Most cited papers in Inflammation biomarkers and pathways
What are the most cited papers in Inflammation biomarkers and pathways?
The most cited paper in Inflammation biomarkers and pathways is "Myeloid-derived suppressor cells as regulators of the immune system" (Dmitry I. Gabrilovich, Srinivas Nagaraj, 2009), with 6,796 citations. Next come "The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases" (3,182) and "TREM2 Variants in Alzheimer's Disease" (3,108).
Showing 50 of 100 papers. Every paper with more than 567 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Myeloid-derived suppressor cells as regulators of the immune system Dmitry I. Gabrilovich, Srinivas Nagaraj · Nature reviews. Immunology | 7 Feb 2009 | 6,796 |
| 2 | The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases Susanne Krasemann et al. · Immunity | Sep 2017 | 3,182 |
| 3 | TREM2 Variants in Alzheimer's Disease Rita João Guerreiro et al. · New England Journal of Medicine | 14 Nov 2012 | 3,108 |
| 4 | Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards Vincenzo Bronte, Sven Brandau, Shu‐Hsia Chen et al. · Nature Communications | 6 Jul 2016 | 2,806 |
| 5 | The immunopathogenesis of sepsis Jonathan B. Cohen · Nature | Dec 2002 | 2,766 |
| 6 | Identification of a unique TGF-β–dependent molecular and functional signature in microglia Oleg Butovsky, Mark P. Jedrychowski, Craig Stephen Moore et al. · Nature Neuroscience | 8 Dec 2013 | 2,717 |
| 7 | Variant of TREM2 Associated with the Risk of Alzheimer's Disease Thorlákur Jónsson et al. · New England Journal of Medicine | 14 Nov 2012 | 2,654 |
| 8 | Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia Kevin J. Tracey, Yuman Fong, DAVID G. HESSE et al. · Nature | Dec 1987 | 2,477 |
| 9 | Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin Bruce Beutler, Ian W. Milsark, Anthony Cerami · Science | 30 Aug 1985 | 2,374 |
| 10 | Microglial M1/M2 polarization and metabolic states Rubén Orihuela, Christopher A. McPherson, G. Jean Harry · British Journal of Pharmacology | 20 Mar 2015 | 2,136 |
| 11 | Proinflammatory Cytokines Charles Anthony Dinarello · CHEST Journal | Aug 2000 | 2,054 |
| 12 | The immunopathology of sepsis and potential therapeutic targets Tom van der Poll, Frank L. van de Veerdonk, Brendon P. Scicluna et al. · Nature reviews. Immunology | 24 Apr 2017 | 2,015 |
| 13 | Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity Filippo Veglia, Emilio Sanseviero, Dmitry I. Gabrilovich · Nature reviews. Immunology | Feb 2021 | 1,936 |
| 14 | Myeloid-derived suppressor cells coming of age Filippo Veglia, Michela Perego, Dmitry I. Gabrilovich · Nature Immunology | 4 Jan 2018 | 1,839 |
| 15 | TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model Yaming Wang, Marina Cella, Kaitlin Mallinson et al. · Cell | 26 Feb 2015 | 1,836 |
| 16 | Peripheral Blood “Endothelial Progenitor Cells” Are Derived From Monocyte/Macrophages and Secrete Angiogenic Growth Factors Jalees Rehman, Jingling Li, Christie M. Orschell et al. · Circulation | 3 Mar 2003 | 1,688 |
| 17 | DAMP-sensing receptors in sterile inflammation and inflammatory diseases Tao Gong, Lei Liu, Wei Jiang et al. · Nature reviews. Immunology | 26 Sep 2019 | 1,680 |
| 18 | Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment Jonas Schulte-Schrepping et al. · Cell | 5 Aug 2020 | 1,642 |
| 19 | Criteria for the diagnosis of familial mediterranean fever Avi Livneh, Pnina Langevitz, Deborah Zemer et al. · Arthritis & Rheumatism | Oct 1997 | 1,598 |
| 20 | Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration Aleksandra Deczkowska, Hadas Keren‐Shaul, Assaf Weiner et al. · Cell | May 2018 | 1,560 |
| 21 | IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. Z Xing, Jack Gauldie, Gerard Cox et al. · Journal of Clinical Investigation | 15 Jan 1998 | 1,510 |
| 22 | Human Endothelial Progenitor Cells From Type II Diabetics Exhibit Impaired Proliferation, Adhesion, and Incorporation Into Vascular Structures Oren M. Tepper, Robert D. Galiano, Jennifer M. Capla et al. · Circulation | 25 Nov 2002 | 1,461 |
| 23 | THP-1 cell line: An in vitro cell model for immune modulation approach Wasaporn Preteseille Chanput, Jurriaan J. Mes, Harry J. Wichers · International Immunopharmacology | 14 Aug 2014 | 1,449 |
| 24 | Sepsis biomarkers: a review Charalampos N. Pierrakos, Jean‐Louis Vincent · Critical Care | 9 Feb 2010 | 1,408 |
| 25 | Endotoxin tolerance: new mechanisms, molecules and clinical significance Subhra Kumar Biswas, Eduardo López‐Collazo · Trends in Immunology | 25 Sep 2009 | 1,334 |
