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Most cited papers in Influenza Virus Research Studies

What are the most cited papers in Influenza Virus Research Studies?

The most cited paper in Influenza Virus Research Studies is "Innate Immune Recognition" (Charles A. Janeway, Ruslan M. Medzhitov, 2002), with 8,439 citations. Next come "Toll-like receptor signalling" (8,340) and "Detecting influenza epidemics using search engine query data" (4,439).

Showing 50 of 99 papers. Every paper with more than 1,221 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Innate Immune Recognition Charles A. Janeway, Ruslan M. Medzhitov · Annual Review of Immunology Review Apr 2002 8,439
2 Toll-like receptor signalling Shizuo Akira, Kiyoshi Takeda · Nature reviews. Immunology Review 30 Jun 2004 8,340
3 Detecting influenza epidemics using search engine query data Jeremy Ginsberg, Matthew H. Mohebbi, Rajan S. Patel et al. · Nature Open access 19 Nov 2008 4,439
4 Evolution and ecology of influenza A viruses Robert G. Webster, William J. Bean, Owen T. Gorman et al. · Microbiological Reviews Open access Mar 1992 4,271
5 Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States W. Thompson, David K. Shay, Eric Weintraub et al. · JAMA Open access 8 Jan 2003 3,718
6 A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury Keiji Kuba et al. · Nature Medicine Open access 10 Jul 2005 3,652
7 GISAID: Global initiative on sharing all influenza data – from vision to reality Yuelong Shu, John W. McCauley · Eurosurveillance Open access 30 Mar 2017 3,604
8 Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA Sandra S. Diebold, Tsuneyasu Kaisho, Hiroaki Hemmi et al. · Science 23 Feb 2004 3,453
9 Virus interference. I. The interferon Alick Isaacs, Jean-Michel Lindenmann · Proceedings of the Royal Society B Biological Sciences 12 Sep 1957 3,446
10 Estimates of global seasonal influenza-associated respiratory mortality: a modelling study Angela Danielle Iuliano et al. · The Lancet Open access138 authors 13 Dec 2017 3,158
11 Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin John James Skehel, Don C. Wiley · Annual Review of Biochemistry Review Jun 2000 2,734
12 Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution Ian A. Wilson, John James Skehel, Don C. Wiley · Nature 1981 2,550
13 Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans Rebecca J. Garten et al. · Science Open access 22 May 2009 2,548
14 Functional Role of Type I and Type II Interferons in Antiviral Defense Ulrike Müller, Ulrich Steinhoff, Luiz F. L. Reis et al. · Science Open access 24 Jun 1994 2,491
15 The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex Beom Seok Park, Dong Hyun Song, Ho Min Kim et al. · Nature Mar 2009 2,458
16 Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19 Yuan Huang, Chan Yang, Xin-feng Xu et al. · Acta Pharmacologica Sinica Open access 3 Aug 2020 2,421
17 Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus Rongbao Gao et al. · New England Journal of Medicine Open access 11 Apr 2013 2,357
18 Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature, 2007–2012 Heidi Jane Larson, Caitlin Jarrett, Elisabeth Eckersberger et al. · Vaccine Review 2 Mar 2014 2,341
19 Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein Jeffrey B. Ulmer, John Donnelly, Suezanne E. Parker et al. · Science 19 Mar 1993 2,326
20 Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic Gavin J. D. Smith, Dhanasekaran Vijaykrishna, Justin Bahl et al. · Nature Open access Jun 2009 2,311
21 Strategies for mitigating an influenza pandemic Neil M. Ferguson, Derek A. T. Cummings, Christophe Fraser et al. · Nature Open access 26 Apr 2006 2,300
22 Improved Estimation of Secondary Structure in Ribonucleic Acids Ignacio Tinoco, Philip N. Borer, Barbara Dengler et al. · Nature New Biology Nov 1973 2,289
23 Influenza-Associated Hospitalizations in the United States W. Thompson · JAMA 14 Sep 2004 2,244
24 Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor Fang Li, Wenhui Li, Michael Reynolds Farzan et al. · Science 15 Sep 2005 2,230
25 Evolution and ecology of influenza A viruses. R. G. Webster, W J Bean, Owen T. Gorman et al. · Microbiological Reviews Open access 1992 2,196
26 Universal primer set for the full-length amplification of all influenza A viruses E. Hoffmann, Jürgen Stech, Yi Guan et al. · Archives of Virology Open access Dec 2001 2,086
