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Topic · HIV/AIDS Research and Interventions

Most cited papers in HIV/AIDS Research and Interventions

HIV/AIDS Research and Interventions

What are the most cited papers in HIV/AIDS Research and Interventions?

The most cited paper in HIV/AIDS Research and Interventions is "Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection" (Frank Joseph Palella, Kathleen M. Delaney, Anne C. Moorman et al., 1998), with 9,545 citations. Next come "Prevention of HIV-1 Infection with Early Antiretroviral Therapy" (7,006) and "Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men" (5,186).

Showing 50 of 100 papers. Every paper with more than 1,238 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection Frank Joseph Palella, Kathleen M. Delaney, Anne C. Moorman et al. · New England Journal of Medicine 26 Mar 1998 9,545
2 Prevention of HIV-1 Infection with Early Antiretroviral Therapy Myron S. Cohen et al. · New England Journal of Medicine Open access 18 Jul 2011 7,006
3 Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men Robert M. Grant et al. · New England Journal of Medicine Open access 23 Nov 2010 5,186
4 1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults Kenneth G. Castro, Jill Ward, Laurence Slutsker et al. · Clinical Infectious Diseases Oct 1993 4,364
5 Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection David D. Ho, Avidan Uriel Neumann, Alan S. Perelson et al. · Nature 1995 4,310
6 Can Treatment Adherence Be Improved by Using Rubin's Four Tendencies Framework to Understand a Patient's Response to Expectations Jeremy M. W. Kirk, Anita MacDonald, Paul Lavender et al. · Biomedicine Hub Open access 28 Aug 2017 3,898
7 Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment Edward M. Connor, RHODA S. SPERLING, Richard D. Gelber et al. · New England Journal of Medicine Open access 3 Nov 1994 3,755
8 HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time Alan S. Perelson, Avidan Uriel Neumann, Martin H. Markowitz et al. · Science 15 Mar 1996 3,587
9 Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women Jared M. Baeten et al. · New England Journal of Medicine Open access 11 Jul 2012 3,341
10 Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection David L. Paterson, Susan Swindells, Jeffrey A. Mohr et al. · Annals of Internal Medicine 4 Jul 2000 3,332
11 Viral dynamics in human immunodeficiency virus type 1 infection Xiping Wei, Sajal K. Ghosh, Maria E. Taylor et al. · Nature 1995 3,304
12 Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy Diana Finzi, Monika Hermankova, Theodore C. Pierson et al. · Science 14 Nov 1997 3,163
13 Viral Load and Heterosexual Transmission of Human Immunodeficiency Virus Type 1 Thomas C. Quinn, Maria Joan Wawer, Nelson Kaulukusi Sewankambo et al. · New England Journal of Medicine Open access 30 Mar 2000 3,081
14 HIV and AIDS-related stigma and discrimination: a conceptual framework and implications for action Richard Guy Parker, Peter Aggleton · Social Science & Medicine 13 May 2003 2,764
15 Prognosis in HIV-1 Infection Predicted by the Quantity of Virus in Plasma John W. Mellors, Charles R. Rinaldo, Phalguni Gupta et al. · Science 24 May 1996 2,716
16 Updated research nosology for HIV-associated neurocognitive disorders Andrea Antinori et al. · Neurology Open access 4 Oct 2007 2,637
17 Adherence to Long‐Term Therapies: Evidence for Action Patricia Vernal Burkhart, Eduardo J. Sabate · Journal of Nursing Scholarship Open access Sep 2003 2,577
18 Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome Richard A. Koup, Jeffrey T. Safrit, Yaming Cao et al. · Journal of Virology Open access Jul 1994 2,515
19 Antiretroviral Treatment of Adult HIV Infection Melanie Ann Thompson, Judith A. Aberg, Jennifer F. Hoy et al. · JAMA 25 Jul 2012 2,478
20 Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women Quarraisha Abdool Karim, Salim S. Abdool Karim, Janet Frohlich et al. · Science Open access 20 Jul 2010 2,450
21 Changing AIDS-risk behavior. Jeffrey D. Fisher, William A. Fisher · Psychological Bulletin 1992 2,392
22 A systematic review of mental disorder, suicide, and deliberate self harm in lesbian, gay and bisexual people Michael King, Joanna K. Semlyen, Sharon See Tai et al. · BMC Psychiatry ReviewOpen access 18 Aug 2008 2,323
23 Snowball Sampling: A Purposeful Method of Sampling in Qualitative Research Mahin Naderifar, Hamideh Goli, Fereshteh Ghaljaie · Strides in development of medical education Open access 30 Sep 2017 2,298