| 26 | Cutting Edge: Inflammatory Responses Can Be Triggered by TREM-1, a Novel Receptor Expressed on Neutrophils and Monocytes Axel Bouchon, Jes Dietrich, Marco Colonna · The Journal of Immunology | May 2000 | 1,310 |
| 27 | Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease Yingyue Zhou et al. · Nature Medicine | 2020 | 1,249 |
| 28 | Characterization of Two Types of Endothelial Progenitor Cells and Their Different Contributions to Neovasculogenesis Jin Wuk Hur, Chang‐Hwan Yoon, Hyo‐Soo Kim et al. · Arteriosclerosis Thrombosis and Vascular Biology | 30 Dec 2003 | 1,203 |
| 29 | Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2 Kazuya Takahashi, Christian D.P. Rochford, Harald Neumann · The Journal of Experimental Medicine | 21 Feb 2005 | 1,147 |
| 30 | Microglial cell origin and phenotypes in health and disease Kaoru Saijo, Christopher K. Glass · Nature reviews. Immunology | 25 Oct 2011 | 1,129 |
| 31 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease Rebecca C. Sims et al. · Nature Genetics | 17 Jul 2017 | 1,122 |
| 32 | TREM-1 amplifies inflammation and is a crucial mediator of septic shock Axel Bouchon, Fabio Facchetti, Markus A. Weigand et al. · Nature | Apr 2001 | 1,108 |
| 33 | Reduced Number of Circulating Endothelial Progenitor Cells Predicts Future Cardiovascular Events Caroline Schmidt‐Lucke, Lothar Rössig, Stephan Fichtlscherer et al. · Circulation | Jun 2005 | 1,080 |
| 34 | Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases Agata Buonacera, Benedetta Stancanelli, Michele Colaci et al. · International Journal of Molecular Sciences | 26 Mar 2022 | 1,062 |
| 35 | Plasma Cytokine and Endotoxin Levels Correlate with Survival in Patients with the Sepsis Syndrome Larry C. Casey, Robert A. Balk, Roger C. Bone · Annals of Internal Medicine | 15 Oct 1993 | 1,062 |
| 36 | Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected Douglas Marvel, Dmitry I. Gabrilovich · Journal of Clinical Investigation | 12 Jul 2015 | 1,057 |
| 37 | ROLE OF C5A IN INFLAMMATORY RESPONSES Ren-Feng Guo, Peter A. Ward · Annual Review of Immunology | 11 Feb 2005 | 1,032 |
| 38 | Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer Kai Li, Houhui Shi, Benxia Zhang et al. · Signal Transduction and Targeted Therapy | 7 Oct 2021 | 998 |
| 39 | SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology Flavio Protasio Veras et al. · The Journal of Experimental Medicine | Sep 2020 | 987 |
| 40 | Inflammatory Markers and Onset of Cardiovascular Events Matteo Cesari, Brenda W.J.H. Penninx, Anne B. Newman et al. · Circulation | 20 Oct 2003 | 983 |
| 41 | Acute Lung Injury: A Clinical and Molecular Review Yasmeen M. Butt, ANNA K. KURDOWSKA, Timothy Craig Allen · Archives of Pathology & Laboratory Medicine | 30 Mar 2016 | 935 |
| 42 | TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques Yaming Wang, Tyler Kent Ulland, Jason D. Ulrich et al. · The Journal of Experimental Medicine | 18 Apr 2016 | 899 |
| 43 | Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study Emma E. Davenport, Katie L. Burnham, Jayachandran Radhakrishnan et al. · The Lancet Respiratory Medicine | 22 Feb 2016 | 886 |
| 44 | Pro‐ versus Anti‐inflammatory Cytokine Profile in Patients with Severe Sepsis: A Marker for Prognosis and Future Therapeutic Options Charalambos A. Gogos, Eugenia Drosou, Harry P. Bassaris et al. · The Journal of Infectious Diseases | 2000 | 886 |
| 45 | Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype Alvar G.N. Agustí, Lisa D Edwards, Stephen I. Rennard et al. · PLoS ONE | 18 May 2012 | 860 |
| 46 | Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients Jennifer S. Ko, Arnold H. Zea, Brian I. Rini et al. · Clinical Cancer Research | 10 Mar 2009 | 859 |
| 47 | Physical Training Increases Endothelial Progenitor Cells, Inhibits Neointima Formation, and Enhances Angiogenesis Ulrich Laufs, Nikos Werner, Andreas Link et al. · Circulation | 22 Dec 2003 | 855 |
| 48 | TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis Gernot Kleinberger et al. · Science Translational Medicine | 2 Jul 2014 | 851 |
| 49 | TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy Peng Yuan, Carlo Condello, Christopher Dirk Keene et al. · Neuron | May 2016 | 850 |
| 50 | Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function Thomas Condamine, Dmitry I. Gabrilovich · Trends in Immunology | 9 Nov 2010 | 850 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.