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Most cited papers in Hormonal and reproductive studies

What are the most cited papers in Hormonal and reproductive studies?

The most cited paper in Hormonal and reproductive studies is "The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction" (Raymond C. Rosen, Alan J. Riley, Gorm Wagner et al., 1997), with 5,912 citations. Next come "Sexual Dysfunction in the United States" (5,146) and "Efficacy and Safety of Tadalafil Monotherapy for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: A Meta-Analysis" (4,545).

Showing 50 of 100 papers. Every paper with more than 919 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction Raymond C. Rosen, Alan J. Riley, Gorm Wagner et al. · Urology Jun 1997 5,912
2 Sexual Dysfunction in the United States Edward O. Laumann, Anthony Paik, Raymond C. Rosen · JAMA 10 Feb 1999 5,146
3 Efficacy and Safety of Tadalafil Monotherapy for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: A Meta-Analysis Yang Dong, Lin Hao, Zhenduo Shi et al. · Urologia Internationalis Review 2013 4,545
4 Screening and Prostate-Cancer Mortality in a Randomized European Study Fritz H. Schröder et al. · New England Journal of Medicine Open access 18 Mar 2009 4,042
5 A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum Alex T. Vermeulen, L. Verdonck, Jean‐Marc Kaufman · The Journal of Clinical Endocrinology & Metabolism Oct 1999 3,751
6 The Diagnosis of Polycystic Ovary Syndrome during Adolescence Selma Feldman Witchel, Sharon E. Oberfield, Robert L. Rosenfield et al. · Hormone Research in Paediatrics Open access 2015 3,108
7 Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction RC Rosen, JC Cappelleri, MD Smith et al. · International Journal of Impotence Research Dec 1999 3,073
8 World Health Organization reference values for human semen characteristics*‡ Trevor G. Cooper, Elizabeth A. Noonan, Sigrid von Eckardstein et al. · Human Reproduction Update 24 Nov 2009 2,857
9 Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy Men Sherman Mitchell Harman, E. Jeffrey Metter, Jordan D. Tobin et al. · The Journal of Clinical Endocrinology & Metabolism Open access Feb 2001 2,701
10 Two Receptor Systems for Corticosterone in Rat Brain: Microdistribution and Differential Occupation Johannes M. H. M. Reul, E. R. de Kloet · Endocrinology Dec 1985 2,582
11 Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer Chris Tran, Samedy Ouk, Nicola J. Clegg et al. · Science Open access 9 Apr 2009 2,341
12 Molecular determinants of resistance to antiandrogen therapy Charlie D. Chen, Derek S. Welsbie, Chris Tran et al. · Nature Medicine 21 Dec 2003 2,291
13 Design and End Points of Clinical Trials for Patients With Progressive Prostate Cancer and Castrate Levels of Testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group Howard I. Scher, Susan Halabi, Ian F. Tannock et al. · Journal of Clinical Oncology Open access 28 Feb 2008 2,267
14 Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline Ricardo Azziz, Enrico Carmina, Didier Dewailly et al. · The Journal of Clinical Endocrinology & Metabolism Open access 30 Aug 2006 2,162
15 Organic Causes of Erectile Dysfunction in Men Under 40 Wesley W. Ludwig, Michael Phillips · Urologia Internationalis Open access 21 Nov 2013 2,160
16 Estrogen plus Progestin and the Risk of Coronary Heart Disease JoAnn E. Manson, Judith A. Hsia, Karen Johnson et al. · New England Journal of Medicine Open access 6 Aug 2003 2,077
17 Some Studies of the Protein-Binding of Steroids and Their Application to the Routine Micro and Ultramicro Measurement of Various Steroids in Body Fluids by Competitive Protein-Binding Radioassay1 Beverley E. Pearson Murphy · The Journal of Clinical Endocrinology & Metabolism Jul 1967 2,004
18 Testosterone Therapy in Men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice Guideline Shalender Bhasin, Glenn R. Cunningham, Frances J. Hayes et al. · The Journal of Clinical Endocrinology & Metabolism Jun 2010 1,962
19 The American Urological Association Symptom Index for Benign Prostatic Hyperplasia Michael J. Barry, Floyd Jackson Fowler, Michael P. O’Leary et al. · The Journal of Urology 22 Dec 2016 1,950
20 Cardiovascular Disease Outcomes During 6.8 Years of Hormone Therapy Deborah G. Grady, David Herrington, Vera Bittner et al. · JAMA 3 Jul 2002 1,944
21 Age Trends in the Level of Serum Testosterone and Other Hormones in Middle-Aged Men: Longitudinal Results from the Massachusetts Male Aging Study Henry A. Feldman, Christopher Longcope, Carol A. Derby et al. · The Journal of Clinical Endocrinology & Metabolism Feb 2002 1,809
22 Androgen Receptor in Prostate Cancer Cynthia A. Heinlein, Chawnshang Chang · Endocrine Reviews Apr 2004 1,801
23 Testosterone Therapy in Men With Hypogonadism: An Endocrine Society* Clinical Practice Guideline Shalender Bhasin, Juan Pablo Brito, Glenn R. Cunningham et al. · The Journal of Clinical Endocrinology & Metabolism 17 Mar 2018 1,718
