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Most cited papers in Herbal Medicine Research Studies

What are the most cited papers in Herbal Medicine Research Studies?

The most cited paper in Herbal Medicine Research Studies is "Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides" (Solomon P. Wasser, 2002), with 2,138 citations. Next come "TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents" (1,950) and "Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin" (1,834).

Showing 50 of 100 papers. Every paper with more than 404 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides Solomon P. Wasser · Applied Microbiology and Biotechnology Nov 2002 2,138
2 TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents Diana M. Bautista, S.E. Jordt, Tetsuro Nikai et al. · Cell Open access Mar 2006 1,950
3 Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin Michael Bandell, Gina M. Story, Sun Wook Hwang et al. · Neuron Open access Mar 2004 1,834
4 Medicinal plants in therapy Norman R. Farnsworth, Olayiwola Akerele, Audrey S. Bingel · Journal of Ethnopharmacology Open access May 1987 1,369
5 Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents) João Β. Calixto · Brazilian Journal of Medical and Biological Research Open access Feb 2000 1,291
6 Botanical polysaccharides: Macrophage immunomodulation and therapeutic potential Igor A. Schepetkin, Mark T. Quinn · International Immunopharmacology 11 Nov 2005 1,203
7 Circadian control of the immune system Christoph Scheiermann, Yuya Kunisaki, Paul S. Frenette · Nature reviews. Immunology ReviewOpen access 8 Feb 2013 1,145
8 Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines Lindsey J. Macpherson, Adrienne E. Dubin, Michael J. Evans et al. · Nature Open access 21 Jan 2007 1,125
9 Traditional medicinal plant use in Northern Peru: tracking two thousand years of healing culture Rainer Willi Bussmann, Douglas Sharon · Journal of Ethnobiology and Ethnomedicine Open access 7 Nov 2006 1,120
10 The Pharmacological Potential of Mushrooms Ulrike Lindequist, Timo H. J. Niedermeyer, Wolf‐Dieter Jülich · Evidence-based Complementary and Alternative Medicine Open access 2005 1,046
11 Plant-Derived Natural Products: A Source for Drug Discovery and Development Noureddine Chaachouay, Lahcen Zidane · Drugs and Drug Candidates Open access 19 Feb 2024 1,036
12 Efficacy and Safety of the Oral Neuraminidase Inhibitor Oseltamivir in Treating Acute Influenza John J. Treanor, Frederick G. Hayden, Peter S. Vrooman et al. · JAMA 23 Feb 2000 1,025
13 Modes of Action of Herbal Medicines and Plant Secondary Metabolites Michaël Wink · Medicines Open access 8 Sep 2015 957
14 TRPM8 Is Required for Cold Sensation in Mice Ajay K. Dhaka, Amber N. Murray, Jayanti Mathur et al. · Neuron Open access May 2007 947
15 The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept ARPAD SZALLASI, Daniel N. Cortright, Charles A. Blum et al. · Nature Reviews Drug Discovery Review 27 Apr 2007 890
16 Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2 Lindsay K. Caesar, Nadja B. Cech · Natural Product Reports Open access 2019 877
17 Natural products derived from plants as a source of drugs Ciddi Veeresham · Journal of Advanced Pharmaceutical Technology amp Research Open access 2012 864
18 Interactions Between Herbal Medicines and Prescribed Drugs Angelo Antonio Izzo, Edzard Ernst · Drugs Sep 2009 801
19 Attenuated Cold Sensitivity in TRPM8 Null Mice Raymond W. Colburn, Mary Lou Lubin, Dennis J. Stone et al. · Neuron Open access May 2007 775
20 Efficacy and Safety of the Neuraminidase Inhibitor Zanamivir in the Treatment of Influenzavirus Infections Frederick G. Hayden, Albert D. M. E. Osterhaus, John J. Treanor et al. · New England Journal of Medicine Open access 25 Sep 1997 768
21 Improvement of Gastric Emptying in Diabetic Gastroparesis by Erythromycin Julie Janssens, T. L. Peeters, Gaston R. Vantrappen et al. · New England Journal of Medicine Open access 12 Apr 1990 764
22 Amphotericin B: side effects and toxicity Rafael Laniado-Laborı́n, Maria Noemí Cabrales-Vargas · Revista Iberoamericana de Micología Oct 2009 749
23 The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions, and pharmacology. Robert A. Lewis, K. Frank Austen · Journal of Clinical Investigation Open access Apr 1984 662
24 A review of the bioactivity and potential health benefits of peppermint tea ( Mentha piperita L.) Diane L. McKay, Jeffrey B. Blumberg · Phytotherapy Research 12 Jun 2006 651
25 Understanding the symptoms of the common cold and influenza Ronald Eccles · The Lancet Infectious Diseases Open access 26 Oct 2005 650
