Topic · Hops Chemistry and Applications
Most cited papers in Hops Chemistry and Applications
What are the most cited papers in Hops Chemistry and Applications?
The most cited paper in Hops Chemistry and Applications is "The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer" (Elliott Middleton, Chithan Kandaswami, Theoharis Constantin Theoharides, 2000), with 4,876 citations. Next come "NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase" (2,184) and "Molecular targets of dietary agents for prevention and therapy of cancer" (1,761).
Showing 50 of 100 papers. Every paper with more than 260 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer Elliott Middleton, Chithan Kandaswami, Theoharis Constantin Theoharides · Pharmacological Reviews | Dec 2000 | 4,876 |
| 2 | NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase Osman Nidai Özeş, Lindsey D. Mayo, Jason A. Gustin et al. · Nature | Sep 1999 | 2,184 |
| 3 | Molecular targets of dietary agents for prevention and therapy of cancer Bharat Bhushan Aggarwal, Shishir Shishodia · Biochemical Pharmacology | 24 Feb 2006 | 1,761 |
| 4 | Phyto-oestrogens and Western Diseases Herman Adlercreutz, Witold Mazur · Annals of Medicine | 1997 | 1,286 |
| 5 | Platelet-activating factor. Evidence for 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators). Constantinos Alexandros Demopoulos, R. Neal Pinckard, D J Hanahan · Journal of Biological Chemistry | Oct 1979 | 1,207 |
| 6 | Review of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirits? Eric B Rimm, Arthur Klatsky, Diederick E. Grobbee et al. · BMJ | 23 Mar 1996 | 1,000 |
| 7 | IMMUNOLOGICAL STUDIES CONCERNING THE NEPHRITIS OF SYSTEMIC LUPUS ERYTHEMATOSUS David Koffler, Peter H. Schur, Henry G. Kunkel · The Journal of Experimental Medicine | Oct 1967 | 883 |
| 8 | Antioxidant and anti-inflammatory activities of quercetin and its derivatives Marija M. Lesjak, Ivana N. Beara, Nataša Đ. Simin et al. · Journal of Functional Foods | 3 Nov 2017 | 858 |
| 9 | Resveratrol: A molecule whose time has come? And gone? George J. Soleas, Eleftherios P. Diamandis, David M. Goldberg · Clinical Biochemistry | Mar 1997 | 846 |
| 10 | Apigenin: A Promising Molecule for Cancer Prevention Sanjeev Shukla, Sanjay Gupta · Pharmaceutical Research | 19 Mar 2010 | 827 |
| 11 | Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals Subash C. Gupta, Ji Hye Kim, Sahdeo Prasad et al. · Cancer and Metastasis Reviews | 24 Aug 2010 | 806 |
| 12 | Effect of Plant Flavonoids on Immune and Inflammatory Cell Function Elliott Middleton · Advances in experimental medicine and biology | 1998 | 740 |
| 13 | Antioxidant Effects of Some Ginger Constituents Hiroe Kikuzaki, Nobuji Nakatani · Journal of Food Science | Nov 1993 | 723 |
| 14 | Xanthohumol and related prenylflavonoids from hops and beer: to your good health! Jan Frederik Stevens, Jonathan E. Page · Phytochemistry | May 2004 | 674 |
| 15 | Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450 Petr Hodek, Pavel Trefil, Marie Stiborová · Chemico-Biological Interactions | 2002 | 651 |
| 16 | GLUTATHIONE S-TRANSFERASES: GENE STRUCTURE, REGULATION, AND BIOLOGICAL FUNCTION C.B. Pickett, Albert Lu · Annual Review of Biochemistry | Jun 1989 | 626 |
| 17 | Multi-targeted therapy of cancer by genistein Sanjeev Banerjee, Yiwei Li, Zhiwei Peter Wang et al. · Cancer Letters | 20 May 2008 | 621 |
| 18 | Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice Hossein Hosseinzadeh, Hani M Younesi · BMC Pharmacology | 15 Mar 2002 | 606 |
| 19 | Phytotherapy of hypertension and diabetes in oriental Morocco Abderrahim Ziyyat, Abdelkhaleq Legssyer, Hassane Mekhfi et al. · Journal of Ethnopharmacology | Sep 1997 | 588 |
| 20 | Role of ginsenosides, the main active components of Panax ginseng , in inflammatory responses and diseases Ji Hye Kim, Young‐Su Yi, Mi‐Yeon Kim et al. · Journal of Ginseng Research | 22 Aug 2016 | 572 |
| 21 | Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid. Min-Nung Huang, Chi‐Tang Ho, Zhi Yuan Wang et al. · PubMed | Feb 1994 | 553 |
| 22 | Wine, Beer, Alcohol and Polyphenols on Cardiovascular Disease and Cancer Sara Arranz, Gemma Chiva‐Blanch, Palmira Valderas-Martínez et al. · Nutrients | 10 Jul 2012 | 544 |
| 23 | Pharmacological potential of ginseng and its major component ginsenosides Zubair Ahmed Ratan, Mohammad Faisal Haidere, Yo Han Hong et al. · Journal of Ginseng Research | 25 Mar 2020 | 543 |
| 24 | Pharmacognostic and pharmacological profile of Humulus lupulus L. Paola Zanoli, Manuela Zavatti · Journal of Ethnopharmacology | 21 Jan 2008 | 543 |
| 25 | A review of the clinical effects of phytoestrogens. David C. Knight, John Eden · PubMed | May 1996 | 523 |
