medicine 5 Jul 2001 2,985
27 Diagnosis, management, and treatment of hepatitis C: An update # † ‡ Marc G. Ghany, Doris B. Strader, David L. Thomas et al. · Hepatology Open access 2 Dec 2008 2,985
28 HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS R. Palmer Beasley, Chia‐Chin Lin, Lu‐Yu Hwang et al. · The Lancet Nov 1981 2,879
29 Rising Incidence of Hepatocellular Carcinoma in the United States Hashem B. El‐Serag, Andrew C. Mason · New England Journal of Medicine 11 Mar 1999 2,871
30 Chronic hepatitis B: Update 2009 # Anna S. Lok, Brian J. McMahon · Hepatology Open access 28 Jul 2009 2,851
31 Peginterferon-α2a and Ribavirin Combination Therapy in Chronic Hepatitis C Stephanos J. Hadziyannis, Hoel Sette, Timothy R. Morgan et al. · Annals of Internal Medicine 2 Mar 2004 2,842
32 Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line Volker Lohmann, Frank Körner, Jan Oliver Koch et al. · Science 2 Jul 1999 2,814
33 Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013 Aparna Schweitzer, Johannes Horn, Rafael Mikolajczyk et al. · The Lancet Review 28 Jul 2015 2,802
34 Global epidemiology of hepatitis C virus infection Colin W. Shepard, Lyn Finelli, Miriam J. Alter · The Lancet Infectious Diseases 25 Aug 2005 2,769
35 Production of infectious hepatitis C virus in tissue culture from a cloned viral genome Takaji Wakita, Thomas Pietschmann, Takanobu Kato et al. · Nature Medicine Open access 12 Jun 2005 2,753
36 Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures Daniel Lavanchy · Journal of Viral Hepatitis 20 Feb 2004 2,663
37 Hepatocellular carcinoma in cirrhosis: Incidence and risk factors Giovanna Fattovich, Tommaso Stroffolini, I. Zagni et al. · Gastroenterology Nov 2004 2,615
38 An inventory for assessing different kinds of hostility. Arnold H. Buss, Ann Durkee · Journal of Consulting Psychology 1957 2,615
39 Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update Shiv Kumar Sarin et al. · Hepatology International Open access 13 Nov 2015 2,603
40 The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide Joseph F. Perz, Gregory L. Armstrong, Leigh A. Farrington et al. · Journal of Hepatology Open access 24 Jun 2006 2,597
41 Hepatitis B Virus Infection William M. Lee · New England Journal of Medicine 11 Dec 1997 2,588
42 Classification of chronic hepatitis: Diagnosis, grading and staging Valeer J. Desmet, Michael A. Gerber, Jay H. Hoofnagle et al. · Hepatology Jun 1994 2,578
43 Primary liver cancer: Worldwide incidence and trends Francesc Xavier Bosch, Josepa Ribes, Mireia Díaz et al. · Gastroenterology Nov 2004 2,507
44 Hepatitis B Virus Infection — Natural History and Clinical Consequences Don Ganem, Alfred M. Prince · New England Journal of Medicine 10 Mar 2004 2,384
45 Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus Thierry Poynard, Patrick Marcellin, Samuel S. Lee et al. · The Lancet Oct 1998 2,335
46 Lamivudine for Patients with Chronic Hepatitis B and Advanced Liver Disease Yun‐Fan Liaw, Joseph J.�Y. Sung, Wan Cheng Chow et al. · New England Journal of Medicine Open access 6 Oct 2004 2,281
47 Complete Replication of Hepatitis C Virus in Cell Culture Brett D. Lindenbach, Matthew J. Evans, Andrew J. Syder et al. · Science 9 Jun 2005 2,244
48 Sampling Variability of Liver Fibrosis in Chronic Hepatitis C Pierre Bédossa, Delphine Dargère, Valérie Paradis · Hepatology 25 Nov 2003 2,234
49 Epidemiology of Hepatocellular Carcinoma Katherine A. McGlynn, Jessica L. Petrick, Hashem B. El‐Serag · Hepatology Open access 22 Apr 2020 2,217
50 Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update Masao Omata et al. · Hepatology International Open access 15 Jun 2017 2,208

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.