24 Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia Joseph K. Wong, Marjan Hezareh, Huldrych Fritz Günthard et al. · Science 14 Nov 1997 2,250
25 Control of Viremia in Simian Immunodeficiency Virus Infection by CD8 + Lymphocytes Jörn E. Schmitz, Marcelo J. Kuroda, Sampa Santra et al. · Science 5 Feb 1999 2,203
26 The end of AIDS: HIV infection as a chronic disease Steven G. Deeks, Sharon R. Lewin, Diane V. Havlir · The Lancet Open access 24 Oct 2013 2,121
27 Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana Michael C. Thigpen et al. · New England Journal of Medicine Open access 11 Jul 2012 2,041
28 Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy Tae‐Wook Chun, Lieven J. Stuyver, Stephanie B. Mizell et al. · Proceedings of the National Academy of Sciences Open access 25 Nov 1997 2,027
29 Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model Reuben Granich, Charles F. Gilks, Christopher Dye et al. · The Lancet 28 Nov 2008 2,021
30 HIV Population Dynamics in Vivo: Implications for Genetic Variation, Pathogenesis, and Therapy John M. Coffin · Science 27 Jan 1995 2,003
31 The Spectrum of Engagement in HIV Care and its Relevance to Test-and-Treat Strategies for Prevention of HIV Infection Edward M. Gardner, Margaret P. McLees, John F. Steiner et al. · Clinical Infectious Diseases Open access 23 Feb 2011 1,937
32 Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral Therapy Roy M. Gulick, John W. Mellors, Diane V. Havlir et al. · New England Journal of Medicine Open access 11 Sep 1997 1,922
33 Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial Sheena McCormack et al. · The Lancet Open access 11 Sep 2015 1,919
34 Decay characteristics of HIV-1-infected compartments during combination therapy Alan S. Perelson, Paulina Essunger, Yunzhen Cao et al. · Nature May 1997 1,915
35 Changes in thymic function with age and during the treatment of HIV infection Daniel C. Douek, Richard McFarland, Philip H. Keiser et al. · Nature Dec 1998 1,912
36 Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial Barton F. Haynes et al. · New England Journal of Medicine Open access 4 Apr 2012 1,851
37 HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease Giuseppe Pantaleo, Cecilia Graziosi, James F. Demarest et al. · Nature 25 Mar 1993 1,847
38 HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells Michael R. Betts · Blood Open access 7 Feb 2006 1,843
39 Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus 1 with Zidovudine Treatment Edward M. Connor, RHODA S. SPERLING, Richard D. Gelber et al. · Obstetrical & Gynecological Survey Apr 1995 1,824
40 Marginal Structural Models to Estimate the Causal Effect of Zidovudine on the Survival of HIV-Positive Men Miguel Ángel Hernán, Babette Brumback, James M. Robins · Epidemiology Sep 2000 1,806
41 Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells Janet D'Angelo Siliciano, Joleen Kajdas, Diana Finzi et al. · Nature Medicine 18 May 2003 1,769
42 Antiretroviral Therapy for the Prevention of HIV-1 Transmission Myron S. Cohen et al. · New England Journal of Medicine Open access 18 Jul 2016 1,760
43 Family Rejection as a Predictor of Negative Health Outcomes in White and Latino Lesbian, Gay, and Bisexual Young Adults Caitlin Ryan, David M. Huebner, Rafael M. Díaz et al. · PEDIATRICS 29 Dec 2008 1,737
44 Interaction of silver nanoparticles with HIV-1 Jose Luis Elechiguerra, Justin L. Burt, José Rubén Morones‐Ramírez et al. · Journal of Nanobiotechnology Open access Jun 2005 1,719
45 Detection of AIDS Virus in Macrophages in Brain Tissue from AIDS Patients with Encephalopathy Scott Koenig, Howard Eliot Gendelman, Jan Marc Orenstein et al. · Science 5 Sep 1986 1,706
46 Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies ‡ · The Lancet Open access Jul 2008 1,683
47 Global, regional, and national levels and causes of maternal mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 Nicholas J Kassebaum et al. · The Lancet Open access349 authors 2 May 2014 1,682
48 The AIDS dementia complex: I. Clinical features BRADFORD A. NAVIA, Barry D. Jordan, Richard W. Price · Annals of Neurology Jun 1986 1,674
49 On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection Jean‐Michel Molina et al. · New England Journal of Medicine Open access Dec 2015 1,670
50 Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial Laura A. Guay, Philippa Musoke, Thomas R. Fleming et al. · The Lancet Open access Sep 1999 1,654

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.