| 26 | The potential health effects of dietary phytoestrogens Ivonne M.C.M. Rietjens, Jochem Louisse, Karsten Beekmann · British Journal of Pharmacology | 13 Oct 2016 | 496 |
| 27 | The Aloe vera phenomenon: A review of the properties and modern uses of the leaf parenchyma gel Douglas J. C. Grindlay, Tom A. Reynolds · Journal of Ethnopharmacology | Jun 1986 | 491 |
| 28 | Molecular effects of genistein on estrogen receptor mediated pathways Thomas T. Y. Wang, Neeraja Sathyamoorthy, James Ming Phang · Carcinogenesis | 1996 | 491 |
| 29 | Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis Jens Kjeldsen‐Kragh, C F Borchgrevink, EVEN LÆRUM et al. · The Lancet | Oct 1991 | 488 |
| 30 | Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines Kaname Nakatani, Devon A. Thompson, Andreas Barthel et al. · Journal of Biological Chemistry | Jul 1999 | 475 |
| 31 | Administration of Wine and Grape Juice Inhibits In Vivo Platelet Activity and Thrombosis in Stenosed Canine Coronary Arteries Heather S. Demrow, P. R. Slane, John D. Folts · Circulation | 15 Feb 1995 | 457 |
| 32 | Beer spoilage bacteria and hop resistance Kanta Sakamoto, Wil N. Konings · International Journal of Food Microbiology | 12 Sep 2003 | 449 |
| 33 | Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer Nam Deuk Kim, Rajendra G. Mehta, Weiping Yu et al. · Breast Cancer Research and Treatment | Feb 2002 | 447 |
| 34 | Antioxidant and eicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids Shay Yehoshua Schubert, Ephraim Philip Lansky, Ishak Neéman · Journal of Ethnopharmacology | Jul 1999 | 444 |
| 35 | Anthocyanin‐ and hydrolyzable tannin‐rich pomegranate fruit extract modulates MAPK and NF‐κB pathways and inhibits skin tumorigenesis in CD‐1 mice Farrukh Afaq, Mohammad Saleem, Christian G. Krueger et al. · International Journal of Cancer | 28 Sep 2004 | 440 |
| 36 | Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis Hongming Lv, Qinmei Liu, Zhongmei Wen et al. · Redox Biology | 2 Mar 2017 | 436 |
| 37 | Evaluation of Estrogenic Activity of Plant Extracts for the Potential Treatment of Menopausal Symptoms Jianghua Liu, Joanna E. Burdette, Haiyan Xu et al. · Journal of Agricultural and Food Chemistry | 24 Mar 2001 | 432 |
| 38 | Red Wine Polyphenols Enhance Endothelial Nitric Oxide Synthase Expression and Subsequent Nitric Oxide Release From Endothelial Cells Jürgen F. Leikert, Thomas R Räthel, Paulus Wohlfart et al. · Circulation | 23 Sep 2002 | 424 |
| 39 | Dietary Natural Products for Prevention and Treatment of Liver Cancer Yue Zhou, Ya Li, Tong Zhou et al. · Nutrients | 10 Mar 2016 | 413 |
| 40 | Cancer chemopreventive activity of Xanthohumol, a natural product derived from hop. Clarissa Gerhäuser, Axel Alt, Elke H. Heiß et al. · PubMed | Sep 2002 | 413 |
| 41 | Beer constituents as potential cancer chemopreventive agents Clarissa Gerhäuser · European Journal of Cancer | 14 Jun 2005 | 410 |
| 42 | Effect of St John's Wort on Drug Metabolism by Induction of Cytochrome P450 3A4 Enzyme John Seth Markowitz · JAMA | 16 Sep 2003 | 405 |
| 43 | Pharmacological and medical applications of Panax ginseng and ginsenosides: a review for use in cardiovascular diseases Jong‐Hoon Kim · Journal of Ginseng Research | 23 Oct 2017 | 404 |
| 44 | Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines C. L. Miranda, Jan Frederik Stevens, Angela Helmrich et al. · Food and Chemical Toxicology | Apr 1999 | 399 |
| 45 | Inhibition of 7,12-Dimethylbenz(a)anthracene-Induced Skin Tumorigenesis in C57BL/6 Mice by Sulforaphane Is Mediated by Nuclear Factor E2–Related Factor 2 Changjiang Xu, Mou‐Tuan Huang, Guoxiang Shen et al. · Cancer Research | 15 Aug 2006 | 385 |
| 46 | Flavanones, chalcones and dihydrochalcones - nature, occurrence and dietary burden Francisco A. Tom�s-Barber�n, Michael Newton Clifford · Journal of the Science of Food and Agriculture | 15 May 2000 | 377 |
| 47 | Synthesis of Chalcones Derivatives and Their Biological Activities: A Review Nadia A. A. Elkanzi, Hajer Hrichi, Ruba A. Alolayan et al. · ACS Omega | 2 Aug 2022 | 364 |
| 48 | Pathophysiology of irradiated skin and breast John O. Archambeau, Richard D. Pezner, Todd H. Wasserman · International Journal of Radiation Oncology*Biology*Physics | Mar 1995 | 364 |
| 49 | Effect of Genistein on In Vitro and In Vivo Models of Cancer Stephen H. Barnes · Journal of Nutrition | Mar 1995 | 363 |
| 50 | Identification of a Potent Phytoestrogen in Hops (Humulus lupulus L.) and Beer S. R. Milligan, Jyotishmita Kalita, Arne Heyerick et al. · The Journal of Clinical Endocrinology & Metabolism | Jun 1999 | 357 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.