27 Into the Eye of the Cytokine Storm Jennifer R. Tisoncik, Marcus J. Korth, Cameron P. Simmons et al. · Microbiology and Molecular Biology Reviews ReviewOpen access Mar 2012 2,019
28 Global Patterns of Influenza A Virus in Wild Birds Bjorn R Olsen, Vincent J. Munster, Anders Wallensten et al. · Science 21 Apr 2006 2,013
29 Mapping the Antigenic and Genetic Evolution of Influenza Virus Derek J. Smith, Alan S. Lapedes, Jan C. de Jong et al. · Science 24 Jun 2004 1,998
30 Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings Christophe Fraser et al. · Science Open access 11 May 2009 1,970
31 Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides Veit Hornung, Simon Rothenfußer, Stefanie Britsch et al. · The Journal of Immunology May 2002 1,948
32 Bayesian Phylogeography Finds Its Roots Philippe Lemey, Andrew Rambaut, Alexei J. Drummond et al. · PLoS Computational Biology Open access 25 Sep 2009 1,939
33 Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia Menno D. de Jong, Cameron P. Simmons, Tran Tan Thanh et al. · Nature Medicine Open access 10 Sep 2006 1,917
34 MiXCR: software for comprehensive adaptive immunity profiling Dmitriy A. Bolotin, S. Poslavskii, Igor Mitrophanov et al. · Nature Methods 29 Apr 2015 1,898
35 Strategies for containing an emerging influenza pandemic in Southeast Asia Neil M. Ferguson, Derek A. T. Cummings, Simon Cauchemez et al. · Nature Open access 3 Aug 2005 1,889
36 Recognition of single-stranded RNA viruses by Toll-like receptor 7 Jennifer M. Lund, Lena Alexopoulou, Ayuko Sato et al. · Proceedings of the National Academy of Sciences Open access 19 Mar 2004 1,870
37 Rational design of potent sialidase-based inhibitors of influenza virus replication Mark von Itzstein, Wen‐Yang Wu, Gaik B. Kok et al. · Nature Jun 1993 1,868
38 Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis Michael T. Osterholm, Nicholas S. Kelley, Alfred H. Sommer et al. · The Lancet Infectious Diseases Review 14 Nov 2011 1,824
39 The history of Toll-like receptors — redefining innate immunity Luke A.J. O'Neill, Douglas Taylor Golenbock, Andrew G. Bowie · Nature reviews. Immunology Review 17 May 2013 1,753
40 The annual impact of seasonal influenza in the US: Measuring disease burden and costs Noelle‐Angelique Molinari, Ismael R. Ortega‐Sanchez, Mark L. Messonnier et al. · Vaccine 21 Apr 2007 1,751
41 Development of a Real-Time Reverse Transcriptase PCR Assay for Type A Influenza Virus and the Avian H5 and H7 Hemagglutinin Subtypes Erica Spackman, Dennis A. Senne, Thomas J. Myers et al. · Journal of Clinical Microbiology Open access 29 Aug 2002 1,743
42 Influenza Virus Transmission Is Dependent on Relative Humidity and Temperature Anice C. Lowen, Samira Mubareka, John Steel et al. · PLoS Pathogens Open access 15 Oct 2007 1,738
43 1918 Influenza: the Mother of All Pandemics Jeffery K. Taubenberger, David Michael Morens · Emerging infectious diseases Open access 2006 1,722
44 Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009 Seema Jain et al. · New England Journal of Medicine 8 Oct 2009 1,719
45 Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets Sander Herfst, Eefje J. A. Schrauwen, Martin Linster et al. · Science Open access 21 Jun 2012 1,716
46 The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides Alain Townsend · Cell 28 Mar 1986 1,712
47 Are healthcare workers’ intentions to vaccinate related to their knowledge, beliefs and attitudes? a systematic review Raúl Herzog, Ma José Álvarez-Pasquin, Camino Díaz et al. · BMC Public Health ReviewOpen access 19 Feb 2013 1,708
48 Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness David Michael Morens, Jeffery K. Taubenberger, Anthony S. Fauci · The Journal of Infectious Diseases Open access 18 Aug 2008 1,662
49 A DNA transfection system for generation of influenza A virus from eight plasmids Erich Hoffmann, Gabriele Neumann, Yoshihiro Kawaoka et al. · Proceedings of the National Academy of Sciences Open access 9 May 2000 1,661
50 Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices—United States, 2018–19 Influenza Season Lisa A. Grohskopf, Leslie Z. Sokolow, Karen R. Broder et al. · MMWR Recommendations and Reports Open access 23 Aug 2018 1,654

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.