24 Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones* William B. Pratt, David O. Toft · Endocrine Reviews Open access Jun 1997 1,702
25 EICOSAPENTAENOIC ACID AND PREVENTION OF THROMBOSIS AND ATHEROSCLEROSIS? J. Dyerberg · The Lancet Jul 1978 1,690
26 The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in Normal Men Shalender Bhasin, Thomas W. Storer, Nancy Berman et al. · New England Journal of Medicine Open access 4 Jul 1996 1,684
27 Determination of the estrous cycle phases of rats: some helpful considerations Fernanda Klein Marcondes, Fabio Bianchi, Ana Paula Tanno · Brazilian Journal of Biology Open access Nov 2002 1,564
28 Persistent DDT metabolite p,p'–DDE is a potent androgen receptor antagonist WILLIAM R. KELCE, Christy R. Stone, Susan C. Laws et al. · Nature Jun 1995 1,547
29 Identification of Late-Onset Hypogonadism in Middle-Aged and Elderly Men Frederick C. W. Wu, Abdelouahid Tajar, Jennifer M. Beynon et al. · New England Journal of Medicine Open access 16 Jun 2010 1,540
30 The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis Gürkan Bozdağ, Sezcan Mümüşoğlu, Dila Zengin et al. · Human Reproduction ReviewOpen access 22 Sep 2016 1,535
31 Adverse Events Associated with Testosterone Administration Shehzad Basaria et al. · New England Journal of Medicine Open access 30 Jun 2010 1,499
32 A Controlled Trial of Leuprolide with and without Flutamide in Prostatic Carcinoma E. David Crawford, Mario A. Eisenberger, David G. McLeod et al. · New England Journal of Medicine 17 Aug 1989 1,484
33 Androgen Receptor Defects: Historical, Clinical, and Molecular Perspectives* Charmian A. Quigley, Alessandra De Bellis, Keith B. Marschke et al. · Endocrine Reviews Jun 1995 1,466
34 Diabetes and Cardiovascular Disease During Androgen Deprivation Therapy for Prostate Cancer Nancy Lynn Keating, A. James O’Malley, Matthew Raymond Smith · Journal of Clinical Oncology Open access 18 Sep 2006 1,461
35 Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth Bruce Montgomery, Elahe A. Mostaghel, Robert L. Vessella et al. · Cancer Research Open access Jun 2008 1,427
36 The Degree of Masculine Differentiation of Obesities Jean Vague · American Journal of Clinical Nutrition Feb 1956 1,419
37 Molecular Biology of Steroid Hormone Synthesis* Walter L. Miller · Endocrine Reviews Aug 1988 1,410
38 Age Changes and Sex Differences in Serum Dehydroepiandrosterone Sulfate Concentrations throughout Adulthood Norman Orentreich∥, JOEL L. BRIND, Ronald L. Rizer et al. · The Journal of Clinical Endocrinology & Metabolism Sep 1984 1,364
39 EAU Guidelines on Prostate Cancer. Part II: Treatment of Advanced, Relapsing, and Castration-Resistant Prostate Cancer Axel Heidenreich, Patrick J. Bastian, Joaquim Bellmunt et al. · European Urology 12 Nov 2013 1,361
40 Sex Differences of Endogenous Sex Hormones and Risk of Type 2 Diabetes Eric L. Ding, Yiqing Song, Vasanti Malik et al. · JAMA 14 Mar 2006 1,361
41 The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences Aytaç, Mckinlay, Krane · British Journal of Urology Jul 1999 1,361
42 Postmenopausal Estrogen and Progestin Use and the Risk of Cardiovascular Disease Francine Grodstein, Meir J. Stampfer, JoAnn E. Manson et al. · New England Journal of Medicine Open access 15 Aug 1996 1,327
43 Plasma Concentration of LH, FSH, Prolactin, Progesterone and Estradiol-17β Throughout the 4-Day Estrous Cycle of the Rat Roy Lovell Butcher, William E. Collins, NICHOLAS W. FUGO · Endocrinology Jun 1974 1,314
44 Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism Julianne Imperato‐McGinley, Luis Guerrero, Teófilo Gautier et al. · Science 27 Dec 1974 1,270
45 Erectile Dysfunction Tom F. Lue · New England Journal of Medicine 15 Jun 2000 1,265
46 Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency* Perrin C. White, Phyllis Speiser · Endocrine Reviews Jun 2000 1,257
47 Transport of Steroid Hormones: Binding of 21 Endogenous Steroids to Both Testosterone-Binding Globulin and Corticosteroid-Binding Globulin in Human Plasma James F. Dunn, BRUCE C. NISULA, David Rodbard · The Journal of Clinical Endocrinology & Metabolism Jul 1981 1,255
48 Guidelines on Male Sexual Dysfunction: Erectile Dysfunction and Premature Ejaculation Konstantinos Hatzimouratidis, Edouard Amar, Ian Eardley et al. · European Urology 21 Feb 2010 1,229
49 Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society* Clinical Practice Guideline Phyllis Speiser, Wiebke Arlt, Richard Joseph Auchus et al. · The Journal of Clinical Endocrinology & Metabolism Open access 27 Sep 2018 1,225
50 Postmenopausal Hormone Therapy and Mortality Francine Grodstein, Meir J. Stampfer, Graham A. Colditz et al. · New England Journal of Medicine Open access 19 Jun 1997 1,198

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.