26 Harmless Herbs? A Review of the Recent Literature Edzard Ernst · The American Journal of Medicine Feb 1998 638
27 Selective Protection against Conidia by Mononuclear and against Mycelia by Polymorphonuclear Phagocytes in Resistance to Aspergillus Andreas Schaffner, Herndon Douglas, Abraham I. Braude · Journal of Clinical Investigation Open access Mar 1982 623
28 Exercise and the Regulation of Immune Functions Richard J. Simpson, Hawley Kunz, Nadia H. Agha et al. · Progress in molecular biology and translational science Book chapter 2015 616
29 The functional network of ion channels in T lymphocytes Michael D. Cahalan, K. George Chandy · Immunological Reviews ReviewOpen access Sep 2009 610
30 Best practice in research – Overcoming common challenges in phytopharmacological research Michael Heinrich, Giovanni Appendino, Thomas Efferth et al. · Journal of Ethnopharmacology Open access 14 Sep 2019 607
31 Activation of TRPV4 Channels (hVRL-2/mTRP12) by Phorbol Derivatives Hiroyuki Watanabe, John B. Davis, Darren Smart et al. · Journal of Biological Chemistry Open access Apr 2002 603
32 Clostridium difficile: its disease and toxins David M. Lyerly, Howard C. Krivan, T D Wilkins · Clinical Microbiology Reviews Open access 1988 600
33 Critical Roles of Activation-Induced Cytidine Deaminase in the Homeostasis of Gut Flora Sidonia Fagarasan, Masamichi Muramatsu, Keiichiro Suzuki et al. · Science 14 Nov 2002 600
34 The Influence of Environmental Conditions on Secondary Metabolites in Medicinal Plants: A Literature Review Poonam Pant, Sudip Pandey, Stefano Dall’Acqua · Chemistry & Biodiversity Open access 17 Sep 2021 585
35 Trends in ethnopharmacology Anwarul Hassan Gilani, Atta‐ur Rahman · Journal of Ethnopharmacology 6 Jul 2005 585
36 Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation Riina M. Luik, Bin Wang, Murali Prakriya et al. · Nature Open access Jul 2008 581
37 Glossary of Indian Medicinal Plants with Active Principles Jeffrey B. Harborne · Phytochemistry Jul 1993 573
38 Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract Harold S. Nelson, Jan Lahr, Rosemary Rule et al. · Journal of Allergy and Clinical Immunology Open access Jun 1997 573
39 Importance of ethnopharmacological studies in drug discovery: role of medicinal plants Ipek Peşin Süntar · Phytochemistry Reviews 8 Jul 2019 567
40 Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis Tetsuro Kobayashi, Martin Glatz, Keisuke Horiuchi et al. · Immunity Open access Apr 2015 565
41 Use of the Oral Neuraminidase Inhibitor Oseltamivir in Experimental Human Influenza Frederick G. Hayden, John J. Treanor, Richard Fritz et al. · JAMA 6 Oct 1999 560
42 Thymus-Derived Rosette-Forming Cells in Various Human Disease States: Cancer, Lymphoma, Bacterial and Viral Infections, and Other Diseases Joseph Wybran, H. Hugh Fudenberg · Journal of Clinical Investigation Open access May 1973 560
43 Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration David James McConkey, Pierluigi Nicotera, Pia Hartzell et al. · Archives of Biochemistry and Biophysics Feb 1989 552
44 Advances in TRP channel drug discovery: from target validation to clinical studies Ari Koivisto, Maria Gabriela Belvisi, Rachelle Gaudet et al. · Nature Reviews Drug Discovery ReviewOpen access 15 Sep 2021 550
45 Use and acceptance of complementary and alternative medicine among the general population and medical personnel: a systematic review. Michael Frass, Robert Paul Straßl, Helmut Friehs et al. · PubMed ReviewOpen access 2012 530
46 1,25-Dihydroxyvitamin D 3 : a Novel Immunoregulatory Hormone Constantine D. Tsoukas, Diego M. Provvedini, Stavros C. Manolagas · Science 29 Jun 1984 530
47 Proving that Traditional Knowledge Works: The antibacterial activity of Northern Peruvian medicinal plants Rainer Willi Bussmann, Glenn Ashley, Douglas Sharon et al. · Ethnobotany Research and Applications Open access 2 Mar 2011 530
48 Plants as sources of new antimicrobials and resistance-modifying agents Ana Cristina Abreu, Andrew J. McBain, Manuel Simões · Natural Product Reports Open access 2012 528
49 Current findings, future trends, and unsolved problems in studies of medicinal mushrooms Solomon P. Wasser · Applied Microbiology and Biotechnology 28 Dec 2010 523
50 Ergothioneine; antioxidant potential, physiological function and role in disease Irwin Kee-Mun Cheah, Barry B. Halliwell · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Open access 17 Oct 2011